JP5356807B2 - 原核細胞由来の組み換えｎ−グリコシル化タンパク質 - Google Patents

原核細胞由来の組み換えｎ−グリコシル化タンパク質 Download PDF

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JP5356807B2
JP5356807B2 JP2008510495A JP2008510495A JP5356807B2 JP 5356807 B2 JP5356807 B2 JP 5356807B2 JP 2008510495 A JP2008510495 A JP 2008510495A JP 2008510495 A JP2008510495 A JP 2008510495A JP 5356807 B2 JP5356807 B2 JP 5356807B2
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recombinant
protein
glycosylated
ssp
nucleic acid
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JP2008539743A (ja
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アービ，マルクス
コワリク，ミカエル
アフジャ，ウメシュ
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アイトヘネーシシェ テフニーシェ ホフシューレ チューリッヒ
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    • C—CHEMISTRY; METALLURGY
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    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/25—Shigella (G)
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/034—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Gastroenterology & Hepatology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2008510495A 2005-05-11 2006-05-10 原核細胞由来の組み換えｎ−グリコシル化タンパク質 Active JP5356807B2 (ja)

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EP05010276 2005-05-11
EP05010276.3 2005-05-11
PCT/EP2006/004397 WO2006119987A2 (en) 2005-05-11 2006-05-10 Recombinant n-glycosylated proteins from procaryotic cells

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JP5356807B2 true JP5356807B2 (ja) 2013-12-04

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JP2012001342A Active JP5687637B2 (ja) 2005-05-11 2012-01-06 原核細胞由来の組み換えｎ−グリコシル化タンパク質
JP2013250586A Active JP5827303B2 (ja) 2005-05-11 2013-12-03 原核細胞由来の組み換えｎ−グリコシル化タンパク質

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US (3) US8753864B2 (https=)
EP (3) EP2311972B1 (https=)
JP (3) JP5356807B2 (https=)
KR (2) KR101408653B1 (https=)
CN (2) CN101360831B (https=)
AT (1) ATE483027T1 (https=)
AU (1) AU2006245969B8 (https=)
CA (1) CA2607595C (https=)
CY (1) CY1116285T1 (https=)
DE (1) DE602006017207D1 (https=)
DK (2) DK2311972T3 (https=)
ES (3) ES2353814T3 (https=)
HK (1) HK1205193A1 (https=)
HR (1) HRP20150312T1 (https=)
IL (2) IL187293A (https=)
PL (1) PL2311972T3 (https=)
PT (2) PT1888761E (https=)
SI (1) SI2311972T1 (https=)
WO (1) WO2006119987A2 (https=)

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US20140323700A1 (en) 2014-10-30
WO2006119987A2 (en) 2006-11-16
DE602006017207D1 (de) 2010-11-11
IL226857A (en) 2017-08-31
AU2006245969B2 (en) 2011-06-02
AU2006245969B8 (en) 2011-08-25
JP2008539743A (ja) 2008-11-20
JP2012100678A (ja) 2012-05-31
CN103396478A (zh) 2013-11-20
US8753864B2 (en) 2014-06-17
CA2607595A1 (en) 2006-11-16
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JP5687637B2 (ja) 2015-03-18
DK1888761T3 (da) 2010-11-01
ES2535084T3 (es) 2015-05-05
SI2311972T1 (sl) 2015-08-31
EP1888761A2 (en) 2008-02-20
WO2006119987A3 (en) 2007-03-08
KR20080048990A (ko) 2008-06-03
EP2853600A1 (en) 2015-04-01
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