JP5328365B2 - ヒドロキシケト化合物のエナンチオ選択的酵素的還元の方法 - Google Patents
ヒドロキシケト化合物のエナンチオ選択的酵素的還元の方法 Download PDFInfo
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- JP5328365B2 JP5328365B2 JP2008546207A JP2008546207A JP5328365B2 JP 5328365 B2 JP5328365 B2 JP 5328365B2 JP 2008546207 A JP2008546207 A JP 2008546207A JP 2008546207 A JP2008546207 A JP 2008546207A JP 5328365 B2 JP5328365 B2 JP 5328365B2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
-
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| Application Number | Priority Date | Filing Date | Title |
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| ATA2027/2005 | 2005-12-19 | ||
| AT0202705A AT503017B1 (de) | 2005-12-19 | 2005-12-19 | Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen |
| PCT/EP2006/012037 WO2007073875A1 (de) | 2005-12-19 | 2006-12-14 | Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen |
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| Publication Number | Publication Date |
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| JP2009519722A JP2009519722A (ja) | 2009-05-21 |
| JP5328365B2 true JP5328365B2 (ja) | 2013-10-30 |
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| JP2008546207A Expired - Fee Related JP5328365B2 (ja) | 2005-12-19 | 2006-12-14 | ヒドロキシケト化合物のエナンチオ選択的酵素的還元の方法 |
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| US (2) | US8980592B2 (sl) |
| EP (1) | EP1963516B1 (sl) |
| JP (1) | JP5328365B2 (sl) |
| KR (1) | KR101344605B1 (sl) |
| CN (1) | CN101432435A (sl) |
| AT (2) | AT503017B1 (sl) |
| AU (1) | AU2006331069B2 (sl) |
| CA (1) | CA2633583C (sl) |
| DE (1) | DE502006008961D1 (sl) |
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| PT (1) | PT1963516E (sl) |
| SI (1) | SI1963516T1 (sl) |
| TW (1) | TWI408234B (sl) |
| WO (1) | WO2007073875A1 (sl) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT504542B1 (de) * | 2006-12-07 | 2008-09-15 | Iep Gmbh | Verfahren zur enantioselektiven enzymatischen reduktion von secodionderivaten |
| TWI601825B (zh) * | 2007-09-27 | 2017-10-11 | Ｉｅｐ有限公司 | 對映異構選擇性酶催化還原中間產物之方法 |
| CN101429514B (zh) * | 2007-11-08 | 2011-06-15 | 陈依军 | 一种双羰基还原酶、其基因及其应用 |
| EP2226386A1 (de) * | 2009-03-05 | 2010-09-08 | IEP GmbH | Verfahren zur stereoselektiven enzymatischen Reduktion von Ketoverbindungen |
| CN102803233B (zh) | 2009-06-22 | 2017-03-01 | 爱思开生物制药株式会社 | 制备氨基甲酸(r)‑1‑芳基‑2‑四唑基‑乙酯的方法 |
| US8404461B2 (en) | 2009-10-15 | 2013-03-26 | SK Biopharmaceutical Co. Ltd. | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester |
| CN103228658A (zh) * | 2010-10-08 | 2013-07-31 | 卡迪拉保健有限公司 | 用于通过酶促转化制备西他列汀的中间体的方法 |
| EP3456820B1 (de) * | 2010-12-16 | 2024-06-19 | Pharmazell GmbH | Neuartige 7beta-hydroxysteroid dehydrogenase-mutanten und verfahren zur herstellung von ursodesoxycholsäure |
| ES2619338T3 (es) * | 2012-06-18 | 2017-06-26 | Olon S.P.A. | Procedimiento para la producción de 3-piperidinoles quirales sustituidos en posición 1 empleando oxidorreductasas |
| CN102978249A (zh) * | 2012-11-19 | 2013-03-20 | 苏州汉酶生物技术有限公司 | 6-氰基-（3r,5r）-二羟基己酸叔丁酯的生物制备方法 |
| CN103146591B (zh) * | 2013-01-30 | 2014-08-27 | 浙江工业大学 | 生物还原制备他汀侧链6-氰基-(3r,5r)-二羟基己酸叔丁酯及菌株 |
| CN104342410B (zh) * | 2013-07-26 | 2017-04-19 | 南京朗恩生物科技有限公司 | 一种酮还原酶突变体及其制备方法 |
| CN105713884A (zh) * | 2014-12-02 | 2016-06-29 | 安琪酵母股份有限公司 | 生物催化氢化组合物及其合成罗素伐他汀手性中间体方法 |
| US10745263B2 (en) | 2015-05-28 | 2020-08-18 | Sonicu, Llc | Container fill level indication system using a machine learning algorithm |
| US10746586B2 (en) | 2015-05-28 | 2020-08-18 | Sonicu, Llc | Tank-in-tank container fill level indicator |
| CN109913514A (zh) * | 2019-03-12 | 2019-06-21 | 江苏理工学院 | 一种固定化酶流化床连续催化合成ats-7的方法 |
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|---|---|---|---|---|
| US5324662A (en) | 1992-05-15 | 1994-06-28 | E. R. Squibb & Sons, Inc. | Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters |
| GB9512837D0 (en) * | 1995-06-23 | 1995-08-23 | Zeneca Ltd | reduction of ketone groups |
| HUP0105331A3 (en) * | 1999-12-03 | 2005-10-28 | Kaneka Corp | Novel carbonyl reductase, gene thereof and method of using the same |
| GB0011120D0 (en) | 2000-05-09 | 2000-06-28 | Avecia Ltd | Process |
| DE60315958D1 (de) * | 2002-03-18 | 2007-10-11 | Biocatalytics Inc | Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur |
| DE10327454A1 (de) * | 2003-06-18 | 2005-01-20 | Juelich Enzyme Products Gmbh | Oxidoreduktase aus Pichia capsulata |
| AT413541B (de) | 2004-05-10 | 2006-03-15 | Iep Gmbh | Verfahren zur herstellung von 2-butanol |
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2005
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| Publication number | Publication date |
|---|---|
| CA2633583A1 (en) | 2007-07-05 |
| KR20080087000A (ko) | 2008-09-29 |
| US20150152451A1 (en) | 2015-06-04 |
| EP1963516A1 (de) | 2008-09-03 |
| AT503017A4 (de) | 2007-07-15 |
| CN101432435A (zh) | 2009-05-13 |
| DK1963516T3 (da) | 2011-06-06 |
| KR101344605B1 (ko) | 2013-12-26 |
| TWI408234B (zh) | 2013-09-11 |
| ZA200805336B (en) | 2009-12-30 |
| ES2363374T3 (es) | 2011-08-02 |
| JP2009519722A (ja) | 2009-05-21 |
| AU2006331069B2 (en) | 2012-04-05 |
| AU2006331069A1 (en) | 2007-07-05 |
| EP1963516B1 (de) | 2011-02-23 |
| TW200801196A (en) | 2008-01-01 |
| SI1963516T1 (sl) | 2011-06-30 |
| PT1963516E (pt) | 2011-05-25 |
| US20090221044A1 (en) | 2009-09-03 |
| DE502006008961D1 (de) | 2011-04-07 |
| PL1963516T3 (pl) | 2011-07-29 |
| WO2007073875A1 (de) | 2007-07-05 |
| AT503017B1 (de) | 2007-07-15 |
| US8980592B2 (en) | 2015-03-17 |
| CA2633583C (en) | 2016-06-21 |
| ATE499447T1 (de) | 2011-03-15 |
| US9228214B2 (en) | 2016-01-05 |
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