JP5300477B2 - 薬理活性物質の吸収性が改善された医薬組成物 - Google Patents

薬理活性物質の吸収性が改善された医薬組成物 Download PDF

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Publication number
JP5300477B2
JP5300477B2 JP2008527720A JP2008527720A JP5300477B2 JP 5300477 B2 JP5300477 B2 JP 5300477B2 JP 2008527720 A JP2008527720 A JP 2008527720A JP 2008527720 A JP2008527720 A JP 2008527720A JP 5300477 B2 JP5300477 B2 JP 5300477B2
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Prior art keywords
pharmaceutical composition
component
pharmacologically active
fatty acid
acid
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Expired - Fee Related
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JP2008527720A
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Japanese (ja)
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JPWO2008015959A1 (ja
Inventor
正晃 三宅
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Otsuka Pharmaceutical Co Ltd
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Otsuka Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
JP2008527720A 2006-08-01 2007-07-26 薬理活性物質の吸収性が改善された医薬組成物 Expired - Fee Related JP5300477B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008527720A JP5300477B2 (ja) 2006-08-01 2007-07-26 薬理活性物質の吸収性が改善された医薬組成物

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2006209863 2006-08-01
JP2006209863 2006-08-01
PCT/JP2007/064685 WO2008015959A1 (fr) 2006-08-01 2007-07-26 Composition pharmaceutique permettant une meilleure absorption d'une substance pharmacologiquement active
JP2008527720A JP5300477B2 (ja) 2006-08-01 2007-07-26 薬理活性物質の吸収性が改善された医薬組成物

Publications (2)

Publication Number Publication Date
JPWO2008015959A1 JPWO2008015959A1 (ja) 2009-12-24
JP5300477B2 true JP5300477B2 (ja) 2013-09-25

Family

ID=38997138

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008527720A Expired - Fee Related JP5300477B2 (ja) 2006-08-01 2007-07-26 薬理活性物質の吸収性が改善された医薬組成物

Country Status (4)

Country Link
JP (1) JP5300477B2 (zh)
KR (1) KR101390695B1 (zh)
CN (1) CN101495150B (zh)
WO (1) WO2008015959A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102139115B (zh) * 2011-03-30 2012-12-05 天津红日药业股份有限公司 阿托伐他汀的环糊精包合物及其口服固体制剂的制备方法
CA2857430C (en) 2011-12-14 2019-12-03 Lts Lohmann Therapie-Systeme Ag Wafer and capsule formulations with enhanced dissolution rates for fenofibrate
CN104080450A (zh) * 2012-01-05 2014-10-01 阿拉维制药公司 扎那米韦生物利用度增强的制剂
CN105012267A (zh) * 2015-08-19 2015-11-04 海南科进生物制药有限公司 一种瑞巴派特片及其制备方法
CN105617353A (zh) * 2016-01-04 2016-06-01 李志海 一种黏菌素口服给药组合物

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5372814A (en) * 1976-12-03 1978-06-28 Scherer Ltd R P Pharmaceutical composition
JPH06502143A (ja) * 1990-10-19 1994-03-10 プロヴァリス　ユーケー　リミテッド 親油性薬剤用の２相放出配合物
JPH07196483A (ja) * 1993-11-25 1995-08-01 Taisho Pharmaceut Co Ltd 経口吸収性を改善した製剤組成物
JPH07507565A (ja) * 1992-10-02 1995-08-24 ファイザー・インク． 非イオン性表面活性剤を含有する医薬組成物
JPH10503750A (ja) * 1994-03-16 1998-04-07 アール． ピー． シェーラー リミテッド 疎水性薬剤の投与システム
JPH10231254A (ja) * 1996-12-19 1998-09-02 Dai Ichi Seiyaku Co Ltd 経口吸収改善医薬用組成物
JP2001288117A (ja) * 2000-04-05 2001-10-16 Otsuka Pharmaceut Co Ltd 医薬製剤用組成物
JP2002532539A (ja) * 1998-12-18 2002-10-02 アボット・ラボラトリーズ 脂質調節剤を含む新規な製剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1240363A (zh) * 1996-12-19 2000-01-05 第一制药株式会社 口服给药的药物组合物

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5372814A (en) * 1976-12-03 1978-06-28 Scherer Ltd R P Pharmaceutical composition
JPH06502143A (ja) * 1990-10-19 1994-03-10 プロヴァリス　ユーケー　リミテッド 親油性薬剤用の２相放出配合物
JPH07507565A (ja) * 1992-10-02 1995-08-24 ファイザー・インク． 非イオン性表面活性剤を含有する医薬組成物
JPH07196483A (ja) * 1993-11-25 1995-08-01 Taisho Pharmaceut Co Ltd 経口吸収性を改善した製剤組成物
JPH10503750A (ja) * 1994-03-16 1998-04-07 アール． ピー． シェーラー リミテッド 疎水性薬剤の投与システム
JPH10231254A (ja) * 1996-12-19 1998-09-02 Dai Ichi Seiyaku Co Ltd 経口吸収改善医薬用組成物
JP2002532539A (ja) * 1998-12-18 2002-10-02 アボット・ラボラトリーズ 脂質調節剤を含む新規な製剤
JP2001288117A (ja) * 2000-04-05 2001-10-16 Otsuka Pharmaceut Co Ltd 医薬製剤用組成物

Also Published As

Publication number Publication date
CN101495150A (zh) 2009-07-29
KR20090038481A (ko) 2009-04-20
CN101495150B (zh) 2011-06-01
KR101390695B1 (ko) 2014-04-30
WO2008015959A1 (fr) 2008-02-07
JPWO2008015959A1 (ja) 2009-12-24

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