JP5289447B2 - Ｎ，ｎ’−ビス（２−ヒドロキシベンジル）エチレンジアミン−ｎ，ｎ’−二酢酸およびその誘導体の調製方法 - Google Patents

Ｎ，ｎ’−ビス（２−ヒドロキシベンジル）エチレンジアミン−ｎ，ｎ’−二酢酸およびその誘導体の調製方法 Download PDF

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JP5289447B2
JP5289447B2 JP2010525318A JP2010525318A JP5289447B2 JP 5289447 B2 JP5289447 B2 JP 5289447B2 JP 2010525318 A JP2010525318 A JP 2010525318A JP 2010525318 A JP2010525318 A JP 2010525318A JP 5289447 B2 JP5289447 B2 JP 5289447B2
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formula
compound
ethylenediamine
compound represented
bis
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Japanese (ja)
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JP2010539212A5 (https=
JP2010539212A (ja
Inventor
ナウロッキ，アダム
ステファニアク，フィリップ
ムロツェク−ニエッコ，アニカ
オルスゼウスキー，ラドスロウ
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Prezedsiebiorstwo Produkcyjno Consultingowe Adob SpZ OOSpK
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Prezedsiebiorstwo Produkcyjno Consultingowe Adob SpZ OOSpK
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2010525318A 2007-09-20 2008-09-15 Ｎ，ｎ’−ビス（２−ヒドロキシベンジル）エチレンジアミン−ｎ，ｎ’−二酢酸およびその誘導体の調製方法 Expired - Fee Related JP5289447B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07465006.0A EP2039679B1 (en) 2007-09-20 2007-09-20 A process for the preparation of N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid and its derivatives
EP07465006.0 2007-09-20
PCT/EP2008/062269 WO2009037235A1 (en) 2007-09-20 2008-09-15 A process for the preparation of n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and its derivatives

Publications (3)

Publication Number Publication Date
JP2010539212A JP2010539212A (ja) 2010-12-16
JP2010539212A5 JP2010539212A5 (https=) 2011-10-27
JP5289447B2 true JP5289447B2 (ja) 2013-09-11

Family

ID=39665857

Family Applications (1)

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JP2010525318A Expired - Fee Related JP5289447B2 (ja) 2007-09-20 2008-09-15 Ｎ，ｎ’−ビス（２−ヒドロキシベンジル）エチレンジアミン−ｎ，ｎ’−二酢酸およびその誘導体の調製方法

Country Status (8)

Country Link
US (1) US8431734B2 (https=)
EP (1) EP2039679B1 (https=)
JP (1) JP5289447B2 (https=)
CN (1) CN101784518B (https=)
DK (1) DK2039679T3 (https=)
ES (1) ES2551880T3 (https=)
PL (1) PL2039679T3 (https=)
WO (1) WO2009037235A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2289869T3 (da) 2009-07-17 2012-09-17 Przed Prod Consultingowe Adob Sp Z O O Sp K Fremgangsmåde til fremstilling af Fe(III)-chelater af N,N´-di(2-hydroxybenzyl)-ethylendiamin-N,N´-dieddikesyre og derivater deraf
US8378134B2 (en) 2009-09-30 2013-02-19 General Electric Company Hydroxylated contrast enhancement agents
US20110077396A1 (en) * 2009-09-30 2011-03-31 General Electric Company Intermediates for hydroxylated contrast enhancement agents
US10093612B2 (en) 2015-06-25 2018-10-09 Akzo Nobel Chemicals International B.V. Process to prepare phenolic ethylenediamine diacetic acid compounds
WO2016207266A1 (en) 2015-06-25 2016-12-29 Akzo Nobel Chemicals International B.V. Process to prepare phenolic ethylenediamine diacetic acid compounds
US10793482B2 (en) * 2015-06-29 2020-10-06 Spero Energy, Inc. Compounds and compositions for delivery of nutrients and micronutrients to plants
CN108568316B (zh) * 2018-04-27 2021-03-30 华南理工大学 一类高稳定锆基手性催化剂及制备方法与其应用
CN112358422B (zh) * 2020-10-16 2023-06-23 中国辐射防护研究院 一种新型螯合剂nbed的制备方法
CN112390733A (zh) * 2020-10-16 2021-02-23 中国辐射防护研究院 一种新型螯合剂及其制备方法
KR102888292B1 (ko) * 2020-10-30 2025-11-19 주식회사 엘지화학 술포닐플루오라이드기 함유 화합물 및 이의 제조방법
EP3848349B1 (en) 2020-12-01 2023-03-15 Przedsiebiorstwo Produkcyjno-Consultingowe ADOB Sp. z o.o. A process for the preparation of salts of n,n'-disubstituted ethylenediamine-n,n'-diacetic acid derivatives and their use
US12180328B2 (en) 2021-05-04 2024-12-31 Sachem, Inc. Strong binding metal-chelating resins
TW202308755A (zh) 2021-05-04 2023-03-01 美商沙坎公司 使用大環分子的強結合金屬螯合樹脂

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
US2967196A (en) * 1955-12-06 1961-01-03 Geigy Chem Corp Ethylenediaminediacetic acids containing phenolic groups
US3038793A (en) 1955-12-06 1962-06-12 Geigy Chem Corp Treating iron deficient plants with ferric chelates of ethylenediaminediacetic acids containing phenolic groups
US3632637A (en) 1968-02-13 1972-01-04 Arthur E Martell Hydroxyaryl-containing aminocarboxylic chelating agents
US4073804A (en) * 1976-05-04 1978-02-14 Boise Cascade Corporation Producing glycine by the reductive amination of glyoxylic acid
CH602857A5 (https=) * 1976-12-10 1978-08-15 Ciba Geigy Ag
US4130582A (en) * 1977-04-19 1978-12-19 Ciba-Geigy Corporation Preparation of phenolic ethylenediaminepolycarboxylic acids
HUT41715A (en) * 1984-12-28 1987-05-28 Monsanto Co Process for preparing n-substituted alpha-aminoacids and derivatives thereof
FR2627772B1 (fr) * 1988-02-29 1990-08-17 Protex Manuf Prod Chimiq Nouveau procede de preparation de l'acide ethylene-diamine-n-n(prime)-bis(ortho-hydroxyphenylacetique) et de derives de celui-ci
IE980696A1 (en) * 1988-10-31 2000-12-13 Dow Chemical Co Chelants processing ortho ligating functionality and complexes thereof
DE4408530A1 (de) * 1994-03-14 1995-09-28 Hoechst Ag Verfahren zur Herstellung von Aminoethylglycin
US7405320B2 (en) * 1998-06-22 2008-07-29 Immunomedics, Inc. Therapeutic and diagnostic conjugates for use with multispecific antibodies
CA2394524A1 (en) * 1999-12-21 2001-06-28 Raymond J. Bergeron N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid in iron chelating therapy
BRPI0409307A (pt) * 2003-04-14 2006-04-25 Pfizer Prod Inc derivados de 3-azabiciclo[3.2.1]octano
US7884059B2 (en) * 2004-10-20 2011-02-08 Afton Chemical Corporation Oil-soluble molybdenum derivatives derived from hydroxyethyl-substituted Mannich bases

Also Published As

Publication number Publication date
WO2009037235A1 (en) 2009-03-26
ES2551880T3 (es) 2015-11-24
CN101784518B (zh) 2013-11-13
EP2039679A1 (en) 2009-03-25
US20100168469A1 (en) 2010-07-01
JP2010539212A (ja) 2010-12-16
CN101784518A (zh) 2010-07-21
HK1146403A1 (en) 2011-06-03
PL2039679T3 (pl) 2015-10-30
EP2039679B1 (en) 2015-08-12
DK2039679T3 (en) 2015-11-02
US8431734B2 (en) 2013-04-30

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