JP5256042B2 - 癌の処置のための併用療法 - Google Patents
癌の処置のための併用療法 Download PDFInfo
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- JP5256042B2 JP5256042B2 JP2008542425A JP2008542425A JP5256042B2 JP 5256042 B2 JP5256042 B2 JP 5256042B2 JP 2008542425 A JP2008542425 A JP 2008542425A JP 2008542425 A JP2008542425 A JP 2008542425A JP 5256042 B2 JP5256042 B2 JP 5256042B2
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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| US73891905P | 2005-11-22 | 2005-11-22 | |
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| PCT/US2006/045151 WO2007062093A2 (en) | 2005-11-22 | 2006-11-21 | Combination therapy for the treatment of cancer comprising a metalloprotease inhibitor |
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| JP2009516747A JP2009516747A (ja) | 2009-04-23 |
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| WO2004096139A2 (en) | 2003-04-24 | 2004-11-11 | Incyte Corporation | Aza spiro alkane derivatives as inhibitors of metalloproteases |
| MXPA06004191A (es) | 2003-10-17 | 2007-01-19 | Incyte Corp | Hidroxamatos ciclicos sustituidos en la forma inhibidores de metaloproteinasas de matriz. |
| WO2007016597A2 (en) * | 2005-07-29 | 2007-02-08 | The Regents Of The University Of California | Targeting tnf-alpha converting enzyme (tace)-dependent growth factor shedding in cancer therapy |
| WO2007143600A2 (en) | 2006-06-05 | 2007-12-13 | Incyte Corporation | Sheddase inhibitors combined with cd30-binding immunotherapeutics for the treatment of cd30 positive diseases |
| SG186656A1 (en) | 2007-12-14 | 2013-01-30 | Bristol Myers Squibb Co | Binding molecules to the human ox40 receptor |
| WO2010141543A1 (en) * | 2009-06-02 | 2010-12-09 | Targeted Molecular Diagnostics, Llc | Methods for the detection and quantitation of the p95 component of her2/neu (erbb2) |
| WO2011083391A2 (en) | 2010-01-05 | 2011-07-14 | Pfizer Inc. | Biomarkers for anti-igf-ir cancer therapy |
| MX337040B (es) | 2010-09-09 | 2016-02-09 | Pfizer | Moleculas de union a 4-1bb. |
| GB201116092D0 (en) | 2011-09-16 | 2011-11-02 | Bioceros B V | Antibodies and uses thereof |
| ES2620668T3 (es) | 2012-03-02 | 2017-06-29 | Genentech, Inc. | Derivados de amidas y sulfonamidas amido espirocíclicas |
| CN102600073B (zh) * | 2012-03-31 | 2014-01-01 | 莱普德制药有限公司 | 以乳酸酯为基础的氟维司群或其衍生物油性制剂及其制备方法 |
| NZ701324A (en) | 2012-05-04 | 2016-09-30 | Pfizer | Prostate-associated antigens and vaccine-based immunotherapy regimens |
| KR20160006168A (ko) | 2013-03-18 | 2016-01-18 | 바이오서오엑스 프로덕스 비.브이. | 인간화 항-cd134(ox40) 항체 및 이의 용도 |
| WO2014169462A1 (zh) * | 2013-04-18 | 2014-10-23 | 西安力邦医药科技有限责任公司 | 具有抗癌活性的7-α-[9-(4,4,5,5,-五氟戊基亚硫酰基)壬基]-雌甾-1,3,5(10)-三烯-3,17β-二醇的酯类衍生物及其制备方法 |
| WO2019036855A1 (en) | 2017-08-21 | 2019-02-28 | Adagene Inc. | Anti-cd137 molecules and use thereof |
| WO2019148445A1 (en) | 2018-02-02 | 2019-08-08 | Adagene Inc. | Precision/context-dependent activatable antibodies, and methods of making and using the same |
| WO2019148444A1 (en) | 2018-02-02 | 2019-08-08 | Adagene Inc. | Anti-ctla4 antibodies and methods of making and using the same |
| WO2021228178A1 (en) | 2020-05-13 | 2021-11-18 | Adagene Ag | Compositions and methods for treating cancer |
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| BR0113625A (pt) * | 2000-09-08 | 2003-07-22 | Pharmacia Italia Spa | Exemestano como agente de quimioprevenção |
| WO2002072106A2 (en) | 2001-01-26 | 2002-09-19 | Pharmacia Italia Spa | Combined method for treating hormono-dependent disorders with exemestane |
| US8088737B2 (en) * | 2003-04-04 | 2012-01-03 | Incyte Corporation | Compositions, methods and kits relating to Her-2 cleavage |
| WO2004096139A2 (en) * | 2003-04-24 | 2004-11-11 | Incyte Corporation | Aza spiro alkane derivatives as inhibitors of metalloproteases |
| MXPA06004191A (es) | 2003-10-17 | 2007-01-19 | Incyte Corp | Hidroxamatos ciclicos sustituidos en la forma inhibidores de metaloproteinasas de matriz. |
| WO2005117882A2 (en) | 2004-04-20 | 2005-12-15 | Incyte Corporation | Hydroxamic acid derivatives as metalloprotease inhibitors |
| WO2007143600A2 (en) * | 2006-06-05 | 2007-12-13 | Incyte Corporation | Sheddase inhibitors combined with cd30-binding immunotherapeutics for the treatment of cd30 positive diseases |
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| WO2007062093A3 (en) | 2008-10-23 |
| JP2009516747A (ja) | 2009-04-23 |
| US8324194B2 (en) | 2012-12-04 |
| US20070117809A1 (en) | 2007-05-24 |
| EP1951242A2 (en) | 2008-08-06 |
| WO2007062093A2 (en) | 2007-05-31 |
| CA2628747C (en) | 2014-01-21 |
| CA2628747A1 (en) | 2007-05-31 |
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