JP5249484B2 - 医薬組成物 - Google Patents

医薬組成物 Download PDF

Info

Publication number
JP5249484B2
JP5249484B2 JP2002356114A JP2002356114A JP5249484B2 JP 5249484 B2 JP5249484 B2 JP 5249484B2 JP 2002356114 A JP2002356114 A JP 2002356114A JP 2002356114 A JP2002356114 A JP 2002356114A JP 5249484 B2 JP5249484 B2 JP 5249484B2
Authority
JP
Japan
Prior art keywords
compound
methyl
acid
phenoxy
benzimidazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2002356114A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003238406A (ja
JP2003238406A5 (https=
Inventor
智之 柴田
慎一 蔵方
尚美 島崎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Priority to JP2002356114A priority Critical patent/JP5249484B2/ja
Publication of JP2003238406A publication Critical patent/JP2003238406A/ja
Publication of JP2003238406A5 publication Critical patent/JP2003238406A5/ja
Application granted granted Critical
Publication of JP5249484B2 publication Critical patent/JP5249484B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2002356114A 2001-12-11 2002-12-09 医薬組成物 Expired - Fee Related JP5249484B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2002356114A JP5249484B2 (ja) 2001-12-11 2002-12-09 医薬組成物

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001-376954 2001-12-11
JP2001376954 2001-12-11
JP2001376954 2001-12-11
JP2002356114A JP5249484B2 (ja) 2001-12-11 2002-12-09 医薬組成物

Publications (3)

Publication Number Publication Date
JP2003238406A JP2003238406A (ja) 2003-08-27
JP2003238406A5 JP2003238406A5 (https=) 2006-03-30
JP5249484B2 true JP5249484B2 (ja) 2013-07-31

Family

ID=27790693

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002356114A Expired - Fee Related JP5249484B2 (ja) 2001-12-11 2002-12-09 医薬組成物

Country Status (1)

Country Link
JP (1) JP5249484B2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4789180B2 (ja) * 2004-09-28 2011-10-12 第一三共株式会社 ６−置換−１−メチル−１−ｈ−ベンズイミダゾール誘導体の製造方法及びその製造中間体
WO2006035685A1 (ja) 2004-09-28 2006-04-06 Sankyo Company, Limited ６－置換－１－メチル－１－ｈ－ベンズイミダゾール誘導体の製造方法及びその製造中間体
JP5133071B2 (ja) * 2006-02-09 2013-01-30 第一三共株式会社 抗癌医薬組成物
TW200838512A (en) * 2007-02-08 2008-10-01 Daiichi Sankyo Co Ltd Crystalline forms of a thiazolidinedione compound and manufacturing methods thereof
TW201008936A (en) 2008-07-31 2010-03-01 Daiichi Sankyo Co Ltd Crystalline forms of thiazolidinedione compound and its manufacturing method
WO2010013768A1 (ja) 2008-07-31 2010-02-04 第一三共株式会社 チアゾリジンジオン化合物の結晶及びその製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ282548B6 (cs) * 1992-01-22 1997-08-13 F. Hoffmann-La Roche Ag Farmaceutický přípravek
ATE187434T1 (de) * 1993-01-11 1999-12-15 Ligand Pharm Inc Selektivitaet fuer retinoid x rezeptoren enthaltende verbindungen
JPH08511027A (ja) * 1993-01-11 1996-11-19 リガンド・ファーマシューティカルズ・インコーポレーテッド レチノイドｘレセプターに対して選択的な活性を有する化合物、およびレチノイドｘレセプターによって媒体されたプロセスの調節手段
CA2233888A1 (en) * 1995-10-06 1997-04-10 Ligand Pharmaceuticals Incorporated Dimer-selective rxr modulators and methods for their use
EP1410799B1 (en) * 1996-12-11 2010-03-31 Dana-Farber Cancer Institute, Inc. Methods and pharmaceutical compositions for inhibiting tumour cell growth
AU5811298A (en) * 1996-12-31 1998-07-31 Salk Institute For Biological Studies, The Treatment of disease states which result from neoplastic cell proliferation using ppar-gamma activators and compositions useful therefor
WO1998032444A1 (en) * 1997-01-24 1998-07-30 The Regents Of The University Of California USE OF FXR, PPARα AND LXRα ACTIVATORS TO RESTORE BARRIER FUNCTION, PROMOTE EPIDERMAL DIFFERENTIATION AND INHIBIT PROLIFERATION
JP3488099B2 (ja) * 1997-10-08 2004-01-19 三共株式会社 置換縮合複素環化合物
CA2366281A1 (en) * 1999-03-11 2000-09-14 Nuclear Receptor Research Limited Novel ligands of nuclear receptors ppar's
JP4197387B2 (ja) * 1999-04-07 2008-12-17 第一三共株式会社 アミン誘導体化合物
JP4169450B2 (ja) * 1999-04-07 2008-10-22 第一三共株式会社 インスリン抵抗性改善剤
JP2002542268A (ja) * 1999-04-23 2002-12-10 ブリストル−マイヤーズ スクイブ カンパニー 過増殖性疾患の処置組成物および方法

Also Published As

Publication number Publication date
JP2003238406A (ja) 2003-08-27

Similar Documents

Publication Publication Date Title
US8987461B2 (en) Histone demethylase inhibitors
US9023882B2 (en) 5-membered nitrogen containing heterocyclic derivatives and pharmaceutical compositions comprising the same
WO1992009279A1 (fr) Derive de 2-arylthiazole et composition pharmaceutique contenant ce derive
CA2646430A1 (en) Bicyclic carboxylic acid derivatives useful for treating metabolic disorders
GB2210368A (en) 2-aryl substituted heterocyclic compounds as antiallergic and anti-inflammatory agents
JP2007015928A (ja) 新規オレフィン誘導体
HUT76637A (en) Bezoxazoles and pyridine derivatives, pharmaceutical compositions containing them, process for producing them and their use and the intermediates of the compounds
EP1745029A1 (en) Substituted morpholine compounds for the treatment of central nervous system disorders
CN110357789B (zh) 作为dhodh抑制剂的n-取代丙烯酰胺衍生物及其制备和用途
EP4380928B1 (en) Pparg inverse agonists and uses thereof
JPWO2002076918A1 (ja) 置換安息香酸誘導体を有効成分とするＮＦ−κＢ阻害剤
US8263622B2 (en) Fused-ring derivative and medical application of same
EP2505198A1 (en) Compounds for use as therapeutic agents affecting p53 expression and/or activity
KR102002446B1 (ko) TGase 2 억제제로서의 퀴놀린-5,8-디온 유도체 및 이를 포함하는 약제학적 조성물
Munikrishnappa et al. Design, synthesis, and biological evaluation of novel bromo-pyrimidine analogues as tyrosine kinase inhibitors
JP5249484B2 (ja) 医薬組成物
WO2008087514A2 (en) Hdac inhibitors
US7759350B2 (en) Pyrimidine carboxamides
CN101243073A (zh) 5－ht1a受体的哌嗪－哌啶拮抗剂与激动剂
WO2008025526A1 (en) Indole derivatives, their manufacture and use as pharmaceutical agents
CN117580831A (zh) Grk2抑制剂及其用途
JP6758374B2 (ja) Ｉｄｈ２突然変異を標的とする抗腫瘍化合物及びその使用方法
US8263044B2 (en) Stilbene like compounds as novel HDAC inhibitors
WO2006070878A1 (ja) カルボン酸誘導体またはその塩
JP2017206444A (ja) 置換フェニル化合物

Legal Events

Date Code Title Description
RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20040816

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20050517

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20050602

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20051209

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060210

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090728

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090918

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20090918

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100305

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100422

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100901

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20130412

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20160419

Year of fee payment: 3

LAPS Cancellation because of no payment of annual fees