JP5191237B2 - ビタミンｂ１の前駆体の製造方法 - Google Patents

ビタミンｂ１の前駆体の製造方法 Download PDF

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Publication number
JP5191237B2
JP5191237B2 JP2007552562A JP2007552562A JP5191237B2 JP 5191237 B2 JP5191237 B2 JP 5191237B2 JP 2007552562 A JP2007552562 A JP 2007552562A JP 2007552562 A JP2007552562 A JP 2007552562A JP 5191237 B2 JP5191237 B2 JP 5191237B2
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JP
Japan
Prior art keywords
gda
compound
formula
diamine
analyzed
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Expired - Fee Related
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JP2007552562A
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English (en)
Japanese (ja)
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JP2008528529A5 (enExample
JP2008528529A (ja
Inventor
ワーナー ボンラス，
ジョセリン フィシュケッサー，
リサ ジラウディ，
レインハルド カルゲ，
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DSM IP Assets BV
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DSM IP Assets BV
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Expired - Fee Related legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2007552562A 2005-01-28 2006-01-24 ビタミンｂ１の前駆体の製造方法 Expired - Fee Related JP5191237B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05001859.7 2005-01-28
EP05001859 2005-01-28
PCT/EP2006/000600 WO2006079504A2 (en) 2005-01-28 2006-01-24 Process for the manufacture of a precursor of vitamin b1

Publications (3)

Publication Number Publication Date
JP2008528529A JP2008528529A (ja) 2008-07-31
JP2008528529A5 JP2008528529A5 (enExample) 2012-10-04
JP5191237B2 true JP5191237B2 (ja) 2013-05-08

Family

ID=36118080

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007552562A Expired - Fee Related JP5191237B2 (ja) 2005-01-28 2006-01-24 ビタミンｂ１の前駆体の製造方法

Country Status (9)

Country Link
US (1) US9108925B2 (enExample)
EP (1) EP1841745B1 (enExample)
JP (1) JP5191237B2 (enExample)
KR (1) KR101277352B1 (enExample)
CN (1) CN101111484B (enExample)
AT (1) ATE397593T1 (enExample)
DE (1) DE602006001394D1 (enExample)
ES (1) ES2308715T3 (enExample)
WO (1) WO2006079504A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101627017B (zh) * 2006-03-15 2013-02-27 帝斯曼知识产权资产管理有限公司 用于制造维生素b1前体的方法
JP5618306B2 (ja) * 2008-07-22 2014-11-05 ディーエスエム アイピー アセッツ ビー．ブイ． 置換４−アミノ−ピリミジンの新規合成
CN103896935B (zh) * 2012-12-27 2016-08-10 江西天新药业有限公司 3-[(4-氨基-5-嘧啶基)甲基]-5-(2-羟乙基)-4-甲基噻唑硝酸盐的制备方法
CN104326989B (zh) * 2014-11-26 2016-04-27 江西天新药业有限公司 2-甲基-4-氨基-5-(氨基甲基)嘧啶的制备方法
US9682216B2 (en) 2014-12-05 2017-06-20 Anchor Endovascular, Inc. Anchor device for use with catheters
CN108546249B (zh) * 2018-02-28 2021-10-01 东北制药集团股份有限公司 一种制备双胺嘧啶的方法
CN109467553B (zh) * 2018-12-24 2021-02-12 江苏兄弟维生素有限公司 一种甲酰嘧啶的提纯方法以及维生素b1合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2775592A (en) * 1956-12-25 Z-methyl -
EP0001760B1 (de) * 1977-10-27 1981-01-07 BASF Aktiengesellschaft Alpha-aminomethylen-beta-formylaminopropionitril, Verfahren zu seiner Herstellung sowie Verwendung zur Herstellung von 2-Methyl-4-amino-5-formylaminomethyl-pyrimidin
JPS5576084A (en) * 1978-12-01 1980-06-07 Takeda Chem Ind Ltd Method and apparatus for production of vitamin b1 and intermediate thereof
DE3511273A1 (de) * 1985-03-28 1986-10-09 Basf Ag, 6700 Ludwigshafen Verbessertes verfahren zur herstellung von 2-methyl-4-amino-5-aminomethyl-pyrimidin
DE10015470A1 (de) * 2000-03-29 2001-10-11 Basf Ag Verfahren zur Herstellung von 2-Methyl-4-amino-5-aminomethyrimidin

Also Published As

Publication number Publication date
US9108925B2 (en) 2015-08-18
DE602006001394D1 (de) 2008-07-17
CN101111484B (zh) 2013-07-24
CN101111484A (zh) 2008-01-23
KR20070098888A (ko) 2007-10-05
WO2006079504A3 (en) 2007-02-15
ATE397593T1 (de) 2008-06-15
ES2308715T3 (es) 2008-12-01
EP1841745B1 (en) 2008-06-04
US20080242863A1 (en) 2008-10-02
JP2008528529A (ja) 2008-07-31
KR101277352B1 (ko) 2013-06-20
EP1841745A2 (en) 2007-10-10
WO2006079504A2 (en) 2006-08-03

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