JP5164306B2 - マイクロ流体スイッチ - Google Patents
マイクロ流体スイッチ Download PDFInfo
- Publication number
- JP5164306B2 JP5164306B2 JP2004016395A JP2004016395A JP5164306B2 JP 5164306 B2 JP5164306 B2 JP 5164306B2 JP 2004016395 A JP2004016395 A JP 2004016395A JP 2004016395 A JP2004016395 A JP 2004016395A JP 5164306 B2 JP5164306 B2 JP 5164306B2
- Authority
- JP
- Japan
- Prior art keywords
- flow path
- fluid
- end region
- flow
- common end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000012530 fluid Substances 0.000 title claims description 189
- 239000011796 hollow space material Substances 0.000 claims description 16
- 238000004458 analytical method Methods 0.000 claims description 12
- 239000003153 chemical reaction reagent Substances 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 8
- 230000007704 transition Effects 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
- 238000009736 wetting Methods 0.000 claims description 4
- 238000006243 chemical reaction Methods 0.000 description 14
- 230000008859 change Effects 0.000 description 4
- 230000009471 action Effects 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 230000005499 meniscus Effects 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
Images
Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
- F16K99/0017—Capillary or surface tension valves, e.g. using electro-wetting or electro-capillarity effects
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
- F16K99/0028—Valves having multiple inlets or outlets
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0034—Operating means specially adapted for microvalves
- F16K99/0055—Operating means specially adapted for microvalves actuated by fluids
- F16K99/0057—Operating means specially adapted for microvalves actuated by fluids the fluid being the circulating fluid itself, e.g. check valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0621—Control of the sequence of chambers filled or emptied
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0082—Microvalves adapted for a particular use
- F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/2076—Utilizing diverse fluids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/218—Means to regulate or vary operation of device
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/2224—Structure of body of device
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Micromachines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10302720.3 | 2003-01-23 | ||
| DE2003102720 DE10302720A1 (de) | 2003-01-23 | 2003-01-23 | Mikrofluidischer Schalter zum Anhalten des Flüssigkeitsstroms während eines Zeitintervalls |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004225912A JP2004225912A (ja) | 2004-08-12 |
| JP2004225912A5 JP2004225912A5 (enExample) | 2007-04-19 |
| JP5164306B2 true JP5164306B2 (ja) | 2013-03-21 |
Family
ID=32520085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004016395A Expired - Fee Related JP5164306B2 (ja) | 2003-01-23 | 2004-01-23 | マイクロ流体スイッチ |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7134453B2 (enExample) |
| EP (1) | EP1441131B1 (enExample) |
| JP (1) | JP5164306B2 (enExample) |
| CN (1) | CN100531915C (enExample) |
| DE (1) | DE10302720A1 (enExample) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7148257B2 (en) * | 2002-03-04 | 2006-12-12 | Merck Hdac Research, Llc | Methods of treating mesothelioma with suberoylanilide hydroxamic acid |
| US7407630B2 (en) | 2003-09-19 | 2008-08-05 | Applera Corporation | High density plate filler |
| US8277760B2 (en) | 2003-09-19 | 2012-10-02 | Applied Biosystems, Llc | High density plate filler |
| US20070014694A1 (en) * | 2003-09-19 | 2007-01-18 | Beard Nigel P | High density plate filler |
| US20050232821A1 (en) * | 2003-09-19 | 2005-10-20 | Carrillo Albert L | High density plate filler |
| US7998435B2 (en) | 2003-09-19 | 2011-08-16 | Life Technologies Corporation | High density plate filler |
| EP1525916A1 (en) * | 2003-10-23 | 2005-04-27 | F. Hoffmann-La Roche Ag | Flow triggering device |
| EP1525919A1 (en) * | 2003-10-23 | 2005-04-27 | F. Hoffmann-La Roche Ag | Flow triggering device |
| GB0327094D0 (en) * | 2003-11-21 | 2003-12-24 | Inverness Medical Switzerland | Laminated device |
| DE102004007567A1 (de) * | 2004-02-17 | 2005-09-01 | Boehringer Ingelheim Microparts Gmbh | Mikrostrukturierte Plattform und Verfahren zum Handhaben einer Flüssigkeit |
| WO2006061026A2 (en) * | 2004-12-09 | 2006-06-15 | Inverness Medical Switzerland Gmbh | A micro fluidic device and methods for producing a micro fluidic device |
| EP1843849A2 (en) * | 2005-01-12 | 2007-10-17 | Inverness Medical Switzerland GmbH | A method of producing a microfluidic device and microfluidic devices |
| ES2361169T3 (es) * | 2005-01-27 | 2011-06-14 | Boehringer Ingelheim Microparts Gmbh | Uso de un dispositivo para el análisis de muestras de líquido. |
| EP1853911A1 (en) * | 2005-02-25 | 2007-11-14 | Inverness Medical Switzerland GmbH | Fluidic gating device |
| DE102005016509A1 (de) * | 2005-04-09 | 2006-10-12 | Boehringer Ingelheim Microparts Gmbh | Vorrichtung und Verfahren zur Untersuchung einer Probenflüssigkeit |
| DE102005042601A1 (de) * | 2005-04-09 | 2006-10-12 | Boehringer Ingelheim Microparts Gmbh | Vorrichtung und Verfahren zur Untersuchung einer Probenflüssigkeit |
| WO2006108559A2 (de) * | 2005-04-09 | 2006-10-19 | Boehringer Ingelheim Microparts Gmbh | Vorrichtung und verfahren zur untersuchung einer probenflüssigkeit |
| DE102005016508A1 (de) * | 2005-04-09 | 2006-10-12 | Boehringer Ingelheim Microparts Gmbh | Vorrichtung und Verfahren zur Untersuchung einer Probenflüssigkeit |
| DE102005017653A1 (de) | 2005-04-15 | 2006-10-19 | Boehringer Ingelheim Microparts Gmbh | Vorrichtung und Verfahren zur Manipulation einer Flüssigkeit |
| WO2007006315A2 (en) * | 2005-07-07 | 2007-01-18 | Inverness Medical Switzerland Gmbh | A method of performing a test, a support instrument and a microliquid system comprising such support instrument |
| US7731910B2 (en) * | 2005-08-05 | 2010-06-08 | Hewlett-Packard Development Company, L.P. | Microfluidic mixing assembly |
| US20070113907A1 (en) * | 2005-11-18 | 2007-05-24 | Reid Brennen | Devices and methods using fluid-transporting features of differing dwell times |
| CN101400432B (zh) * | 2006-03-09 | 2012-02-15 | 积水化学工业株式会社 | 微量流体设备及微量液体稀释方法 |
| CN101173887B (zh) * | 2006-11-02 | 2011-04-06 | 深圳迈瑞生物医疗电子股份有限公司 | 鞘流阻抗法粒子分析仪 |
| JP4852399B2 (ja) | 2006-11-22 | 2012-01-11 | 富士フイルム株式会社 | 二液合流装置 |
| US8877484B2 (en) * | 2007-01-10 | 2014-11-04 | Scandinavian Micro Biodevices Aps | Microfluidic device and a microfluidic system and a method of performing a test |
| WO2008113112A1 (en) * | 2007-03-16 | 2008-09-25 | Cleveland Biosensors Pty Ltd | Stop structure for microfluidic device |
| SE0700930L (sv) * | 2007-04-16 | 2008-01-22 | Aamic Ab | Analysanordning för vätskeformiga prov |
| SE533515C2 (sv) | 2008-04-16 | 2010-10-12 | Aamic Ab | Analysförfarande för samtidig analys av flera analyter |
| US8063236B2 (en) * | 2008-05-08 | 2011-11-22 | University Of Florida Research Foundation, Inc. | Method for transferring N-atoms from metal complexes to organic and inorganic substrates |
| WO2010012281A1 (en) | 2008-07-29 | 2010-02-04 | Jacques Jonsmann | A microfluidic device |
| EP2451575A2 (en) * | 2009-07-07 | 2012-05-16 | Boehringer Ingelheim Microparts GmbH | Plasma separation reservoir |
| ATE542136T1 (de) | 2010-03-15 | 2012-02-15 | Boehringer Ingelheim Int | Vorrichtung und verfahren zur manipulation oder untersuchung einer flüssigen probe |
| US9364807B2 (en) | 2010-03-31 | 2016-06-14 | Boehringer Ingelheim Microparts Gmbh | Component of a biosensor and process for production |
| WO2012034270A1 (zh) * | 2010-09-14 | 2012-03-22 | Peng Xingyue | 一种微流路芯片系列微器件的结构 |
| EP2625531B1 (en) | 2010-10-08 | 2018-12-12 | Biomerieux, Inc | Improved sample test cards |
| JP5907979B2 (ja) * | 2010-10-28 | 2016-04-26 | インターナショナル・ビジネス・マシーンズ・コーポレーションInternational Business Machines Corporation | 補助チャネルおよびバイパス・チャネルを含むマイクロ流体デバイス |
| EP2486978A1 (de) | 2010-10-28 | 2012-08-15 | Roche Diagnostics GmbH | Mikrofluidischer Testträger zum Aufteilen einer Flüssigkeitsmenge in Teilmengen |
| EP2455162A1 (de) * | 2010-10-29 | 2012-05-23 | Roche Diagnostics GmbH | Mikrofluidisches Element zur Analyse einer Probenflüssigkeit |
| WO2012071437A1 (en) | 2010-11-23 | 2012-05-31 | Biomerieux, Inc. | Improved sample test cards |
| DE102011078770B4 (de) * | 2011-07-07 | 2016-04-28 | Robert Bosch Gmbh | Mikrofluidische Vorrichtung, mikrofluidisches System und Verfahren zum Transport von Fluiden |
| US9822890B2 (en) | 2011-08-30 | 2017-11-21 | The Royal Institution For The Advancement Of Learning/Mcgill University | Method and system for pre-programmed self-power microfluidic circuits |
| JP6162716B2 (ja) | 2011-12-14 | 2017-07-12 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 対象周波数多重経路長ミキサ |
| ITUD20120028A1 (it) * | 2012-02-21 | 2013-08-22 | Sedicidodici S R L | Camera di perfusione, relativa apparecchiatura utilizzante tale camera di perfusione e procedimento per l'analisi della patologia trombotico-ischemica ed emorragica |
| PL398979A1 (pl) * | 2012-04-25 | 2013-10-28 | Scope Fluidics Spólka Z Ograniczona Odpowiedzialnoscia | Urzadzenie mikroprzeplywowe i uklad mikroprzeplywowy obejmujacy jedno lub wiecej urzadzen mikroprzeplywowych |
| EP3584010A1 (de) | 2012-07-30 | 2019-12-25 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen | Untersuchungsverfahren an und/oder mit einem biologischen probenmaterial |
| US9138746B2 (en) | 2013-05-01 | 2015-09-22 | Honeywell International Inc. | Fluid stop for measured sample containment |
| EP3154691B1 (en) | 2014-06-16 | 2022-06-29 | Siemens Healthineers Nederland B.V. | Cartridge for fast sample intake |
| US10875017B2 (en) | 2015-01-23 | 2020-12-29 | Neofluidics Llc | Microfluidic serial dilution platform based well-plate using an oil-free immiscible phase driven by manual or electronic pipettors |
| US12290811B2 (en) | 2015-01-23 | 2025-05-06 | Unchained Labs | Microfluidic serial dilution platform based well-plate using an oil-free immiscible phase driven by manual or electronic pipettors |
| DE102015204235B4 (de) * | 2015-03-10 | 2016-12-15 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Fluidikstruktur mit Halteabschnitt und Verfahren zum Vereinigen zweier Flüssigkeitsvolumina |
| KR102021102B1 (ko) | 2015-04-03 | 2019-09-11 | 내셔날 인스티튜트 오브 어드밴스드 인더스트리얼 사이언스 앤드 테크놀로지 | 세포 배양 장치 및 세포 배양 방법 |
| US10981166B2 (en) | 2015-06-11 | 2021-04-20 | Neofluidics Llc | Manual or electronic pipette driven well plate for nano-liter droplet storage and methods of using same |
| US10537862B2 (en) * | 2015-06-29 | 2020-01-21 | Imec Vzw | Valve-less mixing method and mixing device |
| WO2018200896A1 (en) * | 2017-04-28 | 2018-11-01 | Neofluidics, Llc | Fluidic devices with reaction wells and uses thereof |
| EP3622777B1 (en) | 2017-05-12 | 2021-07-07 | Telefonaktiebolaget LM Ericsson (Publ) | Local identifier locator network protocol (ilnp) breakout |
| US11441701B2 (en) | 2017-07-14 | 2022-09-13 | Hewlett-Packard Development Company, L.P. | Microfluidic valve |
| EP3665262A4 (en) | 2017-08-09 | 2021-09-01 | Neofluidics, LLC | DEVICES AND METHODS FOR BIOLOGICAL TESTING |
| US11185830B2 (en) | 2017-09-06 | 2021-11-30 | Waters Technologies Corporation | Fluid mixer |
| US11305279B2 (en) | 2017-11-10 | 2022-04-19 | Neofluidics, Llc | Integrated fluidic circuit and device for droplet manipulation and methods thereof |
| WO2019240764A1 (en) | 2018-06-11 | 2019-12-19 | Hewlett-Packard Development Company, L.P. | Microfluidic valves |
| WO2020023942A2 (en) * | 2018-07-27 | 2020-01-30 | Terumo Bct Biotechnologies, Llc | Fluid flow-through |
| EP3870369A4 (en) * | 2018-10-26 | 2022-11-09 | Neofluidics, LLC | FLUID DEVICES HAVING REACTION WELLS AND THROAT CHANNEL AND USES THEREOF |
| WO2020096594A1 (en) | 2018-11-07 | 2020-05-14 | Telefonaktiebolaget Lm Ericsson (Publ) | Local identifier locator network protocol (ilnp) breakout |
| US11405752B2 (en) | 2019-05-16 | 2022-08-02 | Arris Enterprises Llc | Automated frequency coordination and device location awareness |
| CN114207433B (zh) | 2019-08-12 | 2025-01-14 | 沃特世科技公司 | 用于色谱系统的混合器 |
| EP3822634B1 (en) * | 2019-11-14 | 2025-09-24 | Apex Biotechnology Corporation | Biosensor strip |
| EP4103324A4 (en) * | 2020-02-12 | 2024-01-17 | University of Canterbury | Microfluidic sealing valve and microfluidic circuit |
| JP7665636B2 (ja) * | 2020-02-19 | 2025-04-21 | ミダイアグノスティクス・エヌブイ | 所定のサンプル体積を有するサンプル流体を提供するためのマイクロ流体システムおよび方法 |
| WO2021252852A1 (en) * | 2020-06-11 | 2021-12-16 | The Research Foundation For The State University Of New York | Microfluidic device and method |
| CN116194767A (zh) | 2020-09-22 | 2023-05-30 | 沃特世科技公司 | 连续流混合器 |
| CN113117768A (zh) * | 2021-04-09 | 2021-07-16 | 四川微康朴澜医疗科技有限责任公司 | 一种微流控芯片流道切换与试剂切换的集成 |
| AU2022331216A1 (en) * | 2021-08-18 | 2024-03-14 | University Of Canterbury | Microfluidic devices, systems and methods for providing an indication of rheology of a substance |
| US12404951B1 (en) * | 2022-03-07 | 2025-09-02 | United States Of America As Represented By The Administrator Of Nasa | Microfluidics pressure-based switching and valving array |
| EP4519017A1 (en) * | 2022-05-02 | 2025-03-12 | Katholieke Universiteit Leuven | Dilution device |
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| WO1999046045A1 (de) * | 1998-03-11 | 1999-09-16 | MICROPARTS GESELLSCHAFT FüR MIKROSTRUKTURTECHNIK MBH | Probenträger |
| US6601613B2 (en) * | 1998-10-13 | 2003-08-05 | Biomicro Systems, Inc. | Fluid circuit components based upon passive fluid dynamics |
| WO2000022436A1 (en) * | 1998-10-13 | 2000-04-20 | Biomicro Systems, Inc. | Fluid circuit components based upon passive fluid dynamics |
| DE19859693A1 (de) * | 1998-12-23 | 2000-06-29 | Microparts Gmbh | Vorrichtung zum Ableiten einer Flüssigkeit aus Kapillaren |
| US6615856B2 (en) * | 2000-08-04 | 2003-09-09 | Biomicro Systems, Inc. | Remote valving for microfluidic flow control |
| WO2002011888A2 (en) * | 2000-08-07 | 2002-02-14 | Nanostream, Inc. | Fluidic mixer in microfluidic system |
| CA2422550A1 (en) * | 2000-09-22 | 2003-03-18 | Atsushi Teramae | Very small chemical device and flow rate adjusting method therefor |
| WO2002086333A1 (en) * | 2001-04-25 | 2002-10-31 | President And Fellows Of Harvard College | Fluidic switches and method for controlling flow in fluidic systems |
| US6725882B1 (en) * | 2003-01-03 | 2004-04-27 | Industrial Technology Research Institute | Configurable micro flowguide device |
-
2003
- 2003-01-23 DE DE2003102720 patent/DE10302720A1/de not_active Ceased
-
2004
- 2004-01-20 EP EP04001098.5A patent/EP1441131B1/de not_active Expired - Lifetime
- 2004-01-20 CN CNB2004100077974A patent/CN100531915C/zh not_active Expired - Fee Related
- 2004-01-23 US US10/762,564 patent/US7134453B2/en not_active Expired - Lifetime
- 2004-01-23 JP JP2004016395A patent/JP5164306B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1441131A1 (de) | 2004-07-28 |
| DE10302720A1 (de) | 2004-08-05 |
| CN100531915C (zh) | 2009-08-26 |
| JP2004225912A (ja) | 2004-08-12 |
| CN1526479A (zh) | 2004-09-08 |
| US20040206408A1 (en) | 2004-10-21 |
| US7134453B2 (en) | 2006-11-14 |
| EP1441131B1 (de) | 2017-12-20 |
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