JP5142981B2 - 抗ｅｇｆｒ抗体およびｖｅｇｆｒ阻害剤を含む、癌の治療のための組み合わせ - Google Patents

抗ｅｇｆｒ抗体およびｖｅｇｆｒ阻害剤を含む、癌の治療のための組み合わせ Download PDF

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JP5142981B2
JP5142981B2 JP2008503187A JP2008503187A JP5142981B2 JP 5142981 B2 JP5142981 B2 JP 5142981B2 JP 2008503187 A JP2008503187 A JP 2008503187A JP 2008503187 A JP2008503187 A JP 2008503187A JP 5142981 B2 JP5142981 B2 JP 5142981B2
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cancer
acid
vegf
inhibitors
tumor
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JP2009515814A5 (https=
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チヤン，デイビツド
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アムジエン・インコーポレーテツド
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
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    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
JP2008503187A 2005-03-22 2006-03-22 抗ｅｇｆｒ抗体およびｖｅｇｆｒ阻害剤を含む、癌の治療のための組み合わせ Expired - Fee Related JP5142981B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66438105P 2005-03-22 2005-03-22
US60/664,381 2005-03-22
US11/386,271 2006-03-21
US11/386,271 US20060216288A1 (en) 2005-03-22 2006-03-21 Combinations for the treatment of cancer
PCT/US2006/010582 WO2006102504A2 (en) 2005-03-22 2006-03-22 Combinations for the treatment of cancer comprising anti-egfr antibody and vegfr inhibitors

Publications (3)

Publication Number Publication Date
JP2009515814A JP2009515814A (ja) 2009-04-16
JP2009515814A5 JP2009515814A5 (https=) 2009-05-28
JP5142981B2 true JP5142981B2 (ja) 2013-02-13

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JP2008503187A Expired - Fee Related JP5142981B2 (ja) 2005-03-22 2006-03-22 抗ｅｇｆｒ抗体およびｖｅｇｆｒ阻害剤を含む、癌の治療のための組み合わせ

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US (2) US20060216288A1 (https=)
EP (1) EP1915151B1 (https=)
JP (1) JP5142981B2 (https=)
AU (1) AU2006226897B2 (https=)
CA (1) CA2600195C (https=)
MX (1) MX2007011545A (https=)
WO (1) WO2006102504A2 (https=)

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Also Published As

Publication number Publication date
EP1915151A2 (en) 2008-04-30
US20060216288A1 (en) 2006-09-28
JP2009515814A (ja) 2009-04-16
WO2006102504A2 (en) 2006-09-28
CA2600195A1 (en) 2006-09-28
US20100074909A1 (en) 2010-03-25
AU2006226897B2 (en) 2009-05-07
EP1915151B1 (en) 2011-08-17
AU2006226897A1 (en) 2006-09-28
CA2600195C (en) 2012-10-16
WO2006102504A3 (en) 2006-12-07
MX2007011545A (es) 2008-03-11

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