JP5127138B2 - 前立腺及び他の癌の治療用の組成物及び方法 - Google Patents

前立腺及び他の癌の治療用の組成物及び方法 Download PDF

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JP5127138B2
JP5127138B2 JP2005500014A JP2005500014A JP5127138B2 JP 5127138 B2 JP5127138 B2 JP 5127138B2 JP 2005500014 A JP2005500014 A JP 2005500014A JP 2005500014 A JP2005500014 A JP 2005500014A JP 5127138 B2 JP5127138 B2 JP 5127138B2
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cancer
hsp27
antisense
rnai
hsp
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JP2006503904A (ja
JP2006503904A5 (enExample
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グリーブ、マーティン、イー．
ロッキ、パルマ
シグナエブスキー、マクシム
ベラルディ、エリアナ
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ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61P35/00—Antineoplastic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2005500014A 2002-10-02 2003-10-02 前立腺及び他の癌の治療用の組成物及び方法 Expired - Fee Related JP5127138B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41585902P 2002-10-02 2002-10-02
US60/415,859 2002-10-02
US46395203P 2003-04-18 2003-04-18
US60/463,952 2003-04-18
PCT/CA2003/001588 WO2004030660A2 (en) 2002-10-02 2003-10-02 Compositions for treatment of prostate and other cancers

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JP2010155315A Division JP5237996B2 (ja) 2002-10-02 2010-07-08 前立腺及び他の癌の治療用の組成物及び方法

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JP2006503904A JP2006503904A (ja) 2006-02-02
JP2006503904A5 JP2006503904A5 (enExample) 2006-09-28
JP5127138B2 true JP5127138B2 (ja) 2013-01-23

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JP2005500014A Expired - Fee Related JP5127138B2 (ja) 2002-10-02 2003-10-02 前立腺及び他の癌の治療用の組成物及び方法
JP2010155315A Expired - Fee Related JP5237996B2 (ja) 2002-10-02 2010-07-08 前立腺及び他の癌の治療用の組成物及び方法

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US (8) US7101991B2 (enExample)
EP (2) EP1545561B1 (enExample)
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KR (1) KR101142080B1 (enExample)
CN (1) CN1703229B (enExample)
AT (1) ATE465743T1 (enExample)
AU (1) AU2003278028B2 (enExample)
CA (1) CA2498026C (enExample)
DE (1) DE60332363D1 (enExample)
DK (1) DK1545561T3 (enExample)
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IL (1) IL167621A (enExample)
MX (1) MXPA05003551A (enExample)
NO (2) NO338310B1 (enExample)
NZ (1) NZ538841A (enExample)
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US9381209B2 (en) * 2007-03-05 2016-07-05 The University Of British Columbia Treatment of squamous cell carcinoma with HSP27 antisense oligonucleotides and radiotherapy
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DE102010056610A1 (de) * 2010-12-31 2012-07-05 Volker A. Erdmann Pharmazeutische Zusammensetzung enthaltend L-DNA
JP5658696B2 (ja) * 2011-02-25 2015-01-28 株式会社ファンケル 皮膚のストレス蓄積度の評価方法
CA2747509C (en) 2011-05-12 2017-07-18 Oncogenex Technologies Inc. Treatment of pulmonary and pleural fibrosis using hsp27 inhibitors
US9717792B2 (en) 2012-02-02 2017-08-01 The University Of British Columbia Combination therapy for cancer using HSP27 inhibitor and EGFR tyrosine kinase inhibitors or anti-folates
GB201204785D0 (en) 2012-03-19 2012-05-02 Queen Mary & Westfield College Method for determining prognosis of prostate cancer in a subject
KR101374585B1 (ko) * 2012-05-02 2014-03-17 연세대학교 산학협력단 ＨＳＰ２７ 발현을 억제하는 ｓｈＲＮＡ
JP2015529073A (ja) 2012-08-20 2015-10-05 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 生物可逆性基を有するポリヌクレオチド
US20170216297A1 (en) 2014-07-28 2017-08-03 Technische Universitaet Dresden Efficient inhibition of hsp27
WO2017091885A1 (en) 2015-11-30 2017-06-08 The University Of British Columbia Monocarboxylate transporter 4 (mct4) antisense oligonucleotide (aso) inhibitors for use as therapeutics in the treatment of cancer
WO2019050948A1 (en) 2017-09-05 2019-03-14 Regeneron Pharmaceuticals, Inc. ADMINISTRATION OF A GENE EDITION SYSTEM HAVING ONLY ONE RETROVIRAL PARTICLE AND METHODS OF GENERATING AND USING

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US7847091B2 (en) 2010-12-07
US8772470B1 (en) 2014-07-08
US20160326527A1 (en) 2016-11-10
NZ538841A (en) 2006-10-27
EP1545561A2 (en) 2005-06-29
DK1545561T3 (da) 2010-08-02
US20040127441A1 (en) 2004-07-01
IL167621A (en) 2011-11-30
DE60332363D1 (de) 2010-06-10
WO2004030660A3 (en) 2004-06-10
US20060040886A1 (en) 2006-02-23
JP2006503904A (ja) 2006-02-02
NO338310B1 (no) 2016-08-08
US20150232843A1 (en) 2015-08-20
US20090221678A1 (en) 2009-09-03
US7723312B2 (en) 2010-05-25
ATE465743T1 (de) 2010-05-15
WO2004030660A2 (en) 2004-04-15
JP2010215669A (ja) 2010-09-30
US7550580B2 (en) 2009-06-23
AU2003278028A1 (en) 2004-04-23
JP5237996B2 (ja) 2013-07-17
KR101142080B1 (ko) 2012-05-03
EP2216029A3 (en) 2010-12-22
MXPA05003551A (es) 2005-10-19
ZA200502603B (en) 2006-06-28
US20060276424A1 (en) 2006-12-07
ES2345330T3 (es) 2010-09-21
US7101991B2 (en) 2006-09-05
EP2216029A2 (en) 2010-08-11
EP1545561B1 (en) 2010-04-28
US9580712B2 (en) 2017-02-28
AU2003278028B2 (en) 2008-12-18
US20140315978A1 (en) 2014-10-23
NO20160655A1 (no) 2016-04-20
US9085769B2 (en) 2015-07-21
CN1703229A (zh) 2005-11-30
CA2498026C (en) 2015-06-30
NO20052055L (no) 2005-06-23
CN1703229B (zh) 2011-01-05
KR20050050111A (ko) 2005-05-27
CA2498026A1 (en) 2004-04-15
US9404109B2 (en) 2016-08-02

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