JP5089691B2 - 経皮吸収型貼付剤 - Google Patents
経皮吸収型貼付剤 Download PDFInfo
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- JP5089691B2 JP5089691B2 JP2009520377A JP2009520377A JP5089691B2 JP 5089691 B2 JP5089691 B2 JP 5089691B2 JP 2009520377 A JP2009520377 A JP 2009520377A JP 2009520377 A JP2009520377 A JP 2009520377A JP 5089691 B2 JP5089691 B2 JP 5089691B2
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- medicinal component
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- stratum corneum
- protective layer
- living body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/58—Adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
- A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
- A61M35/006—Portable hand-held applicators having means for dispensing or spreading integral media using sponges, foams, absorbent pads or swabs as spreading means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00544—Plasters form or structure
- A61F2013/00646—Medication patches, e.g. transcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/256—Antibodies, e.g. immunoglobulins, vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/428—Vitamins, e.g. tocopherol, riboflavin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
- A61L2300/608—Coatings having two or more layers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/14—Layer or component removable to expose adhesive
- Y10T428/149—Sectional layer removable
- Y10T428/1495—Adhesive is on removable layer
Description
生体表面に貼着して用いられる経皮吸収型貼付剤であって、
シート状の第1の支持基材と、該第1の支持基材の一方の面に積層され、生体表面の古い角質層を除去する機能を有する粘着剤層とで構成された角質層剥離部材と、
前記角質層剥離部材の前記第1の支持基材側に配置され、シート状の第2の支持基材と、該第2の支持基材の前記角質層剥離部材側に積層された薬効成分を含有する薬効成分保持層と、該薬効成分保持層上に積層され、該薬効成分保持層を保護する機能を有するとともに、前記薬効成分保持層から剥離可能な保護層とで構成された薬効成分投与部材と、
前記角質層剥離部材と前記薬効成分投与部材との間に介挿され、生体表面から前記角質層剥離部材を剥離する操作と、前記薬効成分保持層から前記保護層を剥離する操作とを引っ張りにより一括して行うシート状の操作部材とを有し、
前記操作部材は、その操作方向と反対側の縁部において、前記第1の支持基材と前記保護層とに連結または一体化されていることを特徴とする。
Claims (4)
- 生体表面に貼着して用いられる経皮吸収型貼付剤であって、
シート状の第1の支持基材と、該第1の支持基材の一方の面に積層され、生体表面の古い角質層を除去する機能を有する粘着剤層とで構成された角質層剥離部材と、
前記角質層剥離部材の前記第1の支持基材側に配置され、シート状の第2の支持基材と、該第2の支持基材の前記角質層剥離部材側に積層された薬効成分を含有する薬効成分保持層と、該薬効成分保持層上に積層され、該薬効成分保持層を保護する機能を有するとともに、前記薬効成分保持層から剥離可能な保護層とで構成された薬効成分投与部材と、
前記角質層剥離部材と前記薬効成分投与部材との間に介挿され、生体表面から前記角質層剥離部材を剥離する操作と、前記薬効成分保持層から前記保護層を剥離する操作とを引っ張りにより一括して行うシート状の操作部材とを有し、
前記操作部材は、その操作方向と反対側の縁部において、前記第1の支持基材と前記保護層とに連結または一体化されていることを特徴とする経皮吸収型貼付剤。 - 前記操作部材は、2層で構成されたものであり、そのうちの一方の層が前記第1の支持基材と一体的に形成され、他方の層が前記保護層と一体的に形成されたものである請求の範囲第1項に記載の経皮吸収型貼付剤。
- 前記薬効成分保持層は、前記操作部材の前記縁部よりも、前記操作部材の操作方向とは反対側に向かって延在し、前記保護層に覆われていない部分を有している請求の範囲第1項に記載の経皮吸収型貼付剤。
- 前記薬効成分が生物製剤である請求の範囲第1項に記載の経皮吸収型貼付剤。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009520377A JP5089691B2 (ja) | 2007-06-26 | 2008-03-19 | 経皮吸収型貼付剤 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007167294 | 2007-06-26 | ||
JP2007167294 | 2007-06-26 | ||
PCT/JP2008/055108 WO2009001591A1 (ja) | 2007-06-26 | 2008-03-19 | 経皮吸収型貼付剤 |
JP2009520377A JP5089691B2 (ja) | 2007-06-26 | 2008-03-19 | 経皮吸収型貼付剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2009001591A1 JPWO2009001591A1 (ja) | 2010-08-26 |
JP5089691B2 true JP5089691B2 (ja) | 2012-12-05 |
Family
ID=40185415
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009520377A Expired - Fee Related JP5089691B2 (ja) | 2007-06-26 | 2008-03-19 | 経皮吸収型貼付剤 |
Country Status (6)
Country | Link |
---|---|
US (1) | US8071126B2 (ja) |
EP (1) | EP2161050B1 (ja) |
JP (1) | JP5089691B2 (ja) |
KR (1) | KR101463601B1 (ja) |
CA (1) | CA2691596C (ja) |
WO (1) | WO2009001591A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5476062B2 (ja) * | 2008-07-25 | 2014-04-23 | 南部化成株式会社 | 経皮投薬デバイス |
JP2012010966A (ja) * | 2010-06-30 | 2012-01-19 | Lintec Corp | 角質剥離用粘着シート |
EP3233492B1 (en) | 2014-12-18 | 2021-11-10 | Kindeva Drug Delivery L.P. | Methods of handling adhesive laminate patches |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4627429A (en) * | 1986-02-28 | 1986-12-09 | American Home Products Corporation | Storage-stable transdermal adhesive patch |
JPS639546Y2 (ja) * | 1981-09-09 | 1988-03-22 | ||
US20050034732A1 (en) * | 2003-08-13 | 2005-02-17 | Rousseau Robert A. | Surgical wound closure device |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6054284B2 (ja) * | 1981-01-28 | 1985-11-29 | 日東電工株式会社 | 薬物投与部材 |
JPS6054284A (ja) | 1983-09-03 | 1985-03-28 | Hitachi Constr Mach Co Ltd | 溶接スパツタ削除装置 |
JPS639546A (ja) | 1986-07-01 | 1988-01-16 | Canon Inc | インク供給装置 |
GB8721659D0 (en) * | 1987-09-15 | 1987-10-21 | Smith & Nephew Ass | Adhesive coated dressings & applicators |
US4917929A (en) * | 1989-01-18 | 1990-04-17 | Minnesota Mining And Manufacturing Company | One piece adhesive bandage and package unit |
ATE193195T1 (de) * | 1996-02-09 | 2000-06-15 | Coloplast As | Lippe |
US6129929A (en) * | 1998-10-30 | 2000-10-10 | Noven Pharmaceuticals, Inc. | Patch applicator |
US6124522A (en) * | 1998-11-24 | 2000-09-26 | Schroeder; Mark R. | Packaging for adhesive-sided articles to allow one-handed application |
US6140549A (en) * | 1999-01-13 | 2000-10-31 | Pompei, Jr.; John Anthony | Bandage handy strips |
FR2794969B1 (fr) * | 1999-06-16 | 2002-01-18 | Technosphere Sarl | Pansement adhesif |
US7027877B2 (en) * | 2001-08-23 | 2006-04-11 | Zoll Medical Corporation | Method of applying defibrilator electrode pad with folded release sheet |
US6945952B2 (en) * | 2002-06-25 | 2005-09-20 | Theraject, Inc. | Solid solution perforator for drug delivery and other applications |
US7383084B2 (en) * | 2002-10-31 | 2008-06-03 | Transpharma Medical Ltd. | Transdermal delivery system for dried particulate or lyophilized medications |
JP2007510445A (ja) | 2003-10-24 | 2007-04-26 | アルザ・コーポレーシヨン | 経皮薬剤送達促進用の前処置法及びシステム |
JP2005200391A (ja) | 2004-01-14 | 2005-07-28 | I-Com:Kk | フィジカルピーリング用角層剥離粘着シート |
KR20070099540A (ko) | 2004-09-08 | 2007-10-09 | 알자 코포레이션 | 향상된 피부 점착성 및 순응도를 갖는 미세돌출부 어레이 |
JP2007038273A (ja) | 2005-08-04 | 2007-02-15 | Sankyo Kogyo Kk | 段付け加工治具 |
JP5246838B2 (ja) | 2006-03-31 | 2013-07-24 | リンテック株式会社 | 角質剥離用粘着剤組成物および角質剥離用粘着シート |
FR2912643B1 (fr) * | 2007-02-15 | 2009-04-17 | Dbv Technologies Sa | Patch pour application cutanee |
-
2008
- 2008-03-19 EP EP08722483A patent/EP2161050B1/en not_active Not-in-force
- 2008-03-19 KR KR1020107000686A patent/KR101463601B1/ko not_active IP Right Cessation
- 2008-03-19 JP JP2009520377A patent/JP5089691B2/ja not_active Expired - Fee Related
- 2008-03-19 CA CA2691596A patent/CA2691596C/en not_active Expired - Fee Related
- 2008-03-19 WO PCT/JP2008/055108 patent/WO2009001591A1/ja active Application Filing
- 2008-03-19 US US12/666,435 patent/US8071126B2/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS639546Y2 (ja) * | 1981-09-09 | 1988-03-22 | ||
US4627429A (en) * | 1986-02-28 | 1986-12-09 | American Home Products Corporation | Storage-stable transdermal adhesive patch |
US20050034732A1 (en) * | 2003-08-13 | 2005-02-17 | Rousseau Robert A. | Surgical wound closure device |
Also Published As
Publication number | Publication date |
---|---|
EP2161050B1 (en) | 2012-06-27 |
US20100189751A1 (en) | 2010-07-29 |
KR20100027215A (ko) | 2010-03-10 |
WO2009001591A1 (ja) | 2008-12-31 |
CA2691596C (en) | 2014-02-11 |
EP2161050A4 (en) | 2011-05-25 |
CA2691596A1 (en) | 2008-12-31 |
JPWO2009001591A1 (ja) | 2010-08-26 |
US8071126B2 (en) | 2011-12-06 |
EP2161050A1 (en) | 2010-03-10 |
KR101463601B1 (ko) | 2014-11-20 |
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