WO2009001591A1 - 経皮吸収型貼付剤 - Google Patents

経皮吸収型貼付剤 Download PDF

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Publication number
WO2009001591A1
WO2009001591A1 PCT/JP2008/055108 JP2008055108W WO2009001591A1 WO 2009001591 A1 WO2009001591 A1 WO 2009001591A1 JP 2008055108 W JP2008055108 W JP 2008055108W WO 2009001591 A1 WO2009001591 A1 WO 2009001591A1
Authority
WO
WIPO (PCT)
Prior art keywords
drug component
absorption type
transdermal absorption
type patch
support base
Prior art date
Application number
PCT/JP2008/055108
Other languages
English (en)
French (fr)
Inventor
Toru Sekiguchi
Kaname Nakahara
Toru Watanabe
Original Assignee
Lintec Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lintec Corporation filed Critical Lintec Corporation
Priority to EP08722483A priority Critical patent/EP2161050B1/en
Priority to KR1020107000686A priority patent/KR101463601B1/ko
Priority to CA2691596A priority patent/CA2691596C/en
Priority to US12/666,435 priority patent/US8071126B2/en
Priority to JP2009520377A priority patent/JP5089691B2/ja
Publication of WO2009001591A1 publication Critical patent/WO2009001591A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A61M35/006—Portable hand-held applicators having means for dispensing or spreading integral media using sponges, foams, absorbent pads or swabs as spreading means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00544—Plasters form or structure
    • A61F2013/00646—Medication patches, e.g. transcutaneous
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/256—Antibodies, e.g. immunoglobulins, vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/428—Vitamins, e.g. tocopherol, riboflavin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/14—Layer or component removable to expose adhesive
    • Y10T428/149—Sectional layer removable
    • Y10T428/1495—Adhesive is on removable layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

経皮吸収型貼付剤は、第１の支持基材（１１）と、粘着剤層（１２）とで構成された角質層剥離部材（１）と、第２の支持基材（２１）と、薬効成分保持層（２２）と、該薬効成分保持層から剥離可能な保護層（２３）とで構成された薬効成分投与部材（２）と、角質層剥離部材と薬効成分投与部材との間に介挿され、生体表面から角質層剥離部材を剥離する操作と、薬効成分保持層から保護層を剥離する操作とを引っ張りにより一括して行う操作部材（３）とを有している。また、操作部材は、縁部において、第１の支持基材と保護層とに一体化されている。
PCT/JP2008/055108 2007-06-26 2008-03-19 経皮吸収型貼付剤 WO2009001591A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP08722483A EP2161050B1 (en) 2007-06-26 2008-03-19 Transdermal absorption type patch
KR1020107000686A KR101463601B1 (ko) 2007-06-26 2008-03-19 경피흡수형 패치
CA2691596A CA2691596C (en) 2007-06-26 2008-03-19 Percutaneous absorption type patch
US12/666,435 US8071126B2 (en) 2007-06-26 2008-03-19 Percutaneous absorption type patch
JP2009520377A JP5089691B2 (ja) 2007-06-26 2008-03-19 経皮吸収型貼付剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007167294 2007-06-26
JP2007-167294 2007-06-26

Publications (1)

Publication Number Publication Date
WO2009001591A1 true WO2009001591A1 (ja) 2008-12-31

Family

ID=40185415

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/055108 WO2009001591A1 (ja) 2007-06-26 2008-03-19 経皮吸収型貼付剤

Country Status (6)

Country Link
US (1) US8071126B2 (ja)
EP (1) EP2161050B1 (ja)
JP (1) JP5089691B2 (ja)
KR (1) KR101463601B1 (ja)
CA (1) CA2691596C (ja)
WO (1) WO2009001591A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110251561A1 (en) * 2008-07-25 2011-10-13 Lintec Corporation Transdermal administration device
JP2012010966A (ja) * 2010-06-30 2012-01-19 Lintec Corp 角質剥離用粘着シート

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107107598B (zh) 2014-12-18 2019-11-22 3M创新有限公司 处理粘合层合物贴剂的方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6054284B2 (ja) * 1981-01-28 1985-11-29 日東電工株式会社 薬物投与部材
US4627429A (en) * 1986-02-28 1986-12-09 American Home Products Corporation Storage-stable transdermal adhesive patch
JPS639546Y2 (ja) * 1981-09-09 1988-03-22
US20050034732A1 (en) * 2003-08-13 2005-02-17 Rousseau Robert A. Surgical wound closure device
JP2005200391A (ja) 2004-01-14 2005-07-28 I-Com:Kk フィジカルピーリング用角層剥離粘着シート
JP2007038273A (ja) 2005-08-04 2007-02-15 Sankyo Kogyo Kk 段付け加工治具
JP2007289672A (ja) 2006-03-31 2007-11-08 Lintec Corp 角質剥離用粘着剤組成物および角質剥離用粘着シート

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6054284A (ja) 1983-09-03 1985-03-28 Hitachi Constr Mach Co Ltd 溶接スパツタ削除装置
JPS639546A (ja) 1986-07-01 1988-01-16 Canon Inc インク供給装置
GB8721659D0 (en) * 1987-09-15 1987-10-21 Smith & Nephew Ass Adhesive coated dressings & applicators
US4917929A (en) * 1989-01-18 1990-04-17 Minnesota Mining And Manufacturing Company One piece adhesive bandage and package unit
ES2147977T3 (es) * 1996-02-09 2000-10-01 Coloplast As Lengueta.
US6129929A (en) * 1998-10-30 2000-10-10 Noven Pharmaceuticals, Inc. Patch applicator
US6124522A (en) * 1998-11-24 2000-09-26 Schroeder; Mark R. Packaging for adhesive-sided articles to allow one-handed application
US6140549A (en) * 1999-01-13 2000-10-31 Pompei, Jr.; John Anthony Bandage handy strips
FR2794969B1 (fr) * 1999-06-16 2002-01-18 Technosphere Sarl Pansement adhesif
US7027877B2 (en) * 2001-08-23 2006-04-11 Zoll Medical Corporation Method of applying defibrilator electrode pad with folded release sheet
US6945952B2 (en) * 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
US7383084B2 (en) * 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
BRPI0415466A (pt) 2003-10-24 2006-12-19 Alza Corp método e sistema de pré-tratamento para intensificar a distribuição transdérmica de fármacos
EP1786505A1 (en) * 2004-09-08 2007-05-23 Alza Corporation Microprojection array with improved skin adhesion and compliance
FR2912643B1 (fr) * 2007-02-15 2009-04-17 Dbv Technologies Sa Patch pour application cutanee

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6054284B2 (ja) * 1981-01-28 1985-11-29 日東電工株式会社 薬物投与部材
JPS639546Y2 (ja) * 1981-09-09 1988-03-22
US4627429A (en) * 1986-02-28 1986-12-09 American Home Products Corporation Storage-stable transdermal adhesive patch
US20050034732A1 (en) * 2003-08-13 2005-02-17 Rousseau Robert A. Surgical wound closure device
JP2005200391A (ja) 2004-01-14 2005-07-28 I-Com:Kk フィジカルピーリング用角層剥離粘着シート
JP2007038273A (ja) 2005-08-04 2007-02-15 Sankyo Kogyo Kk 段付け加工治具
JP2007289672A (ja) 2006-03-31 2007-11-08 Lintec Corp 角質剥離用粘着剤組成物および角質剥離用粘着シート

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of EP2161050A4
SEO N ET AL., PROC NATL ACAD SCI USA, vol. 97, 2000, pages 371 - 376

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110251561A1 (en) * 2008-07-25 2011-10-13 Lintec Corporation Transdermal administration device
JP2012010966A (ja) * 2010-06-30 2012-01-19 Lintec Corp 角質剥離用粘着シート

Also Published As

Publication number Publication date
EP2161050A4 (en) 2011-05-25
CA2691596A1 (en) 2008-12-31
US20100189751A1 (en) 2010-07-29
JP5089691B2 (ja) 2012-12-05
US8071126B2 (en) 2011-12-06
JPWO2009001591A1 (ja) 2010-08-26
KR20100027215A (ko) 2010-03-10
CA2691596C (en) 2014-02-11
EP2161050B1 (en) 2012-06-27
KR101463601B1 (ko) 2014-11-20
EP2161050A1 (en) 2010-03-10

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