JP5087741B2 - 改良タンパク質発現系 - Google Patents

改良タンパク質発現系 Download PDF

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JP5087741B2
JP5087741B2 JP2006541422A JP2006541422A JP5087741B2 JP 5087741 B2 JP5087741 B2 JP 5087741B2 JP 2006541422 A JP2006541422 A JP 2006541422A JP 2006541422 A JP2006541422 A JP 2006541422A JP 5087741 B2 JP5087741 B2 JP 5087741B2
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gene
sequence
laci
nucleic acid
host cell
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Japanese (ja)
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JP2007511238A (ja
JP2007511238A5 (enExample
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シュナイダー，ジェーン，シー．
チュー，ローレンス，シー．
バグレー，アン，キャスリーン
ラムセイアー，トーマス，マーティン
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フェネックス インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C12N9/0028—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/05—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in nitriles (3.5.5)
    • C12Y305/05001—Nitrilase (3.5.5.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2006541422A 2003-11-19 2004-11-19 改良タンパク質発現系 Expired - Lifetime JP5087741B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US52342003P 2003-11-19 2003-11-19
US60/523,420 2003-11-19
US53714704P 2004-01-16 2004-01-16
US60/537,147 2004-01-16
PCT/US2004/038884 WO2005052151A1 (en) 2003-11-19 2004-11-19 Improved protein expression systems

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011275338A Division JP2012100669A (ja) 2003-11-19 2011-12-16 改良タンパク質発現系

Publications (3)

Publication Number Publication Date
JP2007511238A JP2007511238A (ja) 2007-05-10
JP2007511238A5 JP2007511238A5 (enExample) 2008-01-10
JP5087741B2 true JP5087741B2 (ja) 2012-12-05

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JP2006541422A Expired - Lifetime JP5087741B2 (ja) 2003-11-19 2004-11-19 改良タンパク質発現系
JP2011275338A Pending JP2012100669A (ja) 2003-11-19 2011-12-16 改良タンパク質発現系

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JP2011275338A Pending JP2012100669A (ja) 2003-11-19 2011-12-16 改良タンパク質発現系

Country Status (10)

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US (2) US20050186666A1 (enExample)
EP (1) EP1692282B1 (enExample)
JP (2) JP5087741B2 (enExample)
KR (1) KR101237651B1 (enExample)
CN (1) CN1906294B (enExample)
AU (1) AU2004293810B2 (enExample)
BR (1) BRPI0416744A (enExample)
CA (1) CA2545610C (enExample)
MX (1) MXPA06005634A (enExample)
WO (1) WO2005052151A1 (enExample)

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Publication number Publication date
KR101237651B1 (ko) 2013-02-27
WO2005052151A1 (en) 2005-06-09
KR20060132587A (ko) 2006-12-21
BRPI0416744A (pt) 2007-01-16
US20090325230A1 (en) 2009-12-31
JP2007511238A (ja) 2007-05-10
EP1692282B1 (en) 2012-08-08
US20050186666A1 (en) 2005-08-25
CN1906294A (zh) 2007-01-31
EP1692282A1 (en) 2006-08-23
AU2004293810A1 (en) 2005-06-09
CA2545610C (en) 2014-03-25
AU2004293810B2 (en) 2010-07-01
MXPA06005634A (es) 2006-08-23
JP2012100669A (ja) 2012-05-31
CA2545610A1 (en) 2005-06-09
US8288127B2 (en) 2012-10-16
EP1692282A4 (en) 2008-04-02
CN1906294B (zh) 2013-09-11

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