JP5086988B2 - 乾粉エアロゾル化吸入器 - Google Patents

乾粉エアロゾル化吸入器 Download PDF

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Publication number
JP5086988B2
JP5086988B2 JP2008503352A JP2008503352A JP5086988B2 JP 5086988 B2 JP5086988 B2 JP 5086988B2 JP 2008503352 A JP2008503352 A JP 2008503352A JP 2008503352 A JP2008503352 A JP 2008503352A JP 5086988 B2 JP5086988 B2 JP 5086988B2
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Japan
Prior art keywords
inner diameter
main body
drug
drug loading
mouthpiece
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Expired - Fee Related
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JP2008503352A
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English (en)
Japanese (ja)
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JP2008534091A5 (cg-RX-API-DMAC7.html
JP2008534091A (ja
Inventor
チェン，チンタン
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Publication of JP2008534091A publication Critical patent/JP2008534091A/ja
Publication of JP2008534091A5 publication Critical patent/JP2008534091A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0015—Details of inhalators; Constructional features thereof with inhalation check valves located upstream of the dispenser, i.e. not traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/14—Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
JP2008503352A 2005-04-04 2006-03-13 乾粉エアロゾル化吸入器 Expired - Fee Related JP5086988B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200510038681.1 2005-04-04
CNB2005100386811A CN100431634C (zh) 2005-04-04 2005-04-04 干粉气溶胶化吸入器
PCT/CN2006/000381 WO2006105709A1 (en) 2005-04-04 2006-03-13 Dry powder aerosolizing inhaler

Publications (3)

Publication Number Publication Date
JP2008534091A JP2008534091A (ja) 2008-08-28
JP2008534091A5 JP2008534091A5 (cg-RX-API-DMAC7.html) 2009-05-07
JP5086988B2 true JP5086988B2 (ja) 2012-11-28

Family

ID=35038170

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008503352A Expired - Fee Related JP5086988B2 (ja) 2005-04-04 2006-03-13 乾粉エアロゾル化吸入器

Country Status (6)

Country Link
US (1) US8978645B2 (cg-RX-API-DMAC7.html)
EP (1) EP1872817B1 (cg-RX-API-DMAC7.html)
JP (1) JP5086988B2 (cg-RX-API-DMAC7.html)
CN (1) CN100431634C (cg-RX-API-DMAC7.html)
AT (1) ATE539785T1 (cg-RX-API-DMAC7.html)
WO (1) WO2006105709A1 (cg-RX-API-DMAC7.html)

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DE602005024413D1 (de) 2004-08-20 2010-12-09 Mannkind Corp Katalyse der diketopiperazinsynthese
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
JP5167133B2 (ja) 2005-09-14 2013-03-21 マンカインド コーポレイション 結晶性微粒子表面に対する活性薬剤の親和性の増大に基づく薬物処方の方法
MX2008010721A (es) 2006-02-22 2008-09-01 Mannkind Corp Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo.
ES2394589T3 (es) 2007-12-14 2013-02-04 Aerodesigns, Inc Suministro de productos alimenticios transformables en aerosol
JP5421362B2 (ja) 2008-06-13 2014-02-19 マンカインド コーポレイション 薬物送達用の乾燥粉末吸入器およびシステム
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
RU2470681C2 (ru) * 2008-06-20 2012-12-27 Маннкайнд Корпорейшн Интерактивное устройство и способ профилирования усилий при ингаляции в реальном масштабе времени
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2405963B1 (en) 2009-03-11 2013-11-06 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8551528B2 (en) 2009-06-12 2013-10-08 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
GB2472327B (en) 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
JP6385673B2 (ja) 2010-06-21 2018-09-05 マンカインド コーポレイション 乾燥粉末薬物送達システム
CN102553040B (zh) * 2010-12-17 2014-07-02 陈庆堂 滤出药粉吸入器
KR20140003582A (ko) 2011-01-31 2014-01-09 신 니뽄 바이오메디칼 라보라토리즈, 엘티디. 비강내 전달 장치
WO2012135765A2 (en) 2011-04-01 2012-10-04 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
IN2014DN03093A (cg-RX-API-DMAC7.html) 2011-10-24 2015-05-15 Mannkind Corp
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
ES2754388T3 (es) 2013-03-15 2020-04-17 Mannkind Corp Composiciones y métodos de dicetopiperazina microcristalina
AU2014290438B2 (en) 2013-07-18 2019-11-07 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN106075677B (zh) * 2016-08-08 2022-06-10 中山市美捷时包装制品有限公司 一种干粉吸入装置的促动机构
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN109821118B (zh) * 2017-11-23 2025-12-23 正大天晴药业集团股份有限公司 新型肺部药物输送系统
CN111801026B (zh) * 2018-03-26 2024-04-19 菲利普莫里斯生产公司 具有有孔的多孔支撑元件的吸入器
CN115702961A (zh) * 2021-08-03 2023-02-17 上海臣邦医药科技股份有限公司 一种单剂量可抛弃型粉雾剂装置

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FI69963C (fi) * 1984-10-04 1986-09-12 Orion Yhtymae Oy Doseringsanordning
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
DE4211475A1 (de) 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5239993A (en) * 1992-08-26 1993-08-31 Glaxo Inc. Dosage inhalator providing optimized compound inhalation trajectory
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
CZ295827B6 (cs) * 1994-03-07 2005-11-16 Nektar Therapeutics Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití
FR2718968B1 (fr) * 1994-04-20 1996-07-26 Valois Sa Insert délimitant une chambre de dosage d'un inhalateur.
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GB9626263D0 (en) * 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
JP3530004B2 (ja) 1998-02-06 2004-05-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
US6234169B1 (en) * 1998-08-14 2001-05-22 Arthur Slutsky Inhaler
JP2000217917A (ja) * 1999-01-27 2000-08-08 Unisia Jecs Corp 吸入式投薬器
JP2000217919A (ja) * 1999-01-28 2000-08-08 Unisia Jecs Corp 吸入式投薬器
GB2353222B (en) * 1999-06-23 2001-09-19 Cambridge Consultants Inhalers
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
CN2391625Y (zh) 1999-11-07 2000-08-16 范崇盛 新型多用途雾化吸入器
GB0015043D0 (en) 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
AR028746A1 (es) * 2000-06-23 2003-05-21 Norton Health Care Ltd Cartucho de dosis previamente medidas para inhalador de polvo seco accionado por la respiracion, el inhalador y un metodo de provision de dosis previamente medidas de polvo seco
DE10040528A1 (de) * 2000-08-18 2002-02-28 Pari Gmbh Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke
ATE503517T2 (de) * 2002-07-31 2011-04-15 Chiesi Farma Spa Pulverinhalator
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JP3616877B2 (ja) * 2002-10-11 2005-02-02 大塚製薬株式会社 粉末吸入器
JP3590848B1 (ja) * 2003-05-09 2004-11-17 大塚製薬株式会社 粉末吸入器
CN2794531Y (zh) * 2005-04-04 2006-07-12 陈庆堂 干粉气溶胶化吸入器

Also Published As

Publication number Publication date
EP1872817A1 (en) 2008-01-02
US20090025720A1 (en) 2009-01-29
EP1872817A4 (en) 2010-07-14
WO2006105709A1 (en) 2006-10-12
JP2008534091A (ja) 2008-08-28
ATE539785T1 (de) 2012-01-15
CN1666788A (zh) 2005-09-14
US8978645B2 (en) 2015-03-17
CN100431634C (zh) 2008-11-12
EP1872817B1 (en) 2012-01-04

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