JP2008534091A5 - - Google Patents
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- Publication number
- JP2008534091A5 JP2008534091A5 JP2008503352A JP2008503352A JP2008534091A5 JP 2008534091 A5 JP2008534091 A5 JP 2008534091A5 JP 2008503352 A JP2008503352 A JP 2008503352A JP 2008503352 A JP2008503352 A JP 2008503352A JP 2008534091 A5 JP2008534091 A5 JP 2008534091A5
- Authority
- JP
- Japan
- Prior art keywords
- dry
- main body
- inner diameter
- powder
- loading inlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims description 71
- 229940079593 drug Drugs 0.000 claims description 62
- 239000000843 powder Substances 0.000 claims description 44
- 230000000149 penetrating effect Effects 0.000 claims description 6
- 238000012387 aerosolization Methods 0.000 claims description 5
- 210000000214 mouth Anatomy 0.000 description 17
- 238000010586 diagram Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 210000002345 respiratory system Anatomy 0.000 description 5
- 239000000443 aerosol Substances 0.000 description 4
- 239000008187 granular material Substances 0.000 description 3
- 230000009885 systemic effect Effects 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- 229940112141 dry powder inhaler Drugs 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 210000003800 pharynx Anatomy 0.000 description 2
- 206010011409 Cross infection Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 208000018569 Respiratory Tract disease Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200510038681.1 | 2005-04-04 | ||
| CNB2005100386811A CN100431634C (zh) | 2005-04-04 | 2005-04-04 | 干粉气溶胶化吸入器 |
| PCT/CN2006/000381 WO2006105709A1 (en) | 2005-04-04 | 2006-03-13 | Dry powder aerosolizing inhaler |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008534091A JP2008534091A (ja) | 2008-08-28 |
| JP2008534091A5 true JP2008534091A5 (cg-RX-API-DMAC7.html) | 2009-05-07 |
| JP5086988B2 JP5086988B2 (ja) | 2012-11-28 |
Family
ID=35038170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503352A Expired - Fee Related JP5086988B2 (ja) | 2005-04-04 | 2006-03-13 | 乾粉エアロゾル化吸入器 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8978645B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1872817B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5086988B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN100431634C (cg-RX-API-DMAC7.html) |
| AT (1) | ATE539785T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006105709A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| ATE385193T1 (de) | 2002-03-20 | 2008-02-15 | Mannkind Corp | Inhalationsgerät |
| DE602005024413D1 (de) | 2004-08-20 | 2010-12-09 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| CN104436170B (zh) | 2004-08-23 | 2018-02-23 | 曼金德公司 | 用于药物输送的二酮哌嗪盐 |
| JP5167133B2 (ja) | 2005-09-14 | 2013-03-21 | マンカインド コーポレイション | 結晶性微粒子表面に対する活性薬剤の親和性の増大に基づく薬物処方の方法 |
| MX2008010721A (es) | 2006-02-22 | 2008-09-01 | Mannkind Corp | Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo. |
| ES2394589T3 (es) | 2007-12-14 | 2013-02-04 | Aerodesigns, Inc | Suministro de productos alimenticios transformables en aerosol |
| JP5421362B2 (ja) | 2008-06-13 | 2014-02-19 | マンカインド コーポレイション | 薬物送達用の乾燥粉末吸入器およびシステム |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| RU2470681C2 (ru) * | 2008-06-20 | 2012-12-27 | Маннкайнд Корпорейшн | Интерактивное устройство и способ профилирования усилий при ингаляции в реальном масштабе времени |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2405963B1 (en) | 2009-03-11 | 2013-11-06 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| US8551528B2 (en) | 2009-06-12 | 2013-10-08 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
| GB2472327B (en) | 2009-07-31 | 2013-03-13 | Shin Nippon Biomedical Lab Ltd | Intranasal granisetron and nasal applicator |
| EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
| JP6385673B2 (ja) | 2010-06-21 | 2018-09-05 | マンカインド コーポレイション | 乾燥粉末薬物送達システム |
| CN102553040B (zh) * | 2010-12-17 | 2014-07-02 | 陈庆堂 | 滤出药粉吸入器 |
| KR20140003582A (ko) | 2011-01-31 | 2014-01-09 | 신 니뽄 바이오메디칼 라보라토리즈, 엘티디. | 비강내 전달 장치 |
| WO2012135765A2 (en) | 2011-04-01 | 2012-10-04 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| IN2014DN03093A (cg-RX-API-DMAC7.html) | 2011-10-24 | 2015-05-15 | Mannkind Corp | |
| AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| ES2754388T3 (es) | 2013-03-15 | 2020-04-17 | Mannkind Corp | Composiciones y métodos de dicetopiperazina microcristalina |
| AU2014290438B2 (en) | 2013-07-18 | 2019-11-07 | Mannkind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
| JP2016530930A (ja) | 2013-08-05 | 2016-10-06 | マンカインド コーポレイション | 通気装置及び方法 |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| CN106075677B (zh) * | 2016-08-08 | 2022-06-10 | 中山市美捷时包装制品有限公司 | 一种干粉吸入装置的促动机构 |
| US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
| CN109821118B (zh) * | 2017-11-23 | 2025-12-23 | 正大天晴药业集团股份有限公司 | 新型肺部药物输送系统 |
| CN111801026B (zh) * | 2018-03-26 | 2024-04-19 | 菲利普莫里斯生产公司 | 具有有孔的多孔支撑元件的吸入器 |
| CN115702961A (zh) * | 2021-08-03 | 2023-02-17 | 上海臣邦医药科技股份有限公司 | 一种单剂量可抛弃型粉雾剂装置 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI69963C (fi) * | 1984-10-04 | 1986-09-12 | Orion Yhtymae Oy | Doseringsanordning |
| US5201308A (en) * | 1990-02-14 | 1993-04-13 | Newhouse Michael T | Powder inhaler |
| GB9015522D0 (en) * | 1990-07-13 | 1990-08-29 | Braithwaite Philip W | Inhaler |
| DE4211475A1 (de) | 1991-12-14 | 1993-06-17 | Asta Medica Ag | Pulverinhalator |
| US5239993A (en) * | 1992-08-26 | 1993-08-31 | Glaxo Inc. | Dosage inhalator providing optimized compound inhalation trajectory |
| US5349947A (en) * | 1993-07-15 | 1994-09-27 | Newhouse Michael T | Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow |
| CZ295827B6 (cs) * | 1994-03-07 | 2005-11-16 | Nektar Therapeutics | Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití |
| FR2718968B1 (fr) * | 1994-04-20 | 1996-07-26 | Valois Sa | Insert délimitant une chambre de dosage d'un inhalateur. |
| DE59610935D1 (de) * | 1995-12-07 | 2004-04-15 | Jago Res Ag Muttenz | Mundstück für einen Inhalator zur mehrfachen dosisweisen Abgabe eines pharmakologischen Trockenpulvers |
| JP3328131B2 (ja) * | 1996-03-15 | 2002-09-24 | 株式会社ユニシアジェックス | 吸入式投薬器 |
| GB9626263D0 (en) * | 1996-12-18 | 1997-02-05 | Innovata Biomed Ltd | Powder inhaler |
| JP3530004B2 (ja) | 1998-02-06 | 2004-05-24 | 株式会社日立ユニシアオートモティブ | 吸入式投薬器 |
| US6234169B1 (en) * | 1998-08-14 | 2001-05-22 | Arthur Slutsky | Inhaler |
| JP2000217917A (ja) * | 1999-01-27 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| JP2000217919A (ja) * | 1999-01-28 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| GB2353222B (en) * | 1999-06-23 | 2001-09-19 | Cambridge Consultants | Inhalers |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| CN2391625Y (zh) | 1999-11-07 | 2000-08-16 | 范崇盛 | 新型多用途雾化吸入器 |
| GB0015043D0 (en) | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
| AR028746A1 (es) * | 2000-06-23 | 2003-05-21 | Norton Health Care Ltd | Cartucho de dosis previamente medidas para inhalador de polvo seco accionado por la respiracion, el inhalador y un metodo de provision de dosis previamente medidas de polvo seco |
| DE10040528A1 (de) * | 2000-08-18 | 2002-02-28 | Pari Gmbh | Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke |
| ATE503517T2 (de) * | 2002-07-31 | 2011-04-15 | Chiesi Farma Spa | Pulverinhalator |
| DE10244795A1 (de) * | 2002-09-26 | 2004-04-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| JP3616877B2 (ja) * | 2002-10-11 | 2005-02-02 | 大塚製薬株式会社 | 粉末吸入器 |
| JP3590848B1 (ja) * | 2003-05-09 | 2004-11-17 | 大塚製薬株式会社 | 粉末吸入器 |
| CN2794531Y (zh) * | 2005-04-04 | 2006-07-12 | 陈庆堂 | 干粉气溶胶化吸入器 |
-
2005
- 2005-04-04 CN CNB2005100386811A patent/CN100431634C/zh not_active Expired - Fee Related
-
2006
- 2006-03-13 WO PCT/CN2006/000381 patent/WO2006105709A1/zh not_active Ceased
- 2006-03-13 EP EP06722039A patent/EP1872817B1/en not_active Revoked
- 2006-03-13 US US11/887,755 patent/US8978645B2/en not_active Expired - Fee Related
- 2006-03-13 JP JP2008503352A patent/JP5086988B2/ja not_active Expired - Fee Related
- 2006-03-13 AT AT06722039T patent/ATE539785T1/de active
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