JP5068857B2 - 有機化合物 - Google Patents
有機化合物 Download PDFInfo
- Publication number
- JP5068857B2 JP5068857B2 JP2010536936A JP2010536936A JP5068857B2 JP 5068857 B2 JP5068857 B2 JP 5068857B2 JP 2010536936 A JP2010536936 A JP 2010536936A JP 2010536936 A JP2010536936 A JP 2010536936A JP 5068857 B2 JP5068857 B2 JP 5068857B2
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- JP
- Japan
- Prior art keywords
- formula
- compound
- alkyl
- methyl
- halo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 *N(C(CC(N1)=O)=O)C1=O Chemical compound *N(C(CC(N1)=O)=O)C1=O 0.000 description 5
- HYIVECJPQVDTHM-VEWOAAGWSA-N C/C(/C(F)(F)F)=C\N=C(/C)\c1ccc(C[n](c(N2C(N3C)=NC4[C@@H]2CCC4)c2C3=O)nc2Nc2ccccc2)cc1 Chemical compound C/C(/C(F)(F)F)=C\N=C(/C)\c1ccc(C[n](c(N2C(N3C)=NC4[C@@H]2CCC4)c2C3=O)nc2Nc2ccccc2)cc1 HYIVECJPQVDTHM-VEWOAAGWSA-N 0.000 description 1
- WMUJUOGDAYGNQB-KVJCIMDZSA-N CC(CN(C)C)C[n](c(N1C(N2C)=N[C@H]3[C@@H]1CCC3)c1C2=O)nc1Nc1ccccc1 Chemical compound CC(CN(C)C)C[n](c(N1C(N2C)=N[C@H]3[C@@H]1CCC3)c1C2=O)nc1Nc1ccccc1 WMUJUOGDAYGNQB-KVJCIMDZSA-N 0.000 description 1
- BJVZWFYSLQZWIB-ZHDBWKLFSA-N CN(C(/C1=C(/NCc(cc2)ccc2-c2cc(F)ccn2)\Nc2ccccc2)=O)N[C@H](CCC2)[C@H]2NC1=N Chemical compound CN(C(/C1=C(/NCc(cc2)ccc2-c2cc(F)ccn2)\Nc2ccccc2)=O)N[C@H](CCC2)[C@H]2NC1=N BJVZWFYSLQZWIB-ZHDBWKLFSA-N 0.000 description 1
- JKNRLIQBXDWJGU-WTQRLHSKSA-N CN(C1=N[C@H](CCC2)C2N1c1c2c(Nc3ccccc3)n[n]1Cc(cc1)ccc1-c(nccc1)c1F)C2=O Chemical compound CN(C1=N[C@H](CCC2)C2N1c1c2c(Nc3ccccc3)n[n]1Cc(cc1)ccc1-c(nccc1)c1F)C2=O JKNRLIQBXDWJGU-WTQRLHSKSA-N 0.000 description 1
- PCMLXAWFTZRKFN-CHENDWDOSA-N CN(C1=N[C@H](CCC2)[C@H]2N1C(/C1=C(\NCc(cc2)cc(F)c2C(C(F)(F)F)=O)/Nc2ccccc2)=N)C1=O Chemical compound CN(C1=N[C@H](CCC2)[C@H]2N1C(/C1=C(\NCc(cc2)cc(F)c2C(C(F)(F)F)=O)/Nc2ccccc2)=N)C1=O PCMLXAWFTZRKFN-CHENDWDOSA-N 0.000 description 1
- PWFLQDHOOBUASD-KLGLKMQGSA-N CN(C1=N[C@H](CCC2)[C@H]2N1C(C1C(NC(c(cc2)ccc2-c(cc2)ncc2F)Br)Nc2ccccc2)=N)C1=O Chemical compound CN(C1=N[C@H](CCC2)[C@H]2N1C(C1C(NC(c(cc2)ccc2-c(cc2)ncc2F)Br)Nc2ccccc2)=N)C1=O PWFLQDHOOBUASD-KLGLKMQGSA-N 0.000 description 1
- OMBGEQYHSKDSRN-PKTZIBPZSA-N CN(C1=N[C@H](CCC2)[C@H]2N1c1c2c(Nc3ccccc3)n[n]1Cc(cc1)ccc1-c1cccc(F)n1)C2=O Chemical compound CN(C1=N[C@H](CCC2)[C@H]2N1c1c2c(Nc3ccccc3)n[n]1Cc(cc1)ccc1-c1cccc(F)n1)C2=O OMBGEQYHSKDSRN-PKTZIBPZSA-N 0.000 description 1
- FSIOOOYSAVPZLQ-RPWUZVMVSA-N CN(C1=N[C@H](CCC2)[C@H]2N1c1n[n](Cc(cc2)ccc2-c(nc2)ccc2F)c(Nc2ccccc2)c11)C1=O Chemical compound CN(C1=N[C@H](CCC2)[C@H]2N1c1n[n](Cc(cc2)ccc2-c(nc2)ccc2F)c(Nc2ccccc2)c11)C1=O FSIOOOYSAVPZLQ-RPWUZVMVSA-N 0.000 description 1
- CBBDWKAKYFYQCS-PKTZIBPZSA-N CN(C1=N[C@H](CCC2)[C@H]2N1c1n[n](Cc(cc2)ccc2-c(nccc2)c2F)c(Nc2ccccc2)c11)C1=O Chemical compound CN(C1=N[C@H](CCC2)[C@H]2N1c1n[n](Cc(cc2)ccc2-c(nccc2)c2F)c(Nc2ccccc2)c11)C1=O CBBDWKAKYFYQCS-PKTZIBPZSA-N 0.000 description 1
- NICOUVAAVGPGHX-ZWKOTPCHSA-N CN1N[C@H](CCC2)[C@H]2NC(NCC2CCOCC2)=C(C(Nc2ccccc2)=N)C1=O Chemical compound CN1N[C@H](CCC2)[C@H]2NC(NCC2CCOCC2)=C(C(Nc2ccccc2)=N)C1=O NICOUVAAVGPGHX-ZWKOTPCHSA-N 0.000 description 1
- MHZOLPHDEHVQSY-RBUKOAKNSA-N CN1N[C@H](CCC2)[C@H]2NC(NCc2ccc(C(C(F)(F)F)=O)c(F)c2)=C(C(Nc2ccccc2)=N)C1=O Chemical compound CN1N[C@H](CCC2)[C@H]2NC(NCc2ccc(C(C(F)(F)F)=O)c(F)c2)=C(C(Nc2ccccc2)=N)C1=O MHZOLPHDEHVQSY-RBUKOAKNSA-N 0.000 description 1
- PLPNKGRFDHZWGG-GEVKEYJPSA-N Cc(c(Nc1ccccc1)n[n]1Cc(cc2)ccc2-c(cc2)ncc2F)c1N1C(N(C)C=O)=NC2[C@@H]1CCC2 Chemical compound Cc(c(Nc1ccccc1)n[n]1Cc(cc2)ccc2-c(cc2)ncc2F)c1N1C(N(C)C=O)=NC2[C@@H]1CCC2 PLPNKGRFDHZWGG-GEVKEYJPSA-N 0.000 description 1
- JFFOUICIRBXFRC-RFZPGFLSSA-N N[C@H](CCC1)[C@@H]1O Chemical compound N[C@H](CCC1)[C@@H]1O JFFOUICIRBXFRC-RFZPGFLSSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61P15/06—Antiabortive agents; Labour repressants
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- A—HUMAN NECESSITIES
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Addiction (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1204007P | 2007-12-06 | 2007-12-06 | |
US61/012,040 | 2007-12-06 | ||
PCT/US2008/013411 WO2009075784A1 (fr) | 2007-12-06 | 2008-12-06 | Composés organiques |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012095588A Division JP5536135B2 (ja) | 2007-12-06 | 2012-04-19 | 有機化合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2011506321A JP2011506321A (ja) | 2011-03-03 |
JP5068857B2 true JP5068857B2 (ja) | 2012-11-07 |
Family
ID=40755776
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010536936A Active JP5068857B2 (ja) | 2007-12-06 | 2008-12-06 | 有機化合物 |
JP2012095588A Active JP5536135B2 (ja) | 2007-12-06 | 2012-04-19 | 有機化合物 |
JP2014089334A Pending JP2014148534A (ja) | 2007-12-06 | 2014-04-23 | 有機化合物 |
JP2015203116A Pending JP2016190834A (ja) | 2007-12-06 | 2015-10-14 | 有機化合物 |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012095588A Active JP5536135B2 (ja) | 2007-12-06 | 2012-04-19 | 有機化合物 |
JP2014089334A Pending JP2014148534A (ja) | 2007-12-06 | 2014-04-23 | 有機化合物 |
JP2015203116A Pending JP2016190834A (ja) | 2007-12-06 | 2015-10-14 | 有機化合物 |
Country Status (17)
Country | Link |
---|---|
US (3) | US8273751B2 (fr) |
EP (3) | EP2240490B1 (fr) |
JP (4) | JP5068857B2 (fr) |
KR (2) | KR101227738B1 (fr) |
CN (7) | CN104370919A (fr) |
AU (1) | AU2008335811B2 (fr) |
CA (2) | CA2707349C (fr) |
DK (1) | DK2240490T3 (fr) |
ES (1) | ES2436780T3 (fr) |
HK (6) | HK1207628A1 (fr) |
HR (1) | HRP20131073T1 (fr) |
IL (2) | IL206096A (fr) |
MX (1) | MX2010006212A (fr) |
PL (1) | PL2240490T3 (fr) |
PT (1) | PT2240490E (fr) |
SI (1) | SI2240490T1 (fr) |
WO (1) | WO2009075784A1 (fr) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012167099A (ja) * | 2007-12-06 | 2012-09-06 | Takeda Chem Ind Ltd | 有機化合物 |
US9849132B2 (en) | 2014-01-08 | 2017-12-26 | Intra-Cellular Therapies, Inc. | Products and pharmaceutical compositions |
US10105349B2 (en) | 2014-12-06 | 2018-10-23 | Intra-Cellular Therapies, Inc. | Organic compounds |
US10300064B2 (en) | 2014-12-06 | 2019-05-28 | Intra-Cellular Therapies, Inc. | Organic compounds |
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Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003020702A2 (fr) | 2001-08-31 | 2003-03-13 | The Rockefeller University | Activite de phosphodiesterase et regulation de la signalisation a mediation par phosphodiesterase 1-b dans le cerveau |
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WO2009073210A1 (fr) * | 2007-12-06 | 2009-06-11 | Intra-Cellular Therapies, Inc | Composés organiques |
EP2370080A1 (fr) * | 2008-12-02 | 2011-10-05 | University of Utah Research Foundation | Pde1 en tant que cible thérapeutique dans les maladies cardiaques |
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MX2011005935A (es) | 2008-12-06 | 2011-12-16 | Intra Cellular Therapies Inc | Compuestos organicos. |
CA2740396A1 (fr) | 2008-12-06 | 2010-06-10 | Intra-Cellular Therapies, Inc. | Composes organiques |
BRPI0922808A2 (pt) | 2008-12-06 | 2018-05-29 | Intracellular Therapies Inc | compostos orgânicos |
EP2400970A4 (fr) | 2009-02-25 | 2012-07-18 | Intra Cellular Therapies Inc | Inhibiteur de pde 1 pour troubles ophtalmiques |
WO2010132127A1 (fr) | 2009-05-13 | 2010-11-18 | Intra-Cellular Therapies, Inc. | Composés organiques |
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TW201206937A (en) | 2010-05-31 | 2012-02-16 | Intra Cellular Therapies Inc | Organic compounds |
WO2011153135A1 (fr) * | 2010-05-31 | 2011-12-08 | Intra-Cellular Therapies, Inc. | Composés organiques |
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JP6810613B2 (ja) * | 2014-06-20 | 2021-01-06 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 有機化合物 |
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JP6591530B2 (ja) | 2014-08-07 | 2019-10-16 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 有機化合物 |
US10005789B2 (en) | 2014-08-07 | 2018-06-26 | Intra-Cellular Therapies, Inc. | Organic compounds |
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CN107106563B (zh) | 2014-09-17 | 2021-05-25 | 细胞内治疗公司 | 化合物和方法 |
US10287269B2 (en) | 2015-03-26 | 2019-05-14 | Merck Sharp & Dohme Corp. | Pyrazolyl pyrimidinone compounds as PDE2 inhibitors |
US10682354B2 (en) | 2016-03-28 | 2020-06-16 | Intra-Cellular Therapies, Inc. | Compositions and methods |
JP7134168B6 (ja) | 2016-09-12 | 2024-02-02 | イントラ-セルラー・セラピーズ・インコーポレイテッド | 新規使用 |
CN110337437B (zh) | 2016-12-28 | 2023-02-03 | 达特神经科学有限公司 | 作为pde2抑制剂的取代的吡唑并嘧啶酮化合物 |
JP7254078B2 (ja) | 2017-11-27 | 2023-04-07 | ダート・ニューロサイエンス・エルエルシー | Pde1阻害剤としての置換フラノピリミジン化合物 |
JP7401442B2 (ja) | 2018-01-31 | 2023-12-19 | イントラ-セルラー・セラピーズ・インコーポレイテッド | 新規使用 |
WO2020086481A1 (fr) * | 2018-10-21 | 2020-04-30 | Intra-Cellular Therapies, Inc. | Nouvelles utilisations |
US11628171B2 (en) | 2019-03-13 | 2023-04-18 | Children's Medical Center Corporation | Method for treating brain or nerve injury |
WO2020210614A1 (fr) * | 2019-04-12 | 2020-10-15 | Intra-Cellular Therapies, Inc. | Composés organiques |
US20210369715A1 (en) * | 2020-06-02 | 2021-12-02 | Intra-Cellular Therapies, Inc. | Novel uses |
WO2023034965A2 (fr) * | 2021-09-03 | 2023-03-09 | Intra-Cellular Therapies, Inc. | Co-cristaux |
WO2023147603A2 (fr) * | 2022-01-31 | 2023-08-03 | Intra-Cellular Therapies, Inc. | Cristaux de sel |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4666908A (en) | 1985-04-05 | 1987-05-19 | Warner-Lambert Company | 5-Substituted pyrazolo[4,3-d]pyrimidine-7-ones and methods of use |
KR920004437B1 (ko) | 1989-09-12 | 1992-06-05 | 삼성전자 주식회사 | 금전등록기의 거래선 관리방법 |
NZ238609A (en) | 1990-06-21 | 1993-12-23 | Schering Corp | Polycyclic guanine derivatives; preparation, pharmaceutical compositions, |
US5294612A (en) * | 1992-03-30 | 1994-03-15 | Sterling Winthrop Inc. | 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof |
JPH08507068A (ja) * | 1993-02-26 | 1996-07-30 | シェリング・コーポレーション | 2−ベンジル−多環式グアニン誘導体およびそれらの製造方法 |
US5824683A (en) | 1995-11-28 | 1998-10-20 | Schering Corporation | 2'- 4'-halo- 1,1'-biphenyl!-4-yl!methyl!-5'-methyl-spiro cyclopentane-1,7' (8'H)- 3H! imidazo 2,1-b!purin!-4' (5'H)-ones |
SE9701398D0 (sv) | 1997-04-15 | 1997-04-15 | Astra Pharma Prod | Novel compounds |
IT1291372B1 (it) | 1997-05-21 | 1999-01-07 | Schering Plough S P A | Uso di analoghi eterociclici di 1,2,4-triazolo (1,5-c) pirimidine per la preparazione di medicamenti utili per il trattamento delle malattie |
US6013621A (en) * | 1997-10-17 | 2000-01-11 | The Rockfeller University | Method of treating psychosis and/or hyperactivity |
GB9722520D0 (en) | 1997-10-24 | 1997-12-24 | Pfizer Ltd | Compounds |
DE19931206A1 (de) | 1999-07-07 | 2001-01-11 | Stief Christian | Arzneimittel zur Erhöhung des cAMP-Spiegels und deren Verwendung |
SK4562002A3 (en) * | 1999-10-11 | 2003-04-01 | Pfizer | 5-(2-substituted-5-heterocyclylsulphonylpyrid-3-yl)- dihydropyrazolo[4,3-d]pyrimidin-7-ones as phosphodiesterase inhibitors |
IL139073A0 (en) * | 1999-10-21 | 2001-11-25 | Pfizer | Treatment of neuropathy |
US20020006926A1 (en) * | 2000-04-19 | 2002-01-17 | Roylance H. H. | Use of cyclic GMP-specific phosphodiesterase inhibitors for treatment of parkinson's disease |
SE0102315D0 (sv) | 2001-06-28 | 2001-06-28 | Astrazeneca Ab | Compounds |
CN1781920A (zh) * | 2001-08-28 | 2006-06-07 | 先灵公司 | 多环鸟嘌呤磷酸二酯酶v抑制剂 |
WO2003020702A2 (fr) | 2001-08-31 | 2003-03-13 | The Rockefeller University | Activite de phosphodiesterase et regulation de la signalisation a mediation par phosphodiesterase 1-b dans le cerveau |
MXPA04004370A (es) | 2001-11-09 | 2004-08-11 | Schering Corp | Derivados policiclicos de guanina inhibidores de fosfodiesterasa v. |
AU2003219838B2 (en) * | 2002-02-21 | 2007-09-13 | The Rockefeller University | Compositions and method for regulation of calcium-dependent signalling in brain |
WO2004087906A1 (fr) | 2003-03-31 | 2004-10-14 | Pfizer Products Inc. | Structure cristalline de 3',5'-phosphodiesterase nucleotidique cyclique 1d(pde1b) et ses utilisations |
AU2004226353A1 (en) | 2003-04-01 | 2004-10-14 | Laboratoires Serono Sa | Inhibitors of phosphodiesterases in infertility |
ZA200507228B (en) * | 2003-04-01 | 2007-03-28 | Applied Research Systems | Inhibitors of phosphodiesterases in infertility |
AU2006255028B2 (en) * | 2005-06-06 | 2012-04-19 | Intra-Cellular Therapies, Inc. | Organic compounds |
WO2007025103A2 (fr) * | 2005-08-23 | 2007-03-01 | Intra-Cellular Therapies, Inc. | Composes organiques |
US9255099B2 (en) * | 2006-06-06 | 2016-02-09 | Intra-Cellular Therapies, Inc. | Pyrazolo[3,4-D]pyrimidine-4,6(5H,7H)-diones as phosphodiesterase 1 inhibitors |
JP2010509399A (ja) * | 2006-11-13 | 2010-03-25 | イントラ−セルラー・セラピーズ・インコーポレイテッド | 有機化合物 |
JP5837278B2 (ja) | 2006-12-05 | 2015-12-24 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 新規使用 |
HRP20131073T1 (hr) | 2007-12-06 | 2014-01-31 | Takeda Pharmaceutical Company Limited | Organski spojevi |
WO2009073210A1 (fr) | 2007-12-06 | 2009-06-11 | Intra-Cellular Therapies, Inc | Composés organiques |
MA32940B1 (fr) | 2008-12-06 | 2012-01-02 | Intra Cellular Therapies Inc | Composes organiques |
MX2011005935A (es) | 2008-12-06 | 2011-12-16 | Intra Cellular Therapies Inc | Compuestos organicos. |
MA32937B1 (fr) | 2008-12-06 | 2012-01-02 | Intra Cellular Therapies Inc | Composes organiques |
CA2740396A1 (fr) * | 2008-12-06 | 2010-06-10 | Intra-Cellular Therapies, Inc. | Composes organiques |
ES2638912T3 (es) | 2008-12-06 | 2017-10-24 | Intra-Cellular Therapies, Inc. | Compuestos orgánicos |
BRPI0922808A2 (pt) | 2008-12-06 | 2018-05-29 | Intracellular Therapies Inc | compostos orgânicos |
EP2400970A4 (fr) * | 2009-02-25 | 2012-07-18 | Intra Cellular Therapies Inc | Inhibiteur de pde 1 pour troubles ophtalmiques |
WO2010132127A1 (fr) * | 2009-05-13 | 2010-11-18 | Intra-Cellular Therapies, Inc. | Composés organiques |
WO2011043816A1 (fr) | 2009-10-08 | 2011-04-14 | Intra-Cellular Therapies, Inc. | Traceurs ciblant la phosphodiestérase 1 et méthodes associées |
TW201206937A (en) | 2010-05-31 | 2012-02-16 | Intra Cellular Therapies Inc | Organic compounds |
WO2011153135A1 (fr) | 2010-05-31 | 2011-12-08 | Intra-Cellular Therapies, Inc. | Composés organiques |
WO2011153138A1 (fr) | 2010-05-31 | 2011-12-08 | Intra-Cellular Therapies, Inc. | Composés organiques |
WO2011153136A1 (fr) | 2010-05-31 | 2011-12-08 | Intra-Cellular Therapies, Inc. | Composés organiques |
US10561656B2 (en) | 2011-06-10 | 2020-02-18 | Intra-Cellular Therapies, Inc. | Organic compounds |
AR091507A1 (es) | 2012-06-21 | 2015-02-11 | Intra Cellular Therapies Inc | SALES DE (6aR,9aS)-5,6a,7,8,9,9a-HEXAHIDRO-5-METIL-3-(FENILAMINO)-2-((4-(6-FLUOROPIRIDIN-2-IL)FENIL)METIL)-CICLOPENT[4,5]IMIDAZO[1,2-a]PIRAZOLO[4,3-e]PIRIMIDIN-4(2H)-ONA |
JP6437519B2 (ja) | 2013-03-15 | 2018-12-12 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 有機化合物 |
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