JP5019946B2 - ベニクスノキタケ抽出物化合物の腫瘍細胞生長抑制に対する応用 - Google Patents
ベニクスノキタケ抽出物化合物の腫瘍細胞生長抑制に対する応用 Download PDFInfo
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- JP5019946B2 JP5019946B2 JP2007127689A JP2007127689A JP5019946B2 JP 5019946 B2 JP5019946 B2 JP 5019946B2 JP 2007127689 A JP2007127689 A JP 2007127689A JP 2007127689 A JP2007127689 A JP 2007127689A JP 5019946 B2 JP5019946 B2 JP 5019946B2
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- ZPSJWLSADLCKBZ-BJLSYBTBSA-N antcin F Natural products C[C@H](CCC(=C)[C@H](C)C(=O)O)[C@H]1CC=C2C3=C(C(=O)C[C@]12C)[C@@]4(C)CCC(=O)[C@@H](C)[C@@H]4C[C@@H]3O ZPSJWLSADLCKBZ-BJLSYBTBSA-N 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
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- 230000000259 anti-tumor effect Effects 0.000 description 1
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- 235000015278 beef Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical class C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- OQUUTERJWTYTHP-UHFFFAOYSA-N butanedioate;1h-tetrazol-1-ium Chemical compound [NH2+]1C=NN=N1.[NH2+]1C=NN=N1.[O-]C(=O)CCC([O-])=O OQUUTERJWTYTHP-UHFFFAOYSA-N 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
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- DVXFDXIVWQWLIU-UHFFFAOYSA-N dehydroeburiconic acid Natural products CC1(C)C(=O)CCC2(C)C3=CCC4(C)C(C(CCC(=C)C(C)C)C(O)=O)CCC4(C)C3=CCC21 DVXFDXIVWQWLIU-UHFFFAOYSA-N 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
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- 239000003205 fragrance Substances 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 230000000762 glandular Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- ZQIOPEXWVBIZAV-ZKYCIREVSA-N lanostane Chemical group CC([C@@H]1CC2)(C)CCC[C@]1(C)[C@@H]1[C@@H]2[C@]2(C)CC[C@H]([C@H](C)CCCC(C)C)[C@@]2(C)CC1 ZQIOPEXWVBIZAV-ZKYCIREVSA-N 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- ZWMDJBNGXKAIRO-PRBDMEKXSA-N methyl antcinate H Chemical compound C([C@@]12C)C[C@@H](O)[C@@H](C)[C@@H]1CC(=O)C1=C2C(=O)[C@H](O)[C@]2(C)[C@@H]([C@H](C)CCC(=C)C(C)C(=O)OC)CC[C@H]21 ZWMDJBNGXKAIRO-PRBDMEKXSA-N 0.000 description 1
- 229930183875 methylantcinate Natural products 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 230000017066 negative regulation of growth Effects 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 230000000422 nocturnal effect Effects 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 150000003429 steroid acids Chemical class 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- DVORYMAGXQGBQK-QCMFUGJUSA-N zhankuic acid A Chemical compound C([C@@]12C)CC(=O)[C@@H](C)[C@@H]1CC(=O)C1=C2C(=O)C[C@]2(C)[C@@H]([C@@H](CCC(=C)C(C)C(O)=O)C)CC[C@H]21 DVORYMAGXQGBQK-QCMFUGJUSA-N 0.000 description 1
- TXEJUZMIQVTZHO-JNXQNPAGSA-N zhankuic acid B Chemical compound C([C@@]12C)C[C@@H](O)[C@@H](C)[C@@H]1CC(=O)C1=C2C(=O)C[C@]2(C)[C@@H]([C@@H](CCC(=C)C(C)C(O)=O)C)CC[C@H]21 TXEJUZMIQVTZHO-JNXQNPAGSA-N 0.000 description 1
- LVFHKUZOQUATIE-NIQDNRFFSA-N zhankuic acid C Chemical compound C([C@@]12C)C[C@@H](O)[C@@H](C)[C@@H]1CC(=O)C1=C2C(=O)[C@H](O)[C@]2(C)[C@@H]([C@@H](CCC(=C)C(C)C(O)=O)C)CC[C@H]21 LVFHKUZOQUATIE-NIQDNRFFSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW095140243 | 2006-10-31 | ||
| TW095140243A TW200819125A (en) | 2006-10-31 | 2006-10-31 | Application of Antrodia camphorate extract capable of inhibiting growth of tumor cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008115159A JP2008115159A (ja) | 2008-05-22 |
| JP5019946B2 true JP5019946B2 (ja) | 2012-09-05 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007127689A Expired - Fee Related JP5019946B2 (ja) | 2006-10-31 | 2007-05-14 | ベニクスノキタケ抽出物化合物の腫瘍細胞生長抑制に対する応用 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20080103195A1 (enExample) |
| JP (1) | JP5019946B2 (enExample) |
| TW (1) | TW200819125A (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2329816B1 (en) * | 2009-11-26 | 2016-04-13 | National Taiwan University | An anti-cancer active substance from antrodia camphorata, method for preparing the same and use thereof |
| US20110137050A1 (en) * | 2009-12-04 | 2011-06-09 | Yong Chun Prosperous Biotech Co. | Process for the Preparation of 4,7-Dimethoxy-5-Methyl-1,3-Benzodioxole and Derivatives Thereof |
| JP5313971B2 (ja) * | 2010-07-08 | 2013-10-09 | 優生生物科技股▲分▼有限公司 | ５−置換４，７−ジメトキシ−１，３−ベンゾジオキソール（５−Ｓｕｂｓｔｉｔｕｔｅｄ４，７−ｄｉｍｅｔｈｏｘｙ−１，３−ｂｅｎｚｏｄｉｏｘｏｌｅｓ）の結腸直腸癌（ｃｏｌｏｒｅｃｔａｌｃａｎｃｅｒ）治療用医薬品 |
| JP2013119544A (ja) * | 2011-12-09 | 2013-06-17 | Taiwan Leader Biotech Corp | ポリアセチレン化合物、それを含有する抽出物及びその応用 |
| US9480723B2 (en) * | 2013-05-02 | 2016-11-01 | Kingland Property Corporation, Ltd. | Method of preparing an extract of Antrodia cinnamomea having an elevated antcin C and zhankuic C content |
| CN105132288B (zh) * | 2014-05-29 | 2018-08-10 | 观文农业生技有限公司 | 新颖牛樟芝分离株和其培养产物 |
| TWI650120B (zh) * | 2017-07-21 | 2019-02-11 | 寶騰生醫股份有限公司 | 一種醫藥組成物用於製備治療或預防個體感染病毒之藥物的用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2521739B2 (ja) * | 1987-01-27 | 1996-08-07 | 新日本薬品株式会社 | 肝臓疾患治療剤 |
-
2006
- 2006-10-31 TW TW095140243A patent/TW200819125A/zh not_active IP Right Cessation
-
2007
- 2007-05-14 JP JP2007127689A patent/JP5019946B2/ja not_active Expired - Fee Related
- 2007-05-16 US US11/749,659 patent/US20080103195A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW200819125A (en) | 2008-05-01 |
| JP2008115159A (ja) | 2008-05-22 |
| TWI302834B (enExample) | 2008-11-11 |
| US20080103195A1 (en) | 2008-05-01 |
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