JP4874523B2 - 不正使用防止機能付きの経皮的オピオイド送給装置 - Google Patents
不正使用防止機能付きの経皮的オピオイド送給装置 Download PDFInfo
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- JP4874523B2 JP4874523B2 JP2003569151A JP2003569151A JP4874523B2 JP 4874523 B2 JP4874523 B2 JP 4874523B2 JP 2003569151 A JP2003569151 A JP 2003569151A JP 2003569151 A JP2003569151 A JP 2003569151A JP 4874523 B2 JP4874523 B2 JP 4874523B2
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- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- opioid
- delivery device
- transdermal delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 150000003839 salts Chemical class 0.000 claims abstract description 282
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- IYNWSQDZXMGGGI-NUEKZKHPSA-N 3-hydroxymorphinan Chemical compound C1CCC[C@H]2[C@H]3CC4=CC=C(O)C=C4[C@]21CCN3 IYNWSQDZXMGGGI-NUEKZKHPSA-N 0.000 claims description 2
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| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| US20040126323A1 (en) * | 2002-08-20 | 2004-07-01 | Ihor Shevchuk | Transdermal dosage form comprising an active agent and a salt and free-base form of an adverse agent |
| US8790689B2 (en) * | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| KR101159828B1 (ko) * | 2003-04-30 | 2012-07-04 | 퍼듀 퍼머 엘피 | 활성제 구성요소 및 활성제 층의 원위부에 억제제 구성요소를 포함하는 내변조성 경피제형 |
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| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US7867511B2 (en) * | 2004-01-23 | 2011-01-11 | Travanti Pharma Inc. | Abuse potential reduction in abusable substance dosage form |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
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| US9056061B2 (en) | 2005-09-23 | 2015-06-16 | Alza Corporation | Transdermal nicotine salt delivery system |
| EP1948142B1 (en) | 2005-09-23 | 2014-04-09 | ALZA Corporation | High enhancer-loading polyacrylate formulation for transdermal applications |
| US9522188B2 (en) | 2005-12-13 | 2016-12-20 | Biodelivery Sciences International, Inc. | Abuse resistant transmucosal drug delivery device |
| GB0606124D0 (en) * | 2006-03-28 | 2006-05-03 | Reckitt Benckiser Healthcare | Buprenorphine derivatives and uses thereof |
| EP2054031B1 (en) | 2006-07-21 | 2016-04-06 | BioDelivery Sciences International, Inc. | Transmucosal delivery devices with enhanced uptake |
| DE202006018609U1 (de) * | 2006-08-29 | 2007-05-16 | Euro-Celtique S.A. | Verwendung von Opioidformulierungen in nadellosen Vorrichtungen zur Medikamentenverabreichung |
| CA2663515C (en) * | 2006-09-22 | 2015-09-01 | Alltranz Inc. | Transdermally deliverable buprenorphine prodrugs and abuse-resistant compositions thereof |
| EP2249811A1 (en) | 2008-01-25 | 2010-11-17 | Grünenthal GmbH | Pharmaceutical dosage form |
| WO2009106831A2 (en) | 2008-02-28 | 2009-09-03 | Syntropharma Limited | Pharmaceutical composition |
| WO2009120889A2 (en) * | 2008-03-26 | 2009-10-01 | Alltranz Inc. | Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists |
| CN102066381A (zh) * | 2008-04-24 | 2011-05-18 | 詹森药业有限公司 | 纳美芬前药 |
| TWI630208B (zh) | 2008-12-08 | 2018-07-21 | 歐陸斯迪公司 | 二氫羥戊甲嗎啡 |
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- 2003-02-19 DE DE60320530T patent/DE60320530T2/de not_active Expired - Lifetime
- 2003-02-19 AT AT03742830T patent/ATE392892T1/de active
- 2003-02-19 DK DK03742830T patent/DK1476141T3/da active
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Also Published As
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| JP2006502967A (ja) | 2006-01-26 |
| EP1476141A2 (en) | 2004-11-17 |
| JP5453151B2 (ja) | 2014-03-26 |
| EP1476141B1 (en) | 2008-04-23 |
| ES2305480T3 (es) | 2008-11-01 |
| WO2003070191A2 (en) | 2003-08-28 |
| US20040033253A1 (en) | 2004-02-19 |
| AU2003216321A8 (en) | 2003-09-09 |
| DE60320530T2 (de) | 2009-06-10 |
| WO2003070191A3 (en) | 2004-09-10 |
| AU2003216321A1 (en) | 2003-09-09 |
| DK1476141T3 (da) | 2008-08-18 |
| DE60320530D1 (de) | 2008-06-05 |
| ATE392892T1 (de) | 2008-05-15 |
| SI1476141T1 (sl) | 2008-08-31 |
| JP2010189403A (ja) | 2010-09-02 |
| CY1108201T1 (el) | 2014-02-12 |
| JP2013237692A (ja) | 2013-11-28 |
| PT1476141E (pt) | 2008-07-03 |
| WO2003070191A8 (en) | 2004-06-10 |
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