JP4854197B2 - 流量制御方法および流量制御装置 - Google Patents
流量制御方法および流量制御装置 Download PDFInfo
- Publication number
- JP4854197B2 JP4854197B2 JP2004538456A JP2004538456A JP4854197B2 JP 4854197 B2 JP4854197 B2 JP 4854197B2 JP 2004538456 A JP2004538456 A JP 2004538456A JP 2004538456 A JP2004538456 A JP 2004538456A JP 4854197 B2 JP4854197 B2 JP 4854197B2
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- JP
- Japan
- Prior art keywords
- liquid
- flow rate
- pressure
- air
- booster
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title claims description 30
- 239000007788 liquid Substances 0.000 claims description 214
- 239000000203 mixture Substances 0.000 claims description 14
- 238000004891 communication Methods 0.000 claims description 5
- 238000003825 pressing Methods 0.000 claims description 4
- 238000004811 liquid chromatography Methods 0.000 claims description 2
- 238000007599 discharging Methods 0.000 claims 2
- 238000000926 separation method Methods 0.000 description 6
- 238000004128 high performance liquid chromatography Methods 0.000 description 5
- 238000005259 measurement Methods 0.000 description 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000002457 bidirectional effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005520 electrodynamics Effects 0.000 description 1
- 238000004401 flow injection analysis Methods 0.000 description 1
- 238000001499 laser induced fluorescence spectroscopy Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D7/00—Control of flow
- G05D7/06—Control of flow characterised by the use of electric means
- G05D7/0617—Control of flow characterised by the use of electric means specially adapted for fluid materials
- G05D7/0629—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means
- G05D7/0676—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means by action on flow sources
- G05D7/0682—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means by action on flow sources using a plurality of flow sources
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D11/00—Control of flow ratio
- G05D11/02—Controlling ratio of two or more flows of fluid or fluent material
- G05D11/13—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means
- G05D11/131—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means by measuring the values related to the quantity of the individual components
- G05D11/132—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means by measuring the values related to the quantity of the individual components by controlling the flow of the individual components
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D7/00—Control of flow
- G05D7/06—Control of flow characterised by the use of electric means
- G05D7/0617—Control of flow characterised by the use of electric means specially adapted for fluid materials
- G05D7/0629—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means
- G05D7/0694—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means by action on throttling means or flow sources of very small size, e.g. microfluidics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
- G01N2030/324—Control of physical parameters of the fluid carrier of pressure or speed speed, flow rate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
- G01N2030/326—Control of physical parameters of the fluid carrier of pressure or speed pumps
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Automation & Control Theory (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Flow Control (AREA)
- Measuring Volume Flow (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/246,284 | 2002-09-17 | ||
| US10/246,284 US7465382B2 (en) | 2001-06-13 | 2002-09-17 | Precision flow control system |
| PCT/US2003/030008 WO2004027535A1 (en) | 2002-09-17 | 2003-09-17 | Flow control system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005539329A JP2005539329A (ja) | 2005-12-22 |
| JP2005539329A5 JP2005539329A5 (enExample) | 2006-12-14 |
| JP4854197B2 true JP4854197B2 (ja) | 2012-01-18 |
Family
ID=32028952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004538456A Expired - Fee Related JP4854197B2 (ja) | 2002-09-17 | 2003-09-17 | 流量制御方法および流量制御装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7465382B2 (enExample) |
| EP (1) | EP1540437B1 (enExample) |
| JP (1) | JP4854197B2 (enExample) |
| AU (1) | AU2003275188A1 (enExample) |
| CA (1) | CA2498034C (enExample) |
| WO (1) | WO2004027535A1 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020189947A1 (en) * | 2001-06-13 | 2002-12-19 | Eksigent Technologies Llp | Electroosmotic flow controller |
| US20030098661A1 (en) * | 2001-11-29 | 2003-05-29 | Ken Stewart-Smith | Control system for vehicle seats |
| CA2490876A1 (en) * | 2002-07-05 | 2004-02-19 | Gaspardo Seminatrici S.P.A. | A volumetric metering device for the metered delivery of granular and powdery materials, particularly for machines for distributing the said materials |
| US7364647B2 (en) * | 2002-07-17 | 2008-04-29 | Eksigent Technologies Llc | Laminated flow device |
| US7517440B2 (en) * | 2002-07-17 | 2009-04-14 | Eksigent Technologies Llc | Electrokinetic delivery systems, devices and methods |
| US7235164B2 (en) * | 2002-10-18 | 2007-06-26 | Eksigent Technologies, Llc | Electrokinetic pump having capacitive electrodes |
| US6962658B2 (en) * | 2003-05-20 | 2005-11-08 | Eksigent Technologies, Llc | Variable flow rate injector |
| US20060186028A1 (en) * | 2004-02-06 | 2006-08-24 | Micromass Uk Limited | Mass spectrometer |
| US7559356B2 (en) * | 2004-04-19 | 2009-07-14 | Eksident Technologies, Inc. | Electrokinetic pump driven heat transfer system |
| WO2005113457A2 (en) | 2004-05-21 | 2005-12-01 | Waters Investments Limited | Closed loop flow control of a hplc constant flow pump to enable low-flow operation |
| GB2454783B (en) * | 2004-05-21 | 2009-10-28 | Waters Investments Ltd | HPLC constant flow pump to enable low-flow operation, wherein thermal-based sensors are contained within an isothermal block |
| GB2446321B8 (en) * | 2004-07-13 | 2011-03-02 | Waters Investments Ltd | High pressure pump controller. |
| US7670480B2 (en) * | 2005-03-31 | 2010-03-02 | Agilent Technologies, Inc. | Solvent supply with correction of piston movement |
| EP1707958B1 (en) * | 2005-03-31 | 2011-01-19 | Agilent Technologies, Inc. | Device and method for solvent supply with correction of piston movement |
| US7448553B2 (en) * | 2005-04-19 | 2008-11-11 | Masco Corporation Of Indiana | Fluid mixer |
| US7458520B2 (en) * | 2005-04-19 | 2008-12-02 | Masco Corporation Of Indiana | Electronic proportioning valve |
| US7475827B2 (en) * | 2005-04-19 | 2009-01-13 | Masco Corporation Of Indiana | Fluid mixer |
| US7584898B2 (en) | 2005-07-01 | 2009-09-08 | Masco Corporation Of Indiana | Manual override for electronic proportioning valve |
| WO2007030755A2 (en) * | 2005-09-09 | 2007-03-15 | Eksigent Technologies, Llc | Variable flow rate system for column chromatography |
| KR100697292B1 (ko) * | 2005-10-04 | 2007-03-20 | 삼성전자주식회사 | 반도체 장치 및 그 형성 방법 |
| WO2007062068A2 (en) * | 2005-11-23 | 2007-05-31 | Deon Anex, Llp | Electrokinetic pump designs and drug delivery systems |
| EP1996303B1 (en) * | 2006-03-17 | 2018-05-02 | Waters Technologies Corporation | Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients |
| US7516658B2 (en) | 2006-09-29 | 2009-04-14 | Rosemount Inc. | Electro-kinetic pressure/flow sensor |
| US7867592B2 (en) | 2007-01-30 | 2011-01-11 | Eksigent Technologies, Inc. | Methods, compositions and devices, including electroosmotic pumps, comprising coated porous surfaces |
| WO2009076134A1 (en) * | 2007-12-11 | 2009-06-18 | Eksigent Technologies, Llc | Electrokinetic pump with fixed stroke volume |
| EP2249939B1 (en) * | 2008-02-06 | 2017-05-10 | Proseon Biosystems A/S | Flow control in high performance liquid chromatography |
| US8794052B2 (en) * | 2009-04-16 | 2014-08-05 | Shimadzu Corporation | Liquid chromatograph |
| US8746270B2 (en) * | 2010-02-10 | 2014-06-10 | Brg Industries Incorporated | Precision low flow rate fluid delivery system and methods for controlling same |
| WO2011162666A1 (en) * | 2010-06-23 | 2011-12-29 | Ge Healthcare Bio-Sciences Ab | Method of preparing liquid mixtures |
| US8550794B2 (en) * | 2010-08-09 | 2013-10-08 | Foothill Land, Llc | Double acting fluid pump |
| US8729502B1 (en) | 2010-10-28 | 2014-05-20 | The Research Foundation For The State University Of New York | Simultaneous, single-detector fluorescence detection of multiple analytes with frequency-specific lock-in detection |
| EP2704759A4 (en) | 2011-05-05 | 2015-06-03 | Eksigent Technologies Llc | COUPLING GEL FOR ELECTROCINETIC FLUID DISTRIBUTION SYSTEMS |
| US20120282112A1 (en) * | 2011-05-05 | 2012-11-08 | Nip Kenneth Kei-Ho | Ganging electrokinetic pumps |
| US9459239B2 (en) | 2011-07-08 | 2016-10-04 | Agilent Technologies, Inc. | Intake monitoring for accurate proportioning |
| EP2626697B1 (en) | 2012-02-07 | 2018-10-31 | King Saud University | Liquid chromatography device |
| WO2015095590A1 (en) * | 2013-12-18 | 2015-06-25 | Eksigent Technologies Llc | System and method of control of a reciprocating electrokinetic pump |
| US9816971B2 (en) * | 2014-09-08 | 2017-11-14 | Waters Technologies Corporation | Controllable injector sample dilution for a liquid chromatography system |
| US9416777B2 (en) | 2014-09-26 | 2016-08-16 | Becton, Dickinson And Company | Control circuits for electrochemical pump with E-valves |
| US9664659B2 (en) * | 2014-11-05 | 2017-05-30 | Dresser, Inc. | Apparatus and method for testing gas meters |
| GB2538103B (en) * | 2015-05-08 | 2021-09-15 | Agilent Technologies Inc | Correcting sample metering inaccuracy due to thermally induced volume change in sample separation apparatus |
| US20170074256A1 (en) * | 2015-09-16 | 2017-03-16 | William Banko | Bi-Metallic Solar Water Filtration Pump |
| US10814062B2 (en) | 2017-08-31 | 2020-10-27 | Becton, Dickinson And Company | Reservoir with low volume sensor |
| JP6851953B2 (ja) * | 2017-10-30 | 2021-03-31 | アークレイ株式会社 | ポンプ駆動方法 |
| US11835975B2 (en) * | 2020-04-29 | 2023-12-05 | Univesal City Studios LLC | Multi-stage water effect system |
| CN113668019B (zh) * | 2021-08-31 | 2022-05-13 | 广东嘉元科技股份有限公司 | 一种电解铜箔设备精密配液装置 |
| EP4416567B1 (en) * | 2021-10-14 | 2025-03-12 | Ovizio Imaging Systems NV/SA | Method for monitoring a liquid culture flow |
| CN116422222B (zh) * | 2023-06-13 | 2023-09-01 | 福建德尔科技股份有限公司 | 一种氟气氮气自动混合的流量控制系统 |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50116893A (enExample) * | 1974-02-28 | 1975-09-12 | ||
| JPS6454220A (en) * | 1987-08-26 | 1989-03-01 | Hitachi Ltd | Small laminar flowmeter |
| JPS6468503A (en) * | 1987-09-07 | 1989-03-14 | Uni Charm Corp | Disposable diaper |
| JPH0719201A (ja) * | 1993-07-05 | 1995-01-20 | Shimadzu Corp | 高液圧発生装置 |
| JPH0772934A (ja) * | 1991-07-29 | 1995-03-17 | Asahi Breweries Ltd | インライン混合制御装置 |
| JPH07306192A (ja) * | 1994-05-12 | 1995-11-21 | T H I Syst Kk | 分取用液体クロマトグラフィ装置 |
| JP2000292227A (ja) * | 1999-04-06 | 2000-10-20 | Advance Denki Kogyo Kk | 流量測定方法および流量測定装置 |
| JP2001183193A (ja) * | 1999-12-27 | 2001-07-06 | Seiko Epson Corp | 流量測定装置及びこれを用いた薬液供給装置 |
| JP2002529235A (ja) * | 1998-11-12 | 2002-09-10 | アリゾナ ボード オブ リージェンツ | 極微量流を制御するための実用装置 |
| JP2003513255A (ja) * | 1999-10-29 | 2003-04-08 | ウォーターズ・インヴェストメンツ・リミテッド | 高圧キャピラリ液体クロマトグラフィ溶媒送出システム |
Family Cites Families (99)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2615940A (en) * | 1949-10-25 | 1952-10-28 | Williams Milton | Electrokinetic transducing method and apparatus |
| US2644902A (en) * | 1951-11-27 | 1953-07-07 | Jr Edward V Hardway | Electrokinetic device and electrode arrangement therefor |
| US2661430A (en) * | 1951-11-27 | 1953-12-01 | Jr Edward V Hardway | Electrokinetic measuring instrument |
| US2644900A (en) * | 1951-11-27 | 1953-07-07 | Jr Edward V Hardway | Electrokinetic device |
| US2995714A (en) * | 1955-07-13 | 1961-08-08 | Kenneth W Hannah | Electrolytic oscillator |
| CA662714A (en) * | 1958-11-28 | 1963-05-07 | Union Carbide Corporation | Electro-osmotic cell |
| CA692504A (en) * | 1960-04-22 | 1964-08-11 | N. Estes Nelson | Electro-osmotic integrator |
| GB1122586A (en) * | 1964-09-02 | 1968-08-07 | Mack Gordon | Electro-hydraulic transducer |
| US3544237A (en) * | 1968-12-19 | 1970-12-01 | Dornier System Gmbh | Hydraulic regulating device |
| US3682239A (en) * | 1971-02-25 | 1972-08-08 | Momtaz M Abu Romia | Electrokinetic heat pipe |
| US3917531A (en) * | 1974-02-11 | 1975-11-04 | Spectra Physics | Flow rate feedback control chromatograph |
| US3923426A (en) * | 1974-08-15 | 1975-12-02 | Alza Corp | Electroosmotic pump and fluid dispenser including same |
| US3921041A (en) * | 1975-02-24 | 1975-11-18 | American Radionic | Dual capacitor |
| US4347131A (en) * | 1981-04-28 | 1982-08-31 | Robert Brownlee | Liquid chromatographic pump module |
| US5040126A (en) * | 1981-09-09 | 1991-08-13 | Isco, Inc. | Method for predicting steady-state conditions |
| US4638444A (en) * | 1983-02-17 | 1987-01-20 | Chemical Data Systems, Inc. | Microprocessor-controlled back-pressure system for small volume chemical analysis applications |
| GB8330107D0 (en) | 1983-11-11 | 1983-12-21 | Cosworth Eng Ltd | Transferring liquid |
| DE3577750D1 (de) | 1984-10-18 | 1990-06-21 | Hewlett Packard Gmbh | Verfahren zur behandlung einer fluessigkeit in einem rohr. |
| JPS61237717A (ja) | 1985-04-15 | 1986-10-23 | Nippon Kokudo Kaihatsu Kk | 薬液の自然浸透工法およびこの方法を実施するためのプラント |
| US4681678A (en) * | 1986-10-10 | 1987-07-21 | Combustion Engineering, Inc. | Sample dilution system for supercritical fluid chromatography |
| US4684465A (en) * | 1986-10-10 | 1987-08-04 | Combustion Engineering, Inc. | Supercritical fluid chromatograph with pneumatically controlled pump |
| US4922852A (en) * | 1986-10-30 | 1990-05-08 | Nordson Corporation | Apparatus for dispensing fluid materials |
| US4810392A (en) * | 1987-04-17 | 1989-03-07 | W. R. Grace & Co. | Sample dispensing system for liquid chromatography |
| US4767279A (en) * | 1987-06-02 | 1988-08-30 | Millipore Corporation | Fluid composition and volumetric delivery control |
| JPH063354B2 (ja) * | 1987-06-23 | 1994-01-12 | アクトロニクス株式会社 | ル−プ型細管ヒ−トパイプ |
| JPH0168503U (enExample) * | 1987-10-23 | 1989-05-02 | ||
| CA1303943C (en) * | 1989-02-03 | 1992-06-23 | Robert A. Geiger | Catch flow restrictor |
| US5249929A (en) * | 1989-08-11 | 1993-10-05 | The Dow Chemical Company | Liquid chromatographic pump |
| US5635070A (en) * | 1990-07-13 | 1997-06-03 | Isco, Inc. | Apparatus and method for supercritical fluid extraction |
| US5219020A (en) * | 1990-11-22 | 1993-06-15 | Actronics Kabushiki Kaisha | Structure of micro-heat pipe |
| JPH0529938A (ja) | 1991-07-18 | 1993-02-05 | Sony Corp | 制御装置 |
| US5312233A (en) * | 1992-02-25 | 1994-05-17 | Ivek Corporation | Linear liquid dispensing pump for dispensing liquid in nanoliter volumes |
| US5630706A (en) * | 1992-03-05 | 1997-05-20 | Yang; Frank J. | Multichannel pump apparatus with microflow rate capability |
| US5664938A (en) * | 1992-03-05 | 1997-09-09 | Yang; Frank Jiann-Fu | Mixing apparatus for microflow gradient pumping |
| JPH0618964A (ja) | 1992-06-30 | 1994-01-28 | Canon Inc | 撮影装置、カメラ及び微調整機構 |
| US5429728A (en) * | 1992-08-31 | 1995-07-04 | Hewlett-Packard Company | Electroosmotic flow control using back pressure in capillary electrophoresis |
| US5302264A (en) * | 1992-09-02 | 1994-04-12 | Scientronix, Inc. | Capillary eletrophoresis method and apparatus |
| US5482608A (en) * | 1993-01-19 | 1996-01-09 | Hewlett Packard Company | Capillary electrophoresis flow control system |
| DE59307434D1 (de) * | 1993-07-20 | 1997-10-30 | Sulzer Hexis Ag | Zentralsymmetrische Brennstoffzellenbatterie |
| US5573651A (en) * | 1995-04-17 | 1996-11-12 | The Dow Chemical Company | Apparatus and method for flow injection analysis |
| WO1996039252A1 (en) | 1995-06-06 | 1996-12-12 | David Sarnoff Research Center, Inc. | Electrokinetic pumping |
| DE19625648A1 (de) | 1995-07-28 | 1997-01-30 | Hewlett Packard Co | Pumpsystem |
| FR2738613B1 (fr) * | 1995-09-08 | 1997-10-24 | Thomson Csf | Procede d'asservissement d'une servovalve hydraulique pouvant etre asservie en debit et en pression |
| US6045933A (en) * | 1995-10-11 | 2000-04-04 | Honda Giken Kogyo Kabushiki Kaisha | Method of supplying fuel gas to a fuel cell |
| JPH09281077A (ja) | 1996-04-16 | 1997-10-31 | Hitachi Ltd | キャピラリ−電気泳動装置 |
| US6280967B1 (en) * | 1996-08-02 | 2001-08-28 | Axiom Biotechnologies, Inc. | Cell flow apparatus and method for real-time of cellular responses |
| US5814742A (en) * | 1996-10-11 | 1998-09-29 | L C Packings, Nederland B.V. | Fully automated micro-autosampler for micro, capillary and nano high performance liquid chromatography |
| US5797719A (en) * | 1996-10-30 | 1998-08-25 | Supercritical Fluid Technologies, Inc. | Precision high pressure control assembly |
| US5888050A (en) * | 1996-10-30 | 1999-03-30 | Supercritical Fluid Technologies, Inc. | Precision high pressure control assembly |
| US5670707A (en) * | 1996-11-01 | 1997-09-23 | Varian Associates, Inc. | Calibration method for a chromatography column |
| US5961800A (en) * | 1997-05-08 | 1999-10-05 | Sarnoff Corporation | Indirect electrode-based pumps |
| US6106685A (en) * | 1997-05-13 | 2000-08-22 | Sarnoff Corporation | Electrode combinations for pumping fluids |
| US5942093A (en) * | 1997-06-18 | 1999-08-24 | Sandia Corporation | Electro-osmotically driven liquid delivery method and apparatus |
| US6019882A (en) * | 1997-06-25 | 2000-02-01 | Sandia Corporation | Electrokinetic high pressure hydraulic system |
| US6277257B1 (en) * | 1997-06-25 | 2001-08-21 | Sandia Corporation | Electrokinetic high pressure hydraulic system |
| US6013164A (en) * | 1997-06-25 | 2000-01-11 | Sandia Corporation | Electokinetic high pressure hydraulic system |
| US6001231A (en) * | 1997-07-15 | 1999-12-14 | Caliper Technologies Corp. | Methods and systems for monitoring and controlling fluid flow rates in microfluidic systems |
| US6221332B1 (en) * | 1997-08-05 | 2001-04-24 | Microfluidics International Corp. | Multiple stream high pressure mixer/reactor |
| US6004443A (en) * | 1997-08-13 | 1999-12-21 | Rhodes; Percy H. | Chromatography-format fluid electrophoresis |
| JP3430879B2 (ja) | 1997-09-19 | 2003-07-28 | トヨタ自動車株式会社 | 内燃機関の排気浄化装置 |
| US6012902A (en) * | 1997-09-25 | 2000-01-11 | Caliper Technologies Corp. | Micropump |
| US6139734A (en) * | 1997-10-20 | 2000-10-31 | University Of Virginia Patent Foundation | Apparatus for structural characterization of biological moieties through HPLC separation |
| US6068243A (en) * | 1998-01-05 | 2000-05-30 | A & B Plastics, Inc. | Self-locking, adjustable-width slat for chain link fences |
| US6167910B1 (en) * | 1998-01-20 | 2001-01-02 | Caliper Technologies Corp. | Multi-layer microfluidic devices |
| US6224728B1 (en) * | 1998-04-07 | 2001-05-01 | Sandia Corporation | Valve for fluid control |
| US5997746A (en) * | 1998-05-29 | 1999-12-07 | New Objective Inc. | Evaporative packing of capillary columns |
| WO1999067639A1 (en) | 1998-06-25 | 1999-12-29 | Caliper Technologies Corporation | High throughput methods, systems and apparatus for performing cell based screening assays |
| EP1098594B1 (en) | 1998-07-21 | 2007-12-12 | SPECTRX, Inc. | System and method for continuous analyte monitoring |
| US6086243A (en) | 1998-10-01 | 2000-07-11 | Sandia Corporation | Electrokinetic micro-fluid mixer |
| US6068767A (en) * | 1998-10-29 | 2000-05-30 | Sandia Corporation | Device to improve detection in electro-chromatography |
| US6416642B1 (en) | 1999-01-21 | 2002-07-09 | Caliper Technologies Corp. | Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection |
| US6428666B1 (en) * | 1999-02-22 | 2002-08-06 | Sandia National Laboratories | Electrokinetic concentration of charged molecules |
| US6477410B1 (en) * | 2000-05-31 | 2002-11-05 | Biophoretic Therapeutic Systems, Llc | Electrokinetic delivery of medicaments |
| US6270641B1 (en) | 1999-04-26 | 2001-08-07 | Sandia Corporation | Method and apparatus for reducing sample dispersion in turns and junctions of microchannel systems |
| US6846399B2 (en) * | 1999-05-12 | 2005-01-25 | Sandia National Laboratories | Castable three-dimensional stationary phase for electric field-driven applications |
| US6406605B1 (en) * | 1999-06-01 | 2002-06-18 | Ysi Incorporated | Electroosmotic flow controlled microfluidic devices |
| US6255551B1 (en) * | 1999-06-04 | 2001-07-03 | General Electric Company | Method and system for treating contaminated media |
| US6287440B1 (en) | 1999-06-18 | 2001-09-11 | Sandia Corporation | Method for eliminating gas blocking in electrokinetic pumping systems |
| US6386050B1 (en) * | 1999-12-21 | 2002-05-14 | Agilent Technologies, Inc. | Non-invasive fluid flow sensing based on injected heat tracers and indirect temperature monitoring |
| US6824900B2 (en) * | 2002-03-04 | 2004-11-30 | Mti Microfuel Cells Inc. | Method and apparatus for water management of a fuel cell system |
| US6290909B1 (en) * | 2000-04-13 | 2001-09-18 | Sandia Corporation | Sample injector for high pressure liquid chromatography |
| US6460420B1 (en) * | 2000-04-13 | 2002-10-08 | Sandia National Laboratories | Flowmeter for pressure-driven chromatography systems |
| US20020022802A1 (en) | 2000-06-13 | 2002-02-21 | Simpson Frank B. | Wrap spring clutch syringe ram and frit mixer |
| US6289914B1 (en) * | 2000-08-16 | 2001-09-18 | Novartis Ag | Microflow splitter |
| DE10040084A1 (de) * | 2000-08-16 | 2002-03-07 | Siemens Ag | Verfahren zur Mischung von Brennstoff in Wasser, zugehörige Vorrichtung und Verwendung dieser Vorrichtung |
| JP3764421B2 (ja) | 2000-10-03 | 2006-04-05 | ダイオネックス コーポレイション | 液体クロマトグラフィ−質量分析計(lc−ms)分析におけるピークパーキングのための方法及びシステム |
| US6402946B1 (en) * | 2000-10-26 | 2002-06-11 | Bruker Analytik Gmbh | Device for feeding a chromatography flow |
| EP1331997B1 (en) * | 2000-11-06 | 2004-06-16 | Nanostream, Inc. | Microfluidic flow control devices |
| US6805783B2 (en) * | 2000-12-13 | 2004-10-19 | Toyo Technologies, Inc. | Method for manipulating a solution using a ferroelectric electro-osmotic pump |
| US6497975B2 (en) * | 2000-12-15 | 2002-12-24 | Motorola, Inc. | Direct methanol fuel cell including integrated flow field and method of fabrication |
| US7070681B2 (en) * | 2001-01-24 | 2006-07-04 | The Board Of Trustees Of The Leland Stanford Junior University | Electrokinetic instability micromixer |
| WO2002069016A2 (en) | 2001-02-28 | 2002-09-06 | Lightwave Microsystems Corporation | Microfluid control for waveguide optical switches, variable attenuators, and other optical devices |
| US6404193B1 (en) * | 2001-04-09 | 2002-06-11 | Waters Investments Limited | Solvent susceptibility compensation for coupled LC-NMR |
| US20020189947A1 (en) * | 2001-06-13 | 2002-12-19 | Eksigent Technologies Llp | Electroosmotic flow controller |
| US6766817B2 (en) * | 2001-07-25 | 2004-07-27 | Tubarc Technologies, Llc | Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action |
| US6719535B2 (en) * | 2002-01-31 | 2004-04-13 | Eksigent Technologies, Llc | Variable potential electrokinetic device |
| JP3637392B2 (ja) * | 2002-04-08 | 2005-04-13 | 独立行政法人産業技術総合研究所 | 燃料電池 |
| US7364647B2 (en) | 2002-07-17 | 2008-04-29 | Eksigent Technologies Llc | Laminated flow device |
| US20040107996A1 (en) * | 2002-12-09 | 2004-06-10 | Crocker Robert W. | Variable flow control apparatus |
-
2002
- 2002-09-17 US US10/246,284 patent/US7465382B2/en not_active Expired - Lifetime
-
2003
- 2003-09-17 AU AU2003275188A patent/AU2003275188A1/en not_active Abandoned
- 2003-09-17 CA CA2498034A patent/CA2498034C/en not_active Expired - Lifetime
- 2003-09-17 JP JP2004538456A patent/JP4854197B2/ja not_active Expired - Fee Related
- 2003-09-17 EP EP03759457.9A patent/EP1540437B1/en not_active Expired - Lifetime
- 2003-09-17 WO PCT/US2003/030008 patent/WO2004027535A1/en not_active Ceased
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50116893A (enExample) * | 1974-02-28 | 1975-09-12 | ||
| JPS6454220A (en) * | 1987-08-26 | 1989-03-01 | Hitachi Ltd | Small laminar flowmeter |
| JPS6468503A (en) * | 1987-09-07 | 1989-03-14 | Uni Charm Corp | Disposable diaper |
| JPH0772934A (ja) * | 1991-07-29 | 1995-03-17 | Asahi Breweries Ltd | インライン混合制御装置 |
| JPH0719201A (ja) * | 1993-07-05 | 1995-01-20 | Shimadzu Corp | 高液圧発生装置 |
| JPH07306192A (ja) * | 1994-05-12 | 1995-11-21 | T H I Syst Kk | 分取用液体クロマトグラフィ装置 |
| JP2002529235A (ja) * | 1998-11-12 | 2002-09-10 | アリゾナ ボード オブ リージェンツ | 極微量流を制御するための実用装置 |
| JP2000292227A (ja) * | 1999-04-06 | 2000-10-20 | Advance Denki Kogyo Kk | 流量測定方法および流量測定装置 |
| JP2003513255A (ja) * | 1999-10-29 | 2003-04-08 | ウォーターズ・インヴェストメンツ・リミテッド | 高圧キャピラリ液体クロマトグラフィ溶媒送出システム |
| JP2001183193A (ja) * | 1999-12-27 | 2001-07-06 | Seiko Epson Corp | 流量測定装置及びこれを用いた薬液供給装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| US7465382B2 (en) | 2008-12-16 |
| WO2004027535A1 (en) | 2004-04-01 |
| EP1540437A1 (en) | 2005-06-15 |
| JP2005539329A (ja) | 2005-12-22 |
| CA2498034A1 (en) | 2004-04-01 |
| EP1540437B1 (en) | 2013-11-06 |
| US20030052007A1 (en) | 2003-03-20 |
| CA2498034C (en) | 2012-07-10 |
| AU2003275188A1 (en) | 2004-04-08 |
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