JP4845165B2 - 男性におけるテストステロン欠損の処置のための方法および物質 - Google Patents

男性におけるテストステロン欠損の処置のための方法および物質 Download PDF

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JP4845165B2
JP4845165B2 JP2003511763A JP2003511763A JP4845165B2 JP 4845165 B2 JP4845165 B2 JP 4845165B2 JP 2003511763 A JP2003511763 A JP 2003511763A JP 2003511763 A JP2003511763 A JP 2003511763A JP 4845165 B2 JP4845165 B2 JP 4845165B2
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testosterone
clomiphene
composition
trans
levels
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JP2005520779A (ja
JP2005520779A5 (es
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ジョセフ エス． ポドルスキー，
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リプロス セラピューティクス インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2003511763A 2001-07-09 2002-07-09 男性におけるテストステロン欠損の処置のための方法および物質 Expired - Fee Related JP4845165B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30431301P 2001-07-09 2001-07-09
US60/304,313 2001-07-09
PCT/US2002/021524 WO2003005954A2 (en) 2001-07-09 2002-07-09 Methods and materials for the treatment of testosterone deficiency in men

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009204154A Division JP2009280623A (ja) 2001-07-09 2009-09-03 男性におけるテストステロン欠損の処置のための方法および物質

Publications (3)

Publication Number Publication Date
JP2005520779A JP2005520779A (ja) 2005-07-14
JP2005520779A5 JP2005520779A5 (es) 2006-01-05
JP4845165B2 true JP4845165B2 (ja) 2011-12-28

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JP2003511763A Expired - Fee Related JP4845165B2 (ja) 2001-07-09 2002-07-09 男性におけるテストステロン欠損の処置のための方法および物質
JP2009204154A Withdrawn JP2009280623A (ja) 2001-07-09 2009-09-03 男性におけるテストステロン欠損の処置のための方法および物質

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JP2009204154A Withdrawn JP2009280623A (ja) 2001-07-09 2009-09-03 男性におけるテストステロン欠損の処置のための方法および物質

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US (6) US7759360B2 (es)
EP (1) EP1411916B1 (es)
JP (2) JP4845165B2 (es)
KR (1) KR100851648B1 (es)
CN (2) CN1954807A (es)
AT (1) ATE406153T1 (es)
AU (1) AU2002318225B2 (es)
BR (1) BR0211067A (es)
CA (2) CA2453337C (es)
CL (1) CL2004000026A1 (es)
CO (1) CO5550428A2 (es)
CY (1) CY1108563T1 (es)
DE (1) DE60228583D1 (es)
DK (1) DK1411916T3 (es)
EC (1) ECSP044937A (es)
ES (1) ES2312593T3 (es)
HK (1) HK1071521A1 (es)
MX (1) MXPA04000097A (es)
NZ (2) NZ551013A (es)
PL (1) PL211339B1 (es)
PT (1) PT1411916E (es)
RU (1) RU2297218C2 (es)
WO (1) WO2003005954A2 (es)
ZA (1) ZA200400142B (es)

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MX2007000050A (es) * 2004-07-14 2007-07-10 Repros Therapeutics Inc Trans-clomifeno para el tratamiento de hipertrofia de prostata benigna, cancer de prostata, hipogonadismo, trigliceridos elevados y colesterol elevado.
CA2595363C (en) * 2005-02-04 2012-03-27 Repros Therapeutics Inc. Methods and materials with trans-clomiphene for the treatment of male infertility
US8247456B2 (en) * 2005-03-22 2012-08-21 Repros Therapeutics Inc. Dosing regimes for trans-clomiphene
US20080312239A1 (en) * 2007-06-13 2008-12-18 Quatrx Pharmaceuticals Company Methods for the treatment of erectile dysfunction using fispemifene
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US20090215738A1 (en) * 2008-02-26 2009-08-27 Michael Charles Scally Prevention and treatment of an increase in cardiovascular risk, adverse cardiovascular events, infertility, and adverse psychological effects after androgen or gnrh analogue intake
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Publication number Publication date
KR20040013131A (ko) 2004-02-11
RU2004100535A (ru) 2005-06-10
KR100851648B1 (ko) 2008-08-13
US20040097597A1 (en) 2004-05-20
US7368480B2 (en) 2008-05-06
JP2005520779A (ja) 2005-07-14
EP1411916A4 (en) 2005-08-17
CY1108563T1 (el) 2014-04-09
ZA200400142B (en) 2006-02-22
US7759360B2 (en) 2010-07-20
CN1289075C (zh) 2006-12-13
US20160354325A1 (en) 2016-12-08
ECSP044937A (es) 2004-04-28
CN1551765A (zh) 2004-12-01
HK1071521A1 (en) 2005-07-22
NZ530491A (en) 2007-08-31
CA2453337C (en) 2012-08-28
EP1411916B1 (en) 2008-08-27
CA2453337A1 (en) 2003-01-23
JP2009280623A (ja) 2009-12-03
NZ551013A (en) 2008-04-30
US20140093560A1 (en) 2014-04-03
US20150265553A1 (en) 2015-09-24
US20100286281A1 (en) 2010-11-11
PL374121A1 (en) 2005-10-03
WO2003005954A2 (en) 2003-01-23
PT1411916E (pt) 2008-12-10
BR0211067A (pt) 2006-10-31
ES2312593T3 (es) 2009-03-01
CA2777199A1 (en) 2003-01-23
US8618176B2 (en) 2013-12-31
CL2004000026A1 (es) 2005-02-04
CO5550428A2 (es) 2005-08-31
WO2003005954A3 (en) 2003-10-23
CN1954807A (zh) 2007-05-02
US20040241224A1 (en) 2004-12-02
US10561624B2 (en) 2020-02-18
EP1411916A2 (en) 2004-04-28
RU2297218C2 (ru) 2007-04-20
PL211339B1 (pl) 2012-05-31
AU2002318225B2 (en) 2007-12-13
MXPA04000097A (es) 2004-05-21
DK1411916T3 (da) 2008-12-15
WO2003005954B1 (en) 2003-12-04
DE60228583D1 (de) 2008-10-09
ATE406153T1 (de) 2008-09-15

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