BR0211067A - métodos e materiais para o tratamento de deficiência de testosterona em homens - Google Patents

métodos e materiais para o tratamento de deficiência de testosterona em homens

Info

Publication number
BR0211067A
BR0211067A BRPI0211067-9A BR0211067A BR0211067A BR 0211067 A BR0211067 A BR 0211067A BR 0211067 A BR0211067 A BR 0211067A BR 0211067 A BR0211067 A BR 0211067A
Authority
BR
Brazil
Prior art keywords
methods
men
treatment
materials
testosterone deficiency
Prior art date
Application number
BRPI0211067-9A
Other languages
English (en)
Inventor
Joseph Podolski
Original Assignee
Zonagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23175972&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0211067(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zonagen Inc filed Critical Zonagen Inc
Publication of BR0211067A publication Critical patent/BR0211067A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"MéTODOS E MATERIAIS PARA O TRATAMENTO DE DEFICIêNCIA DE TESTOSTERONA EM HOMENS". A presente invenção refere-se o uso de composições compreendendo trans-clomifeno para tratar homens com hipogonadismo. A invenção é também direcionada a métodos para tratar machos com hipogonadismo.
BRPI0211067-9A 2001-07-09 2002-07-09 métodos e materiais para o tratamento de deficiência de testosterona em homens BR0211067A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30431301P 2001-07-09 2001-07-09
PCT/US2002/021524 WO2003005954A2 (en) 2001-07-09 2002-07-09 Methods and materials for the treatment of testosterone deficiency in men

Publications (1)

Publication Number Publication Date
BR0211067A true BR0211067A (pt) 2006-10-31

Family

ID=23175972

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0211067-9A BR0211067A (pt) 2001-07-09 2002-07-09 métodos e materiais para o tratamento de deficiência de testosterona em homens

Country Status (24)

Country Link
US (6) US7759360B2 (pt)
EP (1) EP1411916B1 (pt)
JP (2) JP4845165B2 (pt)
KR (1) KR100851648B1 (pt)
CN (2) CN1954807A (pt)
AT (1) ATE406153T1 (pt)
AU (1) AU2002318225B2 (pt)
BR (1) BR0211067A (pt)
CA (2) CA2777199A1 (pt)
CL (1) CL2004000026A1 (pt)
CO (1) CO5550428A2 (pt)
CY (1) CY1108563T1 (pt)
DE (1) DE60228583D1 (pt)
DK (1) DK1411916T3 (pt)
EC (1) ECSP044937A (pt)
ES (1) ES2312593T3 (pt)
HK (1) HK1071521A1 (pt)
MX (1) MXPA04000097A (pt)
NZ (2) NZ551013A (pt)
PL (1) PL211339B1 (pt)
PT (1) PT1411916E (pt)
RU (1) RU2297218C2 (pt)
WO (1) WO2003005954A2 (pt)
ZA (1) ZA200400142B (pt)

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US7173064B2 (en) 2001-07-09 2007-02-06 Repros Therapeutics Inc. Methods and compositions with trans-clomiphene for treating wasting and lipodystrophy
CA2777199A1 (en) 2001-07-09 2003-01-23 Repros Therapeutics Inc. Methods and materials for the treatment of testosterone deficiency in men
EP1776098A1 (en) * 2004-07-14 2007-04-25 Repros Therapeutics Inc. Trans-clomiphene for the treatment of benign prostate hypertrophy, prostate cancer, hypogonadism, elevated triglycerides and high cholesterol
EP1848416A4 (en) * 2005-02-04 2008-09-24 Repros Therapeutics Inc METHOD AND MATERIALS USING TRANS-CLOMIPHES FOR TREATING MALE INACCURIBILITY
PL383444A1 (pl) * 2005-03-22 2008-03-17 Repros Therapeutics Inc. Sposoby dawkowania trans-klomifenu
WO2008157335A2 (en) * 2007-06-13 2008-12-24 Quatrx Pharmaceuticals Company Methods for the treatment of erectile dysfunction using fispemifene
US20110118355A1 (en) * 2007-09-21 2011-05-19 Harry Fisch Treatment of migraine headaches using antiestrogens
CN102940619A (zh) 2007-10-16 2013-02-27 利普生物药剂公司 用于治疗代谢综合征的珠氯米芬
WO2009052377A1 (en) * 2007-10-18 2009-04-23 Harry Fisch Treatment of migraine headaches using antiestrogens
US20090215738A1 (en) * 2008-02-26 2009-08-27 Michael Charles Scally Prevention and treatment of an increase in cardiovascular risk, adverse cardiovascular events, infertility, and adverse psychological effects after androgen or gnrh analogue intake
TWI477276B (zh) 2008-04-28 2015-03-21 Repros Therapeutics Inc 抗黃體素給藥方案
RU2474424C2 (ru) * 2010-09-24 2013-02-10 Государственное образовательное учреждение высшего профессионального образования "Ивановская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" Способ коррекции гиперэстрадиолемии и нормогонадотропного гипогонадизма у мужчин
UA113291C2 (xx) 2011-08-04 2017-01-10 Метаболіти транскломіфену і їх застосування
CA2881604C (en) * 2011-08-09 2021-09-14 Kenneth W. Adams Use of aromatase inhibitor or estrogen blocker for increasing spermatogenesis or testosterone levels in males
US10328022B2 (en) 2012-05-31 2019-06-25 Repros Therapeutics Inc. Formulations and methods for vaginal delivery of antiprogestins
CN104582686A (zh) * 2012-08-21 2015-04-29 利普生物药剂公司 反式克罗米酚(trans-clomiphene)调配物和其用途
MX2015005160A (es) 2012-11-02 2015-07-17 Repros Therapeutics Inc Trans-clomifeno para uso en terapia de cancer.
WO2014070517A1 (en) 2012-11-02 2014-05-08 Repros Therapeutics Inc. Methods and compositions for treating progesterone-dependent conditions
US9814687B2 (en) * 2014-08-20 2017-11-14 Professional Compounding Centers Of America Transdermal pharmaceutical compositions including C-SERMs for low testosterone levels in men
RU2586305C1 (ru) * 2015-02-02 2016-06-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ивановская государственная медицинская академия" Министерства здравоохранения Российской Федерации Способ лечения обструктивной азооспермии и криптозооспермии у пациентов с хроническим простатитом
CA2989364C (en) 2016-04-22 2021-07-20 F.I.S. - Fabbrica Italiana Sintetici S.P.A. Process for the preparation of enclomiphene citrate having needle shaped crystal habit.

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Also Published As

Publication number Publication date
CL2004000026A1 (es) 2005-02-04
US20100286281A1 (en) 2010-11-11
CN1289075C (zh) 2006-12-13
MXPA04000097A (es) 2004-05-21
JP4845165B2 (ja) 2011-12-28
CA2777199A1 (en) 2003-01-23
HK1071521A1 (en) 2005-07-22
US20140093560A1 (en) 2014-04-03
KR20040013131A (ko) 2004-02-11
CY1108563T1 (el) 2014-04-09
WO2003005954A3 (en) 2003-10-23
PL374121A1 (en) 2005-10-03
CO5550428A2 (es) 2005-08-31
ECSP044937A (es) 2004-04-28
ZA200400142B (en) 2006-02-22
US8618176B2 (en) 2013-12-31
US7368480B2 (en) 2008-05-06
NZ551013A (en) 2008-04-30
WO2003005954A2 (en) 2003-01-23
RU2004100535A (ru) 2005-06-10
US20160354325A1 (en) 2016-12-08
WO2003005954B1 (en) 2003-12-04
JP2005520779A (ja) 2005-07-14
US20040241224A1 (en) 2004-12-02
EP1411916B1 (en) 2008-08-27
US20150265553A1 (en) 2015-09-24
CA2453337A1 (en) 2003-01-23
RU2297218C2 (ru) 2007-04-20
PL211339B1 (pl) 2012-05-31
CN1551765A (zh) 2004-12-01
US20040097597A1 (en) 2004-05-20
CA2453337C (en) 2012-08-28
NZ530491A (en) 2007-08-31
DK1411916T3 (da) 2008-12-15
CN1954807A (zh) 2007-05-02
DE60228583D1 (de) 2008-10-09
JP2009280623A (ja) 2009-12-03
ATE406153T1 (de) 2008-09-15
US7759360B2 (en) 2010-07-20
PT1411916E (pt) 2008-12-10
KR100851648B1 (ko) 2008-08-13
AU2002318225B2 (en) 2007-12-13
US10561624B2 (en) 2020-02-18
EP1411916A2 (en) 2004-04-28
EP1411916A4 (en) 2005-08-17
ES2312593T3 (es) 2009-03-01

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