EP0802787A4 - In situ gel-forming delivery vehicle for bio-affecting substances, and method of use - Google Patents

In situ gel-forming delivery vehicle for bio-affecting substances, and method of use

Info

Publication number
EP0802787A4
EP0802787A4 EP95921627A EP95921627A EP0802787A4 EP 0802787 A4 EP0802787 A4 EP 0802787A4 EP 95921627 A EP95921627 A EP 95921627A EP 95921627 A EP95921627 A EP 95921627A EP 0802787 A4 EP0802787 A4 EP 0802787A4
Authority
EP
European Patent Office
Prior art keywords
bio
delivery vehicle
situ gel
affecting substances
forming delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95921627A
Other languages
German (de)
French (fr)
Other versions
EP0802787A1 (en
Inventor
Kenneth J Himmelstein
Bert O Haglund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Nebraska
Original Assignee
University of Nebraska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Nebraska filed Critical University of Nebraska
Publication of EP0802787A1 publication Critical patent/EP0802787A1/en
Publication of EP0802787A4 publication Critical patent/EP0802787A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
EP95921627A 1994-06-17 1995-06-09 In situ gel-forming delivery vehicle for bio-affecting substances, and method of use Withdrawn EP0802787A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26173194A 1994-06-17 1994-06-17
US261731 1994-06-17
PCT/US1995/007333 WO1995035093A1 (en) 1994-06-17 1995-06-09 In situ gel-forming delivery vehicle for bio-affecting substances, and method of use

Publications (2)

Publication Number Publication Date
EP0802787A1 EP0802787A1 (en) 1997-10-29
EP0802787A4 true EP0802787A4 (en) 1998-09-02

Family

ID=22994617

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95921627A Withdrawn EP0802787A4 (en) 1994-06-17 1995-06-09 In situ gel-forming delivery vehicle for bio-affecting substances, and method of use

Country Status (5)

Country Link
EP (1) EP0802787A4 (en)
JP (1) JPH10501814A (en)
AU (1) AU2638795A (en)
CA (1) CA2192708A1 (en)
WO (1) WO1995035093A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2737406B1 (en) † 1995-08-04 1997-10-24 Sederma Sa PHYSICAL ACTIVITY GEL FOR COSMETIC PRODUCTS
US20020064546A1 (en) * 1996-09-13 2002-05-30 J. Milton Harris Degradable poly(ethylene glycol) hydrogels with controlled half-life and precursors therefor
US6258351B1 (en) 1996-11-06 2001-07-10 Shearwater Corporation Delivery of poly(ethylene glycol)-modified molecules from degradable hydrogels
DE19701912C1 (en) 1997-01-10 1998-05-14 Jenapharm Gmbh Implant for controlled drug release
US6596291B2 (en) 1997-12-05 2003-07-22 Thomas A. Bell Compositions and methods for treating surfaces infected with ectoparasitic insects
JP4557113B2 (en) * 1998-12-28 2010-10-06 大正製薬株式会社 Topical preparation
WO2000064977A1 (en) * 1999-04-26 2000-11-02 California Institute Of Technology In situ forming hydrogels
US7173064B2 (en) 2001-07-09 2007-02-06 Repros Therapeutics Inc. Methods and compositions with trans-clomiphene for treating wasting and lipodystrophy
KR100851648B1 (en) 2001-07-09 2008-08-13 레프로스 쎄라피우틱스 아이엔씨. Materials for the treatment of testosterone deficiency in men
US7737185B2 (en) 2001-07-09 2010-06-15 Repros Therapeutics Inc. Methods and compositions with trans-clomiphene
SE0302509D0 (en) * 2003-09-19 2003-09-19 Amersham Biosciences Ab Matrix for separation of polyethers and method of separation
KR20070100811A (en) 2005-02-04 2007-10-11 레프로스 쎄라피우틱스 아이엔씨. Methods and materials with trans-clomiphene for the treatment of male infertility
WO2006102232A2 (en) 2005-03-22 2006-09-28 Repros Therapeutics Inc. Dosing regimes for trans-clomiphene
BRPI0818637A2 (en) 2007-10-16 2015-04-07 Repros Therapeutics Inc Methods of treating symptom of impaired fasting glucose, metabolic syndrome, metabolic syndrome, and impaired fasting glucose in subjects with secondary or idiopathic hypogonadotropic hypogonadism
UA113291C2 (en) 2011-08-04 2017-01-10 TRANSCLOMYPHENE METABOLITES AND THEIR APPLICATIONS
US9687458B2 (en) 2012-11-02 2017-06-27 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
WO2016170531A1 (en) * 2015-04-20 2016-10-27 Botanocap Ltd. Liquid and solid core microcapsules formed by interpolymeric complexation
WO2020033677A1 (en) 2018-08-08 2020-02-13 Johnson Lanny Leo Methods of diagnosing and treating infected implants

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9535093A1 *

Also Published As

Publication number Publication date
EP0802787A1 (en) 1997-10-29
WO1995035093A1 (en) 1995-12-28
AU2638795A (en) 1996-01-15
JPH10501814A (en) 1998-02-17
CA2192708A1 (en) 1995-12-28

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