DK1411916T3 - Fremgangsmåder og materialer til behandling af testosteronmangel hos mænd - Google Patents
Fremgangsmåder og materialer til behandling af testosteronmangel hos mændInfo
- Publication number
- DK1411916T3 DK1411916T3 DK02748104T DK02748104T DK1411916T3 DK 1411916 T3 DK1411916 T3 DK 1411916T3 DK 02748104 T DK02748104 T DK 02748104T DK 02748104 T DK02748104 T DK 02748104T DK 1411916 T3 DK1411916 T3 DK 1411916T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- men
- materials
- testosterone deficiency
- treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Beans For Foods Or Fodder (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30431301P | 2001-07-09 | 2001-07-09 | |
PCT/US2002/021524 WO2003005954A2 (en) | 2001-07-09 | 2002-07-09 | Methods and materials for the treatment of testosterone deficiency in men |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1411916T3 true DK1411916T3 (da) | 2008-12-15 |
Family
ID=23175972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02748104T DK1411916T3 (da) | 2001-07-09 | 2002-07-09 | Fremgangsmåder og materialer til behandling af testosteronmangel hos mænd |
Country Status (24)
Country | Link |
---|---|
US (6) | US7759360B2 (es) |
EP (1) | EP1411916B1 (es) |
JP (2) | JP4845165B2 (es) |
KR (1) | KR100851648B1 (es) |
CN (2) | CN1954807A (es) |
AT (1) | ATE406153T1 (es) |
AU (1) | AU2002318225B2 (es) |
BR (1) | BR0211067A (es) |
CA (2) | CA2453337C (es) |
CL (1) | CL2004000026A1 (es) |
CO (1) | CO5550428A2 (es) |
CY (1) | CY1108563T1 (es) |
DE (1) | DE60228583D1 (es) |
DK (1) | DK1411916T3 (es) |
EC (1) | ECSP044937A (es) |
ES (1) | ES2312593T3 (es) |
HK (1) | HK1071521A1 (es) |
MX (1) | MXPA04000097A (es) |
NZ (2) | NZ551013A (es) |
PL (1) | PL211339B1 (es) |
PT (1) | PT1411916E (es) |
RU (1) | RU2297218C2 (es) |
WO (1) | WO2003005954A2 (es) |
ZA (1) | ZA200400142B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7737185B2 (en) * | 2001-07-09 | 2010-06-15 | Repros Therapeutics Inc. | Methods and compositions with trans-clomiphene |
BR0211067A (pt) | 2001-07-09 | 2006-10-31 | Zonagen Inc | métodos e materiais para o tratamento de deficiência de testosterona em homens |
US7173064B2 (en) | 2001-07-09 | 2007-02-06 | Repros Therapeutics Inc. | Methods and compositions with trans-clomiphene for treating wasting and lipodystrophy |
MX2007000050A (es) * | 2004-07-14 | 2007-07-10 | Repros Therapeutics Inc | Trans-clomifeno para el tratamiento de hipertrofia de prostata benigna, cancer de prostata, hipogonadismo, trigliceridos elevados y colesterol elevado. |
CA2595363C (en) * | 2005-02-04 | 2012-03-27 | Repros Therapeutics Inc. | Methods and materials with trans-clomiphene for the treatment of male infertility |
US8247456B2 (en) * | 2005-03-22 | 2012-08-21 | Repros Therapeutics Inc. | Dosing regimes for trans-clomiphene |
US20080312239A1 (en) * | 2007-06-13 | 2008-12-18 | Quatrx Pharmaceuticals Company | Methods for the treatment of erectile dysfunction using fispemifene |
US20110118355A1 (en) * | 2007-09-21 | 2011-05-19 | Harry Fisch | Treatment of migraine headaches using antiestrogens |
MY150082A (en) | 2007-10-16 | 2013-11-29 | Repros Therapeutics Inc | Trans-clomiphene for metabolic syndrome |
WO2009052377A1 (en) * | 2007-10-18 | 2009-04-23 | Harry Fisch | Treatment of migraine headaches using antiestrogens |
US20090215738A1 (en) * | 2008-02-26 | 2009-08-27 | Michael Charles Scally | Prevention and treatment of an increase in cardiovascular risk, adverse cardiovascular events, infertility, and adverse psychological effects after androgen or gnrh analogue intake |
TWI477276B (zh) | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | 抗黃體素給藥方案 |
RU2474424C2 (ru) * | 2010-09-24 | 2013-02-10 | Государственное образовательное учреждение высшего профессионального образования "Ивановская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" | Способ коррекции гиперэстрадиолемии и нормогонадотропного гипогонадизма у мужчин |
UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
WO2013020215A1 (en) * | 2011-08-09 | 2013-02-14 | Adams Kenneth W | Use of aromatase inhibitor or estrogen blocker for increasing spermatogenesis or testosterone levels in males |
NZ702467A (en) | 2012-05-31 | 2016-07-29 | Repros Therapeutics Inc | Formulations and methods for vaginal delivery of antiprogestins |
SG10201704820SA (en) * | 2012-08-21 | 2017-07-28 | Repros Therapeutics Inc | Trans-clomiphene formulations and uses thereof |
AU2013338311A1 (en) | 2012-11-02 | 2015-05-14 | Repros Therapeutics Inc. | Trans-clomiphene for use in cancer therapy |
CA2888377C (en) | 2012-11-02 | 2021-02-02 | Repros Therapeutics Inc. | Methods and compositions for treating progesterone-dependent conditions |
US9814687B2 (en) * | 2014-08-20 | 2017-11-14 | Professional Compounding Centers Of America | Transdermal pharmaceutical compositions including C-SERMs for low testosterone levels in men |
RU2586305C1 (ru) * | 2015-02-02 | 2016-06-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Ивановская государственная медицинская академия" Министерства здравоохранения Российской Федерации | Способ лечения обструктивной азооспермии и криптозооспермии у пациентов с хроническим простатитом |
EP3368506B1 (en) | 2016-04-22 | 2023-09-06 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Process for the preparation of enclomiphene citrate having needle shaped crystal habit. |
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US4061733A (en) * | 1976-10-15 | 1977-12-06 | Narayan Vishwanath Gunjikar | Veterinary compositions for inducing estrus in animals and method |
US4729999A (en) * | 1984-10-12 | 1988-03-08 | Bcm Technologies | Antiestrogen therapy for symptoms of estrogen deficiency |
ATE36312T1 (de) | 1985-06-08 | 1988-08-15 | Asta Pharma Ag | Neue derivate des 1,1,2,2-tetramethyl-1,2-bis-(2fluor-4-hydroxyphenyl)-ethans. |
US4820736A (en) * | 1987-03-20 | 1989-04-11 | Yale University | Use of clomiphene to predict fertility in a human female |
GB8926171D0 (en) | 1989-11-20 | 1990-01-10 | Applied Research Systems | Treatment of infertility |
JPH04312522A (ja) | 1991-04-08 | 1992-11-04 | Yoshiaki Kawashima | 徐放性錠剤の製造方法 |
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DE4435368A1 (de) * | 1994-09-22 | 1996-03-28 | Schering Ag | Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann |
DE69617245T2 (de) * | 1995-08-17 | 2002-07-25 | Csir Pretoria | Produkte mit gesteuerter freisetzung |
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IL120262A (en) * | 1996-02-28 | 2001-01-28 | Pfizer | Droloxifene and derivatives thereof for use in increasing serum testosterone levels |
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US6322797B1 (en) * | 1997-04-03 | 2001-11-27 | Guilford Pharmaceuticals, Inc. | Biodegradable terephthalate polyester-poly (phosphate) polymers, compositions, articles, and methods for making and using the same |
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JP2003534375A (ja) * | 2000-05-26 | 2003-11-18 | フィッチ,ハリー | 選択性抗エストロゲン薬を用いた男性におけるアンドロゲン欠乏症の治療法 |
US7067557B2 (en) * | 2000-05-26 | 2006-06-27 | Harry Fisch | Methods of treating androgen deficiency in men using selective antiestrogens |
JP2004507465A (ja) * | 2000-08-11 | 2004-03-11 | ワイス | エストロゲン受容体陽性癌腫の治療方法 |
US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
US20040192598A1 (en) | 2000-10-11 | 2004-09-30 | Laura Kragie | Composition and method of alleviating adverse side effects and/or enhancing efficacy of agents that inhibit aromatase |
CA2431566A1 (en) * | 2000-12-11 | 2002-07-18 | Testocreme, Llc | Topical testosterone formulations and associated methods |
BR0211067A (pt) | 2001-07-09 | 2006-10-31 | Zonagen Inc | métodos e materiais para o tratamento de deficiência de testosterona em homens |
US7173064B2 (en) * | 2001-07-09 | 2007-02-06 | Repros Therapeutics Inc. | Methods and compositions with trans-clomiphene for treating wasting and lipodystrophy |
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US20060269611A1 (en) * | 2001-11-29 | 2006-11-30 | Steiner Mitchell S | Prevention and treatment of androgen-deprivation induced osteoporosis |
US7105679B2 (en) * | 2001-12-19 | 2006-09-12 | Kanojia Ramesh M | Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators |
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MX2007000050A (es) | 2004-07-14 | 2007-07-10 | Repros Therapeutics Inc | Trans-clomifeno para el tratamiento de hipertrofia de prostata benigna, cancer de prostata, hipogonadismo, trigliceridos elevados y colesterol elevado. |
CA2595363C (en) | 2005-02-04 | 2012-03-27 | Repros Therapeutics Inc. | Methods and materials with trans-clomiphene for the treatment of male infertility |
JP2008537538A (ja) * | 2005-02-11 | 2008-09-18 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Vegf拮抗剤及び降圧剤の治療的組み合わせ |
US8247456B2 (en) | 2005-03-22 | 2012-08-21 | Repros Therapeutics Inc. | Dosing regimes for trans-clomiphene |
CA2617905A1 (en) | 2005-08-05 | 2007-02-15 | Repros Therapeutics Inc. | Methods and compositions for treating female infertility using clomiphene |
EP1829534A1 (en) | 2006-03-02 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Use of compounds binding to the sigma receptor for the treatment of metabolic syndrome |
MY150082A (en) * | 2007-10-16 | 2013-11-29 | Repros Therapeutics Inc | Trans-clomiphene for metabolic syndrome |
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TWI458478B (zh) | 2008-11-07 | 2014-11-01 | Repros Therapeutics Inc | 用於代謝症候群與第2型糖尿病的反式氯米芬 |
US20100144687A1 (en) * | 2008-12-05 | 2010-06-10 | Glaser Rebecca L | Pharmaceutical compositions containing testosterone and an aromatase inhibitor |
WO2013020215A1 (en) | 2011-08-09 | 2013-02-14 | Adams Kenneth W | Use of aromatase inhibitor or estrogen blocker for increasing spermatogenesis or testosterone levels in males |
-
2002
- 2002-07-09 BR BRPI0211067-9A patent/BR0211067A/pt not_active Application Discontinuation
- 2002-07-09 ES ES02748104T patent/ES2312593T3/es not_active Expired - Lifetime
- 2002-07-09 PT PT02748104T patent/PT1411916E/pt unknown
- 2002-07-09 US US10/483,458 patent/US7759360B2/en not_active Expired - Fee Related
- 2002-07-09 AU AU2002318225A patent/AU2002318225B2/en not_active Expired
- 2002-07-09 DK DK02748104T patent/DK1411916T3/da active
- 2002-07-09 KR KR1020047000258A patent/KR100851648B1/ko active IP Right Grant
- 2002-07-09 NZ NZ551013A patent/NZ551013A/en not_active IP Right Cessation
- 2002-07-09 MX MXPA04000097A patent/MXPA04000097A/es active IP Right Grant
- 2002-07-09 PL PL374121A patent/PL211339B1/pl unknown
- 2002-07-09 JP JP2003511763A patent/JP4845165B2/ja not_active Expired - Fee Related
- 2002-07-09 CN CNA2006101356235A patent/CN1954807A/zh active Pending
- 2002-07-09 AT AT02748104T patent/ATE406153T1/de active
- 2002-07-09 DE DE60228583T patent/DE60228583D1/de not_active Expired - Lifetime
- 2002-07-09 EP EP02748104A patent/EP1411916B1/en not_active Expired - Lifetime
- 2002-07-09 CN CNB028174410A patent/CN1289075C/zh not_active Expired - Lifetime
- 2002-07-09 CA CA2453337A patent/CA2453337C/en not_active Expired - Lifetime
- 2002-07-09 WO PCT/US2002/021524 patent/WO2003005954A2/en active Application Filing
- 2002-07-09 CA CA2777199A patent/CA2777199A1/en not_active Abandoned
- 2002-07-09 RU RU2004100535/14A patent/RU2297218C2/ru active
- 2002-07-09 NZ NZ530491A patent/NZ530491A/en not_active IP Right Cessation
-
2003
- 2003-04-30 US US10/427,768 patent/US7368480B2/en not_active Expired - Lifetime
-
2004
- 2004-01-06 EC EC2004004937A patent/ECSP044937A/es unknown
- 2004-01-08 CL CL200400026A patent/CL2004000026A1/es unknown
- 2004-01-08 ZA ZA200400142A patent/ZA200400142B/en unknown
- 2004-01-09 CO CO04001222A patent/CO5550428A2/es not_active Application Discontinuation
-
2005
- 2005-05-25 HK HK05104390A patent/HK1071521A1/xx not_active IP Right Cessation
-
2008
- 2008-11-13 CY CY20081101298T patent/CY1108563T1/el unknown
-
2009
- 2009-09-03 JP JP2009204154A patent/JP2009280623A/ja not_active Withdrawn
-
2010
- 2010-07-16 US US12/838,036 patent/US8618176B2/en not_active Expired - Lifetime
-
2013
- 2013-12-03 US US14/095,494 patent/US20140093560A1/en not_active Abandoned
-
2015
- 2015-06-09 US US14/734,931 patent/US20150265553A1/en not_active Abandoned
-
2016
- 2016-08-17 US US15/239,394 patent/US10561624B2/en not_active Expired - Fee Related
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