JP4806214B2 - 電子捕獲解離反応装置 - Google Patents
電子捕獲解離反応装置 Download PDFInfo
- Publication number
- JP4806214B2 JP4806214B2 JP2005160861A JP2005160861A JP4806214B2 JP 4806214 B2 JP4806214 B2 JP 4806214B2 JP 2005160861 A JP2005160861 A JP 2005160861A JP 2005160861 A JP2005160861 A JP 2005160861A JP 4806214 B2 JP4806214 B2 JP 4806214B2
- Authority
- JP
- Japan
- Prior art keywords
- electron
- electrode
- ecd
- ion
- magnetic field
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/422—Two-dimensional RF ion traps
- H01J49/4225—Multipole linear ion traps, e.g. quadrupoles, hexapoles
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
- H01J49/005—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by collision with gas, e.g. by introducing gas or by accelerating ions with an electric field
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
- H01J49/0054—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by an electron beam, e.g. electron impact dissociation, electron capture dissociation
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005160861A JP4806214B2 (ja) | 2005-01-28 | 2005-06-01 | 電子捕獲解離反応装置 |
| US11/338,844 US7309860B2 (en) | 2005-01-28 | 2006-01-25 | Mass spectrometer |
| US11/979,219 US7589320B2 (en) | 2005-01-28 | 2007-10-31 | Mass spectrometer |
| US12/461,292 US8080786B2 (en) | 2005-01-28 | 2009-08-06 | Mass spectrometer |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005020543 | 2005-01-28 | ||
| JP2005020543 | 2005-01-28 | ||
| JP2005160861A JP4806214B2 (ja) | 2005-01-28 | 2005-06-01 | 電子捕獲解離反応装置 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011145630A Division JP5210418B2 (ja) | 2005-01-28 | 2011-06-30 | 質量分析装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006234782A JP2006234782A (ja) | 2006-09-07 |
| JP2006234782A5 JP2006234782A5 (enExample) | 2008-03-21 |
| JP4806214B2 true JP4806214B2 (ja) | 2011-11-02 |
Family
ID=36755518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005160861A Expired - Fee Related JP4806214B2 (ja) | 2005-01-28 | 2005-06-01 | 電子捕獲解離反応装置 |
Country Status (2)
| Country | Link |
|---|---|
| US (3) | US7309860B2 (enExample) |
| JP (1) | JP4806214B2 (enExample) |
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10950425B2 (en) | 2016-08-16 | 2021-03-16 | Micromass Uk Limited | Mass analyser having extended flight path |
| US11049712B2 (en) | 2017-08-06 | 2021-06-29 | Micromass Uk Limited | Fields for multi-reflecting TOF MS |
| US11081332B2 (en) | 2017-08-06 | 2021-08-03 | Micromass Uk Limited | Ion guide within pulsed converters |
| US11205568B2 (en) | 2017-08-06 | 2021-12-21 | Micromass Uk Limited | Ion injection into multi-pass mass spectrometers |
| US11211238B2 (en) | 2017-08-06 | 2021-12-28 | Micromass Uk Limited | Multi-pass mass spectrometer |
| US11239067B2 (en) | 2017-08-06 | 2022-02-01 | Micromass Uk Limited | Ion mirror for multi-reflecting mass spectrometers |
| US11295944B2 (en) | 2017-08-06 | 2022-04-05 | Micromass Uk Limited | Printed circuit ion mirror with compensation |
| US11309175B2 (en) | 2017-05-05 | 2022-04-19 | Micromass Uk Limited | Multi-reflecting time-of-flight mass spectrometers |
| US11328920B2 (en) | 2017-05-26 | 2022-05-10 | Micromass Uk Limited | Time of flight mass analyser with spatial focussing |
| US11342175B2 (en) | 2018-05-10 | 2022-05-24 | Micromass Uk Limited | Multi-reflecting time of flight mass analyser |
| US11367608B2 (en) | 2018-04-20 | 2022-06-21 | Micromass Uk Limited | Gridless ion mirrors with smooth fields |
| US11587779B2 (en) | 2018-06-28 | 2023-02-21 | Micromass Uk Limited | Multi-pass mass spectrometer with high duty cycle |
| US11621156B2 (en) | 2018-05-10 | 2023-04-04 | Micromass Uk Limited | Multi-reflecting time of flight mass analyser |
| US11817303B2 (en) | 2017-08-06 | 2023-11-14 | Micromass Uk Limited | Accelerator for multi-pass mass spectrometers |
| US11848185B2 (en) | 2019-02-01 | 2023-12-19 | Micromass Uk Limited | Electrode assembly for mass spectrometer |
| US11881387B2 (en) | 2018-05-24 | 2024-01-23 | Micromass Uk Limited | TOF MS detection system with improved dynamic range |
| US12205813B2 (en) | 2019-03-20 | 2025-01-21 | Micromass Uk Limited | Multiplexed time of flight mass spectrometer |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006093901A2 (en) * | 2005-02-28 | 2006-09-08 | Cedars-Sinai Medical Center | Bi-directional system for mass spectrometry |
| GB0506288D0 (en) * | 2005-03-29 | 2005-05-04 | Thermo Finnigan Llc | Improvements relating to mass spectrometry |
| CA2601707C (en) * | 2005-03-29 | 2012-05-15 | Thermo Finnigan Llc | Improvements relating to a mass spectrometer |
| US7417223B2 (en) * | 2005-10-28 | 2008-08-26 | Mds Inc. | Method, system and computer software product for specific identification of reaction pairs associated by specific neutral differences |
| JP5214607B2 (ja) * | 2006-08-25 | 2013-06-19 | サーモ フィニガン リミテッド ライアビリティ カンパニー | 質量分析計での解離型のデータ依存式選択 |
| JP4918846B2 (ja) * | 2006-11-22 | 2012-04-18 | 株式会社日立製作所 | 質量分析装置及び質量分析方法 |
| JP4940977B2 (ja) * | 2007-02-07 | 2012-05-30 | 株式会社島津製作所 | イオン偏向装置及び質量分析装置 |
| CA2672829A1 (en) * | 2007-02-23 | 2008-08-28 | Brigham Young University | Coaxial hybrid radio frequency ion trap mass analyzer |
| JP2009068981A (ja) * | 2007-09-13 | 2009-04-02 | Hitachi High-Technologies Corp | 質量分析システム及び質量分析方法 |
| DE102008003676B4 (de) * | 2008-01-09 | 2011-07-21 | Bruker Daltonik GmbH, 28359 | Ionenmobilitätsspektrometer mit einer nicht radioaktiven Elektronenquelle |
| DE102008023693A1 (de) * | 2008-05-15 | 2009-11-19 | Bruker Daltonik Gmbh | 3D-Ionenfalle als Fragmentierungszelle |
| EP2304767B1 (en) * | 2008-05-30 | 2020-02-26 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | A radio-frequency-free hybrid electrostatic/magnetostatic cell for transporting, trapping, and dissociating ions in mass spectrometers |
| JP5039656B2 (ja) | 2008-07-25 | 2012-10-03 | 株式会社日立ハイテクノロジーズ | 質量分析装置および質量分析方法 |
| WO2010095586A1 (ja) * | 2009-02-19 | 2010-08-26 | 株式会社日立ハイテクノロジーズ | 質量分析システム |
| US8134290B2 (en) | 2009-04-30 | 2012-03-13 | Scientific Instrument Services, Inc. | Emission filaments made from a rhenium alloy and method of manufacturing thereof |
| US20100276063A1 (en) * | 2009-05-02 | 2010-11-04 | Henry Hoang Xuan Bui | Methods of manufacturing quadrupole mass filters |
| JP5362009B2 (ja) * | 2009-07-24 | 2013-12-11 | 株式会社日立製作所 | 質量分析方法 |
| US8158934B2 (en) * | 2009-08-25 | 2012-04-17 | Agilent Technologies, Inc. | Electron capture dissociation apparatus and related methods |
| GB201007210D0 (en) | 2010-04-30 | 2010-06-16 | Verenchikov Anatoly | Time-of-flight mass spectrometer with improved duty cycle |
| JP5583550B2 (ja) * | 2010-10-29 | 2014-09-03 | 株式会社アルバック | Gcib(ガスクラスターイオンビーム)銃、表面分析装置および表面分析方法 |
| KR101286561B1 (ko) * | 2011-10-13 | 2013-07-22 | 한국기초과학지원연구원 | 전자 포획 분해용 렌즈, 이를 포함하는 푸리에 변환 이온 싸이클로트론 공명 질량 분석기 및 푸리에 변환 이온 싸이클로트론 공명 질량 분석기의 신호 개선을 위한 방법 |
| US8575542B1 (en) * | 2012-04-18 | 2013-11-05 | Bruker Daltonics, Inc. | Method and device for gas-phase ion fragmentation |
| ES2436853B1 (es) * | 2012-05-30 | 2014-12-29 | Universidad De Granada | Dispositivo para la producción de haces monocromáticos de electrones y métodos para la calibración de detectores y medida del perfil de haces de electrones |
| EP2883237B1 (en) | 2012-08-16 | 2020-11-25 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Electromagnetostatic electron-induced dissociation cell |
| US8754361B1 (en) * | 2013-03-11 | 2014-06-17 | 1St Detect Corporation | Systems and methods for adjusting a mass spectrometer output |
| CA2912998A1 (en) | 2013-05-30 | 2014-12-04 | Dh Technologies Development Pte. Ltd. | Inline ion reaction device cell and method of operation |
| EP2858090B1 (en) * | 2013-10-02 | 2016-06-22 | Bruker Daltonik GmbH | Introduction of ions into ion cyclotron resonance cells |
| GB201406981D0 (en) * | 2014-04-17 | 2014-06-04 | Micromass Ltd | Hybrid acquisition method incorporating electron transfer dissociation triggered from fast sequential 2D MS/MS collision induced dissociation |
| DE112015001841B4 (de) | 2014-04-17 | 2024-08-22 | Micromass Uk Limited | Hybrid-Erfassungsverfahren unter Einbeziehung mehrerer Dissoziationstechniken |
| WO2017093860A1 (en) * | 2015-11-30 | 2017-06-08 | Dh Technologies Development Pte. Ltd. | Optimized electromagnetic field on side-on ft-icr mass spectrometers |
| JP6958329B2 (ja) | 2017-12-20 | 2021-11-02 | トヨタ自動車株式会社 | ハイブリッド車両 |
| CN109065437B (zh) * | 2018-08-03 | 2020-04-24 | 北京理工大学 | 一种四极电场联合偶极电场的离子共振激发操作方法和装置 |
| WO2020049694A1 (ja) * | 2018-09-06 | 2020-03-12 | 株式会社島津製作所 | 四重極質量分析装置 |
| US20200152437A1 (en) * | 2018-11-14 | 2020-05-14 | Northrop Grumman Systems Corporation | Tapered magnetic ion transport tunnel for particle collection |
| US11791149B2 (en) * | 2019-07-31 | 2023-10-17 | Agilent Technologies, Inc. | Axially progressive lens for transporting charged particles |
| CN114342040B (zh) * | 2019-09-18 | 2024-11-15 | 株式会社岛津制作所 | 离子分析装置 |
| KR102489567B1 (ko) * | 2020-11-30 | 2023-01-18 | 영인에이스 주식회사 | 질량 분석기의 동작 방법 |
| GB202317276D0 (en) * | 2023-11-10 | 2023-12-27 | Micromass Ltd | Device for reacting analyte ions with electrons |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340983A (en) * | 1992-05-18 | 1994-08-23 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Method and apparatus for mass analysis using slow monochromatic electrons |
| JP3305473B2 (ja) * | 1994-01-12 | 2002-07-22 | 横河電機株式会社 | イオントラップ型質量分析計 |
| JP3264775B2 (ja) * | 1994-06-29 | 2002-03-11 | 電気化学工業株式会社 | 熱電界放射電子銃 |
| JP3495512B2 (ja) * | 1996-07-02 | 2004-02-09 | 株式会社日立製作所 | イオントラップ質量分析装置 |
| US6075244A (en) | 1995-07-03 | 2000-06-13 | Hitachi, Ltd. | Mass spectrometer |
| GB9924722D0 (en) * | 1999-10-19 | 1999-12-22 | Shimadzu Res Lab Europe Ltd | Methods and apparatus for driving a quadrupole device |
| DE10058706C1 (de) | 2000-11-25 | 2002-02-28 | Bruker Daltonik Gmbh | Ionenfragmentierung durch Elektroneneinfang in Hochfrequenz-Ionenfallen |
| US6958472B2 (en) | 2001-03-22 | 2005-10-25 | Syddansk Universitet | Mass spectrometry methods using electron capture by ions |
| DE10213652B4 (de) * | 2002-03-27 | 2008-02-21 | Bruker Daltonik Gmbh | Verfahren zur Bestrahlung von Ionen in einer Ionenzyklotronresonanz-Falle mit Elektronen und/oder Photonen |
| EP1586104A2 (en) * | 2003-01-24 | 2005-10-19 | Thermo Finnigan LLC | Controlling ion populations in a mass analyzer |
| EP1602119A4 (en) * | 2003-03-03 | 2010-05-12 | Univ Brigham Young | NOVEL ELECTROIONISATION SOURCE TO ORTHOGONAL ACCELERATION TIME-OF-FLIGHT MASS SPECTROMETRY |
| US6858840B2 (en) | 2003-05-20 | 2005-02-22 | Science & Engineering Services, Inc. | Method of ion fragmentation in a multipole ion guide of a tandem mass spectrometer |
| US7227133B2 (en) | 2003-06-03 | 2007-06-05 | The University Of North Carolina At Chapel Hill | Methods and apparatus for electron or positron capture dissociation |
| DE10325579B4 (de) * | 2003-06-05 | 2007-10-11 | Bruker Daltonik Gmbh | Ionenfragmentierung durch Elektroneneinfang in linearen Ionenfallen |
| US6800851B1 (en) * | 2003-08-20 | 2004-10-05 | Bruker Daltonik Gmbh | Electron-ion fragmentation reactions in multipolar radiofrequency fields |
| JP4275545B2 (ja) * | 2004-02-17 | 2009-06-10 | 株式会社日立ハイテクノロジーズ | 質量分析装置 |
| GB0404106D0 (en) * | 2004-02-24 | 2004-03-31 | Shimadzu Res Lab Europe Ltd | An ion trap and a method for dissociating ions in an ion trap |
| GB2414855A (en) * | 2004-03-30 | 2005-12-07 | Thermo Finnigan Llc | Ion fragmentation by electron capture |
| JP4384542B2 (ja) * | 2004-05-24 | 2009-12-16 | 株式会社日立ハイテクノロジーズ | 質量分析装置 |
-
2005
- 2005-06-01 JP JP2005160861A patent/JP4806214B2/ja not_active Expired - Fee Related
-
2006
- 2006-01-25 US US11/338,844 patent/US7309860B2/en active Active
-
2007
- 2007-10-31 US US11/979,219 patent/US7589320B2/en active Active
-
2009
- 2009-08-06 US US12/461,292 patent/US8080786B2/en not_active Expired - Fee Related
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10950425B2 (en) | 2016-08-16 | 2021-03-16 | Micromass Uk Limited | Mass analyser having extended flight path |
| US11309175B2 (en) | 2017-05-05 | 2022-04-19 | Micromass Uk Limited | Multi-reflecting time-of-flight mass spectrometers |
| US11328920B2 (en) | 2017-05-26 | 2022-05-10 | Micromass Uk Limited | Time of flight mass analyser with spatial focussing |
| US11211238B2 (en) | 2017-08-06 | 2021-12-28 | Micromass Uk Limited | Multi-pass mass spectrometer |
| US11756782B2 (en) | 2017-08-06 | 2023-09-12 | Micromass Uk Limited | Ion mirror for multi-reflecting mass spectrometers |
| US11239067B2 (en) | 2017-08-06 | 2022-02-01 | Micromass Uk Limited | Ion mirror for multi-reflecting mass spectrometers |
| US11295944B2 (en) | 2017-08-06 | 2022-04-05 | Micromass Uk Limited | Printed circuit ion mirror with compensation |
| US11081332B2 (en) | 2017-08-06 | 2021-08-03 | Micromass Uk Limited | Ion guide within pulsed converters |
| US11049712B2 (en) | 2017-08-06 | 2021-06-29 | Micromass Uk Limited | Fields for multi-reflecting TOF MS |
| US11817303B2 (en) | 2017-08-06 | 2023-11-14 | Micromass Uk Limited | Accelerator for multi-pass mass spectrometers |
| US11205568B2 (en) | 2017-08-06 | 2021-12-21 | Micromass Uk Limited | Ion injection into multi-pass mass spectrometers |
| US11367608B2 (en) | 2018-04-20 | 2022-06-21 | Micromass Uk Limited | Gridless ion mirrors with smooth fields |
| US11621156B2 (en) | 2018-05-10 | 2023-04-04 | Micromass Uk Limited | Multi-reflecting time of flight mass analyser |
| US11342175B2 (en) | 2018-05-10 | 2022-05-24 | Micromass Uk Limited | Multi-reflecting time of flight mass analyser |
| US11881387B2 (en) | 2018-05-24 | 2024-01-23 | Micromass Uk Limited | TOF MS detection system with improved dynamic range |
| US11587779B2 (en) | 2018-06-28 | 2023-02-21 | Micromass Uk Limited | Multi-pass mass spectrometer with high duty cycle |
| US11848185B2 (en) | 2019-02-01 | 2023-12-19 | Micromass Uk Limited | Electrode assembly for mass spectrometer |
| US12205813B2 (en) | 2019-03-20 | 2025-01-21 | Micromass Uk Limited | Multiplexed time of flight mass spectrometer |
Also Published As
| Publication number | Publication date |
|---|---|
| US7589320B2 (en) | 2009-09-15 |
| JP2006234782A (ja) | 2006-09-07 |
| US20060169892A1 (en) | 2006-08-03 |
| US7309860B2 (en) | 2007-12-18 |
| US20080078930A1 (en) | 2008-04-03 |
| US20090294646A1 (en) | 2009-12-03 |
| US8080786B2 (en) | 2011-12-20 |
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