JP4790609B2 - 創傷治癒のための方法及び薬剤組成物 - Google Patents

創傷治癒のための方法及び薬剤組成物 Download PDF

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Publication number
JP4790609B2
JP4790609B2 JP2006520104A JP2006520104A JP4790609B2 JP 4790609 B2 JP4790609 B2 JP 4790609B2 JP 2006520104 A JP2006520104 A JP 2006520104A JP 2006520104 A JP2006520104 A JP 2006520104A JP 4790609 B2 JP4790609 B2 JP 4790609B2
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Prior art keywords
wound
insulin
skin
cells
pkc
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JP2006520104A
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Japanese (ja)
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JP2007530426A (ja
Inventor
テンネンバウム、タマル
サンプソン、サンフォード
登志夫 黒木
アルト、アディ
シェン、シュロームシオン
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バーイラン ユニバーシティー
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Priority claimed from US10/644,775 external-priority patent/US20040037828A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006520104A 2003-07-15 2004-07-15 創傷治癒のための方法及び薬剤組成物 Expired - Fee Related JP4790609B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US48690603P 2003-07-15 2003-07-15
US60/486,906 2003-07-15
US10/644,775 US20040037828A1 (en) 2002-07-09 2003-08-21 Methods and pharmaceutical compositions for healing wounds
US10/644,775 2003-08-21
PCT/IL2004/000640 WO2005007072A2 (en) 2003-07-15 2004-07-15 Methods and pharmaceutical compositions for healing wounds

Related Child Applications (3)

Application Number Title Priority Date Filing Date
JP2010285810A Division JP2011057711A (ja) 2003-07-15 2010-12-22 創傷治癒のための方法及び薬剤組成物
JP2010285808A Division JP2011057709A (ja) 2003-07-15 2010-12-22 創傷治癒のための方法及び薬剤組成物
JP2010285809A Division JP2011057710A (ja) 2003-07-15 2010-12-22 創傷治癒のための方法及び薬剤組成物

Publications (2)

Publication Number Publication Date
JP2007530426A JP2007530426A (ja) 2007-11-01
JP4790609B2 true JP4790609B2 (ja) 2011-10-12

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2006520104A Expired - Fee Related JP4790609B2 (ja) 2003-07-15 2004-07-15 創傷治癒のための方法及び薬剤組成物
JP2010285809A Pending JP2011057710A (ja) 2003-07-15 2010-12-22 創傷治癒のための方法及び薬剤組成物
JP2010285810A Pending JP2011057711A (ja) 2003-07-15 2010-12-22 創傷治癒のための方法及び薬剤組成物
JP2010285808A Ceased JP2011057709A (ja) 2003-07-15 2010-12-22 創傷治癒のための方法及び薬剤組成物

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2010285809A Pending JP2011057710A (ja) 2003-07-15 2010-12-22 創傷治癒のための方法及び薬剤組成物
JP2010285810A Pending JP2011057711A (ja) 2003-07-15 2010-12-22 創傷治癒のための方法及び薬剤組成物
JP2010285808A Ceased JP2011057709A (ja) 2003-07-15 2010-12-22 創傷治癒のための方法及び薬剤組成物

Country Status (6)

Country Link
JP (4) JP4790609B2 (enExample)
CN (2) CN1852722B (enExample)
IL (1) IL173148A (enExample)
NZ (3) NZ545318A (enExample)
RU (2) RU2491952C2 (enExample)
ZA (1) ZA200600235B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040037828A1 (en) * 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
WO2005013885A2 (en) * 2003-08-07 2005-02-17 Healor Ltd. Pharmaceutical compositions and methods for accelerating wound healing
EP2653166A3 (en) * 2007-07-30 2014-08-27 Healor Ltd. Pharmaceutical composition and related methods
WO2012063237A2 (en) * 2010-11-08 2012-05-18 Healor Ltd. Buffered ophthalmic compositions and methods of use thereof
US9283175B2 (en) * 2011-07-28 2016-03-15 Ian S. Zagon Methods and compositions for treatment of epithelial wounds
CN103055304A (zh) * 2013-01-19 2013-04-24 卓阳 一种治疗皮肤溃疡用复方温敏凝胶剂及其制备方法
KR101523503B1 (ko) * 2013-09-17 2015-05-29 강원대학교산학협력단 아디포넥틴으로부터 유래한 펩타이드 및 이를 포함하는 조성물
CN106267163A (zh) * 2015-06-09 2017-01-04 济南博创医药科技有限公司 一种治疗皮肤创伤的药物组合物及其药物制剂
CN108514569A (zh) * 2018-07-09 2018-09-11 广州中医药大学(广州中医药研究院) 斜叶檀香提取物在制备皮肤创伤愈合药物中的应用
CN112316148A (zh) * 2019-08-01 2021-02-05 成都夸常奥普医疗科技有限公司 包含血浆的半流体的应用、包含该半流体和活性成分的药物组合物及其制备方法
CN119801477A (zh) * 2023-10-10 2025-04-11 中国石油化工股份有限公司 一种模拟地层弹性形变的实验装置及其使用方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002009639A2 (en) * 2000-07-31 2002-02-07 Bar Ilan University Methods and pharmaceutical compositions for healing wounds
GB2369572A (en) * 2000-11-29 2002-06-05 Raft Trustees Ltd Wound treatment composition comprising insulin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA892928B (en) * 1988-04-25 1991-01-30 Pro Neuron Inc Pharmaceutical compositions containing deoxyribonucleosides for wound healing
US5591709A (en) * 1991-08-30 1997-01-07 Life Medical Sciences, Inc. Compositions and methods for treating wounds
US5948898A (en) * 1992-03-16 1999-09-07 Isis Pharmaceuticals, Inc. Methoxyethoxy oligonucleotides for modulation of protein kinase C expression
US6537973B1 (en) * 1992-03-16 2003-03-25 Isis Pharmaceuticals, Inc. Oligonucleotide inhibition of protein kinase C
GB9210574D0 (en) * 1992-05-18 1992-07-01 Ca Nat Research Council Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications
GB2304047A (en) * 1995-08-09 1997-03-12 Univ Manchester Pharmaceutical compositions containing cytokines
EP1295952A3 (en) * 1996-01-23 2003-07-09 The Board of Trustees of The Leland Stanford Junior University Methods for screening for transdominant effector peptides and RNA molecules
JP2002541195A (ja) * 1999-04-14 2002-12-03 アメリカ合衆国 移植片に対する免疫寛容を誘導するための、免疫毒素および樹状細胞の成熟を阻害する作用剤を含有する組成物
US20020119914A1 (en) * 2000-12-26 2002-08-29 Deguang Zhu New uses of insulin and pancreatin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002009639A2 (en) * 2000-07-31 2002-02-07 Bar Ilan University Methods and pharmaceutical compositions for healing wounds
GB2369572A (en) * 2000-11-29 2002-06-05 Raft Trustees Ltd Wound treatment composition comprising insulin

Also Published As

Publication number Publication date
IL173148A (en) 2013-02-28
JP2007530426A (ja) 2007-11-01
RU2008138473A (ru) 2010-04-10
JP2011057711A (ja) 2011-03-24
CN101850108A (zh) 2010-10-06
NZ588743A (en) 2012-05-25
ZA200600235B (en) 2007-04-25
RU2491952C2 (ru) 2013-09-10
JP2011057709A (ja) 2011-03-24
RU2404799C2 (ru) 2010-11-27
IL173148A0 (en) 2006-06-11
JP2011057710A (ja) 2011-03-24
RU2010130763A (ru) 2012-01-27
CN1852722A (zh) 2006-10-25
NZ545318A (en) 2009-06-26
NZ573737A (en) 2011-06-30
CN1852722B (zh) 2011-06-08

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