JP4775807B2 - 局所麻酔薬物含有ゼリー剤 - Google Patents
局所麻酔薬物含有ゼリー剤 Download PDFInfo
- Publication number
- JP4775807B2 JP4775807B2 JP2004349225A JP2004349225A JP4775807B2 JP 4775807 B2 JP4775807 B2 JP 4775807B2 JP 2004349225 A JP2004349225 A JP 2004349225A JP 2004349225 A JP2004349225 A JP 2004349225A JP 4775807 B2 JP4775807 B2 JP 4775807B2
- Authority
- JP
- Japan
- Prior art keywords
- local anesthetic
- anesthetic drug
- jelly
- acid
- oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 235000015110 jellies Nutrition 0.000 title description 34
- 239000008274 jelly Substances 0.000 title description 33
- 239000003795 chemical substances by application Substances 0.000 claims description 29
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 26
- 235000019658 bitter taste Nutrition 0.000 claims description 17
- 239000000203 mixture Substances 0.000 claims description 17
- 238000002360 preparation method Methods 0.000 claims description 16
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 13
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims description 10
- 229960004194 lidocaine Drugs 0.000 claims description 10
- 229960004393 lidocaine hydrochloride Drugs 0.000 claims description 4
- YECIFGHRMFEPJK-UHFFFAOYSA-N lidocaine hydrochloride monohydrate Chemical compound O.[Cl-].CC[NH+](CC)CC(=O)NC1=C(C)C=CC=C1C YECIFGHRMFEPJK-UHFFFAOYSA-N 0.000 claims description 4
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| JP5434023B2 (ja) * | 2007-09-14 | 2014-03-05 | サンスター株式会社 | 口腔用組成物 |
| JP5336527B2 (ja) * | 2011-01-14 | 2013-11-06 | 株式会社 メドレックス | リドカイン含有ゼリー剤 |
| JP6678946B2 (ja) | 2015-03-25 | 2020-04-15 | テルモ株式会社 | ゲル状局所麻酔剤およびそれを用いたゲル状局所麻酔製剤 |
| WO2018207188A1 (en) * | 2017-05-11 | 2018-11-15 | Steadymed, Ltd. | Enhanced solubility drug-containing formulations |
| CN118265526A (zh) | 2021-11-30 | 2024-06-28 | 玛路弘株式会社 | 药物组合物 |
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| JPS62152465A (ja) * | 1985-12-27 | 1987-07-07 | 三菱レイヨン株式会社 | ゲル状組成物 |
| GB9910212D0 (en) * | 1999-05-05 | 1999-06-30 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| JP5241978B2 (ja) * | 1999-10-13 | 2013-07-17 | 帝國製薬株式会社 | 漢方ゼリー医薬組成物 |
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