JP4773336B2 - Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法 - Google Patents

Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法 Download PDF

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Publication number
JP4773336B2
JP4773336B2 JP2006503710A JP2006503710A JP4773336B2 JP 4773336 B2 JP4773336 B2 JP 4773336B2 JP 2006503710 A JP2006503710 A JP 2006503710A JP 2006503710 A JP2006503710 A JP 2006503710A JP 4773336 B2 JP4773336 B2 JP 4773336B2
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exemplary embodiments
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JP2006503710A
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Japanese (ja)
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JP2006518394A (ja
Inventor
ルリン ファン，
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Eisai R&D Management Co Ltd
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Eisai R&D Management Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006503710A 2003-02-20 2004-02-18 Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法 Expired - Fee Related JP4773336B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44883903P 2003-02-20 2003-02-20
US60/448,839 2003-02-20
PCT/US2004/004921 WO2004074303A2 (en) 2003-02-20 2004-02-18 Reagents and methods for preparing lps antagonist b1287 and stereoisomers thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010230114A Division JP2011037885A (ja) 2003-02-20 2010-10-12 Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法

Publications (2)

Publication Number Publication Date
JP2006518394A JP2006518394A (ja) 2006-08-10
JP4773336B2 true JP4773336B2 (ja) 2011-09-14

Family

ID=32908659

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2006503710A Expired - Fee Related JP4773336B2 (ja) 2003-02-20 2004-02-18 Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法
JP2010230114A Pending JP2011037885A (ja) 2003-02-20 2010-10-12 Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法
JP2013046284A Withdrawn JP2013136625A (ja) 2003-02-20 2013-03-08 Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2010230114A Pending JP2011037885A (ja) 2003-02-20 2010-10-12 Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法
JP2013046284A Withdrawn JP2013136625A (ja) 2003-02-20 2013-03-08 Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法

Country Status (3)

Country Link
US (2) US7906633B2 (enExample)
JP (3) JP4773336B2 (enExample)
WO (1) WO2004074303A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030130212A1 (en) * 1999-01-14 2003-07-10 Rossignol Daniel P. Administration of an anti-endotoxin drug by intravenous infusion
EP2338497A1 (en) * 2001-08-10 2011-06-29 Eisai R&D Management Co., Ltd. Treatment and prevention of heat shock protein-associated diseases and conditions
WO2007026675A1 (ja) * 2005-08-31 2007-03-08 Eisai R & D Management Co., Ltd. リピッドａ類縁体の製造方法
JP5118968B2 (ja) * 2005-08-31 2013-01-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 リピッドａ類縁体の製造方法
ES2392890T3 (es) * 2006-11-22 2012-12-14 Eisai R&D Management Co., Ltd. Sal sódica de un compuesto disacarídico, procedimiento para la producción de la misma y uso de la misma
CA2669674C (en) * 2006-11-22 2016-05-17 Eisai R&D Management Co., Ltd. Sodium salt of disaccharide compound, method for producing the same, and use of the same
US7692311B2 (en) * 2007-11-21 2010-04-06 Powertech Technology Inc. POP (package-on-package) device encapsulating soldered joints between external leads
WO2016057931A1 (en) 2014-10-10 2016-04-14 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration
GB202011823D0 (en) * 2020-07-30 2020-09-16 Givaudan Sa Method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05194470A (ja) * 1991-10-11 1993-08-03 Eisai Co Ltd 抗−エンドトキシン化合物
WO1997011708A1 (en) * 1995-09-29 1997-04-03 Eisai Research Institute Method for treating alcoholic liver disease
WO2001037843A1 (en) * 1999-11-23 2001-05-31 Eisai Co., Ltd. Prevention and treatment of pulmonary bacterial infection or symptomatic pulmonary exposure to endotoxin by inhalation of antiendotoxin drugs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066794A (en) * 1984-08-24 1991-11-19 Daiichi Pharmaceutical Co., Ltd. Process for preparing a disaccharide derivative
US5750664A (en) * 1995-06-05 1998-05-12 Eisai Co., Ltd. Substituted liposaccharides useful in the treatment and prevention of endotoxemia
US6809195B1 (en) * 2000-08-16 2004-10-26 Isis Pharmaceuticals, Inc. Process for the preparation of oligonucleotides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05194470A (ja) * 1991-10-11 1993-08-03 Eisai Co Ltd 抗−エンドトキシン化合物
WO1997011708A1 (en) * 1995-09-29 1997-04-03 Eisai Research Institute Method for treating alcoholic liver disease
WO2001037843A1 (en) * 1999-11-23 2001-05-31 Eisai Co., Ltd. Prevention and treatment of pulmonary bacterial infection or symptomatic pulmonary exposure to endotoxin by inhalation of antiendotoxin drugs

Also Published As

Publication number Publication date
WO2004074303A3 (en) 2004-12-29
US8399634B2 (en) 2013-03-19
JP2006518394A (ja) 2006-08-10
US7906633B2 (en) 2011-03-15
JP2013136625A (ja) 2013-07-11
US20110152508A1 (en) 2011-06-23
WO2004074303A2 (en) 2004-09-02
US20060160999A1 (en) 2006-07-20
JP2011037885A (ja) 2011-02-24

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