JP4745610B2 - 上皮及び網膜組織疾患の治療のための組成物及び治療方法 - Google Patents

上皮及び網膜組織疾患の治療のための組成物及び治療方法 Download PDF

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JP4745610B2
JP4745610B2 JP2003570814A JP2003570814A JP4745610B2 JP 4745610 B2 JP4745610 B2 JP 4745610B2 JP 2003570814 A JP2003570814 A JP 2003570814A JP 2003570814 A JP2003570814 A JP 2003570814A JP 4745610 B2 JP4745610 B2 JP 4745610B2
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substituted
udp
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methylenebenzyl
propyl
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JP2005526046A5 (OSRAM
JP2005526046A (ja
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アール． イエルサ，ベンジャミン
ジー．ザ サード ダグラス，ジェームズ
レイ シェーバー，サミー
エム． ピーターソン，ワード
ジー． ブラウン，エドワード
エス． クリーン，クリストファー
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インスパイアー ファーマシューティカルズ，インコーポレイティド
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
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    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
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    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP2003570814A 2002-02-27 2003-02-27 上皮及び網膜組織疾患の治療のための組成物及び治療方法 Expired - Fee Related JP4745610B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/082,998 2002-02-27
US10/082,998 US7115585B2 (en) 2000-08-21 2002-02-27 Compositions for treating epithelial and retinal tissue diseases
PCT/US2003/006691 WO2003072067A2 (en) 2002-02-27 2003-02-27 Compositions and methods for treating epithelial and retinal tissue diseases

Publications (3)

Publication Number Publication Date
JP2005526046A JP2005526046A (ja) 2005-09-02
JP2005526046A5 JP2005526046A5 (OSRAM) 2006-04-06
JP4745610B2 true JP4745610B2 (ja) 2011-08-10

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JP2003570814A Expired - Fee Related JP4745610B2 (ja) 2002-02-27 2003-02-27 上皮及び網膜組織疾患の治療のための組成物及び治療方法

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US (1) US7115585B2 (OSRAM)
EP (2) EP1545555A4 (OSRAM)
JP (1) JP4745610B2 (OSRAM)
KR (1) KR100990346B1 (OSRAM)
CN (1) CN1671398A (OSRAM)
AR (1) AR038612A1 (OSRAM)
AU (1) AU2003223225B2 (OSRAM)
BR (1) BR0307783A (OSRAM)
CA (1) CA2477241C (OSRAM)
MX (1) MXPA04008293A (OSRAM)
TW (1) TW200408399A (OSRAM)
WO (1) WO2003072067A2 (OSRAM)

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WO2003072067A2 (en) 2003-09-04
EP1545555A4 (en) 2010-09-29
KR20040094736A (ko) 2004-11-10
KR100990346B1 (ko) 2010-10-29
EP2647382A1 (en) 2013-10-09
TW200408399A (en) 2004-06-01
US7115585B2 (en) 2006-10-03
EP1545555A2 (en) 2005-06-29
WO2003072067A3 (en) 2005-04-28
US20030008834A1 (en) 2003-01-09
MXPA04008293A (es) 2004-11-26
AR038612A1 (es) 2005-01-19
JP2005526046A (ja) 2005-09-02
CN1671398A (zh) 2005-09-21
CA2477241C (en) 2012-04-10
CA2477241A1 (en) 2003-09-04
AU2003223225B2 (en) 2007-02-22
AU2003223225A1 (en) 2003-09-09
BR0307783A (pt) 2005-09-13

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