JP4733043B2 - 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法 - Google Patents

改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法 Download PDF

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JP4733043B2
JP4733043B2 JP2006534148A JP2006534148A JP4733043B2 JP 4733043 B2 JP4733043 B2 JP 4733043B2 JP 2006534148 A JP2006534148 A JP 2006534148A JP 2006534148 A JP2006534148 A JP 2006534148A JP 4733043 B2 JP4733043 B2 JP 4733043B2
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dha
potassium
concentration
sodium
ions
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JP2007527233A (ja
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ポール ダブリュー． ベーレンズ
ジョーン エム． トンプソン
カーク アプト
ジョセフ ダブリュー． サード プフェイファー
ジェームス ピー． ウィン
ジェームス ケイシー リップメイヤー
ジョード フィッチタリ
ジョン ハンセン
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マーテック バイオサイエンシーズ コーポレーション
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium

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  • Health & Medical Sciences (AREA)
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  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biomedical Technology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2006534148A 2003-10-02 2004-10-01 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法 Expired - Fee Related JP4733043B2 (ja)

Applications Claiming Priority (3)

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US50850503P 2003-10-02 2003-10-02
US60/508,505 2003-10-02
PCT/US2004/032383 WO2005035775A1 (en) 2003-10-02 2004-10-01 Production of high levels of dha in microalgae using modified amounts of chloride and potassium

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JP2010211893A Division JP5466120B2 (ja) 2003-10-02 2010-09-22 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法

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JP2007527233A JP2007527233A (ja) 2007-09-27
JP4733043B2 true JP4733043B2 (ja) 2011-07-27

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JP2006534148A Expired - Fee Related JP4733043B2 (ja) 2003-10-02 2004-10-01 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法
JP2010211893A Expired - Fee Related JP5466120B2 (ja) 2003-10-02 2010-09-22 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法
JP2013152696A Expired - Fee Related JP5813061B2 (ja) 2003-10-02 2013-07-23 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法
JP2015086549A Expired - Fee Related JP5940194B2 (ja) 2003-10-02 2015-04-21 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法

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JP2013152696A Expired - Fee Related JP5813061B2 (ja) 2003-10-02 2013-07-23 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法
JP2015086549A Expired - Fee Related JP5940194B2 (ja) 2003-10-02 2015-04-21 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法

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US (17) US7163811B2 (enExample)
EP (2) EP1702073B1 (enExample)
JP (4) JP4733043B2 (enExample)
KR (6) KR101295390B1 (enExample)
CN (3) CN103834699A (enExample)
AU (2) AU2004280575B8 (enExample)
CA (2) CA2801065C (enExample)
DK (1) DK1702073T3 (enExample)
ES (1) ES2454196T3 (enExample)
HK (1) HK1199289A1 (enExample)
MX (4) MX271416B (enExample)
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WO (1) WO2005035775A1 (enExample)

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CN1890376A (zh) 2007-01-03
JP2007527233A (ja) 2007-09-27
EP1702073A1 (en) 2006-09-20
US8008050B2 (en) 2011-08-30
EP1702073A4 (en) 2011-08-24
KR101761164B1 (ko) 2017-07-25
US20130158280A1 (en) 2013-06-20
NO20061916L (no) 2006-06-12
CN103834699A (zh) 2014-06-04
AU2004280575B2 (en) 2010-04-22
ES2454196T3 (es) 2014-04-09
CA2540617A1 (en) 2005-04-21
KR20060097009A (ko) 2006-09-13
US20080032353A1 (en) 2008-02-07
AU2010202691B2 (en) 2013-09-12
US20050112736A1 (en) 2005-05-26
CN1890376B (zh) 2012-06-13
US20080032352A1 (en) 2008-02-07
US7745183B2 (en) 2010-06-29
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JP5940194B2 (ja) 2016-06-29
US7163811B2 (en) 2007-01-16
US7871809B2 (en) 2011-01-18
KR20150125731A (ko) 2015-11-09
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US20080032359A1 (en) 2008-02-07
US20140142331A1 (en) 2014-05-22
CA2801065C (en) 2020-04-28
HK1089482A1 (en) 2006-12-01
US20060100279A1 (en) 2006-05-11
US7824892B2 (en) 2010-11-02
US20080032357A1 (en) 2008-02-07
US20080032354A1 (en) 2008-02-07
CA2801065A1 (en) 2005-04-21
US20160108443A1 (en) 2016-04-21
EP1702073B1 (en) 2014-01-01
MX338455B (es) 2016-04-18
AU2004280575B8 (en) 2010-05-13
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DK1702073T3 (da) 2014-04-07
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US20080032358A1 (en) 2008-02-07
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US20080032355A1 (en) 2008-02-07
US9249434B2 (en) 2016-02-02
WO2005035775A1 (en) 2005-04-21
US9834799B2 (en) 2017-12-05
KR20110033283A (ko) 2011-03-30
US7829129B2 (en) 2010-11-09
CN101386873B (zh) 2014-05-07
EP2759599A3 (en) 2014-12-10
MXPA06003467A (es) 2006-06-20
KR101295390B1 (ko) 2013-09-17
US20130150604A1 (en) 2013-06-13
JP2011036261A (ja) 2011-02-24
MX271416B (es) 2009-10-30
KR20140006109A (ko) 2014-01-15
US7252979B2 (en) 2007-08-07
JP2015130886A (ja) 2015-07-23
JP5466120B2 (ja) 2014-04-09
CN101386873A (zh) 2009-03-18
KR20130041366A (ko) 2013-04-24
JP2013212126A (ja) 2013-10-17
US20080044865A1 (en) 2008-02-21
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US20120071677A1 (en) 2012-03-22

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