DK1702073T3 - Produktion af høje niveauer af dha i mikroalger ved anvendelse af modificerede mængder af chlorid og kalium - Google Patents

Produktion af høje niveauer af dha i mikroalger ved anvendelse af modificerede mængder af chlorid og kalium

Info

Publication number
DK1702073T3
DK1702073T3 DK04785345.2T DK04785345T DK1702073T3 DK 1702073 T3 DK1702073 T3 DK 1702073T3 DK 04785345 T DK04785345 T DK 04785345T DK 1702073 T3 DK1702073 T3 DK 1702073T3
Authority
DK
Denmark
Prior art keywords
microalges
dha
potassium
chloride
production
Prior art date
Application number
DK04785345.2T
Other languages
Danish (da)
English (en)
Inventor
Paul W Behrens
John M Thompson
Kirk Apt
Joseph W Pfeifer Iii
James P Wynn
James Casey Lippmeier
Jaouad Fichtali
Jon Hansen
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Application granted granted Critical
Publication of DK1702073T3 publication Critical patent/DK1702073T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK04785345.2T 2003-10-02 2004-10-01 Produktion af høje niveauer af dha i mikroalger ved anvendelse af modificerede mængder af chlorid og kalium DK1702073T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50850503P 2003-10-02 2003-10-02
PCT/US2004/032383 WO2005035775A1 (en) 2003-10-02 2004-10-01 Production of high levels of dha in microalgae using modified amounts of chloride and potassium

Publications (1)

Publication Number Publication Date
DK1702073T3 true DK1702073T3 (da) 2014-04-07

Family

ID=34434916

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04785345.2T DK1702073T3 (da) 2003-10-02 2004-10-01 Produktion af høje niveauer af dha i mikroalger ved anvendelse af modificerede mængder af chlorid og kalium

Country Status (13)

Country Link
US (17) US7163811B2 (enExample)
EP (2) EP1702073B1 (enExample)
JP (4) JP4733043B2 (enExample)
KR (6) KR20130041366A (enExample)
CN (3) CN101386873B (enExample)
AU (2) AU2004280575B8 (enExample)
CA (2) CA2540617A1 (enExample)
DK (1) DK1702073T3 (enExample)
ES (1) ES2454196T3 (enExample)
HK (1) HK1199289A1 (enExample)
MX (4) MX351381B (enExample)
NO (1) NO20061916L (enExample)
WO (1) WO2005035775A1 (enExample)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100051131A (ko) 2000-01-19 2010-05-14 마텍 바이오싸이언스스 코포레이션 무용매 추출 방법
ES2454196T3 (es) * 2003-10-02 2014-04-09 Dsm Ip Assets B.V. Producción de niveles altos de DHA en microalgas utilizando cantidades modificadas de cloruro y potasio
WO2007120801A2 (en) * 2006-04-13 2007-10-25 Nereus Pharmaceuticals, Inc. Fermentation method
EP1847543A1 (de) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
WO2008049512A1 (en) * 2006-10-27 2008-05-02 Lonza Ag Production of omega-3 fatty acids in microflora of thraustochytriales using modified media
CN104069112A (zh) * 2007-10-19 2014-10-01 贝林格尔.英格海姆国际有限公司 取代的哌啶子基-二氢噻吩并嘧啶
JP5563466B2 (ja) 2007-10-19 2014-07-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規ピペラジノ−ジヒドロチエノピリミジン誘導体
KR20100075930A (ko) 2007-10-19 2010-07-05 베링거 인겔하임 인터내셔날 게엠베하 헤테로사이클-치환된 피페라지노-디하이드로티에노피리미딘
AU2009303354C9 (en) 2008-10-14 2017-09-07 Corbion Biotech, Inc. Food compositions of microalgal biomass
US8809037B2 (en) 2008-10-24 2014-08-19 Bioprocessh20 Llc Systems, apparatuses and methods for treating wastewater
EP2194138A1 (en) * 2008-12-08 2010-06-09 Marenutrica GmbH Compositions containing docosahexaenoic acid and method for its production
CN108034680A (zh) 2009-02-25 2018-05-15 V.B.医疗私人有限公司 发酵生产二十二碳六烯酸的改进方法
US8207363B2 (en) * 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
CN102946738B (zh) 2009-04-14 2015-04-01 索拉兹米公司 新颖的微藻食物组合物
BR122015020119B8 (pt) 2010-01-19 2021-05-04 Dsm Ip Assets Bv óleo microbiano, produtos alimentícios para um animal não humano e biomassa isolada
WO2011130578A2 (en) 2010-04-14 2011-10-20 Solazyme, Inc. Lipid-rich microalgal flour food compositions
US20120156669A1 (en) 2010-05-20 2012-06-21 Pond Biofuels Inc. Biomass Production
US8889400B2 (en) 2010-05-20 2014-11-18 Pond Biofuels Inc. Diluting exhaust gas being supplied to bioreactor
US8969067B2 (en) 2010-05-20 2015-03-03 Pond Biofuels Inc. Process for growing biomass by modulating supply of gas to reaction zone
US11512278B2 (en) 2010-05-20 2022-11-29 Pond Technologies Inc. Biomass production
US8940520B2 (en) 2010-05-20 2015-01-27 Pond Biofuels Inc. Process for growing biomass by modulating inputs to reaction zone based on changes to exhaust supply
AU2011261455B2 (en) 2010-06-01 2016-03-24 Dsm Ip Assets B.V. Extraction of lipid from cells and products therefrom
US9023625B2 (en) 2010-06-14 2015-05-05 Io-Mega Holding Corporation Methods for production of algae derived oils
US20120276633A1 (en) 2011-04-27 2012-11-01 Pond Biofuels Inc. Supplying treated exhaust gases for effecting growth of phototrophic biomass
US8795589B1 (en) 2011-04-29 2014-08-05 Cortec Corporation Bio-based volatile corrosion inhibitors
EP2952183A1 (en) 2011-07-21 2015-12-09 DSM IP Assets B.V. Fatty acid compositions
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
CN103773687B (zh) * 2012-10-23 2019-07-12 中国石油化工股份有限公司 一种微藻的培养方法
US9534261B2 (en) 2012-10-24 2017-01-03 Pond Biofuels Inc. Recovering off-gas from photobioreactor
JP2014223024A (ja) * 2013-05-15 2014-12-04 日本電信電話株式会社 微細藻類の培養方法および培養装置
CN103627640B (zh) * 2013-08-10 2018-03-02 青岛海智源生命科技有限公司 一种培养裂殖壶菌的低氯培养基及用该培养基产生dha的方法
CN103468575B (zh) * 2013-09-18 2015-05-06 武汉轻工大学 一株高产dha的寇氏隐甲藻突变株及发酵方法和应用
KR101494649B1 (ko) * 2013-12-03 2015-02-23 한국에너지기술연구원 미생물로부터 차아염소산을 이용한 바이오오일 추출 방법
EP3082794B1 (en) 2013-12-20 2024-05-08 DSM IP Assets B.V. Processes for obtaining microbial oil from microbial cells
CN106029624B (zh) 2013-12-20 2021-12-07 帝斯曼知识产权资产管理有限公司 用于从微生物细胞获得微生物油的方法
CA2934490C (en) 2013-12-20 2022-05-03 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
MX388703B (es) 2013-12-20 2025-03-20 Dsm Ip Assets Bv Procedimientos para obtener aceite microbiano a partir de células microbianas.
AU2014369042B2 (en) 2013-12-20 2020-04-30 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
FR3019559B1 (fr) * 2014-04-03 2018-01-05 Fermentalg Procede de culture des microalgues du genre aurantiochytrium dans un milieu de culture a teneur reduite en sodium et en chlorure pour la production de dha
EP3146060B1 (en) 2014-05-22 2019-12-18 Mara Renewables Corporation Methods of oil production in microorganisms
US20150352034A1 (en) 2014-06-08 2015-12-10 Solazyme, Inc. Personal Care Products Containing Microalgae or Extracts Thereof
FR3025215A1 (fr) * 2014-08-27 2016-03-04 Fermentalg Nouveau procede de culture de microalgues
WO2016100681A1 (en) 2014-12-17 2016-06-23 Solazyme, Inc. Microalgal derived cleaners and surfactants
US9181523B1 (en) 2014-12-29 2015-11-10 Heliae Development Llc Method of treating bacterial contamination in a microalgae culture with pH shock
CN107667164A (zh) 2015-03-24 2018-02-06 泰拉瑞亚控股公司 微藻组合物及其用途
PT3445167T (pt) * 2016-04-18 2021-04-07 Planktonic As Criopreservação de fases juvenis de perceves
JP6998935B2 (ja) 2016-07-13 2022-01-18 エボニック オペレーションズ ゲーエムベーハー 溶解された脂質含有バイオマスから脂質を分離する方法
JP2019530577A (ja) 2016-08-19 2019-10-24 ノーブルジェン・インコーポレーテッド 金属イオンを結合させるための方法及び溶解有機物画分の使用
EP3562925B1 (en) 2016-12-27 2021-03-10 Evonik Operations GmbH Method of isolating lipids from a lipids containing biomass
CA3059271A1 (en) 2017-04-07 2018-10-11 Noblegen Inc. Methods and uses of encapsulated exudates and dried euglena biomass for binding metal
EP3470502A1 (en) 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
CA3101855C (en) 2018-05-15 2023-06-20 Evonik Operations Gmbh Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
BR112020023222A2 (pt) 2018-05-15 2021-03-23 Evonik Operations Gmbh método de isolamento de lipídios a partir de uma biomassa contendo lipídios lisados por inversão por emulsão
KR102455795B1 (ko) * 2020-01-17 2022-10-17 고려대학교 산학협력단 지질 및 오메가-3 함량 증진을 위한 미세조류 배양 방법
EP4469588A1 (en) * 2022-01-25 2024-12-04 DSM IP Assets B.V. Media refinement and nutrient feeding approaches to increase polyunsaturated fatty acid production

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130242A (en) 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US5407957A (en) 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US6410281B1 (en) * 1992-07-10 2002-06-25 Omegatech, Inc. Reducing corrosion in a fermentor by providing sodium with a non-chloride sodium salt
JPH0775556A (ja) * 1993-09-09 1995-03-20 Nisshin Oil Mills Ltd:The ドコサヘキサエン酸含有藻類の培養法
JP3506740B2 (ja) * 1993-09-09 2004-03-15 日清オイリオ株式会社 ドコサヘキサエン酸含有藻類の培養方法
JPH0787959A (ja) * 1993-09-24 1995-04-04 Kawasaki Steel Corp 海洋性微細藻類の培養方法
JPH08294384A (ja) * 1995-04-27 1996-11-12 Kawasaki Steel Corp 海洋性微細藻類のシード培養方法
EP1785492B1 (en) 1996-07-23 2010-05-26 Nagase Chemtex Corporation Process for preparing docosahexaenoic acid and docosapentaenoic acid
ES2446982T3 (es) 1996-12-27 2014-03-11 Suntory Holdings Limited Medios para cultivar microorganismos y método para producir ácidos grasos insaturados o lípidos que los contienen
JP4283351B2 (ja) * 1998-08-27 2009-06-24 サントリー酒類株式会社 新規な油脂組成物の製造方法および用途
KR19990046733A (ko) * 1999-04-20 1999-07-05 류성구 미생물슈도모나스에의한도코사핵사노인산(ｄｈａ)의제조방법
GB9916537D0 (en) * 1999-07-14 1999-09-15 Univ Hull Culture of microorganisms for the synthesis of a polyunsaturated fatty acid
KR20100051131A (ko) 2000-01-19 2010-05-14 마텍 바이오싸이언스스 코포레이션 무용매 추출 방법
EP1707055A3 (en) 2000-01-28 2009-01-14 Martek Biosciences Corporation Enhanced production of lipids containing polyenoic fatty acids by very high density cultures of eukaryotic microbes in fermentors
WO2001076715A2 (en) 2000-04-12 2001-10-18 Westfalia Separator Industry Gmbh Method for the fractionation of oil and polar lipid-containing native raw materials
ES2454196T3 (es) 2003-10-02 2014-04-09 Dsm Ip Assets B.V. Producción de niveles altos de DHA en microalgas utilizando cantidades modificadas de cloruro y potasio

Also Published As

Publication number Publication date
JP2007527233A (ja) 2007-09-27
KR101180594B1 (ko) 2012-09-06
US20160108443A1 (en) 2016-04-21
CN101386873A (zh) 2009-03-18
US20050112736A1 (en) 2005-05-26
MX338455B (es) 2016-04-18
HK1199289A1 (en) 2015-06-26
NO20061916L (no) 2006-06-12
KR20150125731A (ko) 2015-11-09
KR20140006109A (ko) 2014-01-15
KR20060097009A (ko) 2006-09-13
EP2759599A3 (en) 2014-12-10
US8663953B2 (en) 2014-03-04
US7871809B2 (en) 2011-01-18
US20120071677A1 (en) 2012-03-22
MX304474B (enExample) 2012-10-22
US20130150604A1 (en) 2013-06-13
US7829129B2 (en) 2010-11-09
JP4733043B2 (ja) 2011-07-27
ES2454196T3 (es) 2014-04-09
US20140142331A1 (en) 2014-05-22
US20080044865A1 (en) 2008-02-21
AU2004280575A1 (en) 2005-04-21
AU2010202691A1 (en) 2010-07-15
JP2011036261A (ja) 2011-02-24
KR101295390B1 (ko) 2013-09-17
EP1702073A1 (en) 2006-09-20
US20080044866A1 (en) 2008-02-21
MX271416B (es) 2009-10-30
CN101386873B (zh) 2014-05-07
JP2015130886A (ja) 2015-07-23
CA2801065C (en) 2020-04-28
CA2540617A1 (en) 2005-04-21
CN1890376B (zh) 2012-06-13
US7824892B2 (en) 2010-11-02
AU2010202691B2 (en) 2013-09-12
EP2759599A2 (en) 2014-07-30
AU2004280575B8 (en) 2010-05-13
JP5940194B2 (ja) 2016-06-29
US20080032355A1 (en) 2008-02-07
US20080032359A1 (en) 2008-02-07
US7252979B2 (en) 2007-08-07
MXPA06003467A (es) 2006-06-20
US8008050B2 (en) 2011-08-30
KR20140119198A (ko) 2014-10-08
US7745183B2 (en) 2010-06-29
US7163811B2 (en) 2007-01-16
HK1089482A1 (en) 2006-12-01
US8669090B2 (en) 2014-03-11
US20080032352A1 (en) 2008-02-07
CN1890376A (zh) 2007-01-03
US20080032358A1 (en) 2008-02-07
US9834799B2 (en) 2017-12-05
JP2013212126A (ja) 2013-10-17
EP1702073B1 (en) 2014-01-01
JP5466120B2 (ja) 2014-04-09
US20060100279A1 (en) 2006-05-11
US20080032357A1 (en) 2008-02-07
US20130158280A1 (en) 2013-06-20
JP5813061B2 (ja) 2015-11-17
US9249434B2 (en) 2016-02-02
MX351381B (es) 2017-10-12
CA2801065A1 (en) 2005-04-21
EP1702073A4 (en) 2011-08-24
WO2005035775A1 (en) 2005-04-21
US20080032354A1 (en) 2008-02-07
CN103834699A (zh) 2014-06-04
KR101761164B1 (ko) 2017-07-25
KR20110033283A (ko) 2011-03-30
KR20130041366A (ko) 2013-04-24
AU2004280575B2 (en) 2010-04-22
US20080032353A1 (en) 2008-02-07
US20080032356A1 (en) 2008-02-07

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