JP4707234B2 - シュードモナスｖ抗原を用いる免疫化のための組成物 - Google Patents

シュードモナスｖ抗原を用いる免疫化のための組成物 Download PDF

Info

Publication number
JP4707234B2
JP4707234B2 JP2000586362A JP2000586362A JP4707234B2 JP 4707234 B2 JP4707234 B2 JP 4707234B2 JP 2000586362 A JP2000586362 A JP 2000586362A JP 2000586362 A JP2000586362 A JP 2000586362A JP 4707234 B2 JP4707234 B2 JP 4707234B2
Authority
JP
Japan
Prior art keywords
pcrv
infection
antigen
composition
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2000586362A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002531522A5 (enExample
JP2002531522A (ja
Inventor
ダラ ダブリユー． フランク，
チモシー エル． イヤー，
テイジ サワ，
ジヤニネ ウイーナー−クロニツシ，
Original Assignee
エムシーダブリユー リサーチ フオンデーシヨン インコーポレーテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エムシーダブリユー リサーチ フオンデーシヨン インコーポレーテツド filed Critical エムシーダブリユー リサーチ フオンデーシヨン インコーポレーテツド
Publication of JP2002531522A publication Critical patent/JP2002531522A/ja
Publication of JP2002531522A5 publication Critical patent/JP2002531522A5/ja
Application granted granted Critical
Publication of JP4707234B2 publication Critical patent/JP4707234B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/104—Pseudomonadales, e.g. Pseudomonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
JP2000586362A 1998-11-25 1999-11-23 シュードモナスｖ抗原を用いる免疫化のための組成物 Expired - Fee Related JP4707234B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10995298P 1998-11-25 1998-11-25
US12679499P 1999-03-30 1999-03-30
US60/126,794 1999-03-30
US60/109,952 1999-03-30
PCT/US1999/027796 WO2000033872A2 (en) 1998-11-25 1999-11-23 Method of and compositions for immunization with the pseudomonas v antigen

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010273433A Division JP2011068672A (ja) 1998-11-25 2010-12-08 シュードモナス・アエルギノーザ感染を診断するための組成物

Publications (3)

Publication Number Publication Date
JP2002531522A JP2002531522A (ja) 2002-09-24
JP2002531522A5 JP2002531522A5 (enExample) 2007-01-25
JP4707234B2 true JP4707234B2 (ja) 2011-06-22

Family

ID=26807543

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000586362A Expired - Fee Related JP4707234B2 (ja) 1998-11-25 1999-11-23 シュードモナスｖ抗原を用いる免疫化のための組成物
JP2010273433A Ceased JP2011068672A (ja) 1998-11-25 2010-12-08 シュードモナス・アエルギノーザ感染を診断するための組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010273433A Ceased JP2011068672A (ja) 1998-11-25 2010-12-08 シュードモナス・アエルギノーザ感染を診断するための組成物

Country Status (10)

Country Link
US (2) US6309651B1 (enExample)
EP (2) EP1049488B1 (enExample)
JP (2) JP4707234B2 (enExample)
AT (2) ATE539349T1 (enExample)
AU (1) AU3580800A (enExample)
CA (1) CA2318536C (enExample)
DE (1) DE69930166T2 (enExample)
DK (1) DK1049488T3 (enExample)
ES (2) ES2255329T3 (enExample)
WO (1) WO2000033872A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2275840T3 (es) 2001-01-26 2007-06-16 Mcw Research Foundation, Inc. Metodo y composiciones para inmunizar con el antigeno v de pseudomonas.
AU2007231760B2 (en) * 2001-01-26 2009-10-29 Mcw Research Foundation, Inc. Method and compositions for immunization with the pseudomonas V antigen
EP1425300A2 (de) * 2001-09-13 2004-06-09 Medizinische Hochschule Hannover Phaenotyp bestimmende virulenzgene von pseudomonas aeruginosa zur kolonisation und persistenz in mensch, tier und pflanze, verwendungen der gene und zugehoerige proteine
WO2003058205A2 (en) * 2002-01-11 2003-07-17 Cornell Research Foundation, Inc. Methods of identifying putative effector proteins
ES2382075T3 (es) 2002-08-13 2012-06-05 Haptogen Ltd Procedimientos para el tratamiento de una enfermedad bacteriana infecciosa con un anticuerpo contra las moléculas señal derivadas de una antilactona o una lactona
AU2005207003C1 (en) * 2004-01-20 2013-06-13 Humanigen, Inc. Antibody specificity transfer using minimal essential binding determinants
GB0407008D0 (en) 2004-03-27 2004-04-28 Haptogen Ltd Methods for inducing rapid cell death (autolysis) in infectious bacteria
GB0410958D0 (en) 2004-05-15 2004-06-16 Haptogen Ltd Methods for reducing biofilm formation in infectious bacteria
US20090155279A1 (en) 2005-10-28 2009-06-18 Jiro Tanaka Pseudomonas Aeruginosa Outer Membrane Protein PA5158
US8084044B2 (en) 2006-03-30 2011-12-27 Meiji Seika Kaisha, Ltd. Pseudomonas aeruginosa outer membrane protein PA0427
US20100330100A1 (en) * 2007-06-29 2010-12-30 Meiji Seika Kaisha Ltd. Pseudomonas aeruginosa-outer membrane protein pa4710
SG186017A1 (en) * 2007-11-30 2012-12-28 Kalobios Pharmaceuticals Inc Antibodies to the pcrv antigen of pseudomonas aeruginosa
WO2009081955A1 (ja) 2007-12-25 2009-07-02 Meiji Seika Kaisha, Ltd. 緑膿菌のiii型分泌装置構成タンパク質pa1698
PL2248826T3 (pl) * 2008-01-10 2013-11-29 Shionogi & Co Przeciwciało skierowane przeciwko PcrV
CA2751433A1 (en) 2009-02-04 2010-08-12 Kalobios Pharmaceuticals, Inc. Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection
WO2010104052A1 (ja) 2009-03-11 2010-09-16 塩野義製薬株式会社 抗緑膿菌作用を有するヒト化ＰｃｒＶ抗体
EP2515935A4 (en) * 2009-12-22 2013-08-28 Kalobios Pharmaceuticals Inc METHOD FOR TREATING STAPHYLOCOCCUS INFECTION IN A PATIENT WITH PSEUDOMONAS AERUGINOSA INFECTION WITH LOW PATHOGEN LEVEL
US9701742B2 (en) * 2011-07-01 2017-07-11 The Trustees Of The University Of Pennsylvania Anti-properdin antibodies and uses thereof
SMT202000542T1 (it) 2011-11-07 2020-11-10 Medimmune Ltd Terapie di combinazione utilizzando molecole di legame anti-psl e pcrv di pseudomonas
JP2015532303A (ja) 2012-10-04 2015-11-09 ノベルメド セラピューティクス，インコーポレーテッド 溶血性疾患を治療するための補体第２経路特異的抗体
CN110028559B (zh) * 2019-04-15 2022-06-10 中国人民解放军陆军军医大学 一种铜绿假单胞菌疫苗重组蛋白及其编码基因和它们的应用
WO2021031270A1 (zh) * 2019-08-22 2021-02-25 四川大学 细菌膜囊泡及其分离制备系统和方法
EP4069312A4 (en) * 2019-12-04 2024-03-27 The Research Foundation for the State University of New York COMPOSITIONS AND METHODS FOR REDUCING OFF-TARGET TOXICITY OF ANTIBODY-DRUG CONJUGATES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3178014B2 (ja) * 1991-07-05 2001-06-18 東ソー株式会社 Ｒｎａの測定方法
US5599665A (en) * 1993-12-21 1997-02-04 Mcw Research Foundation Pseudomonas aeruginosa nucleic acids encoding exoenzyme S activity and use thereof in detecting pseudomonas aeruginosa infection

Also Published As

Publication number Publication date
CA2318536A1 (en) 2000-06-15
AU3580800A (en) 2000-06-26
CA2318536C (en) 2009-11-17
US6309651B1 (en) 2001-10-30
EP1666058B1 (en) 2011-12-28
US20040208888A1 (en) 2004-10-21
ES2255329T3 (es) 2006-06-16
DK1049488T3 (da) 2006-06-26
EP1666058A2 (en) 2006-06-07
US6827935B2 (en) 2004-12-07
ATE539349T1 (de) 2012-01-15
ATE318613T1 (de) 2006-03-15
JP2011068672A (ja) 2011-04-07
WO2000033872A9 (en) 2000-12-14
EP1049488B1 (en) 2006-03-01
ES2379801T3 (es) 2012-05-03
WO2000033872A3 (en) 2000-10-19
EP1666058A3 (en) 2008-03-12
DE69930166T2 (de) 2006-12-14
DE69930166D1 (de) 2006-04-27
WO2000033872A2 (en) 2000-06-15
JP2002531522A (ja) 2002-09-24
EP1049488A1 (en) 2000-11-08

Similar Documents

Publication Publication Date Title
JP4707234B2 (ja) シュードモナスｖ抗原を用いる免疫化のための組成物
JP4355786B2 (ja) シュードモナスｖ抗原を用いる免疫化のための方法および組成物
US20080226679A1 (en) Novel surface exposed proteins from chlamydia pneumoniae
JP2010132698A (ja) 病原性大腸菌関連タンパク質
Mahawar et al. Identification of a live attenuated vaccine candidate for tularemia prophylaxis
BRPI0309001B1 (pt) Bactérias gram-negativas atenuadas
Hatano et al. Biologic activities of antibodies to the neutral-polysaccharide component of the Pseudomonas aeruginosa lipopolysaccharide are blocked by O side chains and mucoid exopolysaccharide (alginate)
EP1029054B1 (en) Hp90: host membrane receptor for pathogenic bacteria, encoded by the bacterial tir gene
AU2007231760B2 (en) Method and compositions for immunization with the pseudomonas V antigen
WO2006113907A2 (en) Escherichia coli o157:h7 proteins and uses thereof
US7208574B1 (en) Host receptor for pathogenic bacteria
US20090104185A1 (en) Methods and Compositions for Mycoplasma Toxins
AU2002240125A1 (en) Method and compositions for immunization with the pseudomonas V antigen
Zeng Molecular and immunological analysis of PomA, an OmpA-like protein, of Pasteurella haemolytica serotype 1
Prommajan Production and characterization of monoclonal antibodies against listeria monocytogenes
WO2006110367A2 (en) Methods and compositions for mycoplasma toxins
WO2000062069A1 (en) Method of detecting intimin-expressing microorganisms

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20000726

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20061120

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20061120

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20061121

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100119

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100415

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100507

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100519

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100615

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100617

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100817

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20101208

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20110215

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110308

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110315

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees