DK1049488T3 - Fremgangsmåde og præparat til immunisering med Pseudomonas aeruginosa-V-antigenet - Google Patents
Fremgangsmåde og præparat til immunisering med Pseudomonas aeruginosa-V-antigenetInfo
- Publication number
- DK1049488T3 DK1049488T3 DK99971223T DK99971223T DK1049488T3 DK 1049488 T3 DK1049488 T3 DK 1049488T3 DK 99971223 T DK99971223 T DK 99971223T DK 99971223 T DK99971223 T DK 99971223T DK 1049488 T3 DK1049488 T3 DK 1049488T3
- Authority
- DK
- Denmark
- Prior art keywords
- pseudomonas aeruginosa
- antigen
- immunization
- preparation
- moderating
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 241000589517 Pseudomonas aeruginosa Species 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 230000003053 immunization Effects 0.000 title 1
- 238000002649 immunization Methods 0.000 title 1
- 208000032536 Pseudomonas Infections Diseases 0.000 abstract 1
- 108010025813 Pseudomonas antigen V Proteins 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10995298P | 1998-11-25 | 1998-11-25 | |
| US12679499P | 1999-03-30 | 1999-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1049488T3 true DK1049488T3 (da) | 2006-06-26 |
Family
ID=26807543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99971223T DK1049488T3 (da) | 1998-11-25 | 1999-11-23 | Fremgangsmåde og præparat til immunisering med Pseudomonas aeruginosa-V-antigenet |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6309651B1 (enExample) |
| EP (2) | EP1049488B1 (enExample) |
| JP (2) | JP4707234B2 (enExample) |
| AT (2) | ATE539349T1 (enExample) |
| AU (1) | AU3580800A (enExample) |
| CA (1) | CA2318536C (enExample) |
| DE (1) | DE69930166T2 (enExample) |
| DK (1) | DK1049488T3 (enExample) |
| ES (2) | ES2255329T3 (enExample) |
| WO (1) | WO2000033872A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2275840T3 (es) | 2001-01-26 | 2007-06-16 | Mcw Research Foundation, Inc. | Metodo y composiciones para inmunizar con el antigeno v de pseudomonas. |
| AU2007231760B2 (en) * | 2001-01-26 | 2009-10-29 | Mcw Research Foundation, Inc. | Method and compositions for immunization with the pseudomonas V antigen |
| EP1425300A2 (de) * | 2001-09-13 | 2004-06-09 | Medizinische Hochschule Hannover | Phaenotyp bestimmende virulenzgene von pseudomonas aeruginosa zur kolonisation und persistenz in mensch, tier und pflanze, verwendungen der gene und zugehoerige proteine |
| WO2003058205A2 (en) * | 2002-01-11 | 2003-07-17 | Cornell Research Foundation, Inc. | Methods of identifying putative effector proteins |
| ES2382075T3 (es) | 2002-08-13 | 2012-06-05 | Haptogen Ltd | Procedimientos para el tratamiento de una enfermedad bacteriana infecciosa con un anticuerpo contra las moléculas señal derivadas de una antilactona o una lactona |
| AU2005207003C1 (en) * | 2004-01-20 | 2013-06-13 | Humanigen, Inc. | Antibody specificity transfer using minimal essential binding determinants |
| GB0407008D0 (en) | 2004-03-27 | 2004-04-28 | Haptogen Ltd | Methods for inducing rapid cell death (autolysis) in infectious bacteria |
| GB0410958D0 (en) | 2004-05-15 | 2004-06-16 | Haptogen Ltd | Methods for reducing biofilm formation in infectious bacteria |
| US20090155279A1 (en) | 2005-10-28 | 2009-06-18 | Jiro Tanaka | Pseudomonas Aeruginosa Outer Membrane Protein PA5158 |
| US8084044B2 (en) | 2006-03-30 | 2011-12-27 | Meiji Seika Kaisha, Ltd. | Pseudomonas aeruginosa outer membrane protein PA0427 |
| US20100330100A1 (en) * | 2007-06-29 | 2010-12-30 | Meiji Seika Kaisha Ltd. | Pseudomonas aeruginosa-outer membrane protein pa4710 |
| SG186017A1 (en) * | 2007-11-30 | 2012-12-28 | Kalobios Pharmaceuticals Inc | Antibodies to the pcrv antigen of pseudomonas aeruginosa |
| WO2009081955A1 (ja) | 2007-12-25 | 2009-07-02 | Meiji Seika Kaisha, Ltd. | 緑膿菌のiii型分泌装置構成タンパク質pa1698 |
| PL2248826T3 (pl) * | 2008-01-10 | 2013-11-29 | Shionogi & Co | Przeciwciało skierowane przeciwko PcrV |
| CA2751433A1 (en) | 2009-02-04 | 2010-08-12 | Kalobios Pharmaceuticals, Inc. | Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection |
| WO2010104052A1 (ja) | 2009-03-11 | 2010-09-16 | 塩野義製薬株式会社 | 抗緑膿菌作用を有するヒト化ＰｃｒＶ抗体 |
| EP2515935A4 (en) * | 2009-12-22 | 2013-08-28 | Kalobios Pharmaceuticals Inc | METHOD FOR TREATING STAPHYLOCOCCUS INFECTION IN A PATIENT WITH PSEUDOMONAS AERUGINOSA INFECTION WITH LOW PATHOGEN LEVEL |
| US9701742B2 (en) * | 2011-07-01 | 2017-07-11 | The Trustees Of The University Of Pennsylvania | Anti-properdin antibodies and uses thereof |
| SMT202000542T1 (it) | 2011-11-07 | 2020-11-10 | Medimmune Ltd | Terapie di combinazione utilizzando molecole di legame anti-psl e pcrv di pseudomonas |
| JP2015532303A (ja) | 2012-10-04 | 2015-11-09 | ノベルメド セラピューティクス，インコーポレーテッド | 溶血性疾患を治療するための補体第２経路特異的抗体 |
| CN110028559B (zh) * | 2019-04-15 | 2022-06-10 | 中国人民解放军陆军军医大学 | 一种铜绿假单胞菌疫苗重组蛋白及其编码基因和它们的应用 |
| WO2021031270A1 (zh) * | 2019-08-22 | 2021-02-25 | 四川大学 | 细菌膜囊泡及其分离制备系统和方法 |
| EP4069312A4 (en) * | 2019-12-04 | 2024-03-27 | The Research Foundation for the State University of New York | COMPOSITIONS AND METHODS FOR REDUCING OFF-TARGET TOXICITY OF ANTIBODY-DRUG CONJUGATES |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3178014B2 (ja) * | 1991-07-05 | 2001-06-18 | 東ソー株式会社 | Ｒｎａの測定方法 |
| US5599665A (en) * | 1993-12-21 | 1997-02-04 | Mcw Research Foundation | Pseudomonas aeruginosa nucleic acids encoding exoenzyme S activity and use thereof in detecting pseudomonas aeruginosa infection |
-
1999
- 1999-11-23 ES ES99971223T patent/ES2255329T3/es not_active Expired - Lifetime
- 1999-11-23 JP JP2000586362A patent/JP4707234B2/ja not_active Expired - Fee Related
- 1999-11-23 EP EP99971223A patent/EP1049488B1/en not_active Expired - Lifetime
- 1999-11-23 US US09/448,339 patent/US6309651B1/en not_active Expired - Lifetime
- 1999-11-23 WO PCT/US1999/027796 patent/WO2000033872A2/en not_active Ceased
- 1999-11-23 CA CA002318536A patent/CA2318536C/en not_active Expired - Fee Related
- 1999-11-23 EP EP06000111A patent/EP1666058B1/en not_active Expired - Lifetime
- 1999-11-23 AT AT06000111T patent/ATE539349T1/de active
- 1999-11-23 DE DE69930166T patent/DE69930166T2/de not_active Expired - Lifetime
- 1999-11-23 AT AT99971223T patent/ATE318613T1/de not_active IP Right Cessation
- 1999-11-23 DK DK99971223T patent/DK1049488T3/da active
- 1999-11-23 ES ES06000111T patent/ES2379801T3/es not_active Expired - Lifetime
- 1999-11-23 AU AU35808/00A patent/AU3580800A/en not_active Abandoned
-
2001
- 2001-01-26 US US09/770,916 patent/US6827935B2/en not_active Expired - Lifetime
-
2010
- 2010-12-08 JP JP2010273433A patent/JP2011068672A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2318536A1 (en) | 2000-06-15 |
| AU3580800A (en) | 2000-06-26 |
| CA2318536C (en) | 2009-11-17 |
| US6309651B1 (en) | 2001-10-30 |
| EP1666058B1 (en) | 2011-12-28 |
| US20040208888A1 (en) | 2004-10-21 |
| ES2255329T3 (es) | 2006-06-16 |
| EP1666058A2 (en) | 2006-06-07 |
| US6827935B2 (en) | 2004-12-07 |
| ATE539349T1 (de) | 2012-01-15 |
| ATE318613T1 (de) | 2006-03-15 |
| JP2011068672A (ja) | 2011-04-07 |
| WO2000033872A9 (en) | 2000-12-14 |
| EP1049488B1 (en) | 2006-03-01 |
| JP4707234B2 (ja) | 2011-06-22 |
| ES2379801T3 (es) | 2012-05-03 |
| WO2000033872A3 (en) | 2000-10-19 |
| EP1666058A3 (en) | 2008-03-12 |
| DE69930166T2 (de) | 2006-12-14 |
| DE69930166D1 (de) | 2006-04-27 |
| WO2000033872A2 (en) | 2000-06-15 |
| JP2002531522A (ja) | 2002-09-24 |
| EP1049488A1 (en) | 2000-11-08 |
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