ES2255329T3 - Metodo y composiciones para inmunizacion con el antigeno v de pseudomonas aeruginosa. - Google Patents
Metodo y composiciones para inmunizacion con el antigeno v de pseudomonas aeruginosa.Info
- Publication number
- ES2255329T3 ES2255329T3 ES99971223T ES99971223T ES2255329T3 ES 2255329 T3 ES2255329 T3 ES 2255329T3 ES 99971223 T ES99971223 T ES 99971223T ES 99971223 T ES99971223 T ES 99971223T ES 2255329 T3 ES2255329 T3 ES 2255329T3
- Authority
- ES
- Spain
- Prior art keywords
- pcrv
- infection
- antigen
- pseudomonas aeruginosa
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10995298P | 1998-11-25 | 1998-11-25 | |
| US109952P | 1998-11-25 | ||
| US12679499P | 1999-03-30 | 1999-03-30 | |
| US126794P | 1999-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2255329T3 true ES2255329T3 (es) | 2006-06-16 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99971223T Expired - Lifetime ES2255329T3 (es) | 1998-11-25 | 1999-11-23 | Metodo y composiciones para inmunizacion con el antigeno v de pseudomonas aeruginosa. |
| ES06000111T Expired - Lifetime ES2379801T3 (es) | 1998-11-25 | 1999-11-23 | Método para diagnosticar una infección por pseudomonas aeruginosa |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES06000111T Expired - Lifetime ES2379801T3 (es) | 1998-11-25 | 1999-11-23 | Método para diagnosticar una infección por pseudomonas aeruginosa |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6309651B1 (enExample) |
| EP (2) | EP1666058B1 (enExample) |
| JP (2) | JP4707234B2 (enExample) |
| AT (2) | ATE539349T1 (enExample) |
| AU (1) | AU3580800A (enExample) |
| CA (1) | CA2318536C (enExample) |
| DE (1) | DE69930166T2 (enExample) |
| DK (1) | DK1049488T3 (enExample) |
| ES (2) | ES2255329T3 (enExample) |
| WO (1) | WO2000033872A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007231760B2 (en) * | 2001-01-26 | 2009-10-29 | Mcw Research Foundation, Inc. | Method and compositions for immunization with the pseudomonas V antigen |
| WO2002064161A2 (en) * | 2001-01-26 | 2002-08-22 | Mcw Research Foundation, Inc. | Method and compositions for immunization with the pseudomonas v antigen |
| DE10294091D2 (de) * | 2001-09-13 | 2004-08-05 | Hannover Med Hochschule | Phänotyp bestimmende Virulenzgene von Pseudomonas aeruginosa zur Kolonisation und Persistenz in Mensch, Tier und Pflanze, Verwendungen der Gene und zugehörigen Proteine |
| WO2003058205A2 (en) * | 2002-01-11 | 2003-07-17 | Cornell Research Foundation, Inc. | Methods of identifying putative effector proteins |
| CA2495725C (en) | 2002-08-13 | 2013-06-25 | Haptogen Ltd | Methods for the treatment of an infectious bacterial disease with an anti-lactone or lactone derived signal molecules antibody |
| JP4782700B2 (ja) * | 2004-01-20 | 2011-09-28 | カロバイオス ファーマシューティカルズ インコーポレイティッド | 最低限必須な結合決定基を用いた抗体特異性の移入 |
| GB0407008D0 (en) | 2004-03-27 | 2004-04-28 | Haptogen Ltd | Methods for inducing rapid cell death (autolysis) in infectious bacteria |
| GB0410958D0 (en) | 2004-05-15 | 2004-06-16 | Haptogen Ltd | Methods for reducing biofilm formation in infectious bacteria |
| EP1946768A4 (en) | 2005-10-28 | 2009-11-11 | Meiji Seika Kaisha | OUTER COAT PROTEIN PA5158 OF PSEUDOMONAS AERUGINOSA |
| AU2007232894B2 (en) | 2006-03-30 | 2013-01-31 | Meiji Seika Kaisha, Ltd. | Pseudomonas aeruginosa outer membrane protein PA0427 |
| CN101878302A (zh) * | 2007-06-29 | 2010-11-03 | 明治制果株式会社 | 绿脓杆菌的外膜蛋白质pa4710 |
| EA201000903A1 (ru) * | 2007-11-30 | 2011-02-28 | Калобиос Фармасьютикалс, Инк. | Антитела к pcrv-антигену pseudomonas aeruginosa |
| CA2709500A1 (en) | 2007-12-25 | 2009-07-02 | Meiji Seika Kaisha, Ltd. | Type iii secretion system component protein pa1698 of pseudomonas aeruginosa |
| BRPI0906810A2 (pt) * | 2008-01-10 | 2019-10-01 | Shionogi & Co | anticorpo contra pcrv |
| EP2393515A1 (en) | 2009-02-04 | 2011-12-14 | Kalobios Pharmaceuticals, Inc. | Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection |
| KR101686261B1 (ko) | 2009-03-11 | 2016-12-14 | 시오노기세야쿠 가부시키가이샤 | 항녹농균 작용을 갖는 인간화 ＰｃｒＶ 항체 |
| WO2011087799A1 (en) * | 2009-12-22 | 2011-07-21 | Kalobios Pharmaceuticals, Inc. | A method of treating a staphylococcus infection in a patient having a low-level pathogenic pseudomonas aeruginosa infection |
| EP2726103B1 (en) * | 2011-07-01 | 2018-09-05 | The Trustees Of The University Of Pennsylvania | Anti-properdin antibodies and uses thereof |
| BR112014011028B1 (pt) | 2011-11-07 | 2021-03-02 | Medimmune, Llc | anticorpo biespecífico, composição, e, uso da composição |
| US9926366B2 (en) | 2012-10-04 | 2018-03-27 | Novelmed Therapeutics, Inc. | Methods of treating a hemolytic disorder comprising administering anti-properdin antibodies |
| CN110028559B (zh) * | 2019-04-15 | 2022-06-10 | 中国人民解放军陆军军医大学 | 一种铜绿假单胞菌疫苗重组蛋白及其编码基因和它们的应用 |
| WO2021031270A1 (zh) * | 2019-08-22 | 2021-02-25 | 四川大学 | 细菌膜囊泡及其分离制备系统和方法 |
| WO2021113740A1 (en) * | 2019-12-04 | 2021-06-10 | The Research Foundation For The State University Of New York | Compositions and methods for reducing off-target toxicity of antibody drug conjugates |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3178014B2 (ja) * | 1991-07-05 | 2001-06-18 | 東ソー株式会社 | Ｒｎａの測定方法 |
| US5599665A (en) | 1993-12-21 | 1997-02-04 | Mcw Research Foundation | Pseudomonas aeruginosa nucleic acids encoding exoenzyme S activity and use thereof in detecting pseudomonas aeruginosa infection |
-
1999
- 1999-11-23 CA CA002318536A patent/CA2318536C/en not_active Expired - Fee Related
- 1999-11-23 EP EP06000111A patent/EP1666058B1/en not_active Expired - Lifetime
- 1999-11-23 EP EP99971223A patent/EP1049488B1/en not_active Expired - Lifetime
- 1999-11-23 AU AU35808/00A patent/AU3580800A/en not_active Abandoned
- 1999-11-23 WO PCT/US1999/027796 patent/WO2000033872A2/en not_active Ceased
- 1999-11-23 DE DE69930166T patent/DE69930166T2/de not_active Expired - Lifetime
- 1999-11-23 JP JP2000586362A patent/JP4707234B2/ja not_active Expired - Fee Related
- 1999-11-23 AT AT06000111T patent/ATE539349T1/de active
- 1999-11-23 ES ES99971223T patent/ES2255329T3/es not_active Expired - Lifetime
- 1999-11-23 ES ES06000111T patent/ES2379801T3/es not_active Expired - Lifetime
- 1999-11-23 US US09/448,339 patent/US6309651B1/en not_active Expired - Lifetime
- 1999-11-23 AT AT99971223T patent/ATE318613T1/de not_active IP Right Cessation
- 1999-11-23 DK DK99971223T patent/DK1049488T3/da active
-
2001
- 2001-01-26 US US09/770,916 patent/US6827935B2/en not_active Expired - Lifetime
-
2010
- 2010-12-08 JP JP2010273433A patent/JP2011068672A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2318536A1 (en) | 2000-06-15 |
| WO2000033872A2 (en) | 2000-06-15 |
| US20040208888A1 (en) | 2004-10-21 |
| DE69930166D1 (de) | 2006-04-27 |
| EP1666058B1 (en) | 2011-12-28 |
| JP2002531522A (ja) | 2002-09-24 |
| WO2000033872A3 (en) | 2000-10-19 |
| WO2000033872A9 (en) | 2000-12-14 |
| EP1666058A3 (en) | 2008-03-12 |
| ES2379801T3 (es) | 2012-05-03 |
| DE69930166T2 (de) | 2006-12-14 |
| AU3580800A (en) | 2000-06-26 |
| EP1049488B1 (en) | 2006-03-01 |
| JP4707234B2 (ja) | 2011-06-22 |
| ATE539349T1 (de) | 2012-01-15 |
| DK1049488T3 (da) | 2006-06-26 |
| EP1666058A2 (en) | 2006-06-07 |
| US6827935B2 (en) | 2004-12-07 |
| US6309651B1 (en) | 2001-10-30 |
| CA2318536C (en) | 2009-11-17 |
| ATE318613T1 (de) | 2006-03-15 |
| JP2011068672A (ja) | 2011-04-07 |
| EP1049488A1 (en) | 2000-11-08 |
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