JP4624566B2 - 高密度の細胞を産生および使用するための装置および方法およびそこからの産物 - Google Patents

高密度の細胞を産生および使用するための装置および方法およびそこからの産物 Download PDF

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JP4624566B2
JP4624566B2 JP2000597414A JP2000597414A JP4624566B2 JP 4624566 B2 JP4624566 B2 JP 4624566B2 JP 2000597414 A JP2000597414 A JP 2000597414A JP 2000597414 A JP2000597414 A JP 2000597414A JP 4624566 B2 JP4624566 B2 JP 4624566B2
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cells
oxygen
cell
bioreactor
cell culture
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イー スミス,ゲイル
ネル,ジョン
アイ ヴォツネゼンスキー,アンドレイ
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プロテイン サイエンシーズ コーポレイション
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    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
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    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06Nozzles; Sprayers; Spargers; Diffusers
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    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16Hollow fibers
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    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18External loop; Means for reintroduction of fermented biomass or liquid percolate
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    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/26Conditioning fluids entering or exiting the reaction vessel
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    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
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    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
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    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
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    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements

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  • Chemical & Material Sciences (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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JP2000597414A 1999-02-05 2000-01-21 高密度の細胞を産生および使用するための装置および方法およびそこからの産物 Expired - Fee Related JP4624566B2 (ja)

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Application Number Priority Date Filing Date Title
US11881699P 1999-02-05 1999-02-05
US60/118,816 1999-02-05
US16235499P 1999-10-29 1999-10-29
US60/162,354 1999-10-29
US09/484,886 US8026096B1 (en) 1998-10-08 2000-01-18 In vivo active erythropoietin produced in insect cells
US09/484,886 2000-01-18
PCT/US2000/001568 WO2000046354A1 (en) 1999-02-05 2000-01-21 Apparatus and methods for producing and using high-density cells and products therefrom

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JP2003521877A JP2003521877A (ja) 2003-07-22
JP2003521877A5 JP2003521877A5 (https=) 2007-03-15
JP4624566B2 true JP4624566B2 (ja) 2011-02-02

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US (3) US8026096B1 (https=)
EP (1) EP1157098B1 (https=)
JP (1) JP4624566B2 (https=)
AT (1) ATE408673T1 (https=)
CA (1) CA2360916C (https=)
DE (1) DE60040271D1 (https=)
DK (1) DK1157098T3 (https=)
HK (1) HK1043153B (https=)
WO (1) WO2000046354A1 (https=)

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WO2000046354A8 (en) 2001-07-12
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US20100159524A1 (en) 2010-06-24
US20060019385A1 (en) 2006-01-26
US7879601B2 (en) 2011-02-01
US8026096B1 (en) 2011-09-27
ATE408673T1 (de) 2008-10-15
EP1157098A1 (en) 2001-11-28
US7598075B2 (en) 2009-10-06
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