JP4612262B2 - ミクロ分析装置 - Google Patents

ミクロ分析装置 Download PDF

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Publication number
JP4612262B2
JP4612262B2 JP2001546961A JP2001546961A JP4612262B2 JP 4612262 B2 JP4612262 B2 JP 4612262B2 JP 2001546961 A JP2001546961 A JP 2001546961A JP 2001546961 A JP2001546961 A JP 2001546961A JP 4612262 B2 JP4612262 B2 JP 4612262B2
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JP
Japan
Prior art keywords
fluid
chamber
arm
shaped chamber
shaped
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2001546961A
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English (en)
Japanese (ja)
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JP2003518250A5 (enExample
JP2003518250A (ja
Inventor
ペール・アンデション
アルヴィ・アクスバリィ
グンナー・エクストランド
ビエルン・バリィ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gyros Patent AB
Original Assignee
Gyros Patent AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1999/010347 external-priority patent/WO2000040750A1/en
Application filed by Gyros Patent AB filed Critical Gyros Patent AB
Publication of JP2003518250A publication Critical patent/JP2003518250A/ja
Publication of JP2003518250A5 publication Critical patent/JP2003518250A5/ja
Application granted granted Critical
Publication of JP4612262B2 publication Critical patent/JP4612262B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Centrifugal Separators (AREA)
JP2001546961A 1999-12-23 2000-12-22 ミクロ分析装置 Expired - Lifetime JP4612262B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/EP1999/010347 WO2000040750A1 (en) 1998-12-30 1999-12-23 Method for sequencing dna using a microfluidic device
EP99/10347 1999-12-23
SE0001779A SE0001779D0 (sv) 2000-05-12 2000-05-12 Microanalysis device
SE0001779-8 2000-05-12
PCT/EP2000/013145 WO2001046465A2 (en) 1999-12-23 2000-12-22 Microfluid analysis device

Publications (3)

Publication Number Publication Date
JP2003518250A JP2003518250A (ja) 2003-06-03
JP2003518250A5 JP2003518250A5 (enExample) 2008-02-28
JP4612262B2 true JP4612262B2 (ja) 2011-01-12

Family

ID=20279665

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001546961A Expired - Lifetime JP4612262B2 (ja) 1999-12-23 2000-12-22 ミクロ分析装置

Country Status (7)

Country Link
JP (1) JP4612262B2 (enExample)
AT (1) ATE367204T1 (enExample)
AU (1) AU4410501A (enExample)
CA (1) CA2395159A1 (enExample)
DE (1) DE60035611T2 (enExample)
SE (1) SE0001779D0 (enExample)
WO (1) WO2001046465A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7087203B2 (en) 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
US7026131B2 (en) 2000-11-17 2006-04-11 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-discs
SE0004297D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device for thermal cycling
SE0004296D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
US7054258B2 (en) 2000-12-08 2006-05-30 Nagaoka & Co., Ltd. Optical disc assemblies for performing assays
US7079468B2 (en) 2000-12-08 2006-07-18 Burstein Technologies, Inc. Optical discs for measuring analytes
US7091034B2 (en) 2000-12-15 2006-08-15 Burstein Technologies, Inc. Detection system for disk-based laboratory and improved optical bio-disc including same
US7759067B2 (en) 2001-03-19 2010-07-20 Gyros Patent Ab Method for determining the amount of an analyte with a disc-shaped microfluidic device
US7429354B2 (en) 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
EP1483052B1 (en) * 2001-08-28 2010-12-22 Gyros Patent Ab Retaining microfluidic microcavity and other microfluidic structures
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
JP4368681B2 (ja) * 2001-09-17 2009-11-18 ユィロス・パテント・アクチボラグ マイクロ流体デバイス内の流れの制御を可能にする機能ユニット
ATE477054T1 (de) 2001-09-17 2010-08-15 Gyros Patent Ab Einen kontrollierten strom in einer mikrofluidvorrichtung ermöglichende funktionseinheit
US7662340B2 (en) * 2001-12-28 2010-02-16 Hitachi High-Technologies Corporation Extractor chemical analyzer and chemical analyzing method
JP4338529B2 (ja) 2002-04-08 2009-10-07 ユロス・パテント・アクチボラゲット ホーミングプロセス
AU2003224586A1 (en) * 2002-04-30 2003-11-17 Gyros Ab Integrated microfluidic device (ea)
WO2003093836A1 (fr) * 2002-04-30 2003-11-13 Arkray, Inc. Instrument d'analyse, procede d'analyse d'echantillon et dispositif d'analyse utilisant un tel instrument, procede de formation d'ouverture dans l'instrument
US7005265B1 (en) 2002-06-20 2006-02-28 Wenhong Fan Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays
JP4575162B2 (ja) 2002-10-13 2010-11-04 ピコセプ アクティーゼルスカブ 二次元ミクロ流体生体分子分離システム
SE0301945D0 (sv) 2003-06-30 2003-06-30 Gyros Ab Confidence determination
US20060210426A1 (en) * 2003-08-05 2006-09-21 Taiyo Yuden Co., Ltd. Sample analyzer and disk-like sample analyzing medium
JP2007524849A (ja) * 2004-01-06 2007-08-30 ユィロス・パテント・アクチボラグ 接触加熱アレンジメント
US7947235B2 (en) 2005-04-14 2011-05-24 Gyros Ab Microfluidic device with finger valves
GB2464721C (en) 2008-10-23 2013-08-14 Biosurfit Sa Jet deflection device
GB2466644B (en) 2008-12-30 2011-05-11 Biosurfit Sa Liquid handling
JP5521454B2 (ja) * 2009-09-15 2014-06-11 凸版印刷株式会社 試料分析チップ、これを用いた試料分析装置及び試料分析方法
GB2476474B (en) 2009-12-22 2012-03-28 Biosurfit Sa Surface plasmon resonance detection system
GB2479139A (en) 2010-03-29 2011-10-05 Biosurfit Sa A liquid distribution and metering device
EP2486978A1 (de) 2010-10-28 2012-08-15 Roche Diagnostics GmbH Mikrofluidischer Testträger zum Aufteilen einer Flüssigkeitsmenge in Teilmengen
EP2455162A1 (de) 2010-10-29 2012-05-23 Roche Diagnostics GmbH Mikrofluidisches Element zur Analyse einer Probenflüssigkeit
JP6257521B2 (ja) 2011-12-08 2018-01-10 バイオサーフィット、 ソシエダッド アノニマ 逐次分注および沈降速度の指標の決定
JP5549719B2 (ja) * 2012-09-20 2014-07-16 ブラザー工業株式会社 検査対象受体
US9993819B2 (en) 2014-12-30 2018-06-12 Stmicroelectronics S.R.L. Apparatus for actuating and reading a centrifugal microfluidic disk for biological and biochemical analyses, and use of the apparatus
WO2017154750A1 (ja) * 2016-03-11 2017-09-14 パナソニック株式会社 液体試料検査用ディスク及びそれに用いるフィルタカートリッジ、ディスク本体、測定用プレート、試料検出プレート、蛍光検出システム及び蛍光検出方法

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US3547547A (en) * 1969-03-13 1970-12-15 Atomic Energy Commission Analytical photometer with means for measuring,holding and transferring discrete liquid volumes and method of use thereof
US4284602A (en) * 1979-12-10 1981-08-18 Immutron, Inc. Integrated fluid manipulator
US4632908A (en) * 1984-05-03 1986-12-30 Abbott Laboratories Heating system for rotating members
US5160702A (en) * 1989-01-17 1992-11-03 Molecular Devices Corporation Analyzer with improved rotor structure
US5230866A (en) * 1991-03-01 1993-07-27 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
AU4047493A (en) * 1992-04-02 1993-11-08 Abaxis, Inc. Analytical rotor with dye mixing chamber
US5591643A (en) * 1993-09-01 1997-01-07 Abaxis, Inc. Simplified inlet channels
US6299839B1 (en) * 1995-08-31 2001-10-09 First Medical, Inc. System and methods for performing rotor assays
AU734957B2 (en) * 1997-05-16 2001-06-28 Alberta Research Council Inc. Microfluidic system and methods of use
EP0983504A2 (en) * 1997-05-23 2000-03-08 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US5919711A (en) * 1997-08-07 1999-07-06 Careside, Inc. Analytical cartridge
US5916522A (en) * 1997-08-07 1999-06-29 Careside, Inc. Electrochemical analytical cartridge
GB9828785D0 (en) * 1998-12-30 1999-02-17 Amersham Pharm Biotech Ab Sequencing systems

Also Published As

Publication number Publication date
ATE367204T1 (de) 2007-08-15
DE60035611D1 (de) 2007-08-30
DE60035611T2 (de) 2008-05-21
JP2003518250A (ja) 2003-06-03
AU4410501A (en) 2001-07-03
WO2001046465A3 (en) 2001-12-27
CA2395159A1 (en) 2001-06-28
WO2001046465A2 (en) 2001-06-28
SE0001779D0 (sv) 2000-05-12

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