JP4608217B2 - 不整脈の治療法 - Google Patents

不整脈の治療法 Download PDF

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Publication number
JP4608217B2
JP4608217B2 JP2003583420A JP2003583420A JP4608217B2 JP 4608217 B2 JP4608217 B2 JP 4608217B2 JP 2003583420 A JP2003583420 A JP 2003583420A JP 2003583420 A JP2003583420 A JP 2003583420A JP 4608217 B2 JP4608217 B2 JP 4608217B2
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JP
Japan
Prior art keywords
ranolazine
compound
isomer
formula
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2003583420A
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English (en)
Japanese (ja)
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JP2005528393A5 (https=
JP2005528393A (ja
Inventor
ルイス・ベラルディネッリ
チャールズ・アンツェレビッチ
ブレント・ブラックバーン
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Gilead Palo Alto Inc
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Gilead Palo Alto Inc
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Publication of JP2005528393A publication Critical patent/JP2005528393A/ja
Publication of JP2005528393A5 publication Critical patent/JP2005528393A5/ja
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Publication of JP4608217B2 publication Critical patent/JP4608217B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2003583420A 2002-04-04 2003-04-04 不整脈の治療法 Expired - Fee Related JP4608217B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37015002P 2002-04-04 2002-04-04
US40829202P 2002-09-05 2002-09-05
US42258902P 2002-10-30 2002-10-30
PCT/US2003/010434 WO2003086401A1 (en) 2002-04-04 2003-04-04 Use of ranolazine for the preparation of a medicament for the treatment of arrhythmias

Publications (3)

Publication Number Publication Date
JP2005528393A JP2005528393A (ja) 2005-09-22
JP2005528393A5 JP2005528393A5 (https=) 2006-05-11
JP4608217B2 true JP4608217B2 (ja) 2011-01-12

Family

ID=29255318

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003583420A Expired - Fee Related JP4608217B2 (ja) 2002-04-04 2003-04-04 不整脈の治療法

Country Status (19)

Country Link
US (2) US20030220344A1 (https=)
EP (3) EP2198866A1 (https=)
JP (1) JP4608217B2 (https=)
KR (2) KR20100119804A (https=)
CN (2) CN100548300C (https=)
AT (2) ATE470445T1 (https=)
AU (3) AU2003230810B2 (https=)
CA (1) CA2481192C (https=)
CY (1) CY1110400T1 (https=)
DE (2) DE60321550D1 (https=)
DK (2) DK1930007T3 (https=)
ES (2) ES2345573T3 (https=)
IL (1) IL197406A0 (https=)
MX (1) MXPA04009637A (https=)
NO (1) NO330953B1 (https=)
NZ (1) NZ535610A (https=)
PT (2) PT1490066E (https=)
SI (2) SI1490066T1 (https=)
WO (1) WO2003086401A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10925546B2 (en) 2015-01-09 2021-02-23 Industry-Academic Cooperation Foundation Yonsei University System and method for evaluating effects of antiarrhythmic agent

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US10925546B2 (en) 2015-01-09 2021-02-23 Industry-Academic Cooperation Foundation Yonsei University System and method for evaluating effects of antiarrhythmic agent

Also Published As

Publication number Publication date
EP2198866A1 (en) 2010-06-23
AU2003230810B2 (en) 2009-02-26
EP1930007A1 (en) 2008-06-11
NZ535610A (en) 2006-05-26
AU2009201065B2 (en) 2011-07-21
IL197406A0 (en) 2011-07-31
NO330953B1 (no) 2011-08-22
CN101843619A (zh) 2010-09-29
HK1120390A1 (en) 2009-04-03
ATE470445T1 (de) 2010-06-15
AU2003230810A1 (en) 2003-10-27
ES2304507T3 (es) 2008-10-16
WO2003086401A1 (en) 2003-10-23
AU2011202135A1 (en) 2011-05-26
CA2481192C (en) 2012-07-03
SI1490066T1 (sl) 2008-10-31
AU2009201065A1 (en) 2009-04-09
CY1110400T1 (el) 2015-04-29
DE60321550D1 (de) 2008-07-24
CN1646127A (zh) 2005-07-27
ATE397932T1 (de) 2008-07-15
CA2481192A1 (en) 2003-10-23
JP2005528393A (ja) 2005-09-22
CN100548300C (zh) 2009-10-14
SI1930007T1 (sl) 2010-08-31
DK1930007T3 (da) 2010-08-30
US20100004255A1 (en) 2010-01-07
ES2345573T3 (es) 2010-09-27
MXPA04009637A (es) 2005-07-14
EP1930007B1 (en) 2010-06-09
EP1490066B1 (en) 2008-06-11
DK1490066T3 (da) 2008-10-13
PT1490066E (pt) 2008-07-22
EP1490066A1 (en) 2004-12-29
NO20044783L (no) 2004-11-03
US20030220344A1 (en) 2003-11-27
KR20100119804A (ko) 2010-11-10
PT1930007E (pt) 2010-08-17
KR20040099395A (ko) 2004-11-26
DE60332975D1 (de) 2010-07-22

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