JP4584987B2 - C5修飾ピリミジンを含むオリゴヌクレオチド - Google Patents
C5修飾ピリミジンを含むオリゴヌクレオチド Download PDFInfo
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- JP4584987B2 JP4584987B2 JP2007511092A JP2007511092A JP4584987B2 JP 4584987 B2 JP4584987 B2 JP 4584987B2 JP 2007511092 A JP2007511092 A JP 2007511092A JP 2007511092 A JP2007511092 A JP 2007511092A JP 4584987 B2 JP4584987 B2 JP 4584987B2
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- 0 BC(C(N1)=O)=CN(*)C1=O Chemical compound BC(C(N1)=O)=CN(*)C1=O 0.000 description 13
- WEHYIISSCBSKDY-ROTTUQNMSA-N CC([C@H]1NC2=O)SC[C@@H]1N2N Chemical compound CC([C@H]1NC2=O)SC[C@@H]1N2N WEHYIISSCBSKDY-ROTTUQNMSA-N 0.000 description 1
- JQTYTARZZPXPPA-UHFFFAOYSA-N CN(C=C(C(N)=N1)Br)C1=O Chemical compound CN(C=C(C(N)=N1)Br)C1=O JQTYTARZZPXPPA-UHFFFAOYSA-N 0.000 description 1
- ZAAVRWSROWQUIU-LEWSCRJBSA-N C[C@@H]([C@H]1N2)SC[C@@H]1N(C(c1ccc(C(C)(C)C)cc1)=O)C2=O Chemical compound C[C@@H]([C@H]1N2)SC[C@@H]1N(C(c1ccc(C(C)(C)C)cc1)=O)C2=O ZAAVRWSROWQUIU-LEWSCRJBSA-N 0.000 description 1
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- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Public Health (AREA)
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- Biochemistry (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56671004P | 2004-04-30 | 2004-04-30 | |
| US62027604P | 2004-10-20 | 2004-10-20 | |
| PCT/US2005/015305 WO2006073458A2 (en) | 2004-04-30 | 2005-04-29 | Oligonucleotides comprising a c5-modified pyrimidine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007535922A JP2007535922A (ja) | 2007-12-13 |
| JP2007535922A5 JP2007535922A5 (enExample) | 2010-04-08 |
| JP4584987B2 true JP4584987B2 (ja) | 2010-11-24 |
Family
ID=36647912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007511092A Expired - Lifetime JP4584987B2 (ja) | 2004-04-30 | 2005-04-29 | C5修飾ピリミジンを含むオリゴヌクレオチド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7674778B2 (enExample) |
| EP (2) | EP1750776A2 (enExample) |
| JP (1) | JP4584987B2 (enExample) |
| AU (1) | AU2005323437B2 (enExample) |
| CA (1) | CA2562151C (enExample) |
| WO (1) | WO2006073458A2 (enExample) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6242246B1 (en) * | 1997-12-15 | 2001-06-05 | Somalogic, Inc. | Nucleic acid ligand diagnostic Biochip |
| EP1481090A4 (en) | 2002-02-15 | 2006-08-09 | Somalogic Inc | METHOD AND REAGENTS FOR DETECTING BINDING OF TARGET MOLECULES BY NUCLEIC ACID ELECTRODES |
| WO2006078278A2 (en) | 2004-04-27 | 2006-07-27 | Alnylam Pharmaceuticals, Inc. | Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety |
| HUE037173T2 (hu) * | 2006-08-08 | 2018-08-28 | Univ Bonn Rheinische Friedrich Wilhelms | 5'-Foszfát-oligonukleotidok szerkezete és alkalmazása |
| EP2088865B1 (en) * | 2006-11-06 | 2015-10-21 | Jina Pharmaceuticals Inc. | Guggulphospholipid methods and compositions |
| CA2711003C (en) * | 2006-12-29 | 2017-02-21 | Georgetown University | Targeting of ews-fli1 as anti-tumor therapy |
| US8232310B2 (en) | 2006-12-29 | 2012-07-31 | Georgetown University | Targeting of EWS-FLI1 as anti-tumor therapy |
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-
2005
- 2005-04-29 JP JP2007511092A patent/JP4584987B2/ja not_active Expired - Lifetime
- 2005-04-29 WO PCT/US2005/015305 patent/WO2006073458A2/en not_active Ceased
- 2005-04-29 US US11/119,533 patent/US7674778B2/en active Active
- 2005-04-29 AU AU2005323437A patent/AU2005323437B2/en not_active Expired
- 2005-04-29 EP EP05856684A patent/EP1750776A2/en not_active Ceased
- 2005-04-29 EP EP15002784.5A patent/EP3034510A1/en not_active Withdrawn
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2006073458A2 (en) | 2006-07-13 |
| US7674778B2 (en) | 2010-03-09 |
| CA2562151C (en) | 2016-09-06 |
| EP3034510A1 (en) | 2016-06-22 |
| AU2005323437A1 (en) | 2006-07-13 |
| WO2006073458A8 (en) | 2006-11-16 |
| AU2005323437B2 (en) | 2011-10-06 |
| US20050288244A1 (en) | 2005-12-29 |
| CA2562151A1 (en) | 2006-04-13 |
| JP2007535922A (ja) | 2007-12-13 |
| WO2006073458A3 (en) | 2008-02-21 |
| EP1750776A2 (en) | 2007-02-14 |
| AU2005323437A2 (en) | 2008-06-19 |
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