JP4564664B2 - 保持された組織検体の光学的薄断片を形成するカセット - Google Patents

保持された組織検体の光学的薄断片を形成するカセット Download PDF

Info

Publication number
JP4564664B2
JP4564664B2 JP2000600084A JP2000600084A JP4564664B2 JP 4564664 B2 JP4564664 B2 JP 4564664B2 JP 2000600084 A JP2000600084 A JP 2000600084A JP 2000600084 A JP2000600084 A JP 2000600084A JP 4564664 B2 JP4564664 B2 JP 4564664B2
Authority
JP
Japan
Prior art keywords
window
cassette
tissue specimen
membrane
base member
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2000600084A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002537573A5 (enExample
JP2002537573A (ja
Inventor
エム イーストマン，ジャイ
ジェイ フォックス，ウイリアム
ジェイ グリーンワルド，ロジャー
ピー ロエッサー，ケビン
エム ザビスラン，ジェームス
Original Assignee
ルーシド インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ルーシド インコーポレーテッド filed Critical ルーシド インコーポレーテッド
Publication of JP2002537573A publication Critical patent/JP2002537573A/ja
Publication of JP2002537573A5 publication Critical patent/JP2002537573A5/ja
Application granted granted Critical
Publication of JP4564664B2 publication Critical patent/JP4564664B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/368—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements details of associated display arrangements, e.g. mounting of LCD monitor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/0012—Surgical microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/26—Stages; Adjusting means therefor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/33—Immersion oils, or microscope systems or objectives for use with immersion fluids
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/021—Identification, e.g. bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/043—Hinged closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0609—Holders integrated in container to position an object
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N2001/315—Basket-type carriers for tissues

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Microscoopes, Condenser (AREA)
JP2000600084A 1999-02-17 2000-02-17 保持された組織検体の光学的薄断片を形成するカセット Expired - Fee Related JP4564664B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12053499P 1999-02-17 1999-02-17
US60/120,534 1999-02-17
PCT/US2000/004070 WO2000049392A1 (en) 1999-02-17 2000-02-17 Cassette for facilitating optical sectioning of a retained tissue specimen

Publications (3)

Publication Number Publication Date
JP2002537573A JP2002537573A (ja) 2002-11-05
JP2002537573A5 JP2002537573A5 (enExample) 2007-04-05
JP4564664B2 true JP4564664B2 (ja) 2010-10-20

Family

ID=22390917

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000600084A Expired - Fee Related JP4564664B2 (ja) 1999-02-17 2000-02-17 保持された組織検体の光学的薄断片を形成するカセット

Country Status (5)

Country Link
US (4) US6411434B1 (enExample)
EP (1) EP1169630B1 (enExample)
JP (1) JP4564664B2 (enExample)
AU (1) AU3493800A (enExample)
WO (1) WO2000049392A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180119257A (ko) * 2017-04-25 2018-11-02 가톨릭대학교 산학협력단 의료용 검사 슬라이드 유닛

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1121052B1 (en) * 1998-09-14 2018-07-25 Lucid, Inc. Imaging of surgical biopsies
US7227630B1 (en) * 1998-09-14 2007-06-05 Lucid, Inc. Imaging of surgical biopsies
EP1169630B1 (en) 1999-02-17 2017-02-01 Lucid, Inc. Cassette for facilitating optical sectioning of a retained tissue specimen
WO2000049447A1 (en) 1999-02-17 2000-08-24 Lucid, Inc. Tissue specimen holder
US7194118B1 (en) 2000-11-10 2007-03-20 Lucid, Inc. System for optically sectioning and mapping surgically excised tissue
US6693767B1 (en) * 2001-07-31 2004-02-17 Western Digital Technologies, Inc. Disk drive having a head disk assembly enclosure including an integrated hinge
US20070255169A1 (en) * 2001-11-19 2007-11-01 Dune Medical Devices Ltd. Clean margin assessment tool
US20040133112A1 (en) * 2002-03-08 2004-07-08 Milind Rajadhyaksha System and method for macroscopic and confocal imaging of tissue
CN100439894C (zh) 2002-09-26 2008-12-03 比欧帕斯自动化公司 用于自动处理和包埋组织标本的设备和方法
US7179424B2 (en) 2002-09-26 2007-02-20 Biopath Automation, L.L.C. Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor
WO2004028693A1 (en) 2002-09-26 2004-04-08 Biopath Automation, L.L.C. Cassette and embedding assembly, staging devices, and methods for handling tissue samples
DE10250247B4 (de) * 2002-10-28 2006-06-01 Leica Microsystems Cms Gmbh Probenträger für die Mikroskopie und Verfahren zum Anfertigen eines Probenträgers
EP2256535B1 (en) * 2004-02-16 2012-07-04 Olympus Corporation retention mechanism for immersion medium, and manufacturing method thereof
US7215431B2 (en) * 2004-03-04 2007-05-08 Therma-Wave, Inc. Systems and methods for immersion metrology
EP1774389B1 (de) * 2004-08-05 2014-06-18 JPK Instruments AG Vorrichtung zum aufnehmen einer messprobe
JP4585329B2 (ja) * 2005-02-10 2010-11-24 東芝機械株式会社 薄切片標本の作製方法及び薄切片標本
US20060227108A1 (en) * 2005-03-31 2006-10-12 Ikey, Ltd. Computer mouse for harsh environments and method of fabrication
US20070116612A1 (en) * 2005-11-02 2007-05-24 Biopath Automation, L.L.C. Prefix tissue cassette
US7864996B2 (en) * 2006-02-17 2011-01-04 Lucid, Inc. System for macroscopic and confocal imaging of tissue
US8260401B2 (en) * 2006-07-26 2012-09-04 University Of Rochester Non-invasive in-vivo imaging of mechanoreceptors in skin using confocal microscopy
US8383067B2 (en) * 2006-12-12 2013-02-26 Biopath Automation, L.L.C. Biopsy support with sectionable resilient cellular material
WO2010007509A1 (en) * 2008-07-18 2010-01-21 Leica Biosystems Newcastle Limited Method for preparing cell standard
US20100081924A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081190A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081919A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081923A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081925A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US8384895B2 (en) * 2009-01-20 2013-02-26 Spectro, Inc. Spectrometer flip top sample head
US9791386B2 (en) 2009-01-20 2017-10-17 Spectro Scientific, Inc. Integrated, portable sample analysis system and method
AU2010206709B2 (en) 2009-01-22 2013-01-24 Biopath Automation, L.L.C. Microtome sectionable biopsy support for orienting tissue samples
WO2011053631A1 (en) 2009-10-28 2011-05-05 Alentic Microscience Inc. Microscopy imaging
US20140152801A1 (en) 2009-10-28 2014-06-05 Alentic Microscience Inc. Detecting and Using Light Representative of a Sample
US9075225B2 (en) 2009-10-28 2015-07-07 Alentic Microscience Inc. Microscopy imaging
WO2011094659A2 (en) * 2010-02-01 2011-08-04 Clear-Cut Medical Ltd. Tumor margin assessment of ex -vivo sample
US9795340B2 (en) * 2010-12-13 2017-10-24 National Taiwan University Vacuum-pump sucker
US8661878B2 (en) 2011-01-18 2014-03-04 Spectro, Inc. Kinematic viscometer and method
CN202281862U (zh) * 2011-08-31 2012-06-20 清华大学 体视显微镜
ES2925001T3 (es) * 2012-01-16 2022-10-13 Mavig Gmbh Método para preparar una muestra de tejido
ES2878548T3 (es) * 2012-02-26 2021-11-19 Caliber Imaging & Diagnostics Inc Platina para muestras de tejido para un microscopio de seccionamiento óptico
WO2013142459A2 (en) * 2012-03-21 2013-09-26 Clear-Cut Medical Ltd. Mri system for margin assessment of ex-vivo sample
US9797816B2 (en) 2012-08-13 2017-10-24 Memorial Sloan-Kettering Cancer Center Devices applicable to tissue(s) which facilitates confocal microscopy, optical microscopy, spectroscopy and/or imaging
US8741232B2 (en) * 2012-09-05 2014-06-03 Faxitron Bioptics, Llc Specimen imaging device and methods for use thereof
US9677869B2 (en) 2012-12-05 2017-06-13 Perimeter Medical Imaging, Inc. System and method for generating a wide-field OCT image of a portion of a sample
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
US9518920B2 (en) * 2013-06-26 2016-12-13 Alentic Microscience Inc. Sample processing improvements for microscopy
US9885862B2 (en) * 2013-05-01 2018-02-06 Bio-Rad Laboratories, Inc. Adjustable digital microscope display
JP6446780B2 (ja) * 2013-12-20 2019-01-09 東洋紡株式会社 検鏡プレート、検鏡プレートの半製品および検鏡プレートの製造方法
US12620548B2 (en) 2014-01-27 2026-05-05 Mochii, Inc. Transmission electron microscopy
GB2523774B (en) * 2014-03-04 2019-07-17 Calamat Ltd Microscope slide
AU2015256153B2 (en) * 2014-05-05 2020-04-23 AURAD GmbH System and method for mapping the locations of captured confocal images of a lesion in skin tissue
WO2016001126A1 (en) 2014-06-30 2016-01-07 Koninklijke Philips N.V. Sample holder for biological samples
CN107110772B (zh) * 2014-11-25 2020-05-19 松下知识产权经营株式会社 电子标本保持部件、及其组装方法
KR101689879B1 (ko) 2015-08-31 2016-12-26 재단법인 의약바이오컨버젼스연구단 생체 내 유방조직 미세영상 획득을 위한 윈도우 장치 및 이를 이용한 영상 획득 방법
KR101743283B1 (ko) * 2015-08-31 2017-06-02 재단법인 의약바이오컨버젼스연구단 생체 내 폐조직 미세영상 획득을 위한 미세흡인 기반 폐 윈도우 장치 및 이를 이용한 영상 획득 방법
WO2017053825A1 (en) 2015-09-25 2017-03-30 The Regents Of The University Of Michigan Biopsy device for coherent raman imaging
US10514532B1 (en) 2015-09-27 2019-12-24 Caliber Imaging & Diagnostics, Inc. Confocal microscope having a positionable imaging head mounted on a boom stand
JP6550348B2 (ja) * 2016-04-07 2019-07-24 一般社団法人白亜会 生検材料デジタル画像化装置
EP3865927B1 (en) 2016-04-21 2023-08-02 President And Fellows Of Harvard College Tape for collecting tissue samples
BR112019009597B1 (pt) 2016-11-12 2023-11-28 Caliber Imaging & Diagnostics, Inc. Microscópio, e, método para formação de imagem de tecido
US11774361B2 (en) 2017-05-04 2023-10-03 The Regents Of The University Of California Waveguide-based side-illumination technique for muse microscopy and associated histology cassettes
DE102018210556A1 (de) * 2017-07-11 2019-01-17 Carl Zeiss Microscopy Gmbh Adapter zur Verwendung mit einem Probenhalter sowie Verfahren zum Anordnen einer Probe in einem Detektionsstrahlengang eines Mikroskops
EP3655748B1 (en) 2017-07-18 2023-08-09 Perimeter Medical Imaging, Inc. Sample container for stabilizing and aligning excised biological tissue samples for ex vivo analysis
JP7092294B2 (ja) * 2017-12-13 2022-06-28 学校法人東海大学 超薄膜から成る生体組織被覆用材料、及びそれで被覆された生体組織
CN112534259A (zh) * 2017-12-14 2021-03-19 Essenlix公司 监测毛发的装置，系统和方法
CN112136071B (zh) * 2018-02-26 2023-08-11 凯利博成像和诊断公司 用于对体外组织进行宏观和微观成像的系统和方法
US10527528B2 (en) * 2018-05-22 2020-01-07 Applikate Technologies Llc Tissue chamber
DE102018221670A1 (de) * 2018-12-13 2020-06-18 Karlsruher Institut für Technologie Vorrichtung und Verfahren zur optischen Charakterisierung oder Bearbeitung eines Objekts
KR20220050892A (ko) * 2019-07-17 2022-04-25 유이 라이프사이언시스 인코포레이티드 용량성 촉각 센서의 사용에 의해 조직 파라미터들을 측정하기 위한 시스템 및 방법
DE102019120201B3 (de) * 2019-07-25 2020-06-04 Leica Biosystems Nussloch Gmbh Anordnung mit Objektplatte und transparentem Markierungsrahmen
CN110646274B (zh) * 2019-09-18 2022-04-22 山东省立医院 一种一次性术中冰冻病理组织取材收集装置及其应用
US11498077B2 (en) * 2019-11-12 2022-11-15 Biopath Automation, Llc Sectionable cassette and embedding frame with connectors, and methods for preparing biopsy tissue samples
JP7365887B2 (ja) * 2019-12-17 2023-10-20 浜松ホトニクス株式会社 生体試料保持容器及び生体試料保持方法
JP2023517036A (ja) 2020-03-06 2023-04-21 アレンティック マイクロサイエンス インコーポレイテッド 携帯型撮像デバイス
CN120752091A (zh) * 2023-02-14 2025-10-03 艾普利凯特科技股份有限公司 组织腔室
DE102023208575A1 (de) 2023-09-06 2025-03-06 Robert Bosch Gesellschaft mit beschränkter Haftung Mikrofluidische Vorrichtung, Auswertevorrichtung, Verfahren zur Herstellung einer mikrofluidischen Vorrichtung sowie Steuergerät

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1002910A (en) * 1911-01-21 1911-09-12 Foote Mineral Co Display-mount.
US2942520A (en) * 1955-12-20 1960-06-28 George G Rose Tissue culture device
US3031924A (en) * 1959-03-12 1962-05-01 James C Lamal Observation slide
US3510194A (en) * 1965-08-09 1970-05-05 Robert F Connelly Particle count membrane filter mount
US3551023A (en) * 1969-01-17 1970-12-29 Ibm Pathology specimen processing method and article
US3556633A (en) * 1969-01-17 1971-01-19 Winifred Liu Mutschmann Specimen carrying slide with runoff trough
US3532412A (en) * 1969-01-17 1970-10-06 Ibm Package for and method of packaging pathology specimens
US3736042A (en) * 1971-05-05 1973-05-29 Clinical Sciences Inc Microscope slide assembly
US3879106A (en) * 1973-04-11 1975-04-22 Pelam Inc Microscope slide cover slip
US3990850A (en) * 1976-01-06 1976-11-09 Akzona Incorporated Diagnostic test card
DE2655041C2 (de) * 1976-12-04 1982-04-15 Fa. Carl Zeiss, 7920 Heidenheim Immersionsobjektiv zum Gebrauch mit mehreren optisch verschiedenen Immersionsmitteln
US4565783A (en) * 1981-01-27 1986-01-21 Minnesota Mining And Manufacturing Company Dry culture media
US4545831A (en) * 1982-09-13 1985-10-08 The Mount Sinai School Of Medicine Method for transferring a thin tissue section
SE455736B (sv) 1984-03-15 1988-08-01 Sarastro Ab Forfaringssett och anordning for mikrofotometrering och efterfoljande bildsammanstellning
US4752347A (en) 1986-10-03 1988-06-21 Rada David C Apparatus for preparing tissue sections
FR2626383B1 (fr) 1988-01-27 1991-10-25 Commissariat Energie Atomique Procede de microscopie optique confocale a balayage et en profondeur de champ etendue et dispositifs pour la mise en oeuvre du procede
US4974952A (en) 1988-03-31 1990-12-04 Focht Daniel C Live cell chamber for microscopes
US5002735A (en) * 1988-07-12 1991-03-26 Mark T. Alberhasky Tissue analysis device
DE02012428T1 (de) 1988-07-13 2005-12-15 Optiscan Pty. Ltd., Toorak Konfokales Rastermikroskop
JPH0641948B2 (ja) * 1988-09-21 1994-06-01 フクビ化学工業株式会社 観察用プレートおよびその製造方法
JPH0378720A (ja) 1989-08-22 1991-04-03 Nikon Corp 共焦点型レーザ走査顕微鏡
US5034613A (en) 1989-11-14 1991-07-23 Cornell Research Foundation, Inc. Two-photon laser microscopy
US5719700A (en) 1991-10-11 1998-02-17 L'oreal Apparatus for in vivo observation of the microscopic structure of the skin or of a similar tissue
US5889881A (en) 1992-10-14 1999-03-30 Oncometrics Imaging Corp. Method and apparatus for automatically detecting malignancy-associated changes
GB2273994A (en) 1992-12-18 1994-07-06 Morphometrix Inc Process microscopy system
US5364790A (en) * 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
US5383472A (en) * 1993-07-22 1995-01-24 Devlin; Mark T. Method and apparatus for handling of biopsy tissue specimen
PT720508E (pt) 1993-09-22 2000-09-29 Pierce Chemical Co Dispositivo para dialisar amostras
DE4423935C2 (de) * 1994-07-07 1998-02-05 Deutsche Forsch Luft Raumfahrt Küvette zur mikroskopischen oder makroskopischen Beobachtung einer biologischen Probe
WO1996021938A1 (en) 1995-01-13 1996-07-18 The General Hospital Corporation Video-rate confocal scanning laser microscope
US5880880A (en) 1995-01-13 1999-03-09 The General Hospital Corp. Three-dimensional scanning confocal laser microscope
US5788639A (en) 1995-07-13 1998-08-04 Lucid Technologies, Inc. Confocal imaging through thick dermal tissue
US5939251A (en) * 1996-07-12 1999-08-17 Hu; Min Apparatus and method for simplifying the processes in creating a sealed space on slides to conduct molecular biological reactions therein
US5870223A (en) * 1996-07-22 1999-02-09 Nikon Corporation Microscope system for liquid immersion observation
US6272235B1 (en) 1997-03-03 2001-08-07 Bacus Research Laboratories, Inc. Method and apparatus for creating a virtual microscope slide
US5836877A (en) * 1997-02-24 1998-11-17 Lucid Inc System for facilitating pathological examination of a lesion in tissue
US5812312A (en) * 1997-09-04 1998-09-22 Lorincz; Andrew Endre Microscope slide
US6048723A (en) * 1997-12-02 2000-04-11 Flexcell International Corporation Flexible bottom culture plate for applying mechanical load to cell cultures
US6358475B1 (en) * 1998-05-27 2002-03-19 Becton, Dickinson And Company Device for preparing thin liquid for microscopic analysis
WO2000049447A1 (en) 1999-02-17 2000-08-24 Lucid, Inc. Tissue specimen holder
EP1169630B1 (en) * 1999-02-17 2017-02-01 Lucid, Inc. Cassette for facilitating optical sectioning of a retained tissue specimen
US20040133112A1 (en) * 2002-03-08 2004-07-08 Milind Rajadhyaksha System and method for macroscopic and confocal imaging of tissue
GB0219642D0 (en) * 2002-08-23 2002-10-02 Gauthier Pierre Method and device for preparing tissues sections
US7864996B2 (en) * 2006-02-17 2011-01-04 Lucid, Inc. System for macroscopic and confocal imaging of tissue

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180119257A (ko) * 2017-04-25 2018-11-02 가톨릭대학교 산학협력단 의료용 검사 슬라이드 유닛
KR101940399B1 (ko) * 2017-04-25 2019-01-18 가톨릭대학교 산학협력단 의료용 검사 슬라이드 유닛

Also Published As

Publication number Publication date
AU3493800A (en) 2000-09-04
US9052523B2 (en) 2015-06-09
US20150277094A1 (en) 2015-10-01
EP1169630A4 (en) 2007-10-24
WO2000049392A1 (en) 2000-08-24
JP2002537573A (ja) 2002-11-05
US6411434B1 (en) 2002-06-25
US20020154399A1 (en) 2002-10-24
US8149506B2 (en) 2012-04-03
US20130182318A1 (en) 2013-07-18
EP1169630A1 (en) 2002-01-09
US9772486B2 (en) 2017-09-26
EP1169630B1 (en) 2017-02-01
WO2000049392A9 (en) 2002-06-20

Similar Documents

Publication Publication Date Title
EP1169630B1 (en) Cassette for facilitating optical sectioning of a retained tissue specimen
ES2399327T3 (es) Método para recolectar y manipular muestras de tejido para análisis de biopsia
EP3704528B1 (en) Confocal scanning imaging systems with micro optical element arrays and methods of specimen imaging
EP3414553B1 (en) Method and apparatus for imaging unsectioned tissue specimens
US8115918B2 (en) Imaging of surgical biopsies
US6330106B1 (en) Tissue specimen holder
US7227630B1 (en) Imaging of surgical biopsies
JP2002501419A (ja) 外科用ミクロトーム
EP2817609B1 (en) Tissue specimen stage for an optical sectioning microscope
US6413252B1 (en) Confocal microscope for facilitating cryosurgery of tissue
US20200257098A1 (en) Imaging systems with micro optical element arrays and methods of specimen imaging
CA3205038A1 (en) Point-of-care microscope for real-time acquisition of volumetric histological images in vivo
RU2220411C2 (ru) Способ изготовления гистотопографических препаратов пленочных тканей
JP2026023578A (ja) パラフィンブロック中の生体サンプルの位置情報取得装置および位置情報取得方法
Billings et al. The gross room/surgical cutup
CN118843785A (zh) 使用壳聚糖基多孔材料制备显微镜检用样品的方法
Gross Optimizing the Mohs Microscope

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070215

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070215

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100316

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100614

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20100706

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20100802

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20130806

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees