JP4551762B2 - 3,4−ジクロロ−n−(2−シアノフェニル)−5−イソチアゾールカルボキサミドの製造方法 - Google Patents
3,4−ジクロロ−n−(2−シアノフェニル)−5−イソチアゾールカルボキサミドの製造方法 Download PDFInfo
- Publication number
- JP4551762B2 JP4551762B2 JP2004516609A JP2004516609A JP4551762B2 JP 4551762 B2 JP4551762 B2 JP 4551762B2 JP 2004516609 A JP2004516609 A JP 2004516609A JP 2004516609 A JP2004516609 A JP 2004516609A JP 4551762 B2 JP4551762 B2 JP 4551762B2
- Authority
- JP
- Japan
- Prior art keywords
- dichloro
- isothiazolecarboxamide
- formula
- cyanophenyl
- dimethylformamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HQAVSSIUUHAAEJ-UHFFFAOYSA-N CC(C1)C=CC(C(N)=O)=C1N Chemical compound CC(C1)C=CC(C(N)=O)=C1N HQAVSSIUUHAAEJ-UHFFFAOYSA-N 0.000 description 1
- WLPCAERCXQSYLQ-UHFFFAOYSA-N N#Cc(cccc1)c1NC(c([s]nc1Cl)c1Cl)=O Chemical compound N#Cc(cccc1)c1NC(c([s]nc1Cl)c1Cl)=O WLPCAERCXQSYLQ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Description
a)式:
Claims (7)
- 第1及び第2ステップを実施するために使用される溶媒がジメチルホルムアミドである請求の範囲第1項に記載の方法。
- 第2ステップを実施するために脱水剤としてジメチルホルムアミドと塩化チオニル、オキシ塩化リン、ホスゲンまたはクロロメチレンジメチルアンモニウムクロリドとの混合物を使用する請求の範囲第1項に記載の方法。
- 第1ステップを0から160℃の温度で実施する請求の範囲第1項に記載の方法。
- 第2ステップを−20から+80℃の温度で実施する請求の範囲第1項に記載の方法。
- 反応の第1及び第2ステップをワンポット反応で実施する請求の範囲第1項に記載の方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10228732A DE10228732A1 (de) | 2002-06-27 | 2002-06-27 | Verfahren zur Herstellung von 3,4-Dichlor-N-(2-cyano-phenyl)-5-isothiazolcarboxamid |
PCT/EP2003/006360 WO2004002968A1 (de) | 2002-06-27 | 2003-06-17 | Verfahren zur herstellung von 3,4-dichlor-n-(2-cyano-phenyl)-5-isothiazolcarboxamid |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2005530847A JP2005530847A (ja) | 2005-10-13 |
JP2005530847A5 JP2005530847A5 (ja) | 2006-08-10 |
JP4551762B2 true JP4551762B2 (ja) | 2010-09-29 |
Family
ID=29723489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004516609A Expired - Lifetime JP4551762B2 (ja) | 2002-06-27 | 2003-06-17 | 3,4−ジクロロ−n−(2−シアノフェニル)−5−イソチアゾールカルボキサミドの製造方法 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1519926B1 (ja) |
JP (1) | JP4551762B2 (ja) |
KR (1) | KR101069222B1 (ja) |
CN (1) | CN1325483C (ja) |
AT (1) | ATE308530T1 (ja) |
AU (1) | AU2003238510A1 (ja) |
DE (2) | DE10228732A1 (ja) |
TW (1) | TWI266766B (ja) |
WO (1) | WO2004002968A1 (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005035617A1 (de) | 2005-07-29 | 2007-02-15 | Bayer Cropscience Ag | Verfahren zur Herstellung von 3,4-Dichlor-N-(2-cyano-phenyl)-5-isothiazolcarboxamid |
CN103483287B (zh) * | 2013-10-12 | 2015-07-08 | 南开大学 | 一类含3,4-二氯异噻唑的双酰胺类化合物及其制备方法和用途 |
DK3638653T3 (da) | 2017-06-14 | 2022-03-07 | Bayer Ag | Fremgangsmåde til fremstilling af 3,4-dichlor-n-(2-cyanophenyl)-5-isothiazolcarboxamid |
JP7495881B2 (ja) * | 2018-04-06 | 2024-06-05 | バイエル・アクチエンゲゼルシヤフト | 3,4-ジクロロ-n-(2-シアノフェニル)-5-イソチアゾールカルボキサミドの製造方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2115625B2 (de) * | 1971-03-31 | 1978-07-06 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von N-o-Cyanophenyl-N', N'-disubstituierten Formamidinen und deren Salzen |
DE2115624A1 (de) * | 1971-03-31 | 1972-10-12 | Badische Anilin & Soda Fabrik AG, 6700 Ludwigshafen | Verfahren zur Herstellung von o Amino benzonitrilen |
DE19750012A1 (de) * | 1997-11-12 | 1999-05-20 | Bayer Ag | Isothiazolcarbonsäureamide |
-
2002
- 2002-06-27 DE DE10228732A patent/DE10228732A1/de not_active Withdrawn
-
2003
- 2003-06-17 WO PCT/EP2003/006360 patent/WO2004002968A1/de active IP Right Grant
- 2003-06-17 AT AT03732578T patent/ATE308530T1/de not_active IP Right Cessation
- 2003-06-17 DE DE50301572T patent/DE50301572D1/de not_active Expired - Lifetime
- 2003-06-17 AU AU2003238510A patent/AU2003238510A1/en not_active Abandoned
- 2003-06-17 EP EP03732578A patent/EP1519926B1/de not_active Expired - Lifetime
- 2003-06-17 JP JP2004516609A patent/JP4551762B2/ja not_active Expired - Lifetime
- 2003-06-17 CN CNB038203294A patent/CN1325483C/zh not_active Expired - Lifetime
- 2003-06-17 KR KR1020047021038A patent/KR101069222B1/ko active IP Right Grant
- 2003-06-26 TW TW092117350A patent/TWI266766B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TWI266766B (en) | 2006-11-21 |
TW200409762A (en) | 2004-06-16 |
ATE308530T1 (de) | 2005-11-15 |
AU2003238510A1 (en) | 2004-01-19 |
KR101069222B1 (ko) | 2011-09-30 |
EP1519926A1 (de) | 2005-04-06 |
KR20050008853A (ko) | 2005-01-21 |
EP1519926B1 (de) | 2005-11-02 |
DE10228732A1 (de) | 2004-01-15 |
CN1325483C (zh) | 2007-07-11 |
WO2004002968A1 (de) | 2004-01-08 |
JP2005530847A (ja) | 2005-10-13 |
CN1678595A (zh) | 2005-10-05 |
DE50301572D1 (de) | 2005-12-08 |
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