JP4549862B2 - クロマトグラフィーにおける移動相改質剤としてのアミンまたはアミノ酸の使用 - Google Patents

クロマトグラフィーにおける移動相改質剤としてのアミンまたはアミノ酸の使用 Download PDF

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Publication number
JP4549862B2
JP4549862B2 JP2004550127A JP2004550127A JP4549862B2 JP 4549862 B2 JP4549862 B2 JP 4549862B2 JP 2004550127 A JP2004550127 A JP 2004550127A JP 2004550127 A JP2004550127 A JP 2004550127A JP 4549862 B2 JP4549862 B2 JP 4549862B2
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Japan
Prior art keywords
mobile phase
amino acid
proline
pneumocandin
amino acids
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Expired - Fee Related
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JP2004550127A
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English (en)
Japanese (ja)
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JP2006504786A5 (https=
JP2006504786A (ja
Inventor
ゴクレン，ケント・イー
ンテイ−ギヤバー，ジヨセフ
アニータ，フイロツツ・デイ
ダールグレン，メアリー・エレン
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Merck and Co Inc
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Merck and Co Inc
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/284—Porous sorbents based on alumina
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/166—Fluid composition conditioning, e.g. gradient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B01D15/426—Specific type of solvent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/283—Porous sorbents based on silica
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
JP2004550127A 2002-10-30 2003-10-24 クロマトグラフィーにおける移動相改質剤としてのアミンまたはアミノ酸の使用 Expired - Fee Related JP4549862B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42235602P 2002-10-30 2002-10-30
PCT/US2003/033978 WO2004042350A2 (en) 2002-10-30 2003-10-24 Using amines or amino acids as mobile phase modifiers in chromatography

Publications (3)

Publication Number Publication Date
JP2006504786A JP2006504786A (ja) 2006-02-09
JP2006504786A5 JP2006504786A5 (https=) 2010-05-13
JP4549862B2 true JP4549862B2 (ja) 2010-09-22

Family

ID=32312493

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004550127A Expired - Fee Related JP4549862B2 (ja) 2002-10-30 2003-10-24 クロマトグラフィーにおける移動相改質剤としてのアミンまたはアミノ酸の使用

Country Status (12)

Country Link
US (1) US7241866B2 (https=)
EP (1) EP1558354B1 (https=)
JP (1) JP4549862B2 (https=)
AT (1) ATE457798T1 (https=)
AU (1) AU2003284163A1 (https=)
CY (1) CY1110296T1 (https=)
DE (1) DE60331338D1 (https=)
DK (1) DK1558354T3 (https=)
ES (1) ES2342772T3 (https=)
PT (1) PT1558354E (https=)
SI (1) SI1558354T1 (https=)
WO (1) WO2004042350A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPS264302A0 (en) * 2002-05-29 2002-06-20 Neopraxis Pty Ltd Implantable bladder sensor
CN103936837B (zh) * 2014-02-14 2016-05-25 博瑞生物医药泰兴市有限公司 一种提纯纽莫康定b0的方法
US10383550B2 (en) * 2014-07-17 2019-08-20 Elwha Llc Monitoring body movement or condition according to motion regimen with conformal electronics
CN105001305A (zh) * 2015-04-29 2015-10-28 利穗科技(苏州)有限公司 利用层析技术提取高纯度达托霉素的方法
CN108250274A (zh) * 2016-12-28 2018-07-06 浙江华谱新创科技有限公司 米卡芬净高效分离纯化方法
IL294319A (en) * 2020-01-08 2022-08-01 Regeneron Pharma Using amino acids to improve signals in mass spectrometry tests
CN111925421B (zh) * 2020-07-02 2022-05-10 北大方正集团有限公司 一种从发酵液中提取纽莫康定b0的方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812442A (en) 1984-05-29 1989-03-14 Merck & Co., Inc. Tripeptide renin inhibitors
IT1190433B (it) 1985-12-11 1988-02-16 Prodotti Antibiotici Spa Peptidi correlati al lisozima
US5202309A (en) 1989-06-30 1993-04-13 Merck & Co., Inc. Antibiotic cyclopeptide fermentation product
US5194377A (en) 1989-06-30 1993-03-16 Merck & Co., Inc. Antibiotic agent
GB9508195D0 (en) 1995-04-20 1995-06-07 Univ British Columbia Novel biologically active compounds and compositions,their use and derivation
EP0975560A4 (en) * 1997-03-18 2004-10-06 Chiral Technologies Inc CHIRAL SEPARATION OF AMINO ACIDS
JP3780638B2 (ja) * 1997-06-27 2006-05-31 東ソー株式会社 分離法及びこれを用いた装置

Also Published As

Publication number Publication date
ATE457798T1 (de) 2010-03-15
WO2004042350A2 (en) 2004-05-21
DK1558354T3 (da) 2010-05-25
EP1558354A2 (en) 2005-08-03
EP1558354B1 (en) 2010-02-17
SI1558354T1 (sl) 2010-05-31
US7241866B2 (en) 2007-07-10
PT1558354E (pt) 2010-04-20
JP2006504786A (ja) 2006-02-09
CY1110296T1 (el) 2015-01-14
AU2003284163A8 (en) 2004-06-07
EP1558354A4 (en) 2008-07-02
WO2004042350A3 (en) 2004-07-15
AU2003284163A1 (en) 2004-06-07
ES2342772T3 (es) 2010-07-14
DE60331338D1 (de) 2010-04-01
US20060014933A1 (en) 2006-01-19

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