DK1558354T3 - Anvendelse af aminer, aminosyrer eller aminosyreestere som mobilfasemodifikatorer i kromatografi - Google Patents

Anvendelse af aminer, aminosyrer eller aminosyreestere som mobilfasemodifikatorer i kromatografi

Info

Publication number
DK1558354T3
DK1558354T3 DK03776553.4T DK03776553T DK1558354T3 DK 1558354 T3 DK1558354 T3 DK 1558354T3 DK 03776553 T DK03776553 T DK 03776553T DK 1558354 T3 DK1558354 T3 DK 1558354T3
Authority
DK
Denmark
Prior art keywords
amino acid
chromatography
amines
acid esters
mobile phase
Prior art date
Application number
DK03776553.4T
Other languages
Danish (da)
English (en)
Inventor
Kent E Goklen
Joseph Nti-Gyabaah
Firoz D Antia
Mary Ellen Dahlgren
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK1558354T3 publication Critical patent/DK1558354T3/da

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • B01J20/284Porous sorbents based on alumina
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/166Fluid composition conditioning, e.g. gradient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424Elution mode
    • B01D15/426Specific type of solvent
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • B01J20/283Porous sorbents based on silica
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/16Oxytocins; Vasopressins; Related peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/18Kallidins; Bradykinins; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK03776553.4T 2002-10-30 2003-10-24 Anvendelse af aminer, aminosyrer eller aminosyreestere som mobilfasemodifikatorer i kromatografi DK1558354T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42235602P 2002-10-30 2002-10-30
PCT/US2003/033978 WO2004042350A2 (en) 2002-10-30 2003-10-24 Using amines or amino acids as mobile phase modifiers in chromatography

Publications (1)

Publication Number Publication Date
DK1558354T3 true DK1558354T3 (da) 2010-05-25

Family

ID=32312493

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03776553.4T DK1558354T3 (da) 2002-10-30 2003-10-24 Anvendelse af aminer, aminosyrer eller aminosyreestere som mobilfasemodifikatorer i kromatografi

Country Status (12)

Country Link
US (1) US7241866B2 (https=)
EP (1) EP1558354B1 (https=)
JP (1) JP4549862B2 (https=)
AT (1) ATE457798T1 (https=)
AU (1) AU2003284163A1 (https=)
CY (1) CY1110296T1 (https=)
DE (1) DE60331338D1 (https=)
DK (1) DK1558354T3 (https=)
ES (1) ES2342772T3 (https=)
PT (1) PT1558354E (https=)
SI (1) SI1558354T1 (https=)
WO (1) WO2004042350A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPS264302A0 (en) * 2002-05-29 2002-06-20 Neopraxis Pty Ltd Implantable bladder sensor
CN103936837B (zh) * 2014-02-14 2016-05-25 博瑞生物医药泰兴市有限公司 一种提纯纽莫康定b0的方法
US10383550B2 (en) * 2014-07-17 2019-08-20 Elwha Llc Monitoring body movement or condition according to motion regimen with conformal electronics
CN105001305A (zh) * 2015-04-29 2015-10-28 利穗科技(苏州)有限公司 利用层析技术提取高纯度达托霉素的方法
CN108250274A (zh) * 2016-12-28 2018-07-06 浙江华谱新创科技有限公司 米卡芬净高效分离纯化方法
IL294319A (en) * 2020-01-08 2022-08-01 Regeneron Pharma Using amino acids to improve signals in mass spectrometry tests
CN111925421B (zh) * 2020-07-02 2022-05-10 北大方正集团有限公司 一种从发酵液中提取纽莫康定b0的方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812442A (en) 1984-05-29 1989-03-14 Merck & Co., Inc. Tripeptide renin inhibitors
IT1190433B (it) 1985-12-11 1988-02-16 Prodotti Antibiotici Spa Peptidi correlati al lisozima
US5202309A (en) 1989-06-30 1993-04-13 Merck & Co., Inc. Antibiotic cyclopeptide fermentation product
US5194377A (en) 1989-06-30 1993-03-16 Merck & Co., Inc. Antibiotic agent
GB9508195D0 (en) 1995-04-20 1995-06-07 Univ British Columbia Novel biologically active compounds and compositions,their use and derivation
EP0975560A4 (en) * 1997-03-18 2004-10-06 Chiral Technologies Inc CHIRAL SEPARATION OF AMINO ACIDS
JP3780638B2 (ja) * 1997-06-27 2006-05-31 東ソー株式会社 分離法及びこれを用いた装置

Also Published As

Publication number Publication date
ATE457798T1 (de) 2010-03-15
JP4549862B2 (ja) 2010-09-22
WO2004042350A2 (en) 2004-05-21
EP1558354A2 (en) 2005-08-03
EP1558354B1 (en) 2010-02-17
SI1558354T1 (sl) 2010-05-31
US7241866B2 (en) 2007-07-10
PT1558354E (pt) 2010-04-20
JP2006504786A (ja) 2006-02-09
CY1110296T1 (el) 2015-01-14
AU2003284163A8 (en) 2004-06-07
EP1558354A4 (en) 2008-07-02
WO2004042350A3 (en) 2004-07-15
AU2003284163A1 (en) 2004-06-07
ES2342772T3 (es) 2010-07-14
DE60331338D1 (de) 2010-04-01
US20060014933A1 (en) 2006-01-19

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