CY1110296T1 - Χρηση αμινων ή αμινοξεων ως τροποποιητες κινητης φασης στη χρωματογραφια - Google Patents
Χρηση αμινων ή αμινοξεων ως τροποποιητες κινητης φασης στη χρωματογραφιαInfo
- Publication number
- CY1110296T1 CY1110296T1 CY20101100422T CY101100422T CY1110296T1 CY 1110296 T1 CY1110296 T1 CY 1110296T1 CY 20101100422 T CY20101100422 T CY 20101100422T CY 101100422 T CY101100422 T CY 101100422T CY 1110296 T1 CY1110296 T1 CY 1110296T1
- Authority
- CY
- Cyprus
- Prior art keywords
- chromatography
- aminoids
- amines
- mobile phase
- phase modifiers
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/282—Porous sorbents
- B01J20/284—Porous sorbents based on alumina
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
- B01D15/166—Fluid composition conditioning, e.g. gradient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/424—Elution mode
- B01D15/426—Specific type of solvent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/282—Porous sorbents
- B01J20/283—Porous sorbents based on silica
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/18—Kallidins; Bradykinins; Related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με τη χρήση τροποποιητών κινητής φάσης αμίνη, αμινοξύ ή αμινοξικό εστέρα, σε χρωματογραφία κανονικής φάσης για βελτίωση της ανάλυσης ή/και της παραγωγικότητας στον καθαρισμό πεπτιδίου και λιποπεπτιδίου. Αυτή η μέθοδος χρωματογραφίας μπορεί να χρησιμοποιηθεί για καθαρισμό είτε αναλυτικής είτε παρασκευαστικής κλίμακας.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42235602P | 2002-10-30 | 2002-10-30 | |
EP03776553A EP1558354B1 (en) | 2002-10-30 | 2003-10-24 | Using amines, amino acids or amino acid esters as mobile phase modifiers in chromatography |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1110296T1 true CY1110296T1 (el) | 2015-01-14 |
Family
ID=32312493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101100422T CY1110296T1 (el) | 2002-10-30 | 2010-05-14 | Χρηση αμινων ή αμινοξεων ως τροποποιητες κινητης φασης στη χρωματογραφια |
Country Status (12)
Country | Link |
---|---|
US (1) | US7241866B2 (el) |
EP (1) | EP1558354B1 (el) |
JP (1) | JP4549862B2 (el) |
AT (1) | ATE457798T1 (el) |
AU (1) | AU2003284163A1 (el) |
CY (1) | CY1110296T1 (el) |
DE (1) | DE60331338D1 (el) |
DK (1) | DK1558354T3 (el) |
ES (1) | ES2342772T3 (el) |
PT (1) | PT1558354E (el) |
SI (1) | SI1558354T1 (el) |
WO (1) | WO2004042350A2 (el) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPS264302A0 (en) * | 2002-05-29 | 2002-06-20 | Neopraxis Pty Ltd | Implantable bladder sensor |
CN103936837B (zh) * | 2014-02-14 | 2016-05-25 | 博瑞生物医药泰兴市有限公司 | 一种提纯纽莫康定b0的方法 |
US10383550B2 (en) * | 2014-07-17 | 2019-08-20 | Elwha Llc | Monitoring body movement or condition according to motion regimen with conformal electronics |
CN105001305A (zh) * | 2015-04-29 | 2015-10-28 | 利穗科技(苏州)有限公司 | 利用层析技术提取高纯度达托霉素的方法 |
CN108250274A (zh) * | 2016-12-28 | 2018-07-06 | 浙江华谱新创科技有限公司 | 米卡芬净高效分离纯化方法 |
JP2023509759A (ja) * | 2020-01-08 | 2023-03-09 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 質量スペクトル分析においてシグナルを増強するためのアミノ酸の使用 |
CN111925421B (zh) * | 2020-07-02 | 2022-05-10 | 北大方正集团有限公司 | 一种从发酵液中提取纽莫康定b0的方法与应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4812442A (en) * | 1984-05-29 | 1989-03-14 | Merck & Co., Inc. | Tripeptide renin inhibitors |
IT1190433B (it) * | 1985-12-11 | 1988-02-16 | Prodotti Antibiotici Spa | Peptidi correlati al lisozima |
US5202309A (en) * | 1989-06-30 | 1993-04-13 | Merck & Co., Inc. | Antibiotic cyclopeptide fermentation product |
US5194377A (en) * | 1989-06-30 | 1993-03-16 | Merck & Co., Inc. | Antibiotic agent |
GB9508195D0 (en) * | 1995-04-20 | 1995-06-07 | Univ British Columbia | Novel biologically active compounds and compositions,their use and derivation |
US6130353A (en) * | 1997-03-18 | 2000-10-10 | Chiral Technologies, Inc. | Chiral separations of amino acids |
JP3780638B2 (ja) * | 1997-06-27 | 2006-05-31 | 東ソー株式会社 | 分離法及びこれを用いた装置 |
-
2003
- 2003-10-24 DE DE60331338T patent/DE60331338D1/de not_active Expired - Lifetime
- 2003-10-24 JP JP2004550127A patent/JP4549862B2/ja not_active Expired - Fee Related
- 2003-10-24 AU AU2003284163A patent/AU2003284163A1/en not_active Abandoned
- 2003-10-24 ES ES03776553T patent/ES2342772T3/es not_active Expired - Lifetime
- 2003-10-24 US US10/526,301 patent/US7241866B2/en not_active Expired - Fee Related
- 2003-10-24 EP EP03776553A patent/EP1558354B1/en not_active Expired - Lifetime
- 2003-10-24 DK DK03776553.4T patent/DK1558354T3/da active
- 2003-10-24 SI SI200331785T patent/SI1558354T1/sl unknown
- 2003-10-24 AT AT03776553T patent/ATE457798T1/de active
- 2003-10-24 WO PCT/US2003/033978 patent/WO2004042350A2/en active Application Filing
- 2003-10-24 PT PT03776553T patent/PT1558354E/pt unknown
-
2010
- 2010-05-14 CY CY20101100422T patent/CY1110296T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1558354A2 (en) | 2005-08-03 |
EP1558354B1 (en) | 2010-02-17 |
WO2004042350A3 (en) | 2004-07-15 |
US20060014933A1 (en) | 2006-01-19 |
EP1558354A4 (en) | 2008-07-02 |
ES2342772T3 (es) | 2010-07-14 |
US7241866B2 (en) | 2007-07-10 |
ATE457798T1 (de) | 2010-03-15 |
WO2004042350A2 (en) | 2004-05-21 |
PT1558354E (pt) | 2010-04-20 |
JP2006504786A (ja) | 2006-02-09 |
AU2003284163A1 (en) | 2004-06-07 |
AU2003284163A8 (en) | 2004-06-07 |
SI1558354T1 (sl) | 2010-05-31 |
JP4549862B2 (ja) | 2010-09-22 |
DE60331338D1 (de) | 2010-04-01 |
DK1558354T3 (da) | 2010-05-25 |
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