JP4492849B2 - 転写および炎症性疾患および感染症に対する感受性に影響するインターロイキン−1遺伝子座の機能的多型 - Google Patents
転写および炎症性疾患および感染症に対する感受性に影響するインターロイキン−1遺伝子座の機能的多型 Download PDFInfo
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- JP4492849B2 JP4492849B2 JP2003545801A JP2003545801A JP4492849B2 JP 4492849 B2 JP4492849 B2 JP 4492849B2 JP 2003545801 A JP2003545801 A JP 2003545801A JP 2003545801 A JP2003545801 A JP 2003545801A JP 4492849 B2 JP4492849 B2 JP 4492849B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/204—Modifications characterised by specific length of the oligonucleotides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33168101P | 2001-11-19 | 2001-11-19 | |
| US38602002P | 2002-06-05 | 2002-06-05 | |
| PCT/US2002/037222 WO2003044176A2 (en) | 2001-11-19 | 2002-11-19 | Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009260743A Division JP2010029220A (ja) | 2001-11-19 | 2009-11-16 | 転写および炎症性疾患および感染症に対する感受性に影響するインターロイキン−1遺伝子座の機能的多型 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005509432A JP2005509432A (ja) | 2005-04-14 |
| JP2005509432A5 JP2005509432A5 (enExample) | 2006-01-12 |
| JP4492849B2 true JP4492849B2 (ja) | 2010-06-30 |
Family
ID=26987865
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003545801A Expired - Lifetime JP4492849B2 (ja) | 2001-11-19 | 2002-11-19 | 転写および炎症性疾患および感染症に対する感受性に影響するインターロイキン−1遺伝子座の機能的多型 |
| JP2009260743A Pending JP2010029220A (ja) | 2001-11-19 | 2009-11-16 | 転写および炎症性疾患および感染症に対する感受性に影響するインターロイキン−1遺伝子座の機能的多型 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009260743A Pending JP2010029220A (ja) | 2001-11-19 | 2009-11-16 | 転写および炎症性疾患および感染症に対する感受性に影響するインターロイキン−1遺伝子座の機能的多型 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20030235890A1 (enExample) |
| EP (1) | EP1463745A4 (enExample) |
| JP (2) | JP4492849B2 (enExample) |
| KR (2) | KR101059898B1 (enExample) |
| CN (2) | CN101955943A (enExample) |
| AU (1) | AU2002359431A1 (enExample) |
| CA (1) | CA2467717A1 (enExample) |
| WO (1) | WO2003044176A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7820383B2 (en) * | 1997-03-10 | 2010-10-26 | Interleukin Genetics, Inc. | Method for diagnosing myocardial infarction |
| GB9711040D0 (en) * | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| CA2378221A1 (en) * | 1999-06-30 | 2001-01-04 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for diseases associated with an il-1 inflammatory haplotype |
| US20080311581A1 (en) * | 2001-11-19 | 2008-12-18 | David Wyllie | Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases |
| US20070264645A1 (en) * | 2002-01-25 | 2007-11-15 | Kenneth Kornman | IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
| DE60319719T2 (de) * | 2002-09-30 | 2009-03-12 | Novartis Ag | Verfahren zur voraussage der erhöhung von cholesterin während einer immunosuppresiven therapie |
| US20050175721A1 (en) * | 2004-02-06 | 2005-08-11 | Brovelli Ernesto A. | Method of augmenting the immune-modulatory activity of standardized Echinacea preparations |
| AU2005216298B2 (en) * | 2004-02-26 | 2010-09-02 | Baylor Research Institute | Compositions and methods for the systemic treatment of arthritis |
| ATE490341T1 (de) * | 2004-05-03 | 2010-12-15 | Interleukin Genetics Inc | Diagnostika und therapeutika für mit einem entzündlichen il-1-haplotyp assoziierte krankheiten |
| WO2006022277A1 (ja) * | 2004-08-24 | 2006-03-02 | Fujifilm Corporation | 表面プラズモン共鳴分析における解離定数の算出方法 |
| JP2006262826A (ja) * | 2005-03-25 | 2006-10-05 | Institute Of Physical & Chemical Research | インターロイキン−1受容体2遺伝子の多型に基づく炎症性疾患の検査法 |
| EP1951903A2 (en) * | 2005-10-25 | 2008-08-06 | Interleukin Genetics, Inc. | The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
| JP4870976B2 (ja) * | 2005-11-10 | 2012-02-08 | 株式会社Dnaチップ研究所 | 全血を用いた自己免疫疾患の検査方法 |
| US8101360B2 (en) * | 2006-11-15 | 2012-01-24 | Interleukin Genetics, Inc. | IL-1 gene cluster, insulin resistance and coronary artery disease associated polymorphisms and haplotypes and methods of using same |
| CA2705142A1 (en) * | 2007-11-08 | 2009-05-14 | Interleukin Genetics, Inc. | Diagnostics for aging-related dermatologic disorders |
| EP3402900A1 (en) | 2016-01-12 | 2018-11-21 | Interleukin Genetics, Inc. | Methods for predicting response to treatment |
| KR102543907B1 (ko) * | 2016-06-17 | 2023-06-15 | 서울대학교산학협력단 | 치주질환 위험도 평가용 유전자 마커 |
| US10329620B2 (en) | 2017-01-12 | 2019-06-25 | Cardioforecast Ltd. | Methods and kits for treating cardiovascular disease |
| JP7097855B2 (ja) * | 2019-04-24 | 2022-07-08 | ジェネシスヘルスケア株式会社 | 歯周病のリスクを判定する方法 |
| EP3980561A1 (en) | 2019-06-06 | 2022-04-13 | Sitokine Limited | Compositions and methods for treating lung, colorectal and breast cancer |
| WO2021028469A1 (en) | 2019-08-12 | 2021-02-18 | Sitokine Limited | Compositions and methods for treating cytokine release syndrome and neurotoxicity |
| WO2021205013A1 (en) | 2020-04-09 | 2021-10-14 | Sitokine Limited | Compositions and methods for treating covid-19 |
| WO2022040090A1 (en) * | 2020-08-17 | 2022-02-24 | The Regents Of The University Of California | Application of microbial glycosidase as an anti-viral therapeutic, prognostic, and diagnostic |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8311018D0 (en) * | 1983-04-22 | 1983-05-25 | Amersham Int Plc | Detecting mutations in dna |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4833080A (en) * | 1985-12-12 | 1989-05-23 | President And Fellows Of Harvard College | Regulation of eucaryotic gene expression |
| US4998617A (en) * | 1986-09-15 | 1991-03-12 | Laura Lupton Inc | Facial cosmetic liquid make up kit |
| US4968607A (en) * | 1987-11-25 | 1990-11-06 | Immunex Corporation | Interleukin-1 receptors |
| US5459039A (en) * | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
| US5593826A (en) * | 1993-03-22 | 1997-01-14 | Perkin-Elmer Corporation, Applied Biosystems, Inc. | Enzymatic ligation of 3'amino-substituted oligonucleotides |
| US5747498A (en) * | 1996-05-28 | 1998-05-05 | Pfizer Inc. | Alkynyl and azido-substituted 4-anilinoquinazolines |
| US5686246A (en) * | 1995-08-03 | 1997-11-11 | Kornman; Kenneth S. | Detecting genetic predisposition to periodontal disease |
| GB9603095D0 (en) * | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
| US5698399A (en) * | 1996-04-05 | 1997-12-16 | Duff; Gordon W. | Detecting genetic predisposition for osteoporosis |
| GB9621129D0 (en) * | 1996-10-10 | 1996-11-27 | Duff Gordon W | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| US6210877B1 (en) * | 1997-03-10 | 2001-04-03 | Interleukin Genetics, Inc. | Prediction of coronary artery disease |
| US6524795B1 (en) | 1997-03-10 | 2003-02-25 | Interleukin Genetics, Inc. | Diagnostics for cardiovascular disorders |
| GB9723553D0 (en) * | 1997-11-07 | 1998-01-07 | Duff Gordon W | Prediction of the risk of chronic obstructive airway disease |
| GB9711040D0 (en) * | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| US6437216B1 (en) * | 1997-11-13 | 2002-08-20 | Interleukin Genetics Inc. | Transgenic models of inflammatory disease |
| US6251598B1 (en) * | 1998-10-30 | 2001-06-26 | Interleukin Genetics, Inc. | Methods for diagnosing sepsis |
| CA2378221A1 (en) | 1999-06-30 | 2001-01-04 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for diseases associated with an il-1 inflammatory haplotype |
| BR0014133A (pt) * | 1999-09-21 | 2002-06-11 | Astrazeneca Ab | Uso de um composto, composto, métodos de preparação de um composto, e para inibir aurora 2 quinase em um animal de sangue quente, e, composição farmacêutica |
| US6656946B2 (en) * | 2000-08-26 | 2003-12-02 | Boehringer Ingelheim Pharma Kg | Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases |
| US6617329B2 (en) * | 2000-08-26 | 2003-09-09 | Boehringer Ingelheim Pharma Kg | Aminoquinazolines and their use as medicaments |
| WO2002103031A2 (en) | 2001-06-15 | 2002-12-27 | Interleukin Genetics, Inc. | Methods for detecting and treating the early onset of aging-related conditions |
| TW200813014A (en) * | 2002-03-28 | 2008-03-16 | Astrazeneca Ab | Quinazoline derivatives |
| US6924285B2 (en) * | 2002-03-30 | 2005-08-02 | Boehringer Ingelheim Pharma Gmbh & Co. | Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them |
| US8071304B2 (en) * | 2003-04-05 | 2011-12-06 | The Johns Hopkins University | Methods for detecting a polymorphism in the NFKB1 gene promoter |
-
2002
- 2002-11-19 US US10/300,011 patent/US20030235890A1/en not_active Abandoned
- 2002-11-19 WO PCT/US2002/037222 patent/WO2003044176A2/en not_active Ceased
- 2002-11-19 CA CA002467717A patent/CA2467717A1/en not_active Abandoned
- 2002-11-19 EP EP02793968A patent/EP1463745A4/en not_active Withdrawn
- 2002-11-19 CN CN201010156318.0A patent/CN101955943A/zh active Pending
- 2002-11-19 CN CN02827282.XA patent/CN1753903B/zh not_active Expired - Fee Related
- 2002-11-19 JP JP2003545801A patent/JP4492849B2/ja not_active Expired - Lifetime
- 2002-11-19 KR KR1020107016833A patent/KR101059898B1/ko not_active Expired - Fee Related
- 2002-11-19 KR KR1020047007653A patent/KR101019131B1/ko not_active Expired - Fee Related
- 2002-11-19 AU AU2002359431A patent/AU2002359431A1/en not_active Abandoned
-
2008
- 2008-03-13 US US12/048,077 patent/US20100279280A1/en not_active Abandoned
-
2009
- 2009-11-16 JP JP2009260743A patent/JP2010029220A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005509432A (ja) | 2005-04-14 |
| CN101955943A (zh) | 2011-01-26 |
| CN1753903B (zh) | 2010-05-12 |
| AU2002359431A1 (en) | 2003-06-10 |
| EP1463745A4 (en) | 2007-11-07 |
| JP2010029220A (ja) | 2010-02-12 |
| EP1463745A2 (en) | 2004-10-06 |
| US20030235890A1 (en) | 2003-12-25 |
| WO2003044176A2 (en) | 2003-05-30 |
| AU2002359431A8 (en) | 2003-06-10 |
| CA2467717A1 (en) | 2003-05-30 |
| WO2003044176A8 (en) | 2003-08-21 |
| KR20040066832A (ko) | 2004-07-27 |
| WO2003044176A9 (en) | 2003-10-16 |
| KR20100095652A (ko) | 2010-08-31 |
| US20100279280A1 (en) | 2010-11-04 |
| CN1753903A (zh) | 2006-03-29 |
| WO2003044176A3 (en) | 2004-07-29 |
| KR101019131B1 (ko) | 2011-03-07 |
| KR101059898B1 (ko) | 2011-08-29 |
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