JP4476807B2 - ポリ(カリウムおよびスチレンスルホン酸ナトリウム)、その製造およびその使用 - Google Patents
ポリ(カリウムおよびスチレンスルホン酸ナトリウム)、その製造およびその使用 Download PDFInfo
- Publication number
- JP4476807B2 JP4476807B2 JP2004523573A JP2004523573A JP4476807B2 JP 4476807 B2 JP4476807 B2 JP 4476807B2 JP 2004523573 A JP2004523573 A JP 2004523573A JP 2004523573 A JP2004523573 A JP 2004523573A JP 4476807 B2 JP4476807 B2 JP 4476807B2
- Authority
- JP
- Japan
- Prior art keywords
- potassium
- sodium
- copolymer
- solution
- polystyrene sulfonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F12/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
- C08F12/02—Monomers containing only one unsaturated aliphatic radical
- C08F12/04—Monomers containing only one unsaturated aliphatic radical containing one ring
- C08F12/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by hetero atoms or groups containing heteroatoms
- C08F12/30—Sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/795—Polymers containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/44—Preparation of metal salts or ammonium salts
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L25/00—Compositions of, homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring; Compositions of derivatives of such polymers
- C08L25/18—Homopolymers or copolymers of aromatic monomers containing elements other than carbon and hydrogen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39786802P | 2002-07-22 | 2002-07-22 | |
| PCT/US2003/022514 WO2004009100A1 (en) | 2002-07-22 | 2003-07-18 | Poly (potassium and sodium styrene sulfonate), its manufacture and its uses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006502249A JP2006502249A (ja) | 2006-01-19 |
| JP2006502249A5 JP2006502249A5 (enExample) | 2006-07-13 |
| JP4476807B2 true JP4476807B2 (ja) | 2010-06-09 |
Family
ID=30771134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004523573A Expired - Lifetime JP4476807B2 (ja) | 2002-07-22 | 2003-07-18 | ポリ(カリウムおよびスチレンスルホン酸ナトリウム)、その製造およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US20050214246A1 (enExample) |
| EP (1) | EP1542706A1 (enExample) |
| JP (1) | JP4476807B2 (enExample) |
| KR (1) | KR20050030208A (enExample) |
| CN (3) | CN101319023A (enExample) |
| AU (1) | AU2003254007B2 (enExample) |
| BR (1) | BR0312884A (enExample) |
| CA (1) | CA2492211A1 (enExample) |
| MX (1) | MXPA05000687A (enExample) |
| NZ (1) | NZ537594A (enExample) |
| WO (1) | WO2004009100A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7951853B2 (en) * | 2002-05-02 | 2011-05-31 | Smart Anti-Microbial Solutions, Llc | Polymer-based antimicrobial agents, methods of making said agents, and products incorporating said agents |
| CA2492211A1 (en) * | 2002-07-22 | 2004-01-29 | Genzyme Corporation | Poly(potassium and sodium styrene sulfonate), its manufacture and its uses |
| CA2470090A1 (fr) * | 2004-06-18 | 2005-12-18 | Bio-K Plus International Inc. | Bacteries lactiques et leurs usages dans la prevention de diarrhee associee aux antibiotiques |
| US20060078534A1 (en) * | 2004-10-13 | 2006-04-13 | Dominique Charmot | Toxin binding compositions |
| JP2008515996A (ja) * | 2004-10-13 | 2008-05-15 | イリプサ, インコーポレイテッド | 毒素結合性オリゴ糖および重合体粒子を含有する医薬組成物 |
| US20120135060A1 (en) * | 2005-11-02 | 2012-05-31 | Shmuel Bukshpan | Compositions and methods for cell killing |
| EP1948201A4 (en) | 2005-11-14 | 2013-12-25 | Valorisation Recherche Ltd Partnership | PHARMACEUTICAL COMPOSITIONS WITH POLYMER BINDERS WITH NON-HYDROLYZABLE COVALENT BINDINGS AND THEIR USE IN THE TREATMENT OF CELIAC DISEASE |
| US7915235B2 (en) * | 2006-03-20 | 2011-03-29 | Brian Dieckgraefe | High affinity ligands bind to clostridium difficile toxin A |
| TW200829286A (en) * | 2006-09-06 | 2008-07-16 | Genzyme Corp | Polystyrene sulfonate polymer tablets, their preparation and use |
| CN103958552B (zh) * | 2011-11-16 | 2016-11-16 | 东曹有机化学株式会社 | 高纯度对苯乙烯磺酸钠的制造方法以及聚苯乙烯磺酸钠的制造方法 |
| KR102545700B1 (ko) * | 2020-12-08 | 2023-06-21 | 동아대학교 산학협력단 | 폴리스티렌설폰산 금속염, 이의 제조방법 및 이를 포함하는 조성물 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3224941A (en) * | 1963-01-21 | 1965-12-21 | Lilly Co Eli | Resin compositions and method for controlling diarrhea |
| DE1480628C3 (de) * | 1965-10-28 | 1975-02-06 | Alfred 2000 Hamburg Wriedt | Kupplung für einen Förderkarrenzug |
| US3466365A (en) * | 1967-07-24 | 1969-09-09 | White Lab Inc | Antiviral compositions and method of use |
| US3987163A (en) * | 1973-07-27 | 1976-10-19 | Burton, Parsons And Company, Inc. | Polystyrene sulfonate containing opthalmic solutions |
| IE44690B1 (en) * | 1976-02-04 | 1982-02-24 | Rohm & Haas | Pharmaceutical compositions containing polyvinylbenzenosulfonic acids |
| US4395392A (en) * | 1980-06-24 | 1983-07-26 | Adria Laboratories Inc. | Method for treating kidney stones |
| US4362711A (en) * | 1980-07-11 | 1982-12-07 | Evreka Inc. | Blood cholesterol level reducing agent and method |
| US5171738A (en) * | 1982-10-04 | 1992-12-15 | Toray Industries, Inc. | Method of treating malignant tumors |
| US5435821A (en) * | 1985-12-12 | 1995-07-25 | Exxon Research & Engineering Co. | Controlled release vegetation enhancement agents coated with sulfonated polymers, method of production and prcesses of use |
| US5071759A (en) * | 1986-05-30 | 1991-12-10 | The United States Of America As Represented By The Secretary Of The Army | Hybridoma cell lines and monoclonal antibodies to clostridum difficile toxins A and B |
| US4837015A (en) * | 1987-03-05 | 1989-06-06 | Carolina Medical Products Company, Inc. | Alkali metal ion-charged, cation exchanger and use thereof to adjust sodium, potassium and calcium body fluid levels |
| IL90388A (en) * | 1988-05-26 | 1993-08-18 | Duphar Int Res | Pharmaceutical compositions having anti- endotoxic activity containing a novel active fraction from lactulose syrup, and a method for its preparation |
| US5149523A (en) * | 1989-06-20 | 1992-09-22 | Aktiebolaget Hassle | Polystyrenesulfonate-drug complex and solid dosage forms thereof |
| US5093130A (en) * | 1989-09-26 | 1992-03-03 | Plant Genetics | Powder coated hydrogel capsules |
| US5736139A (en) * | 1989-10-31 | 1998-04-07 | Ochidian Pharmaceuticals, Inc. | Treatment of Clostridium difficile induced disease |
| US5601823A (en) * | 1989-10-31 | 1997-02-11 | Ophidian Pharmaceuticals, Inc. | Avian antitoxins to clostridium difficle toxin A |
| US5231003A (en) * | 1990-05-11 | 1993-07-27 | Cambridge Bioscience Corporation | Monoclonal antibodies specific for toxin b of clostridium difficile |
| US5149543A (en) * | 1990-10-05 | 1992-09-22 | Massachusetts Institute Of Technology | Ionically cross-linked polymeric microcapsules |
| US5277820A (en) * | 1992-02-06 | 1994-01-11 | Hemocleanse, Inc. | Device and method for extracorporeal blood treatment |
| US5474765A (en) * | 1992-03-23 | 1995-12-12 | Ut Sw Medical Ctr At Dallas | Preparation and use of steroid-polyanionic polymer-based conjugates targeted to vascular endothelial cells |
| US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
| US5643562A (en) * | 1993-03-29 | 1997-07-01 | Queen's University Of Kingston | Method for treating amyloidosis |
| US5614559A (en) * | 1993-11-23 | 1997-03-25 | Procept Inc. | Compound for inhibiting HIV infectivity |
| US5484773A (en) * | 1994-02-14 | 1996-01-16 | Alberta Research Council | Treatment of antibiotic associated diarrhea |
| CA2183428A1 (en) * | 1994-03-11 | 1995-09-14 | John J. Baldwin | Sulfonamide derivatives and their use |
| AU702405B2 (en) * | 1994-09-06 | 1999-02-18 | Immucell Corporation | Therapeutic treatment of clostridium difficile associated diseases |
| EP0704697A1 (en) * | 1994-09-27 | 1996-04-03 | General Motors Corporation | Exhaust sensor including a ceramic tube in metal tube package |
| US5610023A (en) * | 1995-03-31 | 1997-03-11 | Lee Laboratories, Inc. | Method of purification of clostridium difficile toxin A and production of mono-specific antibodies |
| DE19515554C2 (de) * | 1995-04-27 | 1999-06-17 | Braun Melsungen Ag | Verwendung eines Mittels und Vorrichtung zur simultanen extrakorporalen Elimination von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus Vollblut oder/und Blutplasma |
| US6034129A (en) * | 1996-06-24 | 2000-03-07 | Geltex Pharmaceuticals, Inc. | Ionic polymers as anti-infective agents |
| US5800803A (en) * | 1997-02-10 | 1998-09-01 | Colgate-Palmolive Company | Oral composition exhibiting enhanced uptake by dental tissue of noncationic antibacterial agents |
| CA2294148A1 (en) * | 1997-06-20 | 1998-12-30 | Hitomi Izumi | Gelled composition |
| US6060235A (en) * | 1997-09-19 | 2000-05-09 | Geltex Pharmaceuticals, Inc. | Antiviral polymers comprising acid functional groups and hydrophobic groups |
| US6290947B1 (en) * | 1997-09-19 | 2001-09-18 | Geltex Pharmaceuticals, Inc. | Ionic polymers as toxin-binding agents |
| US6007803A (en) * | 1997-09-19 | 1999-12-28 | Geltex Pharmaceuticals, Inc. | Ionic polymers as toxin binding agents |
| WO1999020285A1 (en) * | 1997-10-16 | 1999-04-29 | Sanwa Kagaku Kenkyusho Co., Ltd. | Gel preparations containing polystyrenesulfonate |
| US6221248B1 (en) * | 1998-03-23 | 2001-04-24 | Ionics Incorporated | Styrene sulfonate cation exchange membrane |
| US6146622A (en) * | 1998-10-27 | 2000-11-14 | Alcon Laboratories, Inc. | Use of certain anionic amino acid based surfactants to enhance antimicrobial effectiveness of topically administrable pharmaceutical compositions |
| US6290946B1 (en) * | 1999-05-13 | 2001-09-18 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders and antibacterial agents |
| US6270755B1 (en) * | 1999-05-13 | 2001-08-07 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders |
| CA2314494A1 (en) * | 2000-05-02 | 2001-11-02 | Geltex Pharmaceuticals, Inc. | Anionic polymers as species specific antibacterial agents |
| US6537538B2 (en) * | 2000-12-18 | 2003-03-25 | Rush-Presbyterian-St. Luke's Medical Center | Method for the prevention, inhibition, or treatment of vaginitis and/or bacterial vaginosis using polystyrene sulfonate |
| CA2492211A1 (en) * | 2002-07-22 | 2004-01-29 | Genzyme Corporation | Poly(potassium and sodium styrene sulfonate), its manufacture and its uses |
| KR100714648B1 (ko) * | 2005-12-02 | 2007-05-07 | 삼성전자주식회사 | 인쇄 회로 기판 |
-
2003
- 2003-07-18 CA CA002492211A patent/CA2492211A1/en not_active Abandoned
- 2003-07-18 EP EP03765733A patent/EP1542706A1/en not_active Withdrawn
- 2003-07-18 CN CNA2008101286640A patent/CN101319023A/zh active Pending
- 2003-07-18 NZ NZ537594A patent/NZ537594A/en not_active IP Right Cessation
- 2003-07-18 WO PCT/US2003/022514 patent/WO2004009100A1/en not_active Ceased
- 2003-07-18 MX MXPA05000687A patent/MXPA05000687A/es active IP Right Grant
- 2003-07-18 CN CNA2007100917612A patent/CN101081230A/zh active Pending
- 2003-07-18 JP JP2004523573A patent/JP4476807B2/ja not_active Expired - Lifetime
- 2003-07-18 AU AU2003254007A patent/AU2003254007B2/en not_active Ceased
- 2003-07-18 KR KR1020057001187A patent/KR20050030208A/ko not_active Withdrawn
- 2003-07-18 BR BR0312884-9A patent/BR0312884A/pt not_active IP Right Cessation
- 2003-07-18 CN CNB038173832A patent/CN100411625C/zh not_active Expired - Fee Related
-
2005
- 2005-01-20 US US11/039,351 patent/US20050214246A1/en not_active Abandoned
-
2006
- 2006-07-18 US US11/488,897 patent/US20070053865A1/en not_active Abandoned
- 2006-07-18 US US11/488,896 patent/US20070053864A1/en not_active Abandoned
-
2008
- 2008-08-06 US US12/186,911 patent/US20090175818A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20070053864A1 (en) | 2007-03-08 |
| US20050214246A1 (en) | 2005-09-29 |
| BR0312884A (pt) | 2005-06-14 |
| CN100411625C (zh) | 2008-08-20 |
| WO2004009100A1 (en) | 2004-01-29 |
| AU2003254007B2 (en) | 2007-08-23 |
| CN101081230A (zh) | 2007-12-05 |
| JP2006502249A (ja) | 2006-01-19 |
| AU2003254007A1 (en) | 2004-02-09 |
| CA2492211A1 (en) | 2004-01-29 |
| US20090175818A1 (en) | 2009-07-09 |
| MXPA05000687A (es) | 2005-04-08 |
| CN1671401A (zh) | 2005-09-21 |
| HK1082417A1 (en) | 2006-06-09 |
| CN101319023A (zh) | 2008-12-10 |
| NZ537594A (en) | 2008-05-30 |
| US20070053865A1 (en) | 2007-03-08 |
| KR20050030208A (ko) | 2005-03-29 |
| EP1542706A1 (en) | 2005-06-22 |
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