JP4459435B2 - 新規ｔ細胞膜蛋白質（ｔｉｒｃ７）、ペプチドおよびそれに由来する抗体ならびにその使用 - Google Patents

新規ｔ細胞膜蛋白質（ｔｉｒｃ７）、ペプチドおよびそれに由来する抗体ならびにその使用 Download PDF

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JP4459435B2
JP4459435B2 JP2000508792A JP2000508792A JP4459435B2 JP 4459435 B2 JP4459435 B2 JP 4459435B2 JP 2000508792 A JP2000508792 A JP 2000508792A JP 2000508792 A JP2000508792 A JP 2000508792A JP 4459435 B2 JP4459435 B2 JP 4459435B2
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cell
tirc7
leu
protein
ala
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JP2000508792A
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Japanese (ja)
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JP2001514852A (ja
JP2001514852A5 (https=
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ナラン ウトゥク
スティーブン アール． グランス
エドガー エル． ミルフォード
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2000508792A 1997-08-29 1998-08-28 新規ｔ細胞膜蛋白質（ｔｉｒｃ７）、ペプチドおよびそれに由来する抗体ならびにその使用 Expired - Lifetime JP4459435B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19738710A DE19738710A1 (de) 1997-08-29 1997-08-29 Verwendung von TIRC7 zur Herstellung von Mitteln zur Inhibition der Immunantwort
DE19738710.1 1998-02-12
DE29802653 1998-02-12
DE29802653.8 1998-02-12
PCT/EP1998/005462 WO1999011782A1 (en) 1997-08-29 1998-08-28 T-cell membrane protein (tirc7), peptides and antibodies derived therefrom and uses thereof

Publications (3)

Publication Number Publication Date
JP2001514852A JP2001514852A (ja) 2001-09-18
JP2001514852A5 JP2001514852A5 (https=) 2006-01-05
JP4459435B2 true JP4459435B2 (ja) 2010-04-28

Family

ID=26039678

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000508792A Expired - Lifetime JP4459435B2 (ja) 1997-08-29 1998-08-28 新規ｔ細胞膜蛋白質（ｔｉｒｃ７）、ペプチドおよびそれに由来する抗体ならびにその使用

Country Status (10)

Country Link
EP (2) EP0996726B1 (https=)
JP (1) JP4459435B2 (https=)
AT (1) ATE256185T1 (https=)
AU (1) AU751151C (https=)
CA (1) CA2301499C (https=)
DE (1) DE69820449T2 (https=)
DK (1) DK0996726T3 (https=)
ES (1) ES2213295T3 (https=)
PT (1) PT996726E (https=)
WO (1) WO1999011782A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL134830A0 (en) * 2000-03-01 2001-05-20 Chay 13 Medical Res Group N V Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them
AU2001263888A1 (en) * 2000-05-03 2001-11-12 Genpat77 Pharmacogenetics Ag Uses of tgap7 for the modulation of leucocyte activation
WO2002036149A2 (en) * 2000-10-30 2002-05-10 Nalan Utku Methods for obtaining inhibitors of t-cell membrane protein (tirc7) ligand binding and uses thereof
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7026121B1 (en) 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
WO2003025000A2 (en) * 2001-09-17 2003-03-27 Nalan Utku Peptides capable of modulating immune response
US20050118178A1 (en) * 2001-11-27 2005-06-02 Nalan Utku Use of t-cell immune response cdna7 (tirc7) in angiogenic and anti-angiogenic therapy
AU2002366746A1 (en) * 2001-12-21 2003-07-09 Genpat77 Pharmacogenetics Ag Anti-tirc7 antibodies in therapy of inflammatory diseases
US20060165684A1 (en) 2001-12-21 2006-07-27 Nalan Utku Therapeutic anti-tirc7 antibodies for use in immune related and other diseases
JP2005531500A (ja) * 2002-02-04 2005-10-20 ウトゥク ナラン 貪食細胞およびリンパ細胞集団に対する影響を調節するための、ｔｉｒｃ７を用いた組成物および方法
WO2003091285A1 (en) * 2002-04-26 2003-11-06 Genpat77 Pharmacogenetics Ag Bispecific molecules for use in therapy and diagnosis of immune related and other diseases
JP2006506954A (ja) * 2002-04-29 2006-03-02 ゲンパト７７ ファーマコジェネティクス エージー Ｔｃｒ及びｔｉｒｃ７に結合する新規な抗体、並びに治療及び診断におけるその使用
US20110183921A1 (en) * 2005-05-17 2011-07-28 Jojomed Gmbh Peptides capable of modulating the function of tirc7
WO2006122791A2 (en) * 2005-05-17 2006-11-23 Genpat77 Pharmacogenetics Ag Tirc7 as marker for detecting early immune activation
DE202011103324U1 (de) 2011-07-12 2012-01-02 Nekonal S.A.R.L. Therapeutische anti-TIRC7 Antikörper für die Verwendung in Immun und anderen Krankheiten
AU2017309306A1 (en) 2016-08-09 2019-02-28 Nekonal S.A.R.L. TIRC7 based diagnostic and therapy of cancer
EP3497235A1 (en) 2016-08-10 2019-06-19 Nekonal S.A.R.L. Tirc7 based diagnostic and therapy of solid cancer
US20220288120A1 (en) 2019-08-14 2022-09-15 Nekonal S.A.R.L. Method for producing engineered tirc7 specific t-regulatory cells (tregs)

Also Published As

Publication number Publication date
AU751151B2 (en) 2002-08-08
PT996726E (pt) 2004-04-30
DE69820449D1 (de) 2004-01-22
EP0996726B1 (en) 2003-12-10
ATE256185T1 (de) 2003-12-15
AU9265498A (en) 1999-03-22
EP1350848A2 (en) 2003-10-08
WO1999011782A1 (en) 1999-03-11
AU751151C (en) 2006-09-14
DE69820449T2 (de) 2005-03-10
DK0996726T3 (da) 2004-04-13
ES2213295T3 (es) 2004-08-16
EP1350848A3 (en) 2004-02-04
CA2301499A1 (en) 1999-03-11
CA2301499C (en) 2010-01-26
JP2001514852A (ja) 2001-09-18
EP0996726A1 (en) 2000-05-03

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