AU751151C - T-cell membrane protein (TIRC7), peptides and antibodies derived therefrom and uses thereof - Google Patents

T-cell membrane protein (TIRC7), peptides and antibodies derived therefrom and uses thereof

Info

Publication number
AU751151C
AU751151C AU92654/98A AU9265498A AU751151C AU 751151 C AU751151 C AU 751151C AU 92654/98 A AU92654/98 A AU 92654/98A AU 9265498 A AU9265498 A AU 9265498A AU 751151 C AU751151 C AU 751151C
Authority
AU
Australia
Prior art keywords
cell
tirc7
protein
antibody
membrane protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU92654/98A
Other languages
English (en)
Other versions
AU751151B2 (en
AU9265498A (en
Inventor
Steven R Gullans
Edgar L. Milford
Nalan Utku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Original Assignee
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19738710A external-priority patent/DE19738710A1/de
Application filed by Brigham and Womens Hospital Inc filed Critical Brigham and Womens Hospital Inc
Publication of AU9265498A publication Critical patent/AU9265498A/en
Publication of AU751151B2 publication Critical patent/AU751151B2/en
Application granted granted Critical
Publication of AU751151C publication Critical patent/AU751151C/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU92654/98A 1997-08-29 1998-08-28 T-cell membrane protein (TIRC7), peptides and antibodies derived therefrom and uses thereof Ceased AU751151C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19738710A DE19738710A1 (de) 1997-08-29 1997-08-29 Verwendung von TIRC7 zur Herstellung von Mitteln zur Inhibition der Immunantwort
DE19738710 1997-08-29
DE29802653 1998-02-12
DE29802653 1998-02-12
PCT/EP1998/005462 WO1999011782A1 (en) 1997-08-29 1998-08-28 T-cell membrane protein (tirc7), peptides and antibodies derived therefrom and uses thereof

Publications (3)

Publication Number Publication Date
AU9265498A AU9265498A (en) 1999-03-22
AU751151B2 AU751151B2 (en) 2002-08-08
AU751151C true AU751151C (en) 2006-09-14

Family

ID=26039678

Family Applications (1)

Application Number Title Priority Date Filing Date
AU92654/98A Ceased AU751151C (en) 1997-08-29 1998-08-28 T-cell membrane protein (TIRC7), peptides and antibodies derived therefrom and uses thereof

Country Status (10)

Country Link
EP (2) EP0996726B1 (https=)
JP (1) JP4459435B2 (https=)
AT (1) ATE256185T1 (https=)
AU (1) AU751151C (https=)
CA (1) CA2301499C (https=)
DE (1) DE69820449T2 (https=)
DK (1) DK0996726T3 (https=)
ES (1) ES2213295T3 (https=)
PT (1) PT996726E (https=)
WO (1) WO1999011782A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL134830A0 (en) * 2000-03-01 2001-05-20 Chay 13 Medical Res Group N V Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them
AU2001263888A1 (en) * 2000-05-03 2001-11-12 Genpat77 Pharmacogenetics Ag Uses of tgap7 for the modulation of leucocyte activation
WO2002036149A2 (en) * 2000-10-30 2002-05-10 Nalan Utku Methods for obtaining inhibitors of t-cell membrane protein (tirc7) ligand binding and uses thereof
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7026121B1 (en) 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
WO2003025000A2 (en) * 2001-09-17 2003-03-27 Nalan Utku Peptides capable of modulating immune response
US20050118178A1 (en) * 2001-11-27 2005-06-02 Nalan Utku Use of t-cell immune response cdna7 (tirc7) in angiogenic and anti-angiogenic therapy
AU2002366746A1 (en) * 2001-12-21 2003-07-09 Genpat77 Pharmacogenetics Ag Anti-tirc7 antibodies in therapy of inflammatory diseases
US20060165684A1 (en) 2001-12-21 2006-07-27 Nalan Utku Therapeutic anti-tirc7 antibodies for use in immune related and other diseases
JP2005531500A (ja) * 2002-02-04 2005-10-20 ウトゥク ナラン 貪食細胞およびリンパ細胞集団に対する影響を調節するための、tirc7を用いた組成物および方法
WO2003091285A1 (en) * 2002-04-26 2003-11-06 Genpat77 Pharmacogenetics Ag Bispecific molecules for use in therapy and diagnosis of immune related and other diseases
JP2006506954A (ja) * 2002-04-29 2006-03-02 ゲンパト77 ファーマコジェネティクス エージー Tcr及びtirc7に結合する新規な抗体、並びに治療及び診断におけるその使用
US20110183921A1 (en) * 2005-05-17 2011-07-28 Jojomed Gmbh Peptides capable of modulating the function of tirc7
WO2006122791A2 (en) * 2005-05-17 2006-11-23 Genpat77 Pharmacogenetics Ag Tirc7 as marker for detecting early immune activation
DE202011103324U1 (de) 2011-07-12 2012-01-02 Nekonal S.A.R.L. Therapeutische anti-TIRC7 Antikörper für die Verwendung in Immun und anderen Krankheiten
AU2017309306A1 (en) 2016-08-09 2019-02-28 Nekonal S.A.R.L. TIRC7 based diagnostic and therapy of cancer
EP3497235A1 (en) 2016-08-10 2019-06-19 Nekonal S.A.R.L. Tirc7 based diagnostic and therapy of solid cancer
US20220288120A1 (en) 2019-08-14 2022-09-15 Nekonal S.A.R.L. Method for producing engineered tirc7 specific t-regulatory cells (tregs)

Also Published As

Publication number Publication date
AU751151B2 (en) 2002-08-08
PT996726E (pt) 2004-04-30
DE69820449D1 (de) 2004-01-22
EP0996726B1 (en) 2003-12-10
ATE256185T1 (de) 2003-12-15
AU9265498A (en) 1999-03-22
EP1350848A2 (en) 2003-10-08
WO1999011782A1 (en) 1999-03-11
DE69820449T2 (de) 2005-03-10
DK0996726T3 (da) 2004-04-13
JP4459435B2 (ja) 2010-04-28
ES2213295T3 (es) 2004-08-16
EP1350848A3 (en) 2004-02-04
CA2301499A1 (en) 1999-03-11
CA2301499C (en) 2010-01-26
JP2001514852A (ja) 2001-09-18
EP0996726A1 (en) 2000-05-03

Similar Documents

Publication Publication Date Title
AU751151C (en) T-cell membrane protein (TIRC7), peptides and antibodies derived therefrom and uses thereof
EP0741784B1 (en) Ligand (act-4-l) to a receptor on the surface of activated cd4+ t-cells
US6338851B1 (en) Method of suppressing an immune response to a transplanted organ or tissue by administering an OX-2 protein
EP0726952B1 (en) Receptor on the surface of activated t-cells:acts-4
WO1995029236A9 (en) Lymphocyte activation antigens and antibodies thereto
US7931901B2 (en) T-cell membrane protein (TIRC7), peptides and antibodies derived therefrom and uses thereof
US20110189181A1 (en) Use of agents derived from CEACAM1 for the treatment of inflammatory diseases
US20050048067A1 (en) Peptides capable of modulating immune response
US5646251A (en) Alloreaction-associated antigen (ARAG): a novel member of the immunoglobulin gene superfamily
EP0795014A1 (en) Purified genes encoding mammalian cell surface antigens; proteins and antibodies
EP1278535B1 (en) Uses of tgap7 for the modulation of leucocyte activation
CA2525499C (en) Ligand (act-4-l) to a receptor on the surface of activated cd4+ t-cells
HK1001462B (en) Ligand (act-4-l) to a receptor on the surface of activated cd4+ t-cells
MXPA97003956A (en) Purified genes that codify antigens of surface of mammali cells, proteins and antibody
AU2002338724A1 (en) Peptides capable of modulating immune response
HK1001464B (en) Receptor on the surface of activated t-cells:acts-4

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND SECOND APPLICANT S NAME TO READ: NALAN UTKU