ES2213295T3 - Proteina de membrana de celulas t, peptidos y anticuerpos derivados a partir de estos y utilizaciones de los mismos. - Google Patents

Proteina de membrana de celulas t, peptidos y anticuerpos derivados a partir de estos y utilizaciones de los mismos.

Info

Publication number
ES2213295T3
ES2213295T3 ES98945293T ES98945293T ES2213295T3 ES 2213295 T3 ES2213295 T3 ES 2213295T3 ES 98945293 T ES98945293 T ES 98945293T ES 98945293 T ES98945293 T ES 98945293T ES 2213295 T3 ES2213295 T3 ES 2213295T3
Authority
ES
Spain
Prior art keywords
cell
tirc7
cells
protein
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98945293T
Other languages
English (en)
Spanish (es)
Inventor
Nalan Utku
Steven R. Gullans
Edgar L. Milford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Original Assignee
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19738710A external-priority patent/DE19738710A1/de
Application filed by Brigham and Womens Hospital Inc filed Critical Brigham and Womens Hospital Inc
Application granted granted Critical
Publication of ES2213295T3 publication Critical patent/ES2213295T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES98945293T 1997-08-29 1998-08-28 Proteina de membrana de celulas t, peptidos y anticuerpos derivados a partir de estos y utilizaciones de los mismos. Expired - Lifetime ES2213295T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19738710A DE19738710A1 (de) 1997-08-29 1997-08-29 Verwendung von TIRC7 zur Herstellung von Mitteln zur Inhibition der Immunantwort
DE19738710 1997-08-29
DE29802653U 1998-02-12
DE29802653 1998-02-12

Publications (1)

Publication Number Publication Date
ES2213295T3 true ES2213295T3 (es) 2004-08-16

Family

ID=26039678

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98945293T Expired - Lifetime ES2213295T3 (es) 1997-08-29 1998-08-28 Proteina de membrana de celulas t, peptidos y anticuerpos derivados a partir de estos y utilizaciones de los mismos.

Country Status (10)

Country Link
EP (2) EP0996726B1 (https=)
JP (1) JP4459435B2 (https=)
AT (1) ATE256185T1 (https=)
AU (1) AU751151C (https=)
CA (1) CA2301499C (https=)
DE (1) DE69820449T2 (https=)
DK (1) DK0996726T3 (https=)
ES (1) ES2213295T3 (https=)
PT (1) PT996726E (https=)
WO (1) WO1999011782A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL134830A0 (en) * 2000-03-01 2001-05-20 Chay 13 Medical Res Group N V Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them
AU2001263888A1 (en) * 2000-05-03 2001-11-12 Genpat77 Pharmacogenetics Ag Uses of tgap7 for the modulation of leucocyte activation
WO2002036149A2 (en) * 2000-10-30 2002-05-10 Nalan Utku Methods for obtaining inhibitors of t-cell membrane protein (tirc7) ligand binding and uses thereof
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7026121B1 (en) 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
WO2003025000A2 (en) * 2001-09-17 2003-03-27 Nalan Utku Peptides capable of modulating immune response
US20050118178A1 (en) * 2001-11-27 2005-06-02 Nalan Utku Use of t-cell immune response cdna7 (tirc7) in angiogenic and anti-angiogenic therapy
AU2002366746A1 (en) * 2001-12-21 2003-07-09 Genpat77 Pharmacogenetics Ag Anti-tirc7 antibodies in therapy of inflammatory diseases
US20060165684A1 (en) 2001-12-21 2006-07-27 Nalan Utku Therapeutic anti-tirc7 antibodies for use in immune related and other diseases
JP2005531500A (ja) * 2002-02-04 2005-10-20 ウトゥク ナラン 貪食細胞およびリンパ細胞集団に対する影響を調節するための、ｔｉｒｃ７を用いた組成物および方法
WO2003091285A1 (en) * 2002-04-26 2003-11-06 Genpat77 Pharmacogenetics Ag Bispecific molecules for use in therapy and diagnosis of immune related and other diseases
JP2006506954A (ja) * 2002-04-29 2006-03-02 ゲンパト７７ ファーマコジェネティクス エージー Ｔｃｒ及びｔｉｒｃ７に結合する新規な抗体、並びに治療及び診断におけるその使用
US20110183921A1 (en) * 2005-05-17 2011-07-28 Jojomed Gmbh Peptides capable of modulating the function of tirc7
WO2006122791A2 (en) * 2005-05-17 2006-11-23 Genpat77 Pharmacogenetics Ag Tirc7 as marker for detecting early immune activation
DE202011103324U1 (de) 2011-07-12 2012-01-02 Nekonal S.A.R.L. Therapeutische anti-TIRC7 Antikörper für die Verwendung in Immun und anderen Krankheiten
AU2017309306A1 (en) 2016-08-09 2019-02-28 Nekonal S.A.R.L. TIRC7 based diagnostic and therapy of cancer
EP3497235A1 (en) 2016-08-10 2019-06-19 Nekonal S.A.R.L. Tirc7 based diagnostic and therapy of solid cancer
US20220288120A1 (en) 2019-08-14 2022-09-15 Nekonal S.A.R.L. Method for producing engineered tirc7 specific t-regulatory cells (tregs)

Also Published As

Publication number Publication date
AU751151B2 (en) 2002-08-08
PT996726E (pt) 2004-04-30
DE69820449D1 (de) 2004-01-22
EP0996726B1 (en) 2003-12-10
ATE256185T1 (de) 2003-12-15
AU9265498A (en) 1999-03-22
EP1350848A2 (en) 2003-10-08
WO1999011782A1 (en) 1999-03-11
AU751151C (en) 2006-09-14
DE69820449T2 (de) 2005-03-10
DK0996726T3 (da) 2004-04-13
JP4459435B2 (ja) 2010-04-28
EP1350848A3 (en) 2004-02-04
CA2301499A1 (en) 1999-03-11
CA2301499C (en) 2010-01-26
JP2001514852A (ja) 2001-09-18
EP0996726A1 (en) 2000-05-03

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