JP4414654B2 - サンプル分子を単離および標識するための方法 - Google Patents

サンプル分子を単離および標識するための方法 Download PDF

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JP4414654B2
JP4414654B2 JP2002589762A JP2002589762A JP4414654B2 JP 4414654 B2 JP4414654 B2 JP 4414654B2 JP 2002589762 A JP2002589762 A JP 2002589762A JP 2002589762 A JP2002589762 A JP 2002589762A JP 4414654 B2 JP4414654 B2 JP 4414654B2
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composition
polypeptide
sample
molecule
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JP2005503540A (ja
JP2005503540A5 (https=
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ルドルフ エイチ. アーバーソルド,
フイリン ゾウ,
ビート リスト,
ジョージ ジェイ. ヴェラ,
サブハシス パーカヤスサ,
サシ ピライ,
Original Assignee
ザ インスティチュート フォー システムズ バイオロジー
ユニヴァーシティ オブ ワシントン
アプライド バイオシステムズ, エルエルシー
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Peptides Or Proteins (AREA)
JP2002589762A 2001-05-14 2002-05-14 サンプル分子を単離および標識するための方法 Expired - Lifetime JP4414654B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/858,198 US7183116B2 (en) 2001-05-14 2001-05-14 Methods for isolation and labeling of sample molecules
PCT/US2002/015500 WO2002093131A2 (en) 2001-05-14 2002-05-14 Methods for isolating and labeling sample molecules

Related Child Applications (1)

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JP2009113092A Division JP2009175157A (ja) 2001-05-14 2009-05-07 サンプル分子を単離および標識するための方法

Publications (3)

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JP2005503540A JP2005503540A (ja) 2005-02-03
JP2005503540A5 JP2005503540A5 (https=) 2008-11-06
JP4414654B2 true JP4414654B2 (ja) 2010-02-10

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JP2002589762A Expired - Lifetime JP4414654B2 (ja) 2001-05-14 2002-05-14 サンプル分子を単離および標識するための方法
JP2009113092A Withdrawn JP2009175157A (ja) 2001-05-14 2009-05-07 サンプル分子を単離および標識するための方法

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US (3) US7183116B2 (https=)
EP (1) EP1456632B1 (https=)
JP (2) JP4414654B2 (https=)
CN (1) CN1602422B (https=)
AT (1) ATE495436T1 (https=)
AU (1) AU2002303760B2 (https=)
CA (1) CA2447874C (https=)
DE (1) DE60238940D1 (https=)
WO (1) WO2002093131A2 (https=)

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US8614303B2 (en) * 2001-12-11 2013-12-24 University Of Medicine And Dentistry Diagnostic methods for ubiquinated protein profiling
CN1617938A (zh) 2002-01-16 2005-05-18 戴诺生物技术有限公司 从单个样品中分离核酸和蛋白质的方法
AU2003220188A1 (en) * 2002-03-11 2003-09-29 President And Fellows Of Harvard College Detection and quantification of modified proteins
AU2003224674A1 (en) * 2002-03-11 2003-09-29 Hk Pharmaceuticals, Inc. Compounds and methods for analyzing the proteome
EP1514107B1 (en) * 2002-06-03 2013-05-15 The Institute for Systems Biology Methods for quantitative proteome analysis of glycoproteins
US20070269895A1 (en) * 2002-06-03 2007-11-22 The Institute For Systems Biology Methods for quantitative proteome analysis of glycoproteins
JP2004170195A (ja) * 2002-11-19 2004-06-17 Reverse Proteomics Research Institute Co Ltd タンパク質の固定化方法
GB0229287D0 (en) * 2002-12-16 2003-01-22 Dna Res Innovations Ltd Polyfunctional reagents
WO2004064972A2 (en) * 2003-01-16 2004-08-05 Hk Pharmaceuticals, Inc. Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
WO2005007677A2 (en) * 2003-07-10 2005-01-27 The Institute For Systems Biology Affinity capture of peptides by microarray and related methods
US20050113584A1 (en) * 2003-07-14 2005-05-26 Irm Llc Methods for the preparation of rhodamine
WO2005007663A2 (en) * 2003-07-14 2005-01-27 Irm Llc Fluorogenic enzyme substrates and uses thereof
WO2005015239A2 (en) * 2003-08-07 2005-02-17 Cornell Research Foundation, Inc. Method for n-terminal labeling of proteins
JP4363935B2 (ja) * 2003-09-17 2009-11-11 株式会社豊田中央研究所 生体物質の光固定化・回収方法及び表面プラズモン共鳴センサー
EP1668146B1 (en) 2003-09-25 2014-11-12 Life Technologies Corporation Homogeneous populations of molecules
WO2006017208A1 (en) * 2004-07-12 2006-02-16 Applera Corporation Mass tags for quantitative analyses
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WO2006011673A1 (ja) * 2004-07-30 2006-02-02 Reverse Proteomics Research Institute Co., Ltd. 光切断型リンカーを利用したリガンド固定化固相担体
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US20060134694A1 (en) * 2004-12-22 2006-06-22 Intel Corporation Methods of protein profiling by thiolation
WO2006094185A2 (en) * 2005-03-03 2006-09-08 Dmi Biosciences Inc. Quantification of proteins
WO2007000669A2 (en) * 2005-06-07 2007-01-04 Centre National De La Recherche Scientifique (Cnrs) Use of conjugates with linkers cleavable by photodissociation or fragmentation for mass spectrometry analysis of tissue sections
GB0515323D0 (en) * 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
US7906341B2 (en) * 2006-06-30 2011-03-15 Dh Technologies Development Pte, Ltd. Methods, mixtures, kits and compositions pertaining to analyte determination
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US20040110186A1 (en) 2004-06-10
EP1456632A2 (en) 2004-09-15
EP1456632A4 (en) 2005-04-20
AU2002303760B2 (en) 2008-04-10
US20020168644A1 (en) 2002-11-14
CN1602422B (zh) 2011-06-08
US7364911B2 (en) 2008-04-29
CA2447874A1 (en) 2002-11-21
US20040265810A1 (en) 2004-12-30
EP1456632B1 (en) 2011-01-12
WO2002093131A3 (en) 2004-05-27
WO2002093131A2 (en) 2002-11-21
JP2005503540A (ja) 2005-02-03
JP2009175157A (ja) 2009-08-06
ATE495436T1 (de) 2011-01-15
CN1602422A (zh) 2005-03-30
CA2447874C (en) 2010-08-31
DE60238940D1 (de) 2011-02-24
US7183116B2 (en) 2007-02-27

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