JP4410857B2 - ヒドロキシ酸から誘導されたモノマー及びそれから調製されたポリマー - Google Patents
ヒドロキシ酸から誘導されたモノマー及びそれから調製されたポリマー Download PDFInfo
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- JP4410857B2 JP4410857B2 JP53600898A JP53600898A JP4410857B2 JP 4410857 B2 JP4410857 B2 JP 4410857B2 JP 53600898 A JP53600898 A JP 53600898A JP 53600898 A JP53600898 A JP 53600898A JP 4410857 B2 JP4410857 B2 JP 4410857B2
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- amide
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- 239000001257 hydrogen Substances 0.000 claims abstract description 11
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- 238000000338 in vitro Methods 0.000 claims description 9
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- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 4
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 3
- 150000002431 hydrogen Chemical class 0.000 claims description 3
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
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- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
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Images
Classifications
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- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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- A61L31/148—Materials at least partially resorbable by the body
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- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
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- C08G63/6854—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen derived from polycarboxylic acids and polyhydroxy compounds
- C08G63/6858—Polycarboxylic acids and polyhydroxy compounds in which at least one of the two components contains aliphatic unsaturation
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- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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- C08G64/04—Aromatic polycarbonates
- C08G64/045—Aromatic polycarbonates containing aliphatic unsaturation
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- C08G64/12—Aromatic polycarbonates not containing aliphatic unsaturation containing atoms other than carbon, hydrogen or oxygen containing nitrogen
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- C08G64/1608—Aliphatic-aromatic or araliphatic polycarbonates saturated
- C08G64/1625—Aliphatic-aromatic or araliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen
- C08G64/1641—Aliphatic-aromatic or araliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen containing nitrogen
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
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- C08G64/183—Block or graft polymers containing polyether sequences
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- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
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- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
- C08G65/3311—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing a hydroxy group
- C08G65/3314—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing a hydroxy group cyclic
- C08G65/3315—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing a hydroxy group cyclic aromatic
- C08G65/3317—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing a hydroxy group cyclic aromatic phenolic
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Landscapes
- Chemical & Material Sciences (AREA)
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- Polyesters Or Polycarbonates (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyamides (AREA)
- Materials For Medical Uses (AREA)
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- Manufacturing Of Micro-Capsules (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| US3821397P | 1997-02-18 | 1997-02-18 | |
| US60/038,213 | 1997-02-18 | ||
| US6465697P | 1997-11-07 | 1997-11-07 | |
| US6490597P | 1997-11-07 | 1997-11-07 | |
| US60/064,905 | 1997-11-07 | ||
| US60/064,656 | 1997-11-07 | ||
| PCT/US1998/003127 WO1998036013A1 (en) | 1997-02-18 | 1998-02-18 | Monomers derived from hydroxy acids and polymers prepared therefrom |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2008178161A Division JP4411355B2 (ja) | 1997-02-18 | 2008-07-08 | ヒドロキシ酸から誘導されたモノマー及びそれから調製されたポリマー |
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| JP2001514618A JP2001514618A (ja) | 2001-09-11 |
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| JP2008178161A Expired - Fee Related JP4411355B2 (ja) | 1997-02-18 | 2008-07-08 | ヒドロキシ酸から誘導されたモノマー及びそれから調製されたポリマー |
| JP2009188682A Pending JP2010006820A (ja) | 1997-02-18 | 2009-08-17 | ヒドロキシ酸から誘導されたモノマー及びそれから調製されたポリマー |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2008178161A Expired - Fee Related JP4411355B2 (ja) | 1997-02-18 | 2008-07-08 | ヒドロキシ酸から誘導されたモノマー及びそれから調製されたポリマー |
| JP2009188682A Pending JP2010006820A (ja) | 1997-02-18 | 2009-08-17 | ヒドロキシ酸から誘導されたモノマー及びそれから調製されたポリマー |
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| EP (1) | EP0961801B1 (enExample) |
| JP (3) | JP4410857B2 (enExample) |
| AT (1) | ATE259386T1 (enExample) |
| AU (1) | AU729552B2 (enExample) |
| CA (1) | CA2281614C (enExample) |
| DE (1) | DE69821600T2 (enExample) |
| MX (1) | MXPA99007662A (enExample) |
| WO (1) | WO1998036013A1 (enExample) |
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| US6120491A (en) * | 1997-11-07 | 2000-09-19 | The State University Rutgers | Biodegradable, anionic polymers derived from the amino acid L-tyrosine |
| AU729552B2 (en) * | 1997-02-18 | 2001-02-01 | Rutgers, The State University | Monomers derived from hydroxy acids and polymers prepared therefrom |
| US6468519B1 (en) | 1997-09-10 | 2002-10-22 | Rutgers, The State University Of New Jersey | Polyanhydrides with biologically active degradation products |
| US6486214B1 (en) | 1997-09-10 | 2002-11-26 | Rutgers, The State University Of New Jersey | Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby |
| US7122615B1 (en) | 1998-09-10 | 2006-10-17 | Rutgers, The State University Of New Jersey | Polyanhydrides with therapeutically useful degradation products |
| US6475477B1 (en) * | 1997-11-07 | 2002-11-05 | Rutgers, The State University | Radio-opaque polymer biomaterials |
| US6602497B1 (en) | 1997-11-07 | 2003-08-05 | Rutgers, The State University | Strictly alternating poly(alkylene oxide ether) copolymers |
| US6623521B2 (en) | 1998-02-17 | 2003-09-23 | Md3, Inc. | Expandable stent with sliding and locking radial elements |
| US8133421B2 (en) | 1999-02-23 | 2012-03-13 | Warsaw Orthopedic, Inc. | Methods of making shaped load-bearing osteoimplant |
| US20070233272A1 (en) * | 1999-02-23 | 2007-10-04 | Boyce Todd M | Shaped load-bearing osteoimplant and methods of making same |
| US6103255A (en) | 1999-04-16 | 2000-08-15 | Rutgers, The State University | Porous polymer scaffolds for tissue engineering |
| DE69917339T2 (de) * | 1999-04-16 | 2005-05-12 | Rutgers, The State University | Poröse polymere stützgewebe für gewebetechnologie |
| US6426145B1 (en) * | 1999-05-20 | 2002-07-30 | Scimed Life Systems, Inc. | Radiopaque compositions for visualization of medical devices |
| US6685928B2 (en) | 1999-12-07 | 2004-02-03 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods |
| US20040038948A1 (en) | 1999-12-07 | 2004-02-26 | Uhrich Kathryn E. | Therapeutic compositions and methods |
| AU784226B2 (en) * | 1999-12-31 | 2006-02-23 | Rutgers, The State University | Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix |
| CA2395892C (en) | 1999-12-31 | 2014-06-03 | Rutgers, The State University | Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release |
| US7521061B2 (en) | 1999-12-31 | 2009-04-21 | Rutgers, The State University Of New Jersey | Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix |
| CA2417389C (en) | 2000-07-27 | 2012-05-29 | Rutgers, The State University | Therapeutic polyesters and polyamides |
| AU2001279064A1 (en) | 2000-07-27 | 2002-02-13 | Rutgers, The State University | Therapeutic azo-compounds for drug delivery |
| US20060057179A1 (en) | 2002-02-07 | 2006-03-16 | Giroux Karen J | Therapeutic polyesters and polyamides |
| EP1673109B1 (en) | 2003-09-25 | 2019-03-20 | Rutgers, The State University of New Jersey | Inherently radiopaque polymeric products for embolotherapy |
| US7368169B2 (en) * | 2003-12-01 | 2008-05-06 | Rutgers, The State University Of New Jersey | Hydrazide compounds with angiogenic activity |
| JP2007519492A (ja) * | 2004-01-30 | 2007-07-19 | オステオテック,インコーポレイテッド | 脊椎融合のための積み重ねインプラント |
| RU2383558C2 (ru) | 2004-07-08 | 2010-03-10 | Рева Медикал, Инк. | Полимеры с кристаллизующимися боковыми цепями для медицинского применения |
| US8703113B2 (en) | 2004-07-08 | 2014-04-22 | Reva Medical Inc. | Side-chain crystallizable polymers for medical applications |
| US7763065B2 (en) | 2004-07-21 | 2010-07-27 | Reva Medical, Inc. | Balloon expandable crush-recoverable stent device |
| WO2006023130A2 (en) * | 2004-08-12 | 2006-03-02 | Surmodics, Inc. | Biodegradable controlled release bioactive agent delivery device |
| US20060034769A1 (en) * | 2004-08-13 | 2006-02-16 | Rutgers, The State University | Radiopaque polymeric stents |
| JP4982369B2 (ja) * | 2004-08-13 | 2012-07-25 | ラトガース,ザ ステート ユニバーシティ | 放射線不透過性の高分子ステント |
| US8292944B2 (en) | 2004-12-17 | 2012-10-23 | Reva Medical, Inc. | Slide-and-lock stent |
| US8007775B2 (en) | 2004-12-30 | 2011-08-30 | Advanced Cardiovascular Systems, Inc. | Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same |
| US7202325B2 (en) | 2005-01-14 | 2007-04-10 | Advanced Cardiovascular Systems, Inc. | Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles |
| US9149378B2 (en) | 2005-08-02 | 2015-10-06 | Reva Medical, Inc. | Axially nested slide and lock expandable device |
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| US8007526B2 (en) | 2005-12-01 | 2011-08-30 | Bezwada Biomedical, Llc | Difunctionalized aromatic compounds and polymers therefrom |
| US8287914B2 (en) | 2006-01-12 | 2012-10-16 | Rutgers, The State University Of New Jersey | Biomimetic hydroxyapatite synthesis |
| US8222308B2 (en) | 2006-04-07 | 2012-07-17 | The University Of Queensland | Porous polymer structures |
| EP2010597B1 (en) | 2006-04-07 | 2015-06-17 | The University of Queensland | Porous polymer blend structures |
| US8507639B2 (en) | 2006-09-11 | 2013-08-13 | Boston Scientific Scimed, Inc. | Radiopaque amide polymers and medical devices formed thereof |
| EP2102144A4 (en) | 2006-09-13 | 2011-03-23 | Univ Rutgers | ACTIVE SUBSTANCES AND THEIR OLIGOMERS AND POLYMERS |
| EP2079491B1 (en) * | 2006-10-17 | 2013-02-27 | Reva Medical, Inc. | N-substituted monomers and polymers |
| EP2079416A4 (en) * | 2006-10-30 | 2012-06-27 | Univ Rutgers | ELECTROSPIN MATRICES FOR DISPENSING HYDROPHILIC AND LIPOPHILLE COMPOUNDS |
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Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2621916B1 (fr) * | 1987-10-19 | 1990-03-09 | Bioeurope | Derives de la l-tyrosine solubles dans l'eau et procede pour leur preparation |
| US5587507A (en) * | 1995-03-31 | 1996-12-24 | Rutgers, The State University | Synthesis of tyrosine derived diphenol monomers |
| US5216115A (en) * | 1990-06-12 | 1993-06-01 | Rutgers, The State University Of New Jersey | Polyarylate containing derivatives of the natural amino acid L-tyrosine |
| US5099060A (en) | 1990-06-12 | 1992-03-24 | Rutgers, The State University Of New Jersey | Synthesis of amino acid-derived bioerodible polymers |
| US5198507A (en) * | 1990-06-12 | 1993-03-30 | Rutgers, The State University Of New Jersey | Synthesis of amino acid-derived bioerodible polymers |
| AU729552B2 (en) * | 1997-02-18 | 2001-02-01 | Rutgers, The State University | Monomers derived from hydroxy acids and polymers prepared therefrom |
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1998
- 1998-02-18 AU AU61735/98A patent/AU729552B2/en not_active Expired
- 1998-02-18 US US09/367,735 patent/US6284862B1/en not_active Expired - Lifetime
- 1998-02-18 CA CA002281614A patent/CA2281614C/en not_active Expired - Lifetime
- 1998-02-18 EP EP98906536A patent/EP0961801B1/en not_active Expired - Lifetime
- 1998-02-18 JP JP53600898A patent/JP4410857B2/ja not_active Expired - Fee Related
- 1998-02-18 WO PCT/US1998/003127 patent/WO1998036013A1/en not_active Ceased
- 1998-02-18 DE DE69821600T patent/DE69821600T2/de not_active Expired - Lifetime
- 1998-02-18 MX MXPA99007662A patent/MXPA99007662A/es unknown
- 1998-02-18 AT AT98906536T patent/ATE259386T1/de not_active IP Right Cessation
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| Publication number | Publication date |
|---|---|
| US6284862B1 (en) | 2001-09-04 |
| CA2281614C (en) | 2008-11-18 |
| EP0961801A1 (en) | 1999-12-08 |
| JP2010006820A (ja) | 2010-01-14 |
| AU729552B2 (en) | 2001-02-01 |
| JP4411355B2 (ja) | 2010-02-10 |
| EP0961801B1 (en) | 2004-02-11 |
| DE69821600T2 (de) | 2005-01-05 |
| DE69821600D1 (de) | 2004-03-18 |
| CA2281614A1 (en) | 1998-08-20 |
| MXPA99007662A (es) | 2002-07-22 |
| AU6173598A (en) | 1998-09-08 |
| JP2001514618A (ja) | 2001-09-11 |
| EP0961801A4 (en) | 2000-05-03 |
| JP2009019040A (ja) | 2009-01-29 |
| WO1998036013A1 (en) | 1998-08-20 |
| ATE259386T1 (de) | 2004-02-15 |
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