JP4351676B2 - 空中浮遊病原体検出システム - Google Patents
空中浮遊病原体検出システム Download PDFInfo
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- JP4351676B2 JP4351676B2 JP2005507651A JP2005507651A JP4351676B2 JP 4351676 B2 JP4351676 B2 JP 4351676B2 JP 2005507651 A JP2005507651 A JP 2005507651A JP 2005507651 A JP2005507651 A JP 2005507651A JP 4351676 B2 JP4351676 B2 JP 4351676B2
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- 238000001514 detection method Methods 0.000 title claims description 28
- 244000000022 airborne pathogen Species 0.000 title description 10
- 239000002245 particle Substances 0.000 claims description 163
- 230000003287 optical effect Effects 0.000 claims description 29
- 238000009826 distribution Methods 0.000 claims description 28
- 244000052769 pathogen Species 0.000 claims description 26
- 230000001717 pathogenic effect Effects 0.000 claims description 21
- 239000003570 air Substances 0.000 claims description 17
- 239000004065 semiconductor Substances 0.000 claims description 11
- 239000012080 ambient air Substances 0.000 claims description 8
- 238000012545 processing Methods 0.000 claims description 6
- 230000000903 blocking effect Effects 0.000 claims description 3
- 230000007423 decrease Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 description 11
- 239000010425 asbestos Substances 0.000 description 9
- ATBAMAFKBVZNFJ-UHFFFAOYSA-N beryllium atom Chemical compound [Be] ATBAMAFKBVZNFJ-UHFFFAOYSA-N 0.000 description 9
- 229910052895 riebeckite Inorganic materials 0.000 description 9
- 239000000428 dust Substances 0.000 description 7
- 241000193738 Bacillus anthracis Species 0.000 description 5
- 239000013566 allergen Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 238000013461 design Methods 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 238000005192 partition Methods 0.000 description 3
- 241000607479 Yersinia pestis Species 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 229910052790 beryllium Inorganic materials 0.000 description 2
- 239000012620 biological material Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000000356 contaminant Substances 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 230000004313 glare Effects 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 241000193155 Clostridium botulinum Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010065042 Immune reconstitution inflammatory syndrome Diseases 0.000 description 1
- 206010035148 Plague Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 239000013572 airborne allergen Substances 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000001499 laser induced fluorescence spectroscopy Methods 0.000 description 1
- 231100000518 lethal Toxicity 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
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- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
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- 230000001052 transient effect Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
Images
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/22—Devices for withdrawing samples in the gaseous state
- G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/22—Devices for withdrawing samples in the gaseous state
- G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
- G01N2001/222—Other features
- G01N2001/2223—Other features aerosol sampling devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/019—Biological contaminants; Fouling
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Optical Measuring Cells (AREA)
Description
であり、その内容は本明細書の一部を構成するものとしてここに援用される。光学システムは、管状またはその他の形状である外部筐体30を備える。光源12は、コリメートされたレーザ光線32が筐体内の空気サンプル領域34を通過するように指向せしめる。コリメートされた光線が空気サンプル中の粒子35に衝突すると、光線の一部が、粒子の寸法に依存する反射角度で、反射または散乱される。そのため、光線の散乱された部分(散乱光)36は空気サンプル中に粒子が存在することを示す。環境空気は、上記の参考特許に記載されたのと同じように、ファン装置37により図1の矢印方向にサンプル領域34を通って吸い込まれる。
出力信号「ピーク出力」は、選別のためにウインドウコンパレータ装置に送られる。図5A中に示されるその他のパルスは、ウインドウコンパレータに計数を行い記憶するように命じるタイミング信号およびイネーブル信号である。
Claims (5)
- 環境空気を収容するためのサンプル領域を有する外部筐体と、
サンプル領域の一方側から可視光を発して、サンプル空気を通過するように収束光線を指向させ、サンプル領域中に存在する種々の寸法の粒子により光線の一部が種々の角度に散乱されると共に、光線の非散乱光を散乱されないままにする可視半導体レーザ光源と、
サンプル領域の他方側にある光線遮光装置であって、光線の非散乱光を遮光し、散乱光を光路に沿って指向させる光線遮光装置と、
前記光線遮光装置により検出器上に指向された光を検出し、かつ各パルスが粒径に比例する高さを有する出力パルスを生成する、前記光線遮光装置の下流側の光路中に位置する第1の光検出器と、
光線の非散乱光の光路中にあり且つ前記光線遮光装置の前面に位置して光路中の非散乱光を反射する反射器と、
前記反射器から反射される光を検出するように位置する第2の光検出器と、
前記第1の光検出器と前記第2の光検出器の出力が接続されて、前記第1の光検出器の出力を前記第2の光検出器の出力で除算して、散乱光のピーク値を表す出力パルス信号を生成する差動増幅器と、
前記差動増幅器の前記出力パルス信号を用いて粒子の寸法を求めて、所定時間における空気サンプル中で検出される空中浮遊粒子の粒径分布を得るパルス高さ判別器と、
前記パルス高さ判別器に接続されて、1〜7μmの範囲の所定病原体寸法の粒子数が所定の通常レベルを超えると警告信号を発生する警報装置と、
を備える病原体検出システム。 - 前記パルス高さ判別器の出力に接続されている処理装置であって、各パルスの高さに基づいて所定時間における粒径分布を処理し、空中浮遊粒子の粒径分布のヒストグラムを生成し、出力装置上にヒストグラムを表示する処理装置を備える請求項1に記載のシステム。
- 前記第2の光検出器の出力に接続されて光源の出力パワーの減少を検出するパワーモニターと、パワーモニターに接続されて光源のパワーが所定レベルよりも低下すると警報信号を発生する警報器とを備える請求項1に記載のシステム。
- 前記サンプル領域と前記光線遮光装置との間に位置する透明な隔壁スライドを備える請求項1に記載のシステム。
- 前記隔壁スライドが筺体中に取り外し可能に設置される請求項4に記載のシステム。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/325,528 US7053783B2 (en) | 2002-12-18 | 2002-12-18 | Pathogen detector system and method |
PCT/US2003/035407 WO2005015170A1 (en) | 2002-12-18 | 2003-11-07 | Airborne pathogen detector system and method |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2006511822A JP2006511822A (ja) | 2006-04-06 |
JP4351676B2 true JP4351676B2 (ja) | 2009-10-28 |
Family
ID=34134943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005507651A Expired - Fee Related JP4351676B2 (ja) | 2002-12-18 | 2003-11-07 | 空中浮遊病原体検出システム |
Country Status (7)
Country | Link |
---|---|
US (1) | US7053783B2 (ja) |
EP (1) | EP1573300A1 (ja) |
JP (1) | JP4351676B2 (ja) |
KR (1) | KR20050113598A (ja) |
CN (1) | CN1726387A (ja) |
AU (1) | AU2003304405A1 (ja) |
WO (1) | WO2005015170A1 (ja) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6784981B1 (en) * | 2000-06-02 | 2004-08-31 | Idexx Laboratories, Inc. | Flow cytometry-based hematology system |
US7973936B2 (en) * | 2001-01-30 | 2011-07-05 | Board Of Trustees Of Michigan State University | Control system and apparatus for use with ultra-fast laser |
US7450618B2 (en) * | 2001-01-30 | 2008-11-11 | Board Of Trustees Operating Michigan State University | Laser system using ultrashort laser pulses |
US7583710B2 (en) * | 2001-01-30 | 2009-09-01 | Board Of Trustees Operating Michigan State University | Laser and environmental monitoring system |
US7567596B2 (en) * | 2001-01-30 | 2009-07-28 | Board Of Trustees Of Michigan State University | Control system and apparatus for use with ultra-fast laser |
US8208505B2 (en) * | 2001-01-30 | 2012-06-26 | Board Of Trustees Of Michigan State University | Laser system employing harmonic generation |
CN100595564C (zh) * | 2004-07-30 | 2010-03-24 | 百维吉伦特系统有限公司 | 病原体和粒子检测器系统和方法 |
US7770224B2 (en) * | 2004-10-18 | 2010-08-03 | Lockheed Martin Corporation | CBRN attack detection system and method I |
WO2006088841A1 (en) * | 2005-02-14 | 2006-08-24 | Board Of Trustees Of Michigan State University | Ultra-fast laser system |
JP2007006931A (ja) * | 2005-06-28 | 2007-01-18 | Hirayama Setsubi Kk | 建物空間内に於ける浮遊微生物の検出除去方法とその装置 |
KR101283071B1 (ko) * | 2005-07-15 | 2013-07-05 | 바이오비질런트 시스템즈 인코포레이티드 | 병원체 및 입자 검출기 시스템 및 방법 |
US20080241935A1 (en) * | 2007-03-27 | 2008-10-02 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Methods for pathogen detection |
US20080193919A1 (en) * | 2005-11-30 | 2008-08-14 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems and methods for receiving pathogen related information and responding |
US20080241909A1 (en) * | 2007-03-27 | 2008-10-02 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Microfluidic chips for pathogen detection |
US20080179255A1 (en) * | 2007-01-29 | 2008-07-31 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Fluidic devices |
US20080241000A1 (en) * | 2007-03-27 | 2008-10-02 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for pathogen detection |
US8618470B2 (en) * | 2005-11-30 | 2013-12-31 | Board Of Trustees Of Michigan State University | Laser based identification of molecular characteristics |
US20080178692A1 (en) * | 2007-01-29 | 2008-07-31 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Fluidic methods |
US9018562B2 (en) * | 2006-04-10 | 2015-04-28 | Board Of Trustees Of Michigan State University | Laser material processing system |
US20090268201A1 (en) * | 2006-05-01 | 2009-10-29 | Patrick Call | Integrated mold detector |
JP5388846B2 (ja) | 2006-06-27 | 2014-01-15 | バイオヴィジラント システムズ インコーポレイテッド | 粒度および蛍光の同時測定による病原体検出 |
WO2008011059A1 (en) * | 2006-07-20 | 2008-01-24 | Board Of Trustees Of Michigan State University | Laser plasmonic system |
US20080245740A1 (en) * | 2007-01-29 | 2008-10-09 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Fluidic methods |
US20090050569A1 (en) * | 2007-01-29 | 2009-02-26 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Fluidic methods |
US20090215157A1 (en) * | 2007-03-27 | 2009-08-27 | Searete Llc | Methods for pathogen detection |
CN101911139B (zh) * | 2007-11-16 | 2013-03-20 | 粒子监测系统有限公司 | 用于光学粒子计数器的校准验证的系统和方法 |
US8628976B2 (en) * | 2007-12-03 | 2014-01-14 | Azbil BioVigilant, Inc. | Method for the detection of biologic particle contamination |
WO2009073649A1 (en) * | 2007-12-04 | 2009-06-11 | Particle Measuring Systems, Inc. | Non-orthogonal particle detection systems and methods |
US20110036995A1 (en) * | 2007-12-13 | 2011-02-17 | Biovigilant Systems, Inc. | Pathogen detection by simultaneous size/fluorescence measurement |
WO2009086122A2 (en) | 2007-12-21 | 2009-07-09 | Board Of Trustees Of Michigan State University | Control in ultrashort laser systems by a deformable mirror in the stretcher |
WO2010080642A1 (en) * | 2008-12-18 | 2010-07-15 | Biovigilant Systems, Inc. | Compact detector for simultaneous particle size and fluorescence detection |
US8675699B2 (en) * | 2009-01-23 | 2014-03-18 | Board Of Trustees Of Michigan State University | Laser pulse synthesis system |
WO2010141128A2 (en) | 2009-03-05 | 2010-12-09 | Board Of Trustees Of Michigan State University | Laser amplification system |
US8630322B2 (en) * | 2010-03-01 | 2014-01-14 | Board Of Trustees Of Michigan State University | Laser system for output manipulation |
KR20120071453A (ko) * | 2010-12-23 | 2012-07-03 | 삼성전자주식회사 | 미생물 검출장치 |
CN103492585A (zh) | 2011-04-06 | 2014-01-01 | 即时生物检测有限公司 | 微生物检测装置和方法 |
JP6080362B2 (ja) * | 2012-02-01 | 2017-02-15 | 株式会社島津製作所 | 粒子径計測装置 |
KR101411428B1 (ko) * | 2012-07-12 | 2014-06-24 | 한국과학기술원 | 집광식 휴대용 형광 검출 시스템 |
JP5952146B2 (ja) * | 2012-09-18 | 2016-07-13 | アズビル株式会社 | 粒子検出装置のメンテナンス費用算出システム及び粒子検出装置のメンテナンス費用算出方法 |
US20220042899A1 (en) * | 2013-03-15 | 2022-02-10 | Particles Plus, Inc. | Particle counter with integrated bootloader |
US10983040B2 (en) | 2013-03-15 | 2021-04-20 | Particles Plus, Inc. | Particle counter with integrated bootloader |
US10352844B2 (en) | 2013-03-15 | 2019-07-16 | Particles Plus, Inc. | Multiple particle sensors in a particle counter |
US9158652B2 (en) * | 2013-03-15 | 2015-10-13 | Particles Plus, Inc. | Intelligent modules in a particle counter |
US9157847B2 (en) * | 2013-03-15 | 2015-10-13 | Particles Plus, Inc. | Mixed-mode photo-amplifier for particle counter |
US11579072B2 (en) | 2013-03-15 | 2023-02-14 | Particles Plus, Inc. | Personal air quality monitoring system |
US9677990B2 (en) | 2014-04-30 | 2017-06-13 | Particles Plus, Inc. | Particle counter with advanced features |
US9141094B2 (en) * | 2013-03-15 | 2015-09-22 | Particles Plus, Inc. | Personal air quality monitoring system |
DE102013220004A1 (de) | 2013-10-02 | 2015-04-02 | Siemens Aktiengesellschaft | Vorrichtung und Verfahren zum Bestimmen von Größen von Partikeln in einem Fluid |
WO2015146429A1 (ja) * | 2014-03-25 | 2015-10-01 | 株式会社島津製作所 | パーティクル計数装置 |
EP2957898A1 (de) * | 2014-06-17 | 2015-12-23 | Siemens Healthcare Diagnostics Products GmbH | Streulichtmesssystem mit einer Küvette und zwei Blenden, wobei das am Eingangs- und am Ausgangsfenster der Küvette erzeugte Streulicht auf je eine der beiden Blenden fokussiert wird |
JP6705585B2 (ja) | 2015-04-02 | 2020-06-03 | パーティクル・メージャーリング・システムズ・インコーポレーテッド | 粒子計数器におけるレーザノイズ検出及び緩和 |
CN106556557A (zh) * | 2015-09-29 | 2017-04-05 | 中国辐射防护研究院 | 一种测量气溶胶浓度的光学测量腔 |
CN105259086B (zh) * | 2015-10-29 | 2018-03-27 | 广东美的制冷设备有限公司 | 粉尘浓度的检测方法及检测系统 |
CN105510201A (zh) * | 2015-12-17 | 2016-04-20 | 常熟市矿山机电器材有限公司 | 一种自动感应粉尘浓度的警报系统 |
US9851291B2 (en) | 2016-05-02 | 2017-12-26 | Hamilton Associates, Inc. | Realtime optical method and system for detecting and classifying biological and non-biological particles |
CN109313114B (zh) | 2016-05-20 | 2021-08-20 | 粒子监测系统有限公司 | 具有流量和气泡检测系统的自动功率控制液体颗粒计数器 |
US10197487B2 (en) | 2016-06-03 | 2019-02-05 | Particle Measuring Systems, Inc. | Systems and methods for isolating condensate in a condensation particle counter |
WO2019191419A2 (en) | 2018-03-30 | 2019-10-03 | Idexx Laboratories, Inc. | Flow cytometer, laser optics assembly thereof, and methods of assembling the same |
WO2020102038A1 (en) | 2018-11-12 | 2020-05-22 | Particle Measuring Systems, Inc. | Calibration verification for optical particle analyzers |
US11385161B2 (en) | 2018-11-12 | 2022-07-12 | Particle Measuring Systems, Inc. | Calibration verification for optical particle analyzers |
US12002665B2 (en) * | 2019-07-01 | 2024-06-04 | Applied Materials, Inc. | Real-time detection of particulate matter during deposition chamber manufacturing |
KR102547788B1 (ko) | 2020-06-17 | 2023-06-26 | 아이덱스 래보러토리즈, 인코포레이티드 | 플로우 사이토미터 및 그 레이저 광학 어셈블리 |
US11988591B2 (en) | 2020-07-01 | 2024-05-21 | Particles Plus, Inc. | Modular optical particle counter sensor and apparatus |
DE102021111494A1 (de) | 2021-05-04 | 2022-11-10 | Atral-Secal Gmbh | Nachweisgerät sowie ein Nachweisverfahren für in Luft enthaltene pathogene Substanzen |
WO2022261314A1 (en) * | 2021-06-09 | 2022-12-15 | University Of Utah Research Foundation | Airborne virus sensors |
DE102021126818A1 (de) | 2021-10-15 | 2023-04-20 | Atral-Secal Gmbh | Nachweisgerät sowie ein Nachweisverfahren für in Luft enthaltene pathogene Substanzen |
DE102022132609A1 (de) | 2022-12-08 | 2024-06-13 | Hager Safety Deutschland Gmbh | Nachweisgerät sowie ein Nachweisverfahren für in Luft enthaltene pathogene Substanzen |
Family Cites Families (103)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3867640A (en) * | 1972-03-09 | 1975-02-18 | Levy Co Edward C | Dust sampling system |
US3845480A (en) * | 1973-02-20 | 1974-10-29 | Air Technologies Inc | Particulate detector system |
CH592933A5 (ja) * | 1976-04-05 | 1977-11-15 | Cerberus Ag | |
US4177482A (en) * | 1977-04-21 | 1979-12-04 | Eastman Kodak Company | Population and profile data of bodies in a transparent mass |
US4226533A (en) * | 1978-09-11 | 1980-10-07 | General Electric Company | Optical particle detector |
US4286876A (en) * | 1979-01-02 | 1981-09-01 | Coulter Electronics, Inc. | Apparatus and method for measuring scattering of light in particle detection systems |
US4583859A (en) * | 1984-03-30 | 1986-04-22 | The Babcock & Wilcox Company | Filter cleaning system for opacity monitor |
GB8523747D0 (en) * | 1985-09-26 | 1985-10-30 | Vg Instr Group | Fibre size monitor |
US4728190A (en) * | 1985-10-15 | 1988-03-01 | Particle Measuring Systems, Inc. | Device and method for optically detecting particles in a fluid |
JPS62220833A (ja) * | 1986-03-22 | 1987-09-29 | Sigma Tec:Kk | 光散乱式微粒子センサ |
US4830494A (en) * | 1986-07-10 | 1989-05-16 | Kowa Company Ltd. | Method and apparatus for measuring particles in a fluid |
DE3628072A1 (de) * | 1986-08-19 | 1987-04-09 | Fruengel Frank Dr Ing | Aerosol- und feinstaubmessgeraet nach dem streulichtprinzip |
KR970007077B1 (ko) * | 1987-03-13 | 1997-05-02 | 코울터 일렉트로닉스 인커퍼레이티드 | 광산란 기술을 이용한 다중-부분식별 분석 방법 |
JP2529966B2 (ja) * | 1987-03-28 | 1996-09-04 | 株式会社東芝 | 粒径測定装置 |
US4849340A (en) | 1987-04-03 | 1989-07-18 | Cardiovascular Diagnostics, Inc. | Reaction system element and method for performing prothrombin time assay |
US5123731A (en) * | 1988-02-01 | 1992-06-23 | Canon Kabushiki Kaisha | Particle measuring device |
JP2674704B2 (ja) * | 1988-06-07 | 1997-11-12 | 東亜医用電子株式会社 | 二次元分布分画方法 |
JP2674705B2 (ja) * | 1988-06-10 | 1997-11-12 | 東亜医用電子株式会社 | 一次元分布分画方法 |
JPH02170053A (ja) | 1988-12-23 | 1990-06-29 | Meiji Seika Kaisha Ltd | 微生物の検出方法及び装置 |
US5101113A (en) * | 1989-05-16 | 1992-03-31 | Arizona Board Of Regents | Ensemble scattering particle sizing system with axial spatial resolution |
US5121988A (en) * | 1989-10-04 | 1992-06-16 | Tsi Incorporated | Single particle detector method and apparatus utilizing light extinction within a sheet of light |
DE69025256T2 (de) | 1989-10-11 | 1996-06-27 | Canon Kk | Gerät und Verfahren zur Trennung von Teilchen aus flüssigkeitssuspendierten Teilchen in Zusammenhang mit deren Eigenschaften |
US5085500A (en) * | 1989-11-28 | 1992-02-04 | Tsi Incorporated | Non-imaging laser particle counter |
JP2815435B2 (ja) | 1989-12-22 | 1998-10-27 | 株式会社日立製作所 | 粒子解析装置及び血球カウンタ |
US5083865A (en) * | 1990-05-11 | 1992-01-28 | Applied Materials, Inc. | Particle monitor system and method |
JP2899360B2 (ja) * | 1990-05-21 | 1999-06-02 | 興和株式会社 | 流体中の粒子計測方法及びその装置 |
GB9014015D0 (en) | 1990-06-23 | 1990-08-15 | Dennis Peter N J | Improvements in or relating to smoke detectors |
US5132548A (en) | 1990-09-14 | 1992-07-21 | High Yield Technology | High sensitivity, large detection area particle sensor for vacuum applications |
US5266798A (en) | 1990-09-14 | 1993-11-30 | High Yield Technology | High sensitivity, large detection area particle sensor for vacuum applications |
JPH0619319B2 (ja) * | 1990-11-09 | 1994-03-16 | 近藤工業株式会社 | 気中微粒子監視報知機 |
US5286452A (en) | 1991-05-20 | 1994-02-15 | Sienna Biotech, Inc. | Simultaneous multiple assays |
JP2507483Y2 (ja) * | 1991-08-17 | 1996-08-14 | 株式会社堀場製作所 | レ―ザ回折式粒度分布測定装置 |
JP3215175B2 (ja) | 1992-08-10 | 2001-10-02 | シスメックス株式会社 | 粒子分析装置 |
US5315115A (en) * | 1992-08-10 | 1994-05-24 | Gerber Hermann E | Optical apparatus and method for sensing particulates |
US5383024A (en) * | 1992-08-12 | 1995-01-17 | Martin Marietta Energy Systems, Inc. | Optical wet steam monitor |
ATE156312T1 (de) | 1992-10-27 | 1997-08-15 | Canon Kk | Verfahren zum fördern von flüssigkeiten |
US5426501A (en) * | 1993-01-06 | 1995-06-20 | Laser Sensor Technology, Inc. | Apparatus and method for particle analysis |
US5456102A (en) | 1993-03-19 | 1995-10-10 | Moorehead; Jack | Method and apparatus for particle counting and counter calibration |
US5448364A (en) | 1993-03-22 | 1995-09-05 | Estek Corporation | Particle detection system with reflective line-to-spot collector |
US5481357A (en) | 1994-03-03 | 1996-01-02 | International Business Machines Corporation | Apparatus and method for high-efficiency, in-situ particle detection |
US5416580A (en) * | 1993-07-07 | 1995-05-16 | General Signal Corporation | Methods and apparatus for determining small particle size distribution utilizing multiple light beams |
JPH09500968A (ja) | 1993-08-19 | 1997-01-28 | ヴェンチュアダイン リミテッド | 低圧力損失の空気流系を有する粒子センサー |
JP3328032B2 (ja) | 1993-11-04 | 2002-09-24 | シスメックス株式会社 | 粒子分析装置 |
US5428964A (en) * | 1994-01-10 | 1995-07-04 | Tec-Way Air Quality Products Inc. | Control for air quality machine |
US5561515A (en) | 1994-10-07 | 1996-10-01 | Tsi Incorporated | Apparatus for measuring particle sizes and velocities |
US6984526B2 (en) | 1995-02-08 | 2006-01-10 | University Of South Florida | Spectrophotometric method for determining the viability of a sample containing platelets |
US5684585A (en) * | 1995-09-22 | 1997-11-04 | Met One, Inc. | Optical particle counter employing a field-calibrator |
NL1001369C2 (nl) * | 1995-10-06 | 1997-04-08 | Univ Delft Tech | Werkwijze en inrichting voor het meten van deeltjesgrootte bij lage concentratie. |
US5953477A (en) | 1995-11-20 | 1999-09-14 | Visionex, Inc. | Method and apparatus for improved fiber optic light management |
US5642193A (en) * | 1996-03-08 | 1997-06-24 | Met One, Inc. | Particle counter employing a solid-state laser with an intracavity view volume |
US6586193B2 (en) | 1996-04-25 | 2003-07-01 | Genicon Sciences Corporation | Analyte assay using particulate labels |
US6087947A (en) * | 1996-07-11 | 2000-07-11 | Robert N. Hamburger | Allergen detector system and method |
US5646597A (en) | 1996-07-11 | 1997-07-08 | Robert N. Hamburger | Allergen detector system and method |
WO1998010289A1 (en) | 1996-09-04 | 1998-03-12 | The Penn State Research Foundation | Self-assembled metal colloid monolayers |
US5943130A (en) * | 1996-10-21 | 1999-08-24 | Insitec, Inc. | In situ sensor for near wafer particle monitoring in semiconductor device manufacturing equipment |
WO1999001748A1 (en) * | 1997-07-03 | 1999-01-14 | Hamburger, Robert, N. | Allergen detector system and method |
US5986555A (en) * | 1997-10-07 | 1999-11-16 | Robert N. Hamburger | Allergen detector system and method |
US5969622A (en) * | 1997-10-07 | 1999-10-19 | Robert N. Hamburger | Allergen detector system and method |
US5995686A (en) | 1997-12-16 | 1999-11-30 | Hamburger; Robert N. | Fiber-optic sensor device and method |
US6699724B1 (en) | 1998-03-11 | 2004-03-02 | Wm. Marsh Rice University | Metal nanoshells for biosensing applications |
US5946093A (en) * | 1998-08-19 | 1999-08-31 | Met One, Inc. | Particle detection system and method employing an upconversion laser |
CA2341359A1 (en) | 1998-08-21 | 2000-03-02 | Ian Walton | Novel optical architectures for microvolume laser-scanning cytometers |
US7057732B2 (en) | 1999-01-25 | 2006-06-06 | Amnis Corporation | Imaging platform for nanoparticle detection applied to SPR biomolecular interaction analysis |
US6404497B1 (en) | 1999-01-25 | 2002-06-11 | Massachusetts Institute Of Technology | Polarized light scattering spectroscopy of tissue |
WO2000050887A1 (de) | 1999-02-22 | 2000-08-31 | Evotec Biosystems Ag | Verwendung von trägermaterial in der kapillar-elektrochromatographie |
US6687395B1 (en) | 1999-07-21 | 2004-02-03 | Surromed, Inc. | System for microvolume laser scanning cytometry |
US7126687B2 (en) | 1999-08-09 | 2006-10-24 | The United States Of America As Represented By The Secretary Of The Army | Method and instrumentation for determining absorption and morphology of individual airborne particles |
US6664550B2 (en) | 1999-08-30 | 2003-12-16 | Sandia National Laboratories | Apparatus to collect, classify, concentrate, and characterize gas-borne particles |
US6386015B1 (en) * | 1999-08-30 | 2002-05-14 | Sandia Corporation | Apparatus to collect, classify, concentrate, and characterize gas-borne particles |
US6677431B2 (en) | 1999-12-10 | 2004-01-13 | The Trustees Of The University Of Pennsylvania | Design, preparation, and properties of antibacterial β-peptides |
US6530944B2 (en) | 2000-02-08 | 2003-03-11 | Rice University | Optically-active nanoparticles for use in therapeutic and diagnostic methods |
US6639674B2 (en) | 2000-03-28 | 2003-10-28 | Board Of Regents, The University Of Texas System | Methods and apparatus for polarized reflectance spectroscopy |
US6766184B2 (en) | 2000-03-28 | 2004-07-20 | Board Of Regents, The University Of Texas System | Methods and apparatus for diagnostic multispectral digital imaging |
JP4136263B2 (ja) * | 2000-03-31 | 2008-08-20 | シスメックス株式会社 | 粒子測定装置および粒子測定方法 |
JP2001318054A (ja) * | 2000-05-11 | 2001-11-16 | Matsushita Electric Ind Co Ltd | インク材料中の凝集物検出方法および検出装置 |
US6490530B1 (en) * | 2000-05-23 | 2002-12-03 | Wyatt Technology Corporation | Aerosol hazard characterization and early warning network |
JP3574045B2 (ja) * | 2000-05-31 | 2004-10-06 | 紀本電子工業株式会社 | 浮遊粒子状物質の連続測定装置 |
US6784981B1 (en) | 2000-06-02 | 2004-08-31 | Idexx Laboratories, Inc. | Flow cytometry-based hematology system |
AU2001271976A1 (en) | 2000-07-07 | 2002-01-21 | Corixa Corporation | Microspheres and adjuvants for dna vaccine delivery |
WO2003106965A2 (en) * | 2001-01-10 | 2003-12-24 | S3I L.L.C. | System and method for detecting and classifying biological particles |
US6697652B2 (en) | 2001-01-19 | 2004-02-24 | Massachusetts Institute Of Technology | Fluorescence, reflectance and light scattering spectroscopy for measuring tissue |
US7361472B2 (en) | 2001-02-23 | 2008-04-22 | Invitrogen Corporation | Methods for providing extended dynamic range in analyte assays |
US20020165456A1 (en) | 2001-03-26 | 2002-11-07 | Murat Canpolat | Estimation of the average size of white light scatterers in normal and cancerous tissue using light scattering spectrum |
EP1395826A4 (en) | 2001-05-17 | 2005-11-09 | Miltenyi Biotec Gmbh | ANTIGEN-BINDING FRAGMENTS FOR A SUB-GROUP OF DENDRITIC CELLS AND USE THEREOF |
US20030077627A1 (en) | 2001-07-19 | 2003-04-24 | Worthington Mark Oscar | Transmissive optical disc assemblies for performing physical measurements and methods relating thereto |
US7061622B2 (en) | 2001-08-03 | 2006-06-13 | Case Western Reserve University | Aspects of basic OCT engine technologies for high speed optical coherence tomography and light source and other improvements in optical coherence tomography |
US20030049866A1 (en) | 2001-09-05 | 2003-03-13 | Genicon Sciences Corporation | Sample device preservation |
CA2459570A1 (en) | 2001-09-05 | 2003-03-13 | Genicon Sciences Corporation | Apparatus for reading signals generated from resonance light scattered particle labels |
EP1437975B1 (en) | 2001-09-26 | 2011-08-10 | Rice University | Optically-absorbing nanoparticles for enhanced tissue repair |
US7260483B2 (en) | 2001-10-25 | 2007-08-21 | The Regents Of The University Of California | Real-time detection method and system for identifying individual aerosol particles |
US6831279B2 (en) | 2001-11-27 | 2004-12-14 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence | Laser diode-excited biological particle detection system |
EP1495292A4 (en) | 2001-12-21 | 2012-05-09 | Malvern Instr Inc | MONITORING A SPECTROMETRIC PROCESS |
EP1472517A1 (en) | 2002-01-18 | 2004-11-03 | Newton Laboratories, Inc. | Spectroscopic diagnostic methods and system |
WO2003062799A2 (en) | 2002-01-18 | 2003-07-31 | Newton Laboratories, Inc. | Spectroscopic diagnostic methods and system |
US20040072356A1 (en) | 2002-02-20 | 2004-04-15 | Guillermo Senisterra | Methods and apparatuses for characterizing stability of biological molecules |
US6694799B2 (en) | 2002-02-22 | 2004-02-24 | Eastern Washington University | Method and apparatus for detection of particles |
US7863038B2 (en) | 2002-03-29 | 2011-01-04 | Board Of Regents, The University Of Texas System | Implantable biosensor from stratified nanostructured membranes |
US20040073120A1 (en) | 2002-04-05 | 2004-04-15 | Massachusetts Institute Of Technology | Systems and methods for spectroscopy of biological tissue |
JP2005524084A (ja) | 2002-04-30 | 2005-08-11 | ユニバーシティ オブ メリーランド,ボルチモア | 蛍光検出法 |
GB2409036B (en) | 2002-06-24 | 2006-02-15 | Tsi Inc | Analysis systems detecting particle size and fluorescence |
US6794671B2 (en) * | 2002-07-17 | 2004-09-21 | Particle Sizing Systems, Inc. | Sensors and methods for high-sensitivity optical particle counting and sizing |
US6743634B2 (en) | 2002-08-23 | 2004-06-01 | Coulter International Corp. | Method and apparatus for differentiating blood cells using back-scatter |
US7122384B2 (en) | 2002-11-06 | 2006-10-17 | E. I. Du Pont De Nemours And Company | Resonant light scattering microparticle methods |
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AU2003304405A1 (en) | 2005-02-25 |
US7053783B2 (en) | 2006-05-30 |
KR20050113598A (ko) | 2005-12-02 |
WO2005015170A1 (en) | 2005-02-17 |
US20060071803A1 (en) | 2006-04-06 |
EP1573300A1 (en) | 2005-09-14 |
CN1726387A (zh) | 2006-01-25 |
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